MicroRNAs: key regulators of oncogenesis
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Cham [u.a.]
Springer
2014
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | XXVI, 433 S. Ill., graph. Darst. |
| ISBN: | 3319037242 9783319037240 |
Internformat
MARC
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Datensatz im Suchindex
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|---|---|
| adam_text | Contents
Part I MicroRNAs: Biology and Implications in Cancer
1
MicroRNAs and Cancer: An Overview
................................................. 3
Sadegh Babashah
2
Epigenetics, MicroRNAs and Human Cancer
...................................... 29
Jiazeng Xia, Xiaoqiang Guo, and Kaiyuan Deng
3
MicroRNAs, Diet and Cancer Chemoprevention
................................. 59
Shahana Majid, Siunit Arora, Rajvir Dahiya, and Sharanjot Saini
4
MicroRNAs and Energy Metabolism in Cancer Cells
......................... 83
Linchong Sun. Xiaoping He, Yang
Cao, Ping
Gao,
and Huafeng Zhang
5
MicroRNAs in Solid Tumors
.................................................................. 97
Gìanpiero Di Leva
and
Michela Garofalo
6
MicroRNAs and Blood Cancers
............................................................. 129
Charles H. Lawrie
7
MicroRNAs and Oncogenic Human Viruses
........................................ 155
Muriel Thirion,
Teru
Kanda,
Yoshiki Murakami,
Takahiro Ochiya, and Hisashi lizasa
8
MicroRNAs Linking Cancer and Inflammation:
Focos
on Liver Cancer
............................................................................ 183
Angélique Gougelet
and
Sabine Coînot
9
MicroRNAs and Regulatory Pathways in Tumorigenesis
................... 209
Jun
Wei, Yong
Lu
Xiaoming Liu, and William C. Cho
10
MicroRNA-Modulated Apoptotic and Antopnagic
Signaling Networks in Cancer
............................................,.................. 233
Bo Liu and Yu-quan Wei
x
Contents
11 MicroRNAs in
Cancer
Drug
Resistance
and Drug Sensitivity
........... 251
Hugo
Seca, Raquel
T.
Lima, and
M.
Helena
Vasconcelos
12
The Biological Roles of MicroRNAs in Cancer Stem Cells
................. 295
Bin
Bao,
Asfar
S.
Azmi. Aamir Ahmad, Yiwei Li,
Sanjeev Banerjee, Dejuan
Kong, Shadan Ali,
and Fazlul H.
Särkar
Part II MicroRNAs and Their Clinical Implications
13
MicroRNAs and Clinical Implications in Cancer
................................ 323
Jürgen Wittmann
14
MicroRNA Kxpression Profiling
and Its Clinical Impact in Breast Cancer
............................................. 355
Manuela Ferracin
and Laura
Lupini
15
MicroRNAs and Their Clinical Impact
on Resistance to
Anticancer
Treatment
................................................. 369
Kirsten
Lindner, Jocrg Haier, and Richard Hummel
16
Nanocarriers and MicroRNA-Based Scenarios
for Cancer Therapy
................................................................................. 387
Babak Bakhshinejad, Mohammad
Amin Javidi,
Sahar
Babashah, and Sadegh Babashah
17
Challenges and Strategies for Pulmonary
Delivery of MicroRNA-Based Therapeutics
......................................... 413
Yu Fujita, Kazuyoshi Kuwano, and Takahiro Ochiya
Index
................................................................................................................. 429
Sadegh Babashah Editor
MicroRMÄs: Key Regulators
of
Oncogenesis
Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new
layer of complexity to the understanding of development and progression of the disease
state. It has been demonstrated that miRNAs play a momentous role in oncogenesis
via regulating cell proliferation and apoptosis as oncogenes or tumour suppressors.
Expression signatures of miRNAs offer exciting opportunities for crafting cutting edge
strategies in the diagnosis, prognosis, and therapy of cancer. Since miRNAs can function
as either oncogenes or tumor suppressor genes in the tortuous route of oncogenesis,
the promise represented by using these small RNAs as therapeutic targets presents new
perspectives to the landscape of cancer therapy by either inhibiting or augmenting their
activity. This book devotes efforts to provide a broad framework for obtaining an in
depth understanding of the state-of-the-art knowledge on abnormalities of miRNAs
found to be associated with cancer pathogenesis and possible mechanisms underlying
the substantial roles played by miRNAs in cancer development and progression. Also, it
intends to pave the way for readers to gain novel insights into using miRNAs as cancer
b
io
markers and therapeutic platforms.
|
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| indexdate | 2024-07-10T01:03:31Z |
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| isbn | 3319037242 9783319037240 |
| language | English |
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| spelling | MicroRNAs key regulators of oncogenesis Sadegh Babashah, ed. Cham [u.a.] Springer 2014 XXVI, 433 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Krebs Medizin (DE-588)4073781-0 gnd rswk-swf miRNS (DE-588)7736808-3 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 s miRNS (DE-588)7736808-3 s DE-604 Babashah, Sadegh edt Erscheint auch als Online-Ausgabe 978-3-319-03725-7 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027159551&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027159551&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
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| subject_GND | (DE-588)4073781-0 (DE-588)7736808-3 |
| title | MicroRNAs key regulators of oncogenesis |
| title_auth | MicroRNAs key regulators of oncogenesis |
| title_exact_search | MicroRNAs key regulators of oncogenesis |
| title_full | MicroRNAs key regulators of oncogenesis Sadegh Babashah, ed. |
| title_fullStr | MicroRNAs key regulators of oncogenesis Sadegh Babashah, ed. |
| title_full_unstemmed | MicroRNAs key regulators of oncogenesis Sadegh Babashah, ed. |
| title_short | MicroRNAs |
| title_sort | micrornas key regulators of oncogenesis |
| title_sub | key regulators of oncogenesis |
| topic | Krebs Medizin (DE-588)4073781-0 gnd miRNS (DE-588)7736808-3 gnd |
| topic_facet | Krebs Medizin miRNS |
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