Transcriptomics and their importance /:
"Transcriptomics refers to the study of the transcriptome, which is the complete set of RNA transcripts produced by the genome of a specific cell. This book provides an overview of the information that the transcriptome provides and how developments in transcriptomics has transformed our unders...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York :
Nova Science Publishers,
[2022]
|
| Schriftenreihe: | Cell Biology Research Progress Ser.
|
| Schlagworte: | |
| Online-Zugang: | DE-862 DE-863 |
| Zusammenfassung: | "Transcriptomics refers to the study of the transcriptome, which is the complete set of RNA transcripts produced by the genome of a specific cell. This book provides an overview of the information that the transcriptome provides and how developments in transcriptomics has transformed our understanding of cell biology. This book is comprised of three parts. Part I serves as an introduction to describe the development of transcriptomics as a technique and the way by which it has enhanced our knowledge and provided a better understanding of the basic biology of cellular function. Part II of the book is written to understand the milestones and contributions of transcriptomics in understanding the dynamics of cancer biology. Part III provides an insight on how transcriptomics is helping us to understand microbes and host-pathogen interaction including bioremediation"-- |
| Beschreibung: | 1 online resource. |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9798886972030 |
Internformat
MARC
| LEADER | 00000cam a22000008i 4500 | ||
|---|---|---|---|
| 001 | ZDB-4-EBA-on1343206393 | ||
| 003 | OCoLC | ||
| 005 | 20250103110447.0 | ||
| 006 | m o d | ||
| 007 | cr ||||||||||| | ||
| 008 | 220830s2022 nyu ob 001 0 eng | ||
| 010 | |a 2022040353 | ||
| 040 | |a DLC |b eng |e rda |c DLC |d YDX |d OCLCF |d OCLCO |d N$T |d EBLCP |d OCLCQ |d UKKRT | ||
| 019 | |a 1348483812 |a 1348491638 | ||
| 020 | |a 9798886972030 |q (electronic bk.) | ||
| 020 | |z 9798886970449 |q (hardcover) | ||
| 035 | |a (OCoLC)1343206393 |z (OCoLC)1348483812 |z (OCoLC)1348491638 | ||
| 042 | |a pcc | ||
| 050 | 0 | 0 | |a QH450.2 |
| 082 | 7 | |a 572.8/845 |2 23/eng/20220831 | |
| 049 | |a MAIN | ||
| 245 | 0 | 0 | |a Transcriptomics and their importance / |c Sarah Naiyer, PhD (editor), Research Scientist, Department of Microbiology and Immunology, University of Illinois at Chicago, USA, Khalid Hussain Bhat, PhD (editor), Assistant professor, Division of Basic Sciences and Humanities, FOA, Wadura, Sopore, SKUAST-Kashmir. |
| 263 | |a 2211 | ||
| 264 | 1 | |a New York : |b Nova Science Publishers, |c [2022] | |
| 300 | |a 1 online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Cell Biology Research Progress Ser. | |
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a "Transcriptomics refers to the study of the transcriptome, which is the complete set of RNA transcripts produced by the genome of a specific cell. This book provides an overview of the information that the transcriptome provides and how developments in transcriptomics has transformed our understanding of cell biology. This book is comprised of three parts. Part I serves as an introduction to describe the development of transcriptomics as a technique and the way by which it has enhanced our knowledge and provided a better understanding of the basic biology of cellular function. Part II of the book is written to understand the milestones and contributions of transcriptomics in understanding the dynamics of cancer biology. Part III provides an insight on how transcriptomics is helping us to understand microbes and host-pathogen interaction including bioremediation"-- |c Provided by publisher. | ||
| 588 | |a Description based on print version record and CIP data provided by publisher; resource not viewed. | ||
| 505 | 0 | |a Intro -- Contents -- Preface -- Acknowledgments -- List of Acronyms -- Part I. Introduction to Transcriptomics -- Chapter 1 -- The Nuts and Bolts in Transcriptomics -- Abstract -- 1. Introduction -- 2. History towards the Development of Transcriptomics -- 3. RNA Sequencing (RNA-Seq) -- 3.1. Advances in RNA-Seq -- 4. Computational Analysis of RNA Sequencing Data -- 4.1. Quality Control of Raw Data -- 4.2. Read Alignment and Transcript Assembly -- 4.3. Expression Quantification -- 4.4. Differential Expression Analysis -- Conclusion and Further Advancements in Transcriptomic Analysis | |
| 505 | 8 | |a 4. Transcriptomics and Its Role in Understanding Cellular Function -- 4.1. Understanding Host Pathogen Interactions -- 4.2. Disease Profiling and Pathogenesis -- Conclusion -- References -- Part II. Understanding Cancer with Transcriptomics -- Chapter 3 -- Transcriptomics in Basic Cancer Biology -- Abstract -- 1. History of Gene Expression Techniques-Brief Introduction -- 2. RNA-Based Therapeutics -- 2.1. Tumor Heterogeneity and RNA-seq -- 2.2. Transcriptomics in Clinical Classifications of Cancer -- 2.3. Identification of Cancer Biomarkers for Early Detection | |
| 505 | 8 | |a 3. Applications of RNA-Sequencing in Cancer Research -- 3.1. Cancer Variance and Adaptation -- 3.2. Cancer Drug Tolerance -- 3.3. Differential Gene Expression and Cancer Biomarkers -- 3.4. Cancer Immunotherapy -- 4. Application of Transcriptomics in Cancer Diagnostic -- 4.1. Breast Cancer -- 4.2. Colorectal Cancer -- 4.3. Lung Cancer -- 4.4. Prostate Cancer -- 4.5. Skin Cancer -- 4.6. Thyroid Cancer -- 5. Challenges and Limitations -- 5.1. Construction of Library -- 5.2. Cost vs Coverage -- 5.3. Bioinformatic Challenges -- Conclusion and Future Prospects -- References -- Chapter 4 | |
| 505 | 8 | |a Single-Cell Transcriptomics in Cancer Stem Cells (CSCs): Implications in Carcinogenesis and Drug Resistance -- Abstract -- 1. Introduction -- 2. Role of CSCs in Tumor Heterogeneity: Impact on Cancer Progression and Drug Resistance -- 3. Application of Single-Cell Transcriptomics in CSCs -- 4. Role of Single-Cell Transcriptomics in Personalised Therapy -- 5. Limitation of SCT in CSCs Driven Cancer -- Conclusion and Future Prospects -- References -- Chapter 5 -- Transcriptome: A Tool for Precision Oncology -- Abstract -- 1. Introduction | |
| 650 | 0 | |a Genetic transcription. |0 http://id.loc.gov/authorities/subjects/sh85053872 | |
| 650 | 0 | |a RNA editing. |0 http://id.loc.gov/authorities/subjects/sh93000171 | |
| 650 | 6 | |a Transcription génétique. | |
| 650 | 6 | |a ARN |x Édition. | |
| 650 | 7 | |a Genetic transcription |2 fast | |
| 650 | 7 | |a RNA editing |2 fast | |
| 655 | 0 | |a Electronic books. | |
| 700 | 1 | |a Naiyer, Sarah, |e editor. | |
| 700 | 1 | |a Bhat, Khalid Hussain, |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Transcriptomics and their importance |d New York : Nova Science Publishers, [2022] |z 9798886970449 |w (DLC) 2022040352 |
| 830 | 0 | |a Cell Biology Research Progress Ser. | |
| 966 | 4 | 0 | |l DE-862 |p ZDB-4-EBA |q FWS_PDA_EBA |u https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3344239 |3 Volltext |
| 966 | 4 | 0 | |l DE-863 |p ZDB-4-EBA |q FWS_PDA_EBA |u https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3344239 |3 Volltext |
| 938 | |a Kortext |b KTXT |n 2072586 | ||
| 938 | |a YBP Library Services |b YANK |n 18161649 | ||
| 938 | |a EBSCOhost |b EBSC |n 3344239 | ||
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL30174205 | ||
| 938 | |a Askews and Holts Library Services |b ASKH |n AH40882319 | ||
| 994 | |a 92 |b GEBAY | ||
| 912 | |a ZDB-4-EBA | ||
| 049 | |a DE-862 | ||
| 049 | |a DE-863 | ||
Datensatz im Suchindex
| DE-BY-FWS_katkey | ZDB-4-EBA-on1343206393 |
|---|---|
| _version_ | 1829095374604730368 |
| adam_text | |
| any_adam_object | |
| author2 | Naiyer, Sarah Bhat, Khalid Hussain |
| author2_role | edt edt |
| author2_variant | s n sn k h b kh khb |
| author_facet | Naiyer, Sarah Bhat, Khalid Hussain |
| building | Verbundindex |
| bvnumber | localFWS |
| callnumber-first | Q - Science |
| callnumber-label | QH450 |
| callnumber-raw | QH450.2 |
| callnumber-search | QH450.2 |
| callnumber-sort | QH 3450.2 |
| callnumber-subject | QH - Natural History and Biology |
| collection | ZDB-4-EBA |
| contents | Intro -- Contents -- Preface -- Acknowledgments -- List of Acronyms -- Part I. Introduction to Transcriptomics -- Chapter 1 -- The Nuts and Bolts in Transcriptomics -- Abstract -- 1. Introduction -- 2. History towards the Development of Transcriptomics -- 3. RNA Sequencing (RNA-Seq) -- 3.1. Advances in RNA-Seq -- 4. Computational Analysis of RNA Sequencing Data -- 4.1. Quality Control of Raw Data -- 4.2. Read Alignment and Transcript Assembly -- 4.3. Expression Quantification -- 4.4. Differential Expression Analysis -- Conclusion and Further Advancements in Transcriptomic Analysis 4. Transcriptomics and Its Role in Understanding Cellular Function -- 4.1. Understanding Host Pathogen Interactions -- 4.2. Disease Profiling and Pathogenesis -- Conclusion -- References -- Part II. Understanding Cancer with Transcriptomics -- Chapter 3 -- Transcriptomics in Basic Cancer Biology -- Abstract -- 1. History of Gene Expression Techniques-Brief Introduction -- 2. RNA-Based Therapeutics -- 2.1. Tumor Heterogeneity and RNA-seq -- 2.2. Transcriptomics in Clinical Classifications of Cancer -- 2.3. Identification of Cancer Biomarkers for Early Detection 3. Applications of RNA-Sequencing in Cancer Research -- 3.1. Cancer Variance and Adaptation -- 3.2. Cancer Drug Tolerance -- 3.3. Differential Gene Expression and Cancer Biomarkers -- 3.4. Cancer Immunotherapy -- 4. Application of Transcriptomics in Cancer Diagnostic -- 4.1. Breast Cancer -- 4.2. Colorectal Cancer -- 4.3. Lung Cancer -- 4.4. Prostate Cancer -- 4.5. Skin Cancer -- 4.6. Thyroid Cancer -- 5. Challenges and Limitations -- 5.1. Construction of Library -- 5.2. Cost vs Coverage -- 5.3. Bioinformatic Challenges -- Conclusion and Future Prospects -- References -- Chapter 4 Single-Cell Transcriptomics in Cancer Stem Cells (CSCs): Implications in Carcinogenesis and Drug Resistance -- Abstract -- 1. Introduction -- 2. Role of CSCs in Tumor Heterogeneity: Impact on Cancer Progression and Drug Resistance -- 3. Application of Single-Cell Transcriptomics in CSCs -- 4. Role of Single-Cell Transcriptomics in Personalised Therapy -- 5. Limitation of SCT in CSCs Driven Cancer -- Conclusion and Future Prospects -- References -- Chapter 5 -- Transcriptome: A Tool for Precision Oncology -- Abstract -- 1. Introduction |
| ctrlnum | (OCoLC)1343206393 |
| dewey-full | 572.8/845 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572.8/845 |
| dewey-search | 572.8/845 |
| dewey-sort | 3572.8 3845 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>05716cam a22006138i 4500</leader><controlfield tag="001">ZDB-4-EBA-on1343206393</controlfield><controlfield tag="003">OCoLC</controlfield><controlfield tag="005">20250103110447.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr |||||||||||</controlfield><controlfield tag="008">220830s2022 nyu ob 001 0 eng </controlfield><datafield tag="010" ind1=" " ind2=" "><subfield code="a"> 2022040353</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DLC</subfield><subfield code="b">eng</subfield><subfield code="e">rda</subfield><subfield code="c">DLC</subfield><subfield code="d">YDX</subfield><subfield code="d">OCLCF</subfield><subfield code="d">OCLCO</subfield><subfield code="d">N$T</subfield><subfield code="d">EBLCP</subfield><subfield code="d">OCLCQ</subfield><subfield code="d">UKKRT</subfield></datafield><datafield tag="019" ind1=" " ind2=" "><subfield code="a">1348483812</subfield><subfield code="a">1348491638</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9798886972030</subfield><subfield code="q">(electronic bk.)</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="z">9798886970449</subfield><subfield code="q">(hardcover)</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1343206393</subfield><subfield code="z">(OCoLC)1348483812</subfield><subfield code="z">(OCoLC)1348491638</subfield></datafield><datafield tag="042" ind1=" " ind2=" "><subfield code="a">pcc</subfield></datafield><datafield tag="050" ind1="0" ind2="0"><subfield code="a">QH450.2</subfield></datafield><datafield tag="082" ind1="7" ind2=" "><subfield code="a">572.8/845</subfield><subfield code="2">23/eng/20220831</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">MAIN</subfield></datafield><datafield tag="245" ind1="0" ind2="0"><subfield code="a">Transcriptomics and their importance /</subfield><subfield code="c">Sarah Naiyer, PhD (editor), Research Scientist, Department of Microbiology and Immunology, University of Illinois at Chicago, USA, Khalid Hussain Bhat, PhD (editor), Assistant professor, Division of Basic Sciences and Humanities, FOA, Wadura, Sopore, SKUAST-Kashmir.</subfield></datafield><datafield tag="263" ind1=" " ind2=" "><subfield code="a">2211</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">New York :</subfield><subfield code="b">Nova Science Publishers,</subfield><subfield code="c">[2022]</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="1" ind2=" "><subfield code="a">Cell Biology Research Progress Ser.</subfield></datafield><datafield tag="504" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references and index.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">"Transcriptomics refers to the study of the transcriptome, which is the complete set of RNA transcripts produced by the genome of a specific cell. This book provides an overview of the information that the transcriptome provides and how developments in transcriptomics has transformed our understanding of cell biology. This book is comprised of three parts. Part I serves as an introduction to describe the development of transcriptomics as a technique and the way by which it has enhanced our knowledge and provided a better understanding of the basic biology of cellular function. Part II of the book is written to understand the milestones and contributions of transcriptomics in understanding the dynamics of cancer biology. Part III provides an insight on how transcriptomics is helping us to understand microbes and host-pathogen interaction including bioremediation"--</subfield><subfield code="c">Provided by publisher.</subfield></datafield><datafield tag="588" ind1=" " ind2=" "><subfield code="a">Description based on print version record and CIP data provided by publisher; resource not viewed.</subfield></datafield><datafield tag="505" ind1="0" ind2=" "><subfield code="a">Intro -- Contents -- Preface -- Acknowledgments -- List of Acronyms -- Part I. Introduction to Transcriptomics -- Chapter 1 -- The Nuts and Bolts in Transcriptomics -- Abstract -- 1. Introduction -- 2. History towards the Development of Transcriptomics -- 3. RNA Sequencing (RNA-Seq) -- 3.1. Advances in RNA-Seq -- 4. Computational Analysis of RNA Sequencing Data -- 4.1. Quality Control of Raw Data -- 4.2. Read Alignment and Transcript Assembly -- 4.3. Expression Quantification -- 4.4. Differential Expression Analysis -- Conclusion and Further Advancements in Transcriptomic Analysis</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">4. Transcriptomics and Its Role in Understanding Cellular Function -- 4.1. Understanding Host Pathogen Interactions -- 4.2. Disease Profiling and Pathogenesis -- Conclusion -- References -- Part II. Understanding Cancer with Transcriptomics -- Chapter 3 -- Transcriptomics in Basic Cancer Biology -- Abstract -- 1. History of Gene Expression Techniques-Brief Introduction -- 2. RNA-Based Therapeutics -- 2.1. Tumor Heterogeneity and RNA-seq -- 2.2. Transcriptomics in Clinical Classifications of Cancer -- 2.3. Identification of Cancer Biomarkers for Early Detection</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">3. Applications of RNA-Sequencing in Cancer Research -- 3.1. Cancer Variance and Adaptation -- 3.2. Cancer Drug Tolerance -- 3.3. Differential Gene Expression and Cancer Biomarkers -- 3.4. Cancer Immunotherapy -- 4. Application of Transcriptomics in Cancer Diagnostic -- 4.1. Breast Cancer -- 4.2. Colorectal Cancer -- 4.3. Lung Cancer -- 4.4. Prostate Cancer -- 4.5. Skin Cancer -- 4.6. Thyroid Cancer -- 5. Challenges and Limitations -- 5.1. Construction of Library -- 5.2. Cost vs Coverage -- 5.3. Bioinformatic Challenges -- Conclusion and Future Prospects -- References -- Chapter 4</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">Single-Cell Transcriptomics in Cancer Stem Cells (CSCs): Implications in Carcinogenesis and Drug Resistance -- Abstract -- 1. Introduction -- 2. Role of CSCs in Tumor Heterogeneity: Impact on Cancer Progression and Drug Resistance -- 3. Application of Single-Cell Transcriptomics in CSCs -- 4. Role of Single-Cell Transcriptomics in Personalised Therapy -- 5. Limitation of SCT in CSCs Driven Cancer -- Conclusion and Future Prospects -- References -- Chapter 5 -- Transcriptome: A Tool for Precision Oncology -- Abstract -- 1. Introduction</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">Genetic transcription.</subfield><subfield code="0">http://id.loc.gov/authorities/subjects/sh85053872</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">RNA editing.</subfield><subfield code="0">http://id.loc.gov/authorities/subjects/sh93000171</subfield></datafield><datafield tag="650" ind1=" " ind2="6"><subfield code="a">Transcription génétique.</subfield></datafield><datafield tag="650" ind1=" " ind2="6"><subfield code="a">ARN</subfield><subfield code="x">Édition.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Genetic transcription</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">RNA editing</subfield><subfield code="2">fast</subfield></datafield><datafield tag="655" ind1=" " ind2="0"><subfield code="a">Electronic books.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Naiyer, Sarah,</subfield><subfield code="e">editor.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bhat, Khalid Hussain,</subfield><subfield code="e">editor.</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Print version:</subfield><subfield code="t">Transcriptomics and their importance</subfield><subfield code="d">New York : Nova Science Publishers, [2022]</subfield><subfield code="z">9798886970449</subfield><subfield code="w">(DLC) 2022040352</subfield></datafield><datafield tag="830" ind1=" " ind2="0"><subfield code="a">Cell Biology Research Progress Ser.</subfield></datafield><datafield tag="966" ind1="4" ind2="0"><subfield code="l">DE-862</subfield><subfield code="p">ZDB-4-EBA</subfield><subfield code="q">FWS_PDA_EBA</subfield><subfield code="u">https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3344239</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="4" ind2="0"><subfield code="l">DE-863</subfield><subfield code="p">ZDB-4-EBA</subfield><subfield code="q">FWS_PDA_EBA</subfield><subfield code="u">https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3344239</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">Kortext</subfield><subfield code="b">KTXT</subfield><subfield code="n">2072586</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">YBP Library Services</subfield><subfield code="b">YANK</subfield><subfield code="n">18161649</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">EBSCOhost</subfield><subfield code="b">EBSC</subfield><subfield code="n">3344239</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">ProQuest Ebook Central</subfield><subfield code="b">EBLB</subfield><subfield code="n">EBL30174205</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">Askews and Holts Library Services</subfield><subfield code="b">ASKH</subfield><subfield code="n">AH40882319</subfield></datafield><datafield tag="994" ind1=" " ind2=" "><subfield code="a">92</subfield><subfield code="b">GEBAY</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-4-EBA</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-862</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-863</subfield></datafield></record></collection> |
| genre | Electronic books. |
| genre_facet | Electronic books. |
| id | ZDB-4-EBA-on1343206393 |
| illustrated | Not Illustrated |
| indexdate | 2025-04-11T08:48:00Z |
| institution | BVB |
| isbn | 9798886972030 |
| language | English |
| lccn | 2022040353 |
| oclc_num | 1343206393 |
| open_access_boolean | |
| owner | MAIN DE-862 DE-BY-FWS DE-863 DE-BY-FWS |
| owner_facet | MAIN DE-862 DE-BY-FWS DE-863 DE-BY-FWS |
| physical | 1 online resource. |
| psigel | ZDB-4-EBA FWS_PDA_EBA ZDB-4-EBA |
| publishDate | 2022 |
| publishDateSearch | 2022 |
| publishDateSort | 2022 |
| publisher | Nova Science Publishers, |
| record_format | marc |
| series | Cell Biology Research Progress Ser. |
| series2 | Cell Biology Research Progress Ser. |
| spelling | Transcriptomics and their importance / Sarah Naiyer, PhD (editor), Research Scientist, Department of Microbiology and Immunology, University of Illinois at Chicago, USA, Khalid Hussain Bhat, PhD (editor), Assistant professor, Division of Basic Sciences and Humanities, FOA, Wadura, Sopore, SKUAST-Kashmir. 2211 New York : Nova Science Publishers, [2022] 1 online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier Cell Biology Research Progress Ser. Includes bibliographical references and index. "Transcriptomics refers to the study of the transcriptome, which is the complete set of RNA transcripts produced by the genome of a specific cell. This book provides an overview of the information that the transcriptome provides and how developments in transcriptomics has transformed our understanding of cell biology. This book is comprised of three parts. Part I serves as an introduction to describe the development of transcriptomics as a technique and the way by which it has enhanced our knowledge and provided a better understanding of the basic biology of cellular function. Part II of the book is written to understand the milestones and contributions of transcriptomics in understanding the dynamics of cancer biology. Part III provides an insight on how transcriptomics is helping us to understand microbes and host-pathogen interaction including bioremediation"-- Provided by publisher. Description based on print version record and CIP data provided by publisher; resource not viewed. Intro -- Contents -- Preface -- Acknowledgments -- List of Acronyms -- Part I. Introduction to Transcriptomics -- Chapter 1 -- The Nuts and Bolts in Transcriptomics -- Abstract -- 1. Introduction -- 2. History towards the Development of Transcriptomics -- 3. RNA Sequencing (RNA-Seq) -- 3.1. Advances in RNA-Seq -- 4. Computational Analysis of RNA Sequencing Data -- 4.1. Quality Control of Raw Data -- 4.2. Read Alignment and Transcript Assembly -- 4.3. Expression Quantification -- 4.4. Differential Expression Analysis -- Conclusion and Further Advancements in Transcriptomic Analysis 4. Transcriptomics and Its Role in Understanding Cellular Function -- 4.1. Understanding Host Pathogen Interactions -- 4.2. Disease Profiling and Pathogenesis -- Conclusion -- References -- Part II. Understanding Cancer with Transcriptomics -- Chapter 3 -- Transcriptomics in Basic Cancer Biology -- Abstract -- 1. History of Gene Expression Techniques-Brief Introduction -- 2. RNA-Based Therapeutics -- 2.1. Tumor Heterogeneity and RNA-seq -- 2.2. Transcriptomics in Clinical Classifications of Cancer -- 2.3. Identification of Cancer Biomarkers for Early Detection 3. Applications of RNA-Sequencing in Cancer Research -- 3.1. Cancer Variance and Adaptation -- 3.2. Cancer Drug Tolerance -- 3.3. Differential Gene Expression and Cancer Biomarkers -- 3.4. Cancer Immunotherapy -- 4. Application of Transcriptomics in Cancer Diagnostic -- 4.1. Breast Cancer -- 4.2. Colorectal Cancer -- 4.3. Lung Cancer -- 4.4. Prostate Cancer -- 4.5. Skin Cancer -- 4.6. Thyroid Cancer -- 5. Challenges and Limitations -- 5.1. Construction of Library -- 5.2. Cost vs Coverage -- 5.3. Bioinformatic Challenges -- Conclusion and Future Prospects -- References -- Chapter 4 Single-Cell Transcriptomics in Cancer Stem Cells (CSCs): Implications in Carcinogenesis and Drug Resistance -- Abstract -- 1. Introduction -- 2. Role of CSCs in Tumor Heterogeneity: Impact on Cancer Progression and Drug Resistance -- 3. Application of Single-Cell Transcriptomics in CSCs -- 4. Role of Single-Cell Transcriptomics in Personalised Therapy -- 5. Limitation of SCT in CSCs Driven Cancer -- Conclusion and Future Prospects -- References -- Chapter 5 -- Transcriptome: A Tool for Precision Oncology -- Abstract -- 1. Introduction Genetic transcription. http://id.loc.gov/authorities/subjects/sh85053872 RNA editing. http://id.loc.gov/authorities/subjects/sh93000171 Transcription génétique. ARN Édition. Genetic transcription fast RNA editing fast Electronic books. Naiyer, Sarah, editor. Bhat, Khalid Hussain, editor. Print version: Transcriptomics and their importance New York : Nova Science Publishers, [2022] 9798886970449 (DLC) 2022040352 |
| spellingShingle | Transcriptomics and their importance / Cell Biology Research Progress Ser. Intro -- Contents -- Preface -- Acknowledgments -- List of Acronyms -- Part I. Introduction to Transcriptomics -- Chapter 1 -- The Nuts and Bolts in Transcriptomics -- Abstract -- 1. Introduction -- 2. History towards the Development of Transcriptomics -- 3. RNA Sequencing (RNA-Seq) -- 3.1. Advances in RNA-Seq -- 4. Computational Analysis of RNA Sequencing Data -- 4.1. Quality Control of Raw Data -- 4.2. Read Alignment and Transcript Assembly -- 4.3. Expression Quantification -- 4.4. Differential Expression Analysis -- Conclusion and Further Advancements in Transcriptomic Analysis 4. Transcriptomics and Its Role in Understanding Cellular Function -- 4.1. Understanding Host Pathogen Interactions -- 4.2. Disease Profiling and Pathogenesis -- Conclusion -- References -- Part II. Understanding Cancer with Transcriptomics -- Chapter 3 -- Transcriptomics in Basic Cancer Biology -- Abstract -- 1. History of Gene Expression Techniques-Brief Introduction -- 2. RNA-Based Therapeutics -- 2.1. Tumor Heterogeneity and RNA-seq -- 2.2. Transcriptomics in Clinical Classifications of Cancer -- 2.3. Identification of Cancer Biomarkers for Early Detection 3. Applications of RNA-Sequencing in Cancer Research -- 3.1. Cancer Variance and Adaptation -- 3.2. Cancer Drug Tolerance -- 3.3. Differential Gene Expression and Cancer Biomarkers -- 3.4. Cancer Immunotherapy -- 4. Application of Transcriptomics in Cancer Diagnostic -- 4.1. Breast Cancer -- 4.2. Colorectal Cancer -- 4.3. Lung Cancer -- 4.4. Prostate Cancer -- 4.5. Skin Cancer -- 4.6. Thyroid Cancer -- 5. Challenges and Limitations -- 5.1. Construction of Library -- 5.2. Cost vs Coverage -- 5.3. Bioinformatic Challenges -- Conclusion and Future Prospects -- References -- Chapter 4 Single-Cell Transcriptomics in Cancer Stem Cells (CSCs): Implications in Carcinogenesis and Drug Resistance -- Abstract -- 1. Introduction -- 2. Role of CSCs in Tumor Heterogeneity: Impact on Cancer Progression and Drug Resistance -- 3. Application of Single-Cell Transcriptomics in CSCs -- 4. Role of Single-Cell Transcriptomics in Personalised Therapy -- 5. Limitation of SCT in CSCs Driven Cancer -- Conclusion and Future Prospects -- References -- Chapter 5 -- Transcriptome: A Tool for Precision Oncology -- Abstract -- 1. Introduction Genetic transcription. http://id.loc.gov/authorities/subjects/sh85053872 RNA editing. http://id.loc.gov/authorities/subjects/sh93000171 Transcription génétique. ARN Édition. Genetic transcription fast RNA editing fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85053872 http://id.loc.gov/authorities/subjects/sh93000171 |
| title | Transcriptomics and their importance / |
| title_auth | Transcriptomics and their importance / |
| title_exact_search | Transcriptomics and their importance / |
| title_full | Transcriptomics and their importance / Sarah Naiyer, PhD (editor), Research Scientist, Department of Microbiology and Immunology, University of Illinois at Chicago, USA, Khalid Hussain Bhat, PhD (editor), Assistant professor, Division of Basic Sciences and Humanities, FOA, Wadura, Sopore, SKUAST-Kashmir. |
| title_fullStr | Transcriptomics and their importance / Sarah Naiyer, PhD (editor), Research Scientist, Department of Microbiology and Immunology, University of Illinois at Chicago, USA, Khalid Hussain Bhat, PhD (editor), Assistant professor, Division of Basic Sciences and Humanities, FOA, Wadura, Sopore, SKUAST-Kashmir. |
| title_full_unstemmed | Transcriptomics and their importance / Sarah Naiyer, PhD (editor), Research Scientist, Department of Microbiology and Immunology, University of Illinois at Chicago, USA, Khalid Hussain Bhat, PhD (editor), Assistant professor, Division of Basic Sciences and Humanities, FOA, Wadura, Sopore, SKUAST-Kashmir. |
| title_short | Transcriptomics and their importance / |
| title_sort | transcriptomics and their importance |
| topic | Genetic transcription. http://id.loc.gov/authorities/subjects/sh85053872 RNA editing. http://id.loc.gov/authorities/subjects/sh93000171 Transcription génétique. ARN Édition. Genetic transcription fast RNA editing fast |
| topic_facet | Genetic transcription. RNA editing. Transcription génétique. ARN Édition. Genetic transcription RNA editing Electronic books. |
| work_keys_str_mv | AT naiyersarah transcriptomicsandtheirimportance AT bhatkhalidhussain transcriptomicsandtheirimportance |