MicroRNAs in development and cancer:
MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of...
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
London
Imperial College Press
c2011
|
| Schriftenreihe: | Molecular medicine and medicinal chemistry
v. 1 |
| Schlagworte: | |
| Online-Zugang: | FHN01 URL des Erstveroeffentlichers |
| Zusammenfassung: | MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represent a paradigm shift in thinking about gene regulation during development and disease, and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer |
| Beschreibung: | xv, 282 p. ill. (some col.) |
| ISBN: | 9781848163676 |
Internformat
MARC
| LEADER | 00000nmm a2200000zcb4500 | ||
|---|---|---|---|
| 001 | BV044633409 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 171120s2011 |||| o||u| ||||||eng d | ||
| 020 | |a 9781848163676 |c electronic bk. |9 978-1-84816-367-6 | ||
| 024 | 7 | |a 10.1142/P630 |2 doi | |
| 035 | |a (ZDB-124-WOP)00001171 | ||
| 035 | |a (OCoLC)1012708713 | ||
| 035 | |a (DE-599)BVBBV044633409 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-92 | ||
| 082 | 0 | |a 616.994 |2 22 | |
| 084 | |a WD 5355 |0 (DE-625)148201: |2 rvk | ||
| 084 | |a XH 1800 |0 (DE-625)152873:12905 |2 rvk | ||
| 245 | 1 | 0 | |a MicroRNAs in development and cancer |c editor, Frank J. Slack |
| 264 | 1 | |a London |b Imperial College Press |c c2011 | |
| 300 | |a xv, 282 p. |b ill. (some col.) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 490 | 0 | |a Molecular medicine and medicinal chemistry |v v. 1 | |
| 520 | |a MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represent a paradigm shift in thinking about gene regulation during development and disease, and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer | ||
| 650 | 4 | |a Cancer | |
| 650 | 4 | |a Small interfering RNA. | |
| 650 | 0 | 7 | |a Krebszelle |0 (DE-588)4128704-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a miRNS |0 (DE-588)7736808-3 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Krebszelle |0 (DE-588)4128704-6 |D s |
| 689 | 0 | 1 | |a miRNS |0 (DE-588)7736808-3 |D s |
| 689 | 0 | |8 1\p |5 DE-604 | |
| 700 | 1 | |a Slack, Frank J. |e Sonstige |4 oth | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 1848163665 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781848163669 |
| 856 | 4 | 0 | |u http://www.worldscientific.com/worldscibooks/10.1142/P630#t=toc |x Verlag |z URL des Erstveroeffentlichers |3 Volltext |
| 912 | |a ZDB-124-WOP | ||
| 999 | |a oai:aleph.bib-bvb.de:BVB01-030031381 | ||
| 883 | 1 | |8 1\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 966 | e | |u http://www.worldscientific.com/worldscibooks/10.1142/P630#t=toc |l FHN01 |p ZDB-124-WOP |q FHN_PDA_WOP |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804178043885846528 |
|---|---|
| any_adam_object | |
| building | Verbundindex |
| bvnumber | BV044633409 |
| classification_rvk | WD 5355 XH 1800 |
| collection | ZDB-124-WOP |
| ctrlnum | (ZDB-124-WOP)00001171 (OCoLC)1012708713 (DE-599)BVBBV044633409 |
| dewey-full | 616.994 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.994 |
| dewey-search | 616.994 |
| dewey-sort | 3616.994 |
| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Medizin |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02632nmm a2200493zcb4500</leader><controlfield tag="001">BV044633409</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">171120s2011 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781848163676</subfield><subfield code="c">electronic bk.</subfield><subfield code="9">978-1-84816-367-6</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1142/P630</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-124-WOP)00001171 </subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1012708713</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV044633409</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-92</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">616.994</subfield><subfield code="2">22</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WD 5355</subfield><subfield code="0">(DE-625)148201:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">XH 1800</subfield><subfield code="0">(DE-625)152873:12905</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">MicroRNAs in development and cancer</subfield><subfield code="c">editor, Frank J. Slack</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">London</subfield><subfield code="b">Imperial College Press</subfield><subfield code="c">c2011</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">xv, 282 p.</subfield><subfield code="b">ill. (some col.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Molecular medicine and medicinal chemistry</subfield><subfield code="v">v. 1</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represent a paradigm shift in thinking about gene regulation during development and disease, and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cancer</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Small interfering RNA.</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Krebszelle</subfield><subfield code="0">(DE-588)4128704-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">miRNS</subfield><subfield code="0">(DE-588)7736808-3</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Krebszelle</subfield><subfield code="0">(DE-588)4128704-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">miRNS</subfield><subfield code="0">(DE-588)7736808-3</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="8">1\p</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Slack, Frank J.</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">1848163665</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781848163669</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://www.worldscientific.com/worldscibooks/10.1142/P630#t=toc</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveroeffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-124-WOP</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-030031381</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">1\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">http://www.worldscientific.com/worldscibooks/10.1142/P630#t=toc</subfield><subfield code="l">FHN01</subfield><subfield code="p">ZDB-124-WOP</subfield><subfield code="q">FHN_PDA_WOP</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| id | DE-604.BV044633409 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T07:57:42Z |
| institution | BVB |
| isbn | 9781848163676 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030031381 |
| oclc_num | 1012708713 |
| open_access_boolean | |
| owner | DE-92 |
| owner_facet | DE-92 |
| physical | xv, 282 p. ill. (some col.) |
| psigel | ZDB-124-WOP ZDB-124-WOP FHN_PDA_WOP |
| publishDate | 2011 |
| publishDateSearch | 2011 |
| publishDateSort | 2011 |
| publisher | Imperial College Press |
| record_format | marc |
| series2 | Molecular medicine and medicinal chemistry |
| spelling | MicroRNAs in development and cancer editor, Frank J. Slack London Imperial College Press c2011 xv, 282 p. ill. (some col.) txt rdacontent c rdamedia cr rdacarrier Molecular medicine and medicinal chemistry v. 1 MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represent a paradigm shift in thinking about gene regulation during development and disease, and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer Cancer Small interfering RNA. Krebszelle (DE-588)4128704-6 gnd rswk-swf miRNS (DE-588)7736808-3 gnd rswk-swf Krebszelle (DE-588)4128704-6 s miRNS (DE-588)7736808-3 s 1\p DE-604 Slack, Frank J. Sonstige oth Erscheint auch als Druck-Ausgabe 1848163665 Erscheint auch als Druck-Ausgabe 9781848163669 http://www.worldscientific.com/worldscibooks/10.1142/P630#t=toc Verlag URL des Erstveroeffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | MicroRNAs in development and cancer Cancer Small interfering RNA. Krebszelle (DE-588)4128704-6 gnd miRNS (DE-588)7736808-3 gnd |
| subject_GND | (DE-588)4128704-6 (DE-588)7736808-3 |
| title | MicroRNAs in development and cancer |
| title_auth | MicroRNAs in development and cancer |
| title_exact_search | MicroRNAs in development and cancer |
| title_full | MicroRNAs in development and cancer editor, Frank J. Slack |
| title_fullStr | MicroRNAs in development and cancer editor, Frank J. Slack |
| title_full_unstemmed | MicroRNAs in development and cancer editor, Frank J. Slack |
| title_short | MicroRNAs in development and cancer |
| title_sort | micrornas in development and cancer |
| topic | Cancer Small interfering RNA. Krebszelle (DE-588)4128704-6 gnd miRNS (DE-588)7736808-3 gnd |
| topic_facet | Cancer Small interfering RNA. Krebszelle miRNS |
| url | http://www.worldscientific.com/worldscibooks/10.1142/P630#t=toc |
| work_keys_str_mv | AT slackfrankj micrornasindevelopmentandcancer |