Hepatitis C Virus-Host Interactions and Therapeutics:
The burden of hepatitis C virus (HCV) infection on the public health care system continues to remain significant despite the remarkable progress made in HCV therapeutics in the recent past. There are now almost a dozen oral interferon-free direct-acting antivirals available for the treatment of hepa...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Weitere Verfasser: | |
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Alexandria :
Bentham Science Publishers,
2023.
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | The burden of hepatitis C virus (HCV) infection on the public health care system continues to remain significant despite the remarkable progress made in HCV therapeutics in the recent past. There are now almost a dozen oral interferon-free direct-acting antivirals available for the treatment of hepatitis C virus infection. Despite advances in the treatment of HCV, therapeutic gaps remain that are yet to be fully explored. Researchers and scientists still striv. |
| Beschreibung: | Description based upon print version of record. Immune Responses and Immunopathology of Acute and Chronic Hepatitis C Virus Infection |
| Beschreibung: | 1 online resource (450 p.) |
| ISBN: | 9815123432 9789815123432 |
Internformat
MARC
| LEADER | 00000cam a2200000Mu 4500 | ||
|---|---|---|---|
| 001 | ZDB-4-EBA-on1370493352 | ||
| 003 | OCoLC | ||
| 005 | 20241004212047.0 | ||
| 006 | m o d | ||
| 007 | cr cnu|||||||| | ||
| 008 | 230225s2023 xx o ||| 0 eng d | ||
| 040 | |a EBLCP |b eng |c EBLCP |d N$T |d OCLCO | ||
| 066 | |c (S | ||
| 020 | |a 9815123432 | ||
| 020 | |a 9789815123432 |q (electronic bk.) | ||
| 035 | |a (OCoLC)1370493352 | ||
| 050 | 4 | |a QR201.H46 | |
| 082 | 7 | |a 616.3623 |2 23/eng/20230607 | |
| 049 | |a MAIN | ||
| 100 | 1 | |a Shahid, Imran. | |
| 245 | 1 | 0 | |a Hepatitis C Virus-Host Interactions and Therapeutics |h [electronic resource]. |
| 260 | |a Alexandria : |b Bentham Science Publishers, |c 2023. | ||
| 300 | |a 1 online resource (450 p.) | ||
| 500 | |a Description based upon print version of record. | ||
| 505 | 0 | |6 880-01 |a Cover -- Title -- Copyright -- End User License Agreement -- Contents -- Foreword -- Preface -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENT -- Dedication -- HCV-Host Interactions: A Plethora of Genes and their Intricate Interplay Part 1: Virus Specific Factors -- INTRODUCTION -- Hepatitis C Virus Taxonomy -- HCV: Route of Transmission -- HCV Genome Organization -- HCV MOLECULAR BIOLOGY -- HCV MOLECULAR VIROLOGY -- HEPATITIS C PROTEINS IN MOLECULAR PATHOGENESIS OF INFECTION -- 5' Untranslated Region (5' UTR) -- HCV Antigen (Core -- C) Protein | |
| 505 | 8 | |a HCV Core Protein Morphology -- HCV Core Protein and Hepatic Steatosis -- HCV Core Protein and Hepatocarcinogenesis -- HCV Core Protein and Insulin Resistance (IR) -- HCV Envelope Glycoproteins (E1 and E2) -- HCV E1 and E2 Morphology -- HVR1 of E2 Glycoprotein Modulates the Immune System -- HCV NONSTRUCTURAL PROTEINS AND THEIR ROLE IN HEPATITIS C PATHOGENESIS -- NS2 Metalloprotease -- NS3/4A Serine Protease/Helicase -- NS4B -- NS5A: An Interferon Resistance Protein -- NS5B: RNA Dependent RNA Polymerase (RdRp) -- 3' UTR -- CONCLUSIONS -- REFERENCES | |
| 505 | 8 | |a HCV-Host Interactions: Interplay Part 2: Host Related Determinants and Intracellular Signaling -- INTRODUCTION -- CERTAIN HOST SPECIFIC FACTORS ARE VITAL FOR HCV REPLICATION -- PPP2R5D (Protein Phosphatase 2 Regulatory Subunit B'Delta) Protein -- Micro RNAs (miRNA) -- miR-122: A Key Regulator of HCV Replication in Hepatocytes -- miR-135a Drives Chronic Hepatitis C Infection to HCC -- Cytokines Gene Polymorphisms in Chronic Hepatitis C Patients -- The Importance of Cytokines against Viral Infections -- Cytokine Gene Polymorphism for IL-10 -- Cytokine Gene Polymorphism for IL-13 | |
| 500 | |a Immune Responses and Immunopathology of Acute and Chronic Hepatitis C Virus Infection | ||
| 520 | |a The burden of hepatitis C virus (HCV) infection on the public health care system continues to remain significant despite the remarkable progress made in HCV therapeutics in the recent past. There are now almost a dozen oral interferon-free direct-acting antivirals available for the treatment of hepatitis C virus infection. Despite advances in the treatment of HCV, therapeutic gaps remain that are yet to be fully explored. Researchers and scientists still striv. | ||
| 650 | 0 | |a Hepatitis C virus |x Treatment. | |
| 650 | 6 | |a Virus de l'hépatite C |x Traitement. | |
| 700 | 1 | |a Jabeen, Qaiser. | |
| 776 | 0 | 8 | |i Print version: |a Shahid, Imran |t Hepatitis C Virus-Host Interactions and Therapeutics: Current Insights and Future Perspectives |d Alexandria : Bentham Science Publishers,c2023 |z 9789815123449 |
| 856 | 4 | 0 | |l FWS01 |p ZDB-4-EBA |q FWS_PDA_EBA |u https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3541992 |3 Volltext |
| 880 | 8 | |6 505-00/(S |a Gene Polymorphisms of Tumor Necrosis Factor-alpha (TNF-α) -- Role of Cytokine Storm in HBV Reactivation in HBV/HCV Coinfections -- Genetic Polymorphism in Host Genetic Factors of HIV-1/HCV Coinfected Patients Progress Toward Advanced Hepatic Fibrosis -- Genetic Polymorphisms of Interferon Lambda (IFNL 3/4) Genes in HCV Patients and its Clinical Significance -- DIFFERENTIAL EXPRESSION OF HOST CELLS LIPID METABOLISM REGULATORS IMPACT HEPATITIS C INFECTION PROGRESSION -- ANGPTL-3 and -4: Potent Regulators of Lipid Metabolism in Hepatocytes | |
| 880 | 8 | |6 505-01/(S |a ANGPTLs Linked to HCV Induced Hepatic Fibrosis and Tumorigenesis -- ANGPTL Expression in Various Stages of Hepatic Fibrosis -- ANGPTL-3/4 Interacts With TGF-β to Promote Hepatic Fibrosis and Cirrhosis -- VITAMIN D AND HCV INDUCED HEPATOCELLULAR CARCINOMA -- INTRACELLULAR SIGNALING MODULATION IN HEPATITIS C INFECTION -- TLR Activation and their Implications in HCV Molecular Pathogenesis -- TNF/TNF Receptor Activation in CHC Patients -- FAS/FASL Activation in CHC Patients -- NF-ƙB Cell Signaling and HCV Progression -- CONCLUSIONS -- REFERENCES | |
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL30377306 | ||
| 938 | |a EBSCOhost |b EBSC |n 3541992 | ||
| 994 | |a 92 |b GEBAY | ||
| 912 | |a ZDB-4-EBA | ||
| 049 | |a DE-863 | ||
Datensatz im Suchindex
| DE-BY-FWS_katkey | ZDB-4-EBA-on1370493352 |
|---|---|
| _version_ | 1816882568522366976 |
| adam_text | |
| any_adam_object | |
| author | Shahid, Imran |
| author2 | Jabeen, Qaiser |
| author2_role | |
| author2_variant | q j qj |
| author_facet | Shahid, Imran Jabeen, Qaiser |
| author_role | |
| author_sort | Shahid, Imran |
| author_variant | i s is |
| building | Verbundindex |
| bvnumber | localFWS |
| callnumber-first | Q - Science |
| callnumber-label | QR201 |
| callnumber-raw | QR201.H46 |
| callnumber-search | QR201.H46 |
| callnumber-sort | QR 3201 H46 |
| callnumber-subject | QR - Microbiology |
| collection | ZDB-4-EBA |
| contents | Cover -- Title -- Copyright -- End User License Agreement -- Contents -- Foreword -- Preface -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENT -- Dedication -- HCV-Host Interactions: A Plethora of Genes and their Intricate Interplay Part 1: Virus Specific Factors -- INTRODUCTION -- Hepatitis C Virus Taxonomy -- HCV: Route of Transmission -- HCV Genome Organization -- HCV MOLECULAR BIOLOGY -- HCV MOLECULAR VIROLOGY -- HEPATITIS C PROTEINS IN MOLECULAR PATHOGENESIS OF INFECTION -- 5' Untranslated Region (5' UTR) -- HCV Antigen (Core -- C) Protein HCV Core Protein Morphology -- HCV Core Protein and Hepatic Steatosis -- HCV Core Protein and Hepatocarcinogenesis -- HCV Core Protein and Insulin Resistance (IR) -- HCV Envelope Glycoproteins (E1 and E2) -- HCV E1 and E2 Morphology -- HVR1 of E2 Glycoprotein Modulates the Immune System -- HCV NONSTRUCTURAL PROTEINS AND THEIR ROLE IN HEPATITIS C PATHOGENESIS -- NS2 Metalloprotease -- NS3/4A Serine Protease/Helicase -- NS4B -- NS5A: An Interferon Resistance Protein -- NS5B: RNA Dependent RNA Polymerase (RdRp) -- 3' UTR -- CONCLUSIONS -- REFERENCES HCV-Host Interactions: Interplay Part 2: Host Related Determinants and Intracellular Signaling -- INTRODUCTION -- CERTAIN HOST SPECIFIC FACTORS ARE VITAL FOR HCV REPLICATION -- PPP2R5D (Protein Phosphatase 2 Regulatory Subunit B'Delta) Protein -- Micro RNAs (miRNA) -- miR-122: A Key Regulator of HCV Replication in Hepatocytes -- miR-135a Drives Chronic Hepatitis C Infection to HCC -- Cytokines Gene Polymorphisms in Chronic Hepatitis C Patients -- The Importance of Cytokines against Viral Infections -- Cytokine Gene Polymorphism for IL-10 -- Cytokine Gene Polymorphism for IL-13 |
| ctrlnum | (OCoLC)1370493352 |
| dewey-full | 616.3623 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.3623 |
| dewey-search | 616.3623 |
| dewey-sort | 3616.3623 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>04823cam a2200433Mu 4500</leader><controlfield tag="001">ZDB-4-EBA-on1370493352</controlfield><controlfield tag="003">OCoLC</controlfield><controlfield tag="005">20241004212047.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr cnu||||||||</controlfield><controlfield tag="008">230225s2023 xx o ||| 0 eng d</controlfield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">EBLCP</subfield><subfield code="b">eng</subfield><subfield code="c">EBLCP</subfield><subfield code="d">N$T</subfield><subfield code="d">OCLCO</subfield></datafield><datafield tag="066" ind1=" " ind2=" "><subfield code="c">(S</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9815123432</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9789815123432</subfield><subfield code="q">(electronic bk.)</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1370493352</subfield></datafield><datafield tag="050" ind1=" " ind2="4"><subfield code="a">QR201.H46</subfield></datafield><datafield tag="082" ind1="7" ind2=" "><subfield code="a">616.3623</subfield><subfield code="2">23/eng/20230607</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">MAIN</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Shahid, Imran.</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Hepatitis C Virus-Host Interactions and Therapeutics</subfield><subfield code="h">[electronic resource].</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="a">Alexandria :</subfield><subfield code="b">Bentham Science Publishers,</subfield><subfield code="c">2023.</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource (450 p.)</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Description based upon print version of record.</subfield></datafield><datafield tag="505" ind1="0" ind2=" "><subfield code="6">880-01</subfield><subfield code="a">Cover -- Title -- Copyright -- End User License Agreement -- Contents -- Foreword -- Preface -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENT -- Dedication -- HCV-Host Interactions: A Plethora of Genes and their Intricate Interplay Part 1: Virus Specific Factors -- INTRODUCTION -- Hepatitis C Virus Taxonomy -- HCV: Route of Transmission -- HCV Genome Organization -- HCV MOLECULAR BIOLOGY -- HCV MOLECULAR VIROLOGY -- HEPATITIS C PROTEINS IN MOLECULAR PATHOGENESIS OF INFECTION -- 5' Untranslated Region (5' UTR) -- HCV Antigen (Core -- C) Protein</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">HCV Core Protein Morphology -- HCV Core Protein and Hepatic Steatosis -- HCV Core Protein and Hepatocarcinogenesis -- HCV Core Protein and Insulin Resistance (IR) -- HCV Envelope Glycoproteins (E1 and E2) -- HCV E1 and E2 Morphology -- HVR1 of E2 Glycoprotein Modulates the Immune System -- HCV NONSTRUCTURAL PROTEINS AND THEIR ROLE IN HEPATITIS C PATHOGENESIS -- NS2 Metalloprotease -- NS3/4A Serine Protease/Helicase -- NS4B -- NS5A: An Interferon Resistance Protein -- NS5B: RNA Dependent RNA Polymerase (RdRp) -- 3' UTR -- CONCLUSIONS -- REFERENCES</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">HCV-Host Interactions: Interplay Part 2: Host Related Determinants and Intracellular Signaling -- INTRODUCTION -- CERTAIN HOST SPECIFIC FACTORS ARE VITAL FOR HCV REPLICATION -- PPP2R5D (Protein Phosphatase 2 Regulatory Subunit B'Delta) Protein -- Micro RNAs (miRNA) -- miR-122: A Key Regulator of HCV Replication in Hepatocytes -- miR-135a Drives Chronic Hepatitis C Infection to HCC -- Cytokines Gene Polymorphisms in Chronic Hepatitis C Patients -- The Importance of Cytokines against Viral Infections -- Cytokine Gene Polymorphism for IL-10 -- Cytokine Gene Polymorphism for IL-13</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Immune Responses and Immunopathology of Acute and Chronic Hepatitis C Virus Infection</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The burden of hepatitis C virus (HCV) infection on the public health care system continues to remain significant despite the remarkable progress made in HCV therapeutics in the recent past. There are now almost a dozen oral interferon-free direct-acting antivirals available for the treatment of hepatitis C virus infection. Despite advances in the treatment of HCV, therapeutic gaps remain that are yet to be fully explored. Researchers and scientists still striv.</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">Hepatitis C virus</subfield><subfield code="x">Treatment.</subfield></datafield><datafield tag="650" ind1=" " ind2="6"><subfield code="a">Virus de l'hépatite C</subfield><subfield code="x">Traitement.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Jabeen, Qaiser.</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Print version:</subfield><subfield code="a">Shahid, Imran</subfield><subfield code="t">Hepatitis C Virus-Host Interactions and Therapeutics: Current Insights and Future Perspectives</subfield><subfield code="d">Alexandria : Bentham Science Publishers,c2023</subfield><subfield code="z">9789815123449</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="l">FWS01</subfield><subfield code="p">ZDB-4-EBA</subfield><subfield code="q">FWS_PDA_EBA</subfield><subfield code="u">https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3541992</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="880" ind1="8" ind2=" "><subfield code="6">505-00/(S</subfield><subfield code="a">Gene Polymorphisms of Tumor Necrosis Factor-alpha (TNF-α) -- Role of Cytokine Storm in HBV Reactivation in HBV/HCV Coinfections -- Genetic Polymorphism in Host Genetic Factors of HIV-1/HCV Coinfected Patients Progress Toward Advanced Hepatic Fibrosis -- Genetic Polymorphisms of Interferon Lambda (IFNL 3/4) Genes in HCV Patients and its Clinical Significance -- DIFFERENTIAL EXPRESSION OF HOST CELLS LIPID METABOLISM REGULATORS IMPACT HEPATITIS C INFECTION PROGRESSION -- ANGPTL-3 and -4: Potent Regulators of Lipid Metabolism in Hepatocytes</subfield></datafield><datafield tag="880" ind1="8" ind2=" "><subfield code="6">505-01/(S</subfield><subfield code="a">ANGPTLs Linked to HCV Induced Hepatic Fibrosis and Tumorigenesis -- ANGPTL Expression in Various Stages of Hepatic Fibrosis -- ANGPTL-3/4 Interacts With TGF-β to Promote Hepatic Fibrosis and Cirrhosis -- VITAMIN D AND HCV INDUCED HEPATOCELLULAR CARCINOMA -- INTRACELLULAR SIGNALING MODULATION IN HEPATITIS C INFECTION -- TLR Activation and their Implications in HCV Molecular Pathogenesis -- TNF/TNF Receptor Activation in CHC Patients -- FAS/FASL Activation in CHC Patients -- NF-ƙB Cell Signaling and HCV Progression -- CONCLUSIONS -- REFERENCES</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">ProQuest Ebook Central</subfield><subfield code="b">EBLB</subfield><subfield code="n">EBL30377306</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">EBSCOhost</subfield><subfield code="b">EBSC</subfield><subfield code="n">3541992</subfield></datafield><datafield tag="994" ind1=" " ind2=" "><subfield code="a">92</subfield><subfield code="b">GEBAY</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-4-EBA</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-863</subfield></datafield></record></collection> |
| id | ZDB-4-EBA-on1370493352 |
| illustrated | Not Illustrated |
| indexdate | 2024-11-27T13:30:41Z |
| institution | BVB |
| isbn | 9815123432 9789815123432 |
| language | English |
| oclc_num | 1370493352 |
| open_access_boolean | |
| owner | MAIN DE-863 DE-BY-FWS |
| owner_facet | MAIN DE-863 DE-BY-FWS |
| physical | 1 online resource (450 p.) |
| psigel | ZDB-4-EBA |
| publishDate | 2023 |
| publishDateSearch | 2023 |
| publishDateSort | 2023 |
| publisher | Bentham Science Publishers, |
| record_format | marc |
| spelling | Shahid, Imran. Hepatitis C Virus-Host Interactions and Therapeutics [electronic resource]. Alexandria : Bentham Science Publishers, 2023. 1 online resource (450 p.) Description based upon print version of record. 880-01 Cover -- Title -- Copyright -- End User License Agreement -- Contents -- Foreword -- Preface -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENT -- Dedication -- HCV-Host Interactions: A Plethora of Genes and their Intricate Interplay Part 1: Virus Specific Factors -- INTRODUCTION -- Hepatitis C Virus Taxonomy -- HCV: Route of Transmission -- HCV Genome Organization -- HCV MOLECULAR BIOLOGY -- HCV MOLECULAR VIROLOGY -- HEPATITIS C PROTEINS IN MOLECULAR PATHOGENESIS OF INFECTION -- 5' Untranslated Region (5' UTR) -- HCV Antigen (Core -- C) Protein HCV Core Protein Morphology -- HCV Core Protein and Hepatic Steatosis -- HCV Core Protein and Hepatocarcinogenesis -- HCV Core Protein and Insulin Resistance (IR) -- HCV Envelope Glycoproteins (E1 and E2) -- HCV E1 and E2 Morphology -- HVR1 of E2 Glycoprotein Modulates the Immune System -- HCV NONSTRUCTURAL PROTEINS AND THEIR ROLE IN HEPATITIS C PATHOGENESIS -- NS2 Metalloprotease -- NS3/4A Serine Protease/Helicase -- NS4B -- NS5A: An Interferon Resistance Protein -- NS5B: RNA Dependent RNA Polymerase (RdRp) -- 3' UTR -- CONCLUSIONS -- REFERENCES HCV-Host Interactions: Interplay Part 2: Host Related Determinants and Intracellular Signaling -- INTRODUCTION -- CERTAIN HOST SPECIFIC FACTORS ARE VITAL FOR HCV REPLICATION -- PPP2R5D (Protein Phosphatase 2 Regulatory Subunit B'Delta) Protein -- Micro RNAs (miRNA) -- miR-122: A Key Regulator of HCV Replication in Hepatocytes -- miR-135a Drives Chronic Hepatitis C Infection to HCC -- Cytokines Gene Polymorphisms in Chronic Hepatitis C Patients -- The Importance of Cytokines against Viral Infections -- Cytokine Gene Polymorphism for IL-10 -- Cytokine Gene Polymorphism for IL-13 Immune Responses and Immunopathology of Acute and Chronic Hepatitis C Virus Infection The burden of hepatitis C virus (HCV) infection on the public health care system continues to remain significant despite the remarkable progress made in HCV therapeutics in the recent past. There are now almost a dozen oral interferon-free direct-acting antivirals available for the treatment of hepatitis C virus infection. Despite advances in the treatment of HCV, therapeutic gaps remain that are yet to be fully explored. Researchers and scientists still striv. Hepatitis C virus Treatment. Virus de l'hépatite C Traitement. Jabeen, Qaiser. Print version: Shahid, Imran Hepatitis C Virus-Host Interactions and Therapeutics: Current Insights and Future Perspectives Alexandria : Bentham Science Publishers,c2023 9789815123449 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3541992 Volltext 505-00/(S Gene Polymorphisms of Tumor Necrosis Factor-alpha (TNF-α) -- Role of Cytokine Storm in HBV Reactivation in HBV/HCV Coinfections -- Genetic Polymorphism in Host Genetic Factors of HIV-1/HCV Coinfected Patients Progress Toward Advanced Hepatic Fibrosis -- Genetic Polymorphisms of Interferon Lambda (IFNL 3/4) Genes in HCV Patients and its Clinical Significance -- DIFFERENTIAL EXPRESSION OF HOST CELLS LIPID METABOLISM REGULATORS IMPACT HEPATITIS C INFECTION PROGRESSION -- ANGPTL-3 and -4: Potent Regulators of Lipid Metabolism in Hepatocytes 505-01/(S ANGPTLs Linked to HCV Induced Hepatic Fibrosis and Tumorigenesis -- ANGPTL Expression in Various Stages of Hepatic Fibrosis -- ANGPTL-3/4 Interacts With TGF-β to Promote Hepatic Fibrosis and Cirrhosis -- VITAMIN D AND HCV INDUCED HEPATOCELLULAR CARCINOMA -- INTRACELLULAR SIGNALING MODULATION IN HEPATITIS C INFECTION -- TLR Activation and their Implications in HCV Molecular Pathogenesis -- TNF/TNF Receptor Activation in CHC Patients -- FAS/FASL Activation in CHC Patients -- NF-ƙB Cell Signaling and HCV Progression -- CONCLUSIONS -- REFERENCES |
| spellingShingle | Shahid, Imran Hepatitis C Virus-Host Interactions and Therapeutics Cover -- Title -- Copyright -- End User License Agreement -- Contents -- Foreword -- Preface -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENT -- Dedication -- HCV-Host Interactions: A Plethora of Genes and their Intricate Interplay Part 1: Virus Specific Factors -- INTRODUCTION -- Hepatitis C Virus Taxonomy -- HCV: Route of Transmission -- HCV Genome Organization -- HCV MOLECULAR BIOLOGY -- HCV MOLECULAR VIROLOGY -- HEPATITIS C PROTEINS IN MOLECULAR PATHOGENESIS OF INFECTION -- 5' Untranslated Region (5' UTR) -- HCV Antigen (Core -- C) Protein HCV Core Protein Morphology -- HCV Core Protein and Hepatic Steatosis -- HCV Core Protein and Hepatocarcinogenesis -- HCV Core Protein and Insulin Resistance (IR) -- HCV Envelope Glycoproteins (E1 and E2) -- HCV E1 and E2 Morphology -- HVR1 of E2 Glycoprotein Modulates the Immune System -- HCV NONSTRUCTURAL PROTEINS AND THEIR ROLE IN HEPATITIS C PATHOGENESIS -- NS2 Metalloprotease -- NS3/4A Serine Protease/Helicase -- NS4B -- NS5A: An Interferon Resistance Protein -- NS5B: RNA Dependent RNA Polymerase (RdRp) -- 3' UTR -- CONCLUSIONS -- REFERENCES HCV-Host Interactions: Interplay Part 2: Host Related Determinants and Intracellular Signaling -- INTRODUCTION -- CERTAIN HOST SPECIFIC FACTORS ARE VITAL FOR HCV REPLICATION -- PPP2R5D (Protein Phosphatase 2 Regulatory Subunit B'Delta) Protein -- Micro RNAs (miRNA) -- miR-122: A Key Regulator of HCV Replication in Hepatocytes -- miR-135a Drives Chronic Hepatitis C Infection to HCC -- Cytokines Gene Polymorphisms in Chronic Hepatitis C Patients -- The Importance of Cytokines against Viral Infections -- Cytokine Gene Polymorphism for IL-10 -- Cytokine Gene Polymorphism for IL-13 Hepatitis C virus Treatment. Virus de l'hépatite C Traitement. |
| title | Hepatitis C Virus-Host Interactions and Therapeutics |
| title_auth | Hepatitis C Virus-Host Interactions and Therapeutics |
| title_exact_search | Hepatitis C Virus-Host Interactions and Therapeutics |
| title_full | Hepatitis C Virus-Host Interactions and Therapeutics [electronic resource]. |
| title_fullStr | Hepatitis C Virus-Host Interactions and Therapeutics [electronic resource]. |
| title_full_unstemmed | Hepatitis C Virus-Host Interactions and Therapeutics [electronic resource]. |
| title_short | Hepatitis C Virus-Host Interactions and Therapeutics |
| title_sort | hepatitis c virus host interactions and therapeutics |
| topic | Hepatitis C virus Treatment. Virus de l'hépatite C Traitement. |
| topic_facet | Hepatitis C virus Treatment. Virus de l'hépatite C Traitement. |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3541992 |
| work_keys_str_mv | AT shahidimran hepatitiscvirushostinteractionsandtherapeutics AT jabeenqaiser hepatitiscvirushostinteractionsandtherapeutics |