Biomaterial Based Approaches to Study the Tumour Microenvironment /:
This book provides an introduction to the rich chemical, topographical, and mechanical cues in the tumour microenvironment and then introduces readers to bioengineering strategies.
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge :
Royal Society of Chemistry,
2022.
|
| Schriftenreihe: | Biomaterials science series.
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | This book provides an introduction to the rich chemical, topographical, and mechanical cues in the tumour microenvironment and then introduces readers to bioengineering strategies. |
| Beschreibung: | 1 online resource (487 p.). |
| ISBN: | 9781839166013 1839166010 9781839166020 1839166029 |
Internformat
MARC
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| 245 | 0 | 0 | |a Biomaterial Based Approaches to Study the Tumour Microenvironment / |c editors: Jessica O. Winter, Shreyas Rao. |
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| 505 | 0 | |a Cover -- Contents -- Preface -- Chapter 1 Tissue Engineering Models for Cancer Pathology -- 1.1 Introduction -- 1.2 Historical Timeline -- 1.3 Content Organization -- 1.4 Conclusions and Future Outlook -- Acknowledgements -- References -- Chapter 2 Introduction to the Tumor Microenvironment -- 2.1 Cancer -- 2.2 The Tumor Microenvironment -- 2.3 The Tumor and its Microenvironment -- Principles -- 2.4 The Phenotype of TME-residing Cells (Cancer andNon-cancerous Cells Alike) is Shaped by Reciprocal Cues -- 2.4.1 Cell to Cell Signaling -- 2.4.2 Acellular Signaling | |
| 505 | 8 | |a 2.5 Target Cancer-TME Interactions for Cancer Therapy -- Acknowledgements -- References -- Chapter 3 Mimicking Fibrous Topographical Features of the Tumor Microenvironment -- 3.1 The Fibrous Extracellular Matrix in Tumors -- 3.2 Strategies to Mimic Fibrous ECM -- 3.3 Capturing the Interactions in the Tumor Microenvironment -- 3.3.1 Protrusions in Cancer Cells -- 3.3.2 Cancer Cell Migration -- 3.3.3 Forces Exerted by Cancer Cells -- 3.4 Concluding Remarks -- Acknowledgements -- References -- Chapter 4 Mimicking Mechanical Features of the Tumor Microenvironment | |
| 505 | 8 | |a 4.1 Introduction to the Complex Nature of the Cancer Microenvironment -- 4.2 Impact of the Tumor MicroenvironmentalComponents or Constituents on Mechanics (Three Ways) -- 4.3 Microenvironmental Embedded Cells Impact Mechanics -- 4.3.1 Endothelial Cells Including Tumor Endothelial Cells and Pericytes -- 4.3.2 Cancer Associated Fibroblasts (CAFs) -- 4.3.3 Mast Cells in Tumors -- 4.3.4 Tumor Associated Macrophages (TAMs) -- 4.3.5 Immune Cells of the Innate and Adaptive Immune System -- 4.3.6 Cancer-associated Eosinophiles -- 4.3.7 Cancer-associated Neutrophiles | |
| 505 | 8 | |a 4.4 Dimensionality of Cell Culture Systems and Mechanics -- 4.5 How Can the Mechanics of Tumor Microenvironments be Mimicked? -- 4.6 Effects of Native and Synthetic Microenvironments on Matrix and Cancer Cell Mechanics -- 4.6.1 Synthetic Matrices -- 4.6.2 Combined Native and Synthetic Matrices -- 4.6.3 Interpenetrating Networks -- 4.6.4 Microstructured Gels -- 4.7 Multicomponent Tumor Microenvironment Models -- 4.8 How do Mechanical Phenotypes of TumorMicroenvironments Contribute to Malignant Cancer Progression? -- 4.9 Conclusion and Outlook -- References | |
| 505 | 8 | |a Chapter 5 Mimicking Chemical Features of the Tumor Microenvironment -- 5.1 Introduction -- 5.2 Hallmarks of the Tumor Microenvironment -- 5.2.1 Components of the Tumor Microenvironment -- 5.3 Biomaterial Strategies to Mimic the Tumor Microenvironment -- 5.3.1 Natural Biomaterials -- 5.3.2 Synthetic Biomaterials -- 5.4 Recent Advances in Biomaterial Design for Cancer Research -- 5.5 Conclusion -- Disclosure Statement -- Abbreviations -- Acknowledgements -- References -- Chapter 6 Mimicking Multicellular Features of the Tumor Microenvironment -- 6.1 Introduction | |
| 505 | 8 | |a 6.1.1 Basic Concepts for Modelling the Tumour Microenvironment | |
| 520 | |a This book provides an introduction to the rich chemical, topographical, and mechanical cues in the tumour microenvironment and then introduces readers to bioengineering strategies. | ||
| 650 | 0 | |a Tumors. |0 http://id.loc.gov/authorities/subjects/sh85138553 | |
| 650 | 0 | |a Biomedical materials. |0 http://id.loc.gov/authorities/subjects/sh85014239 | |
| 650 | 2 | |a Neoplasms |0 https://id.nlm.nih.gov/mesh/D009369 | |
| 650 | 6 | |a Tumeurs. | |
| 650 | 6 | |a Biomatériaux. | |
| 650 | 7 | |a Biomedical materials |2 fast | |
| 650 | 7 | |a Tumors |2 fast | |
| 700 | 1 | |a Winter, Jessica |c (Chemical engineer) |1 https://id.oclc.org/worldcat/entity/E39PBJbWyG8q8pyVbcGbpGYtrq |0 http://id.loc.gov/authorities/names/no2017091276 | |
| 700 | 1 | |a Rao, Shreyas. | |
| 776 | 0 | 8 | |i Print version: |a Winter, Jessica O |t Biomaterial Based Approaches to Study the Tumour Microenvironment |d Cambridge : Royal Society of Chemistry,c2022 |z 9781839162848 |
| 830 | 0 | |a Biomaterials science series. |0 http://id.loc.gov/authorities/names/n2019180558 | |
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| contents | Cover -- Contents -- Preface -- Chapter 1 Tissue Engineering Models for Cancer Pathology -- 1.1 Introduction -- 1.2 Historical Timeline -- 1.3 Content Organization -- 1.4 Conclusions and Future Outlook -- Acknowledgements -- References -- Chapter 2 Introduction to the Tumor Microenvironment -- 2.1 Cancer -- 2.2 The Tumor Microenvironment -- 2.3 The Tumor and its Microenvironment -- Principles -- 2.4 The Phenotype of TME-residing Cells (Cancer andNon-cancerous Cells Alike) is Shaped by Reciprocal Cues -- 2.4.1 Cell to Cell Signaling -- 2.4.2 Acellular Signaling 2.5 Target Cancer-TME Interactions for Cancer Therapy -- Acknowledgements -- References -- Chapter 3 Mimicking Fibrous Topographical Features of the Tumor Microenvironment -- 3.1 The Fibrous Extracellular Matrix in Tumors -- 3.2 Strategies to Mimic Fibrous ECM -- 3.3 Capturing the Interactions in the Tumor Microenvironment -- 3.3.1 Protrusions in Cancer Cells -- 3.3.2 Cancer Cell Migration -- 3.3.3 Forces Exerted by Cancer Cells -- 3.4 Concluding Remarks -- Acknowledgements -- References -- Chapter 4 Mimicking Mechanical Features of the Tumor Microenvironment 4.1 Introduction to the Complex Nature of the Cancer Microenvironment -- 4.2 Impact of the Tumor MicroenvironmentalComponents or Constituents on Mechanics (Three Ways) -- 4.3 Microenvironmental Embedded Cells Impact Mechanics -- 4.3.1 Endothelial Cells Including Tumor Endothelial Cells and Pericytes -- 4.3.2 Cancer Associated Fibroblasts (CAFs) -- 4.3.3 Mast Cells in Tumors -- 4.3.4 Tumor Associated Macrophages (TAMs) -- 4.3.5 Immune Cells of the Innate and Adaptive Immune System -- 4.3.6 Cancer-associated Eosinophiles -- 4.3.7 Cancer-associated Neutrophiles 4.4 Dimensionality of Cell Culture Systems and Mechanics -- 4.5 How Can the Mechanics of Tumor Microenvironments be Mimicked? -- 4.6 Effects of Native and Synthetic Microenvironments on Matrix and Cancer Cell Mechanics -- 4.6.1 Synthetic Matrices -- 4.6.2 Combined Native and Synthetic Matrices -- 4.6.3 Interpenetrating Networks -- 4.6.4 Microstructured Gels -- 4.7 Multicomponent Tumor Microenvironment Models -- 4.8 How do Mechanical Phenotypes of TumorMicroenvironments Contribute to Malignant Cancer Progression? -- 4.9 Conclusion and Outlook -- References Chapter 5 Mimicking Chemical Features of the Tumor Microenvironment -- 5.1 Introduction -- 5.2 Hallmarks of the Tumor Microenvironment -- 5.2.1 Components of the Tumor Microenvironment -- 5.3 Biomaterial Strategies to Mimic the Tumor Microenvironment -- 5.3.1 Natural Biomaterials -- 5.3.2 Synthetic Biomaterials -- 5.4 Recent Advances in Biomaterial Design for Cancer Research -- 5.5 Conclusion -- Disclosure Statement -- Abbreviations -- Acknowledgements -- References -- Chapter 6 Mimicking Multicellular Features of the Tumor Microenvironment -- 6.1 Introduction 6.1.1 Basic Concepts for Modelling the Tumour Microenvironment |
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| id | ZDB-4-EBA-on1354209218 |
| illustrated | Not Illustrated |
| indexdate | 2024-11-27T13:30:40Z |
| institution | BVB |
| isbn | 9781839166013 1839166010 9781839166020 1839166029 |
| language | English |
| oclc_num | 1354209218 |
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| series | Biomaterials science series. |
| series2 | Biomaterials science series |
| spelling | Biomaterial Based Approaches to Study the Tumour Microenvironment / editors: Jessica O. Winter, Shreyas Rao. Cambridge : Royal Society of Chemistry, 2022. 1 online resource (487 p.). text txt rdacontent computer c rdamedia online resource cr rdacarrier Biomaterials science series Print version record. Cover -- Contents -- Preface -- Chapter 1 Tissue Engineering Models for Cancer Pathology -- 1.1 Introduction -- 1.2 Historical Timeline -- 1.3 Content Organization -- 1.4 Conclusions and Future Outlook -- Acknowledgements -- References -- Chapter 2 Introduction to the Tumor Microenvironment -- 2.1 Cancer -- 2.2 The Tumor Microenvironment -- 2.3 The Tumor and its Microenvironment -- Principles -- 2.4 The Phenotype of TME-residing Cells (Cancer andNon-cancerous Cells Alike) is Shaped by Reciprocal Cues -- 2.4.1 Cell to Cell Signaling -- 2.4.2 Acellular Signaling 2.5 Target Cancer-TME Interactions for Cancer Therapy -- Acknowledgements -- References -- Chapter 3 Mimicking Fibrous Topographical Features of the Tumor Microenvironment -- 3.1 The Fibrous Extracellular Matrix in Tumors -- 3.2 Strategies to Mimic Fibrous ECM -- 3.3 Capturing the Interactions in the Tumor Microenvironment -- 3.3.1 Protrusions in Cancer Cells -- 3.3.2 Cancer Cell Migration -- 3.3.3 Forces Exerted by Cancer Cells -- 3.4 Concluding Remarks -- Acknowledgements -- References -- Chapter 4 Mimicking Mechanical Features of the Tumor Microenvironment 4.1 Introduction to the Complex Nature of the Cancer Microenvironment -- 4.2 Impact of the Tumor MicroenvironmentalComponents or Constituents on Mechanics (Three Ways) -- 4.3 Microenvironmental Embedded Cells Impact Mechanics -- 4.3.1 Endothelial Cells Including Tumor Endothelial Cells and Pericytes -- 4.3.2 Cancer Associated Fibroblasts (CAFs) -- 4.3.3 Mast Cells in Tumors -- 4.3.4 Tumor Associated Macrophages (TAMs) -- 4.3.5 Immune Cells of the Innate and Adaptive Immune System -- 4.3.6 Cancer-associated Eosinophiles -- 4.3.7 Cancer-associated Neutrophiles 4.4 Dimensionality of Cell Culture Systems and Mechanics -- 4.5 How Can the Mechanics of Tumor Microenvironments be Mimicked? -- 4.6 Effects of Native and Synthetic Microenvironments on Matrix and Cancer Cell Mechanics -- 4.6.1 Synthetic Matrices -- 4.6.2 Combined Native and Synthetic Matrices -- 4.6.3 Interpenetrating Networks -- 4.6.4 Microstructured Gels -- 4.7 Multicomponent Tumor Microenvironment Models -- 4.8 How do Mechanical Phenotypes of TumorMicroenvironments Contribute to Malignant Cancer Progression? -- 4.9 Conclusion and Outlook -- References Chapter 5 Mimicking Chemical Features of the Tumor Microenvironment -- 5.1 Introduction -- 5.2 Hallmarks of the Tumor Microenvironment -- 5.2.1 Components of the Tumor Microenvironment -- 5.3 Biomaterial Strategies to Mimic the Tumor Microenvironment -- 5.3.1 Natural Biomaterials -- 5.3.2 Synthetic Biomaterials -- 5.4 Recent Advances in Biomaterial Design for Cancer Research -- 5.5 Conclusion -- Disclosure Statement -- Abbreviations -- Acknowledgements -- References -- Chapter 6 Mimicking Multicellular Features of the Tumor Microenvironment -- 6.1 Introduction 6.1.1 Basic Concepts for Modelling the Tumour Microenvironment This book provides an introduction to the rich chemical, topographical, and mechanical cues in the tumour microenvironment and then introduces readers to bioengineering strategies. Tumors. http://id.loc.gov/authorities/subjects/sh85138553 Biomedical materials. http://id.loc.gov/authorities/subjects/sh85014239 Neoplasms https://id.nlm.nih.gov/mesh/D009369 Tumeurs. Biomatériaux. Biomedical materials fast Tumors fast Winter, Jessica (Chemical engineer) https://id.oclc.org/worldcat/entity/E39PBJbWyG8q8pyVbcGbpGYtrq http://id.loc.gov/authorities/names/no2017091276 Rao, Shreyas. Print version: Winter, Jessica O Biomaterial Based Approaches to Study the Tumour Microenvironment Cambridge : Royal Society of Chemistry,c2022 9781839162848 Biomaterials science series. http://id.loc.gov/authorities/names/n2019180558 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3487865 Volltext |
| spellingShingle | Biomaterial Based Approaches to Study the Tumour Microenvironment / Biomaterials science series. Cover -- Contents -- Preface -- Chapter 1 Tissue Engineering Models for Cancer Pathology -- 1.1 Introduction -- 1.2 Historical Timeline -- 1.3 Content Organization -- 1.4 Conclusions and Future Outlook -- Acknowledgements -- References -- Chapter 2 Introduction to the Tumor Microenvironment -- 2.1 Cancer -- 2.2 The Tumor Microenvironment -- 2.3 The Tumor and its Microenvironment -- Principles -- 2.4 The Phenotype of TME-residing Cells (Cancer andNon-cancerous Cells Alike) is Shaped by Reciprocal Cues -- 2.4.1 Cell to Cell Signaling -- 2.4.2 Acellular Signaling 2.5 Target Cancer-TME Interactions for Cancer Therapy -- Acknowledgements -- References -- Chapter 3 Mimicking Fibrous Topographical Features of the Tumor Microenvironment -- 3.1 The Fibrous Extracellular Matrix in Tumors -- 3.2 Strategies to Mimic Fibrous ECM -- 3.3 Capturing the Interactions in the Tumor Microenvironment -- 3.3.1 Protrusions in Cancer Cells -- 3.3.2 Cancer Cell Migration -- 3.3.3 Forces Exerted by Cancer Cells -- 3.4 Concluding Remarks -- Acknowledgements -- References -- Chapter 4 Mimicking Mechanical Features of the Tumor Microenvironment 4.1 Introduction to the Complex Nature of the Cancer Microenvironment -- 4.2 Impact of the Tumor MicroenvironmentalComponents or Constituents on Mechanics (Three Ways) -- 4.3 Microenvironmental Embedded Cells Impact Mechanics -- 4.3.1 Endothelial Cells Including Tumor Endothelial Cells and Pericytes -- 4.3.2 Cancer Associated Fibroblasts (CAFs) -- 4.3.3 Mast Cells in Tumors -- 4.3.4 Tumor Associated Macrophages (TAMs) -- 4.3.5 Immune Cells of the Innate and Adaptive Immune System -- 4.3.6 Cancer-associated Eosinophiles -- 4.3.7 Cancer-associated Neutrophiles 4.4 Dimensionality of Cell Culture Systems and Mechanics -- 4.5 How Can the Mechanics of Tumor Microenvironments be Mimicked? -- 4.6 Effects of Native and Synthetic Microenvironments on Matrix and Cancer Cell Mechanics -- 4.6.1 Synthetic Matrices -- 4.6.2 Combined Native and Synthetic Matrices -- 4.6.3 Interpenetrating Networks -- 4.6.4 Microstructured Gels -- 4.7 Multicomponent Tumor Microenvironment Models -- 4.8 How do Mechanical Phenotypes of TumorMicroenvironments Contribute to Malignant Cancer Progression? -- 4.9 Conclusion and Outlook -- References Chapter 5 Mimicking Chemical Features of the Tumor Microenvironment -- 5.1 Introduction -- 5.2 Hallmarks of the Tumor Microenvironment -- 5.2.1 Components of the Tumor Microenvironment -- 5.3 Biomaterial Strategies to Mimic the Tumor Microenvironment -- 5.3.1 Natural Biomaterials -- 5.3.2 Synthetic Biomaterials -- 5.4 Recent Advances in Biomaterial Design for Cancer Research -- 5.5 Conclusion -- Disclosure Statement -- Abbreviations -- Acknowledgements -- References -- Chapter 6 Mimicking Multicellular Features of the Tumor Microenvironment -- 6.1 Introduction 6.1.1 Basic Concepts for Modelling the Tumour Microenvironment Tumors. http://id.loc.gov/authorities/subjects/sh85138553 Biomedical materials. http://id.loc.gov/authorities/subjects/sh85014239 Neoplasms https://id.nlm.nih.gov/mesh/D009369 Tumeurs. Biomatériaux. Biomedical materials fast Tumors fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85138553 http://id.loc.gov/authorities/subjects/sh85014239 https://id.nlm.nih.gov/mesh/D009369 |
| title | Biomaterial Based Approaches to Study the Tumour Microenvironment / |
| title_auth | Biomaterial Based Approaches to Study the Tumour Microenvironment / |
| title_exact_search | Biomaterial Based Approaches to Study the Tumour Microenvironment / |
| title_full | Biomaterial Based Approaches to Study the Tumour Microenvironment / editors: Jessica O. Winter, Shreyas Rao. |
| title_fullStr | Biomaterial Based Approaches to Study the Tumour Microenvironment / editors: Jessica O. Winter, Shreyas Rao. |
| title_full_unstemmed | Biomaterial Based Approaches to Study the Tumour Microenvironment / editors: Jessica O. Winter, Shreyas Rao. |
| title_short | Biomaterial Based Approaches to Study the Tumour Microenvironment / |
| title_sort | biomaterial based approaches to study the tumour microenvironment |
| topic | Tumors. http://id.loc.gov/authorities/subjects/sh85138553 Biomedical materials. http://id.loc.gov/authorities/subjects/sh85014239 Neoplasms https://id.nlm.nih.gov/mesh/D009369 Tumeurs. Biomatériaux. Biomedical materials fast Tumors fast |
| topic_facet | Tumors. Biomedical materials. Neoplasms Tumeurs. Biomatériaux. Biomedical materials Tumors |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3487865 |
| work_keys_str_mv | AT winterjessica biomaterialbasedapproachestostudythetumourmicroenvironment AT raoshreyas biomaterialbasedapproachestostudythetumourmicroenvironment |