Cystic Fibrosis Methods and Protocols:
Since the cloning of the cystic fibrosis transmembrane conductance regulator (CFTR) nearly a decade ago, cystic fibrosis researchers, clinicians, and patients have come to rely increasingly on a diverse array of fundamental techniques to understand the molecular basis of this complex disease. Cystic...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2002
|
| Schriftenreihe: | Methods in Molecular Medicine™
70 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Since the cloning of the cystic fibrosis transmembrane conductance regulator (CFTR) nearly a decade ago, cystic fibrosis researchers, clinicians, and patients have come to rely increasingly on a diverse array of fundamental techniques to understand the molecular basis of this complex disease. Cystic Fibrosis Methods and Protocols consolidates a broad range of detailed and readily reproducible in vitro, cellular, and whole animal laboratory protocols into an indispensable resource. From electrophysiology and cell biology, to animal models and gene therapy, this comprehensive set of methods provides the step-by-step instructions needed for investigators to incorporate new approaches into their research programs. Specific protocols describe new techniques for diagnosis, in vitro methods for the expression and functional analysis of CFTR, novel biochemical and cellular systems to determine how mutations subvert CFTR function, and in vivo protocols to examine how CFTR dysfunction produces multisystem pathology in human and animal models. Comprehensive, multidisciplinary, and highly practical, Cystic Fibrosis Methods and Protocols makes accessible to today's cystic fibrosis investigator the powerful new scientific techniques required to investigate the basic science of the disease and to translate this into effective clinical solutions |
| Beschreibung: | 1 Online-Ressource (XVI, 615 p) |
| ISBN: | 9781592591879 |
| DOI: | 10.1385/1592591876 |
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| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:05:34Z |
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| isbn | 9781592591879 |
| language | English |
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| spelling | Cystic Fibrosis Methods and Protocols edited by William R. Skach Totowa, NJ Humana Press 2002 1 Online-Ressource (XVI, 615 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Medicine™ 70 Since the cloning of the cystic fibrosis transmembrane conductance regulator (CFTR) nearly a decade ago, cystic fibrosis researchers, clinicians, and patients have come to rely increasingly on a diverse array of fundamental techniques to understand the molecular basis of this complex disease. Cystic Fibrosis Methods and Protocols consolidates a broad range of detailed and readily reproducible in vitro, cellular, and whole animal laboratory protocols into an indispensable resource. From electrophysiology and cell biology, to animal models and gene therapy, this comprehensive set of methods provides the step-by-step instructions needed for investigators to incorporate new approaches into their research programs. Specific protocols describe new techniques for diagnosis, in vitro methods for the expression and functional analysis of CFTR, novel biochemical and cellular systems to determine how mutations subvert CFTR function, and in vivo protocols to examine how CFTR dysfunction produces multisystem pathology in human and animal models. Comprehensive, multidisciplinary, and highly practical, Cystic Fibrosis Methods and Protocols makes accessible to today's cystic fibrosis investigator the powerful new scientific techniques required to investigate the basic science of the disease and to translate this into effective clinical solutions Medicine & Public Health Pneumology/Respiratory System Medicine Respiratory organs / Diseases Mukoviszidose (DE-588)4040669-6 gnd rswk-swf Molekulare Medizin (DE-588)4543844-4 gnd rswk-swf Mukoviszidose (DE-588)4040669-6 s Molekulare Medizin (DE-588)4543844-4 s DE-604 Skach, William R. edt Erscheint auch als Druck-Ausgabe 9780896038974 https://doi.org/10.1385/1592591876 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Cystic Fibrosis Methods and Protocols Medicine & Public Health Pneumology/Respiratory System Medicine Respiratory organs / Diseases Mukoviszidose (DE-588)4040669-6 gnd Molekulare Medizin (DE-588)4543844-4 gnd |
| subject_GND | (DE-588)4040669-6 (DE-588)4543844-4 |
| title | Cystic Fibrosis Methods and Protocols |
| title_auth | Cystic Fibrosis Methods and Protocols |
| title_exact_search | Cystic Fibrosis Methods and Protocols |
| title_full | Cystic Fibrosis Methods and Protocols edited by William R. Skach |
| title_fullStr | Cystic Fibrosis Methods and Protocols edited by William R. Skach |
| title_full_unstemmed | Cystic Fibrosis Methods and Protocols edited by William R. Skach |
| title_short | Cystic Fibrosis Methods and Protocols |
| title_sort | cystic fibrosis methods and protocols |
| topic | Medicine & Public Health Pneumology/Respiratory System Medicine Respiratory organs / Diseases Mukoviszidose (DE-588)4040669-6 gnd Molekulare Medizin (DE-588)4543844-4 gnd |
| topic_facet | Medicine & Public Health Pneumology/Respiratory System Medicine Respiratory organs / Diseases Mukoviszidose Molekulare Medizin |
| url | https://doi.org/10.1385/1592591876 |
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