MicroRNAs in development and cancer:
MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of...
Saved in:
| Format: | Electronic eBook |
|---|---|
| Language: | English |
| Published: |
London
Imperial College Press
c2011
|
| Series: | Molecular medicine and medicinal chemistry
v. 1 |
| Subjects: | |
| Online Access: | FHN01 Volltext |
| Summary: | MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represent a paradigm shift in thinking about gene regulation during development and disease, and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer |
| Physical Description: | xv, 282 p. ill. (some col.) |
| ISBN: | 9781848163676 |
Staff View
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| id | DE-604.BV044633409 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T07:57:42Z |
| institution | BVB |
| isbn | 9781848163676 |
| language | English |
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| physical | xv, 282 p. ill. (some col.) |
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| publishDate | 2011 |
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| publisher | Imperial College Press |
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| series2 | Molecular medicine and medicinal chemistry |
| spelling | MicroRNAs in development and cancer editor, Frank J. Slack London Imperial College Press c2011 xv, 282 p. ill. (some col.) txt rdacontent c rdamedia cr rdacarrier Molecular medicine and medicinal chemistry v. 1 MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represent a paradigm shift in thinking about gene regulation during development and disease, and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer Cancer Small interfering RNA. Krebszelle (DE-588)4128704-6 gnd rswk-swf miRNS (DE-588)7736808-3 gnd rswk-swf Krebszelle (DE-588)4128704-6 s miRNS (DE-588)7736808-3 s 1\p DE-604 Slack, Frank J. Sonstige oth Erscheint auch als Druck-Ausgabe 1848163665 Erscheint auch als Druck-Ausgabe 9781848163669 http://www.worldscientific.com/worldscibooks/10.1142/P630#t=toc Verlag URL des Erstveroeffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | MicroRNAs in development and cancer Cancer Small interfering RNA. Krebszelle (DE-588)4128704-6 gnd miRNS (DE-588)7736808-3 gnd |
| subject_GND | (DE-588)4128704-6 (DE-588)7736808-3 |
| title | MicroRNAs in development and cancer |
| title_auth | MicroRNAs in development and cancer |
| title_exact_search | MicroRNAs in development and cancer |
| title_full | MicroRNAs in development and cancer editor, Frank J. Slack |
| title_fullStr | MicroRNAs in development and cancer editor, Frank J. Slack |
| title_full_unstemmed | MicroRNAs in development and cancer editor, Frank J. Slack |
| title_short | MicroRNAs in development and cancer |
| title_sort | micrornas in development and cancer |
| topic | Cancer Small interfering RNA. Krebszelle (DE-588)4128704-6 gnd miRNS (DE-588)7736808-3 gnd |
| topic_facet | Cancer Small interfering RNA. Krebszelle miRNS |
| url | http://www.worldscientific.com/worldscibooks/10.1142/P630#t=toc |
| work_keys_str_mv | AT slackfrankj micrornasindevelopmentandcancer |