MicroRNAs in development and cancer:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
London
Imperial College Press
c2011
|
| Schriftenreihe: | Molecular medicine and medicinal chemistry
1 |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | Includes bibliographical references and index Introduction to gene regulation by small RNAs -- The emerging non-coding RNA world -- MicroRNAs in C. elegans development -- MicroRNAs in mammalian development -- MicroRNAs in hematopoietic development -- MicroRNAs function as tumor suppressor genes and oncogenes -- Simultaneous detection of primary, precursor and mature microRNAs by qPCR -- Single nucleotide polymorphisms in microRNAs and microRNA binding sites with roles in cancer -- MicroRNAs as potential diagnostics and therapeutics -- MicroRNA target prediction -- Non-coding RNAs in cancer: the other part of the story "MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represent a paradigm shift in thinking about gene regulation during development and disease, and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer."--P. [4] of cover |
| Beschreibung: | 1 Online-Ressource (xv, 282 p.) |
| ISBN: | 9781848163676 1848163673 9781848163669 1848163665 |
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| id | DE-604.BV040471520 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T00:24:35Z |
| institution | BVB |
| isbn | 9781848163676 1848163673 9781848163669 1848163665 |
| language | English |
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| series2 | Molecular medicine and medicinal chemistry |
| spelling | MicroRNAs in development and cancer editor Frank J. Slack London Imperial College Press c2011 1 Online-Ressource (xv, 282 p.) txt rdacontent c rdamedia cr rdacarrier Molecular medicine and medicinal chemistry 1 Includes bibliographical references and index Introduction to gene regulation by small RNAs -- The emerging non-coding RNA world -- MicroRNAs in C. elegans development -- MicroRNAs in mammalian development -- MicroRNAs in hematopoietic development -- MicroRNAs function as tumor suppressor genes and oncogenes -- Simultaneous detection of primary, precursor and mature microRNAs by qPCR -- Single nucleotide polymorphisms in microRNAs and microRNA binding sites with roles in cancer -- MicroRNAs as potential diagnostics and therapeutics -- MicroRNA target prediction -- Non-coding RNAs in cancer: the other part of the story "MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represent a paradigm shift in thinking about gene regulation during development and disease, and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer."--P. [4] of cover Naturwissenschaft Small interfering RNA Cancer MicroRNAs Neoplasms / genetics Neoplasms / therapy Tumor Markers, Biological Science Natural history miRNS (DE-588)7736808-3 gnd rswk-swf Krebszelle (DE-588)4128704-6 gnd rswk-swf Krebszelle (DE-588)4128704-6 s miRNS (DE-588)7736808-3 s DE-604 Slack, Frank J. Sonstige oth Molecular medicine and medicinal chemistry 1 (DE-604)BV036891092 1 http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=374850 Verlag Volltext |
| spellingShingle | MicroRNAs in development and cancer Molecular medicine and medicinal chemistry Naturwissenschaft Small interfering RNA Cancer MicroRNAs Neoplasms / genetics Neoplasms / therapy Tumor Markers, Biological Science Natural history miRNS (DE-588)7736808-3 gnd Krebszelle (DE-588)4128704-6 gnd |
| subject_GND | (DE-588)7736808-3 (DE-588)4128704-6 |
| title | MicroRNAs in development and cancer |
| title_auth | MicroRNAs in development and cancer |
| title_exact_search | MicroRNAs in development and cancer |
| title_full | MicroRNAs in development and cancer editor Frank J. Slack |
| title_fullStr | MicroRNAs in development and cancer editor Frank J. Slack |
| title_full_unstemmed | MicroRNAs in development and cancer editor Frank J. Slack |
| title_short | MicroRNAs in development and cancer |
| title_sort | micrornas in development and cancer |
| topic | Naturwissenschaft Small interfering RNA Cancer MicroRNAs Neoplasms / genetics Neoplasms / therapy Tumor Markers, Biological Science Natural history miRNS (DE-588)7736808-3 gnd Krebszelle (DE-588)4128704-6 gnd |
| topic_facet | Naturwissenschaft Small interfering RNA Cancer MicroRNAs Neoplasms / genetics Neoplasms / therapy Tumor Markers, Biological Science Natural history miRNS Krebszelle |
| url | http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=374850 |
| volume_link | (DE-604)BV036891092 |
| work_keys_str_mv | AT slackfrankj micrornasindevelopmentandcancer |