DNA Photodamage: From Light Absorption to Cellular Responses and Skin Cancer.
Written in an accessible and comprehensive manner, DNA Photodamage will appeal to all scientists working in the area whether specialists in the discipline or not and provides a complete coverage of the field, from ultrafast spectroscopy to biomedical research.
Saved in:
| Other Authors: | , |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Cambridge :
Royal Society of Chemistry,
[2022]
|
| Series: | ISSN.
|
| Subjects: | |
| Online Access: | DE-862 DE-863 |
| Summary: | Written in an accessible and comprehensive manner, DNA Photodamage will appeal to all scientists working in the area whether specialists in the discipline or not and provides a complete coverage of the field, from ultrafast spectroscopy to biomedical research. |
| Item Description: | Description based upon print version of record. Chapter 6 Influence of DNA Structure on Lesion Formation and Repair: Role of Modelling and Simulations 105. |
| Physical Description: | 1 online resource (387 p.). |
| ISBN: | 1839165596 9781839165597 |
Staff View
MARC
| LEADER | 00000cam a2200000Mu 4500 | ||
|---|---|---|---|
| 001 | ZDB-4-EBA-on1288215255 | ||
| 003 | OCoLC | ||
| 005 | 20250103110447.0 | ||
| 006 | m o d | ||
| 007 | cr cnu---unuuu | ||
| 008 | 211211s2022 xx o ||| 0 eng d | ||
| 040 | |a EBLCP |b eng |c EBLCP |d N$T |d OCLCO |d OCLCF |d OCLCO |d OCLCQ |d OCLCO | ||
| 020 | |a 1839165596 | ||
| 020 | |a 9781839165597 |q (electronic bk.) | ||
| 035 | |a (OCoLC)1288215255 | ||
| 050 | 4 | |a QH465 | |
| 082 | 7 | |a 572.86 |2 23 | |
| 049 | |a MAIN | ||
| 245 | 0 | 0 | |a DNA Photodamage |h [electronic resource] : |b From Light Absorption to Cellular Responses and Skin Cancer. |
| 260 | |a Cambridge : |b Royal Society of Chemistry, |c [2022] | ||
| 300 | |a 1 online resource (387 p.). | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a ISSN | |
| 500 | |a Description based upon print version of record. | ||
| 505 | 0 | |a Intro -- Half Title -- Series Title -- Title -- Copyright -- Contents -- Preface -- Chapter 1 Photoinduced Processes in DNA: Basic Theoretical and Experimental Features 1 -- 1.1 Introduction -- 1.2 A Theoretical Basis -- 1.3 Notion of Spectrum in Photobiology -- 1.3.1 Emission Spectrum of the Light Source -- 1.3.2 Absorption Spectrum -- 1.3.3 Action Spectrum -- 1.4 A Basic Introduction to Pump-probe Spectroscopies -- 1.5 Analytical Tools for the Detection of DNA Damage -- 1.5.1 Antibody-based Assays -- 1.5.2 Electrophoresis-based Assays -- 1.5.3 Chromatography-based Assays | |
| 505 | 8 | |a 1.6 Basic Biological Phenomena Associated with DNA Damage -- 1.6.1 From DNA Damage to Abnormal Proteins -- 1.6.2 Principle of DNA Repair -- Acknowledgements -- References -- Chapter 2 Photoinduced Dimerization in DNA: Singlet Excited State Reaction Paths 17 -- 2.1 Introduction -- 2.2 Pyrimidine Dimers -- 2.2.1 Mechanism of Thymine-Thymine Photodimerization -- 2.2.2 Cytosine-Thymine -- 2.3 Purine-Purine and Purine-Pyrimidine Dimers -- 2.4 Concluding Remarks -- Acknowledgements -- References -- Chapter 3 DNA Photoionization: From High to Low Energies 37 -- 3.1 Introduction | |
| 505 | 8 | |a 3.2 Energies and Quantum Yields -- 3.2.1 Direct High-energy Photoionization -- 3.2.2 Indirect Low-energy Photoionization -- 3.3 Nanosecond Flash Photolysis: Advantages and Limitations -- 3.4 Evolution of Ejected Electrons -- 3.5 Evolution of Purine Radicals -- 3.5.1 Deprotonation and Tautomerization -- 3.5.2 Radical Populations -- 3.5.3 Reaction Dynamics -- 3.6 Final Lesions -- Acknowledgements -- References -- Chapter 4 Triplet Channel Photochemistry in DNA 55 -- 4.1 Introduction -- 4.2 Formation of Nucleobase Triplet Excited State | |
| 505 | 8 | |a 4.2.1 Intrinsic Population of Nucleobase Triplet Excited State -- 4.2.2 Photosensitized Population of the Lowest Nucleobases Triplet Excited State -- 4.2.3 Triplet-Triplet Energy Transfer Within the Helix -- 4.3 Photoreactivity -- 4.3.1 Cyclobutane Pyrimidine Dimers Formation -- 4.3.2 Spore Photoproduct Formation -- 4.3.3 Formation of (6-4) Photoproduct -- 4.3.4 Reactivity from Upper Triplet Excited States -- 4.4 Conclusion -- References -- Chapter 5 Tracking Excited Electronic States in DNA From Formation to Deactivation 77 -- 5.1 Introduction | |
| 505 | 8 | |a 5.2 Excited States of DNA: Their Nature and Steady-state Spectra -- 5.2.1 Electronic Absorption Spectra and Lineshapes -- 5.2.2 Exciton Theory and Coupled Chromophores -- 5.3 Excited States of DNA: Dynamic Properties -- 5.3.1 Dynamics of Base Monomer Excited States -- 5.3.2 Dynamics of DNA Strand Excited States -- 5.3.3 Long-lived Intrastrand CT States -- 5.3.4 Formation and Decay of CT States -- 5.3.5 Excited-state Proton Transfer in Double Strands -- 5.3.6 Conformational Dynamics and Excited State Dynamics -- 5.4 Outlook -- References | |
| 500 | |a Chapter 6 Influence of DNA Structure on Lesion Formation and Repair: Role of Modelling and Simulations 105. | ||
| 520 | |a Written in an accessible and comprehensive manner, DNA Photodamage will appeal to all scientists working in the area whether specialists in the discipline or not and provides a complete coverage of the field, from ultrafast spectroscopy to biomedical research. | ||
| 650 | 0 | |a DNA damage. |0 http://id.loc.gov/authorities/subjects/sh88006186 | |
| 650 | 0 | |a DNA. |0 http://id.loc.gov/authorities/subjects/sh85037008 | |
| 650 | 2 | |a DNA Damage |0 https://id.nlm.nih.gov/mesh/D004249 | |
| 650 | 2 | |a DNA |0 https://id.nlm.nih.gov/mesh/D004247 | |
| 650 | 6 | |a ADN |x Lésions. | |
| 650 | 6 | |a ADN. | |
| 650 | 7 | |a DNA |2 fast | |
| 650 | 7 | |a DNA damage |2 fast | |
| 700 | 1 | |a Improta, Roberto. | |
| 700 | 1 | |a Douki, Thierry. | |
| 776 | 0 | 8 | |i Print version: |a Improta, Roberto |t DNA Photodamage |d Cambridge : Royal Society of Chemistry,c2021 |z 9781839161964 |
| 830 | 0 | |a ISSN. | |
| 966 | 4 | 0 | |l DE-862 |p ZDB-4-EBA |q FWS_PDA_EBA |u https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3117509 |3 Volltext |
| 966 | 4 | 0 | |l DE-863 |p ZDB-4-EBA |q FWS_PDA_EBA |u https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3117509 |3 Volltext |
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL6823151 | ||
| 938 | |a EBSCOhost |b EBSC |n 3117509 | ||
| 994 | |a 92 |b GEBAY | ||
| 912 | |a ZDB-4-EBA | ||
| 049 | |a DE-862 | ||
| 049 | |a DE-863 | ||
Record in the Search Index
| DE-BY-FWS_katkey | ZDB-4-EBA-on1288215255 |
|---|---|
| _version_ | 1829095363943858176 |
| adam_text | |
| any_adam_object | |
| author2 | Improta, Roberto Douki, Thierry |
| author2_role | |
| author2_variant | r i ri t d td |
| author_facet | Improta, Roberto Douki, Thierry |
| author_sort | Improta, Roberto |
| building | Verbundindex |
| bvnumber | localFWS |
| callnumber-first | Q - Science |
| callnumber-label | QH465 |
| callnumber-raw | QH465 |
| callnumber-search | QH465 |
| callnumber-sort | QH 3465 |
| callnumber-subject | QH - Natural History and Biology |
| collection | ZDB-4-EBA |
| contents | Intro -- Half Title -- Series Title -- Title -- Copyright -- Contents -- Preface -- Chapter 1 Photoinduced Processes in DNA: Basic Theoretical and Experimental Features 1 -- 1.1 Introduction -- 1.2 A Theoretical Basis -- 1.3 Notion of Spectrum in Photobiology -- 1.3.1 Emission Spectrum of the Light Source -- 1.3.2 Absorption Spectrum -- 1.3.3 Action Spectrum -- 1.4 A Basic Introduction to Pump-probe Spectroscopies -- 1.5 Analytical Tools for the Detection of DNA Damage -- 1.5.1 Antibody-based Assays -- 1.5.2 Electrophoresis-based Assays -- 1.5.3 Chromatography-based Assays 1.6 Basic Biological Phenomena Associated with DNA Damage -- 1.6.1 From DNA Damage to Abnormal Proteins -- 1.6.2 Principle of DNA Repair -- Acknowledgements -- References -- Chapter 2 Photoinduced Dimerization in DNA: Singlet Excited State Reaction Paths 17 -- 2.1 Introduction -- 2.2 Pyrimidine Dimers -- 2.2.1 Mechanism of Thymine-Thymine Photodimerization -- 2.2.2 Cytosine-Thymine -- 2.3 Purine-Purine and Purine-Pyrimidine Dimers -- 2.4 Concluding Remarks -- Acknowledgements -- References -- Chapter 3 DNA Photoionization: From High to Low Energies 37 -- 3.1 Introduction 3.2 Energies and Quantum Yields -- 3.2.1 Direct High-energy Photoionization -- 3.2.2 Indirect Low-energy Photoionization -- 3.3 Nanosecond Flash Photolysis: Advantages and Limitations -- 3.4 Evolution of Ejected Electrons -- 3.5 Evolution of Purine Radicals -- 3.5.1 Deprotonation and Tautomerization -- 3.5.2 Radical Populations -- 3.5.3 Reaction Dynamics -- 3.6 Final Lesions -- Acknowledgements -- References -- Chapter 4 Triplet Channel Photochemistry in DNA 55 -- 4.1 Introduction -- 4.2 Formation of Nucleobase Triplet Excited State 4.2.1 Intrinsic Population of Nucleobase Triplet Excited State -- 4.2.2 Photosensitized Population of the Lowest Nucleobases Triplet Excited State -- 4.2.3 Triplet-Triplet Energy Transfer Within the Helix -- 4.3 Photoreactivity -- 4.3.1 Cyclobutane Pyrimidine Dimers Formation -- 4.3.2 Spore Photoproduct Formation -- 4.3.3 Formation of (6-4) Photoproduct -- 4.3.4 Reactivity from Upper Triplet Excited States -- 4.4 Conclusion -- References -- Chapter 5 Tracking Excited Electronic States in DNA From Formation to Deactivation 77 -- 5.1 Introduction 5.2 Excited States of DNA: Their Nature and Steady-state Spectra -- 5.2.1 Electronic Absorption Spectra and Lineshapes -- 5.2.2 Exciton Theory and Coupled Chromophores -- 5.3 Excited States of DNA: Dynamic Properties -- 5.3.1 Dynamics of Base Monomer Excited States -- 5.3.2 Dynamics of DNA Strand Excited States -- 5.3.3 Long-lived Intrastrand CT States -- 5.3.4 Formation and Decay of CT States -- 5.3.5 Excited-state Proton Transfer in Double Strands -- 5.3.6 Conformational Dynamics and Excited State Dynamics -- 5.4 Outlook -- References |
| ctrlnum | (OCoLC)1288215255 |
| dewey-full | 572.86 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572.86 |
| dewey-search | 572.86 |
| dewey-sort | 3572.86 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>04993cam a2200553Mu 4500</leader><controlfield tag="001">ZDB-4-EBA-on1288215255</controlfield><controlfield tag="003">OCoLC</controlfield><controlfield tag="005">20250103110447.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr cnu---unuuu</controlfield><controlfield tag="008">211211s2022 xx o ||| 0 eng d</controlfield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">EBLCP</subfield><subfield code="b">eng</subfield><subfield code="c">EBLCP</subfield><subfield code="d">N$T</subfield><subfield code="d">OCLCO</subfield><subfield code="d">OCLCF</subfield><subfield code="d">OCLCO</subfield><subfield code="d">OCLCQ</subfield><subfield code="d">OCLCO</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">1839165596</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781839165597</subfield><subfield code="q">(electronic bk.)</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1288215255</subfield></datafield><datafield tag="050" ind1=" " ind2="4"><subfield code="a">QH465</subfield></datafield><datafield tag="082" ind1="7" ind2=" "><subfield code="a">572.86</subfield><subfield code="2">23</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">MAIN</subfield></datafield><datafield tag="245" ind1="0" ind2="0"><subfield code="a">DNA Photodamage</subfield><subfield code="h">[electronic resource] :</subfield><subfield code="b">From Light Absorption to Cellular Responses and Skin Cancer.</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="a">Cambridge :</subfield><subfield code="b">Royal Society of Chemistry,</subfield><subfield code="c">[2022]</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource (387 p.).</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="1" ind2=" "><subfield code="a">ISSN</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Description based upon print version of record.</subfield></datafield><datafield tag="505" ind1="0" ind2=" "><subfield code="a">Intro -- Half Title -- Series Title -- Title -- Copyright -- Contents -- Preface -- Chapter 1 Photoinduced Processes in DNA: Basic Theoretical and Experimental Features 1 -- 1.1 Introduction -- 1.2 A Theoretical Basis -- 1.3 Notion of Spectrum in Photobiology -- 1.3.1 Emission Spectrum of the Light Source -- 1.3.2 Absorption Spectrum -- 1.3.3 Action Spectrum -- 1.4 A Basic Introduction to Pump-probe Spectroscopies -- 1.5 Analytical Tools for the Detection of DNA Damage -- 1.5.1 Antibody-based Assays -- 1.5.2 Electrophoresis-based Assays -- 1.5.3 Chromatography-based Assays</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">1.6 Basic Biological Phenomena Associated with DNA Damage -- 1.6.1 From DNA Damage to Abnormal Proteins -- 1.6.2 Principle of DNA Repair -- Acknowledgements -- References -- Chapter 2 Photoinduced Dimerization in DNA: Singlet Excited State Reaction Paths 17 -- 2.1 Introduction -- 2.2 Pyrimidine Dimers -- 2.2.1 Mechanism of Thymine-Thymine Photodimerization -- 2.2.2 Cytosine-Thymine -- 2.3 Purine-Purine and Purine-Pyrimidine Dimers -- 2.4 Concluding Remarks -- Acknowledgements -- References -- Chapter 3 DNA Photoionization: From High to Low Energies 37 -- 3.1 Introduction</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">3.2 Energies and Quantum Yields -- 3.2.1 Direct High-energy Photoionization -- 3.2.2 Indirect Low-energy Photoionization -- 3.3 Nanosecond Flash Photolysis: Advantages and Limitations -- 3.4 Evolution of Ejected Electrons -- 3.5 Evolution of Purine Radicals -- 3.5.1 Deprotonation and Tautomerization -- 3.5.2 Radical Populations -- 3.5.3 Reaction Dynamics -- 3.6 Final Lesions -- Acknowledgements -- References -- Chapter 4 Triplet Channel Photochemistry in DNA 55 -- 4.1 Introduction -- 4.2 Formation of Nucleobase Triplet Excited State</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">4.2.1 Intrinsic Population of Nucleobase Triplet Excited State -- 4.2.2 Photosensitized Population of the Lowest Nucleobases Triplet Excited State -- 4.2.3 Triplet-Triplet Energy Transfer Within the Helix -- 4.3 Photoreactivity -- 4.3.1 Cyclobutane Pyrimidine Dimers Formation -- 4.3.2 Spore Photoproduct Formation -- 4.3.3 Formation of (6-4) Photoproduct -- 4.3.4 Reactivity from Upper Triplet Excited States -- 4.4 Conclusion -- References -- Chapter 5 Tracking Excited Electronic States in DNA From Formation to Deactivation 77 -- 5.1 Introduction</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">5.2 Excited States of DNA: Their Nature and Steady-state Spectra -- 5.2.1 Electronic Absorption Spectra and Lineshapes -- 5.2.2 Exciton Theory and Coupled Chromophores -- 5.3 Excited States of DNA: Dynamic Properties -- 5.3.1 Dynamics of Base Monomer Excited States -- 5.3.2 Dynamics of DNA Strand Excited States -- 5.3.3 Long-lived Intrastrand CT States -- 5.3.4 Formation and Decay of CT States -- 5.3.5 Excited-state Proton Transfer in Double Strands -- 5.3.6 Conformational Dynamics and Excited State Dynamics -- 5.4 Outlook -- References</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Chapter 6 Influence of DNA Structure on Lesion Formation and Repair: Role of Modelling and Simulations 105.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Written in an accessible and comprehensive manner, DNA Photodamage will appeal to all scientists working in the area whether specialists in the discipline or not and provides a complete coverage of the field, from ultrafast spectroscopy to biomedical research.</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">DNA damage.</subfield><subfield code="0">http://id.loc.gov/authorities/subjects/sh88006186</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">DNA.</subfield><subfield code="0">http://id.loc.gov/authorities/subjects/sh85037008</subfield></datafield><datafield tag="650" ind1=" " ind2="2"><subfield code="a">DNA Damage</subfield><subfield code="0">https://id.nlm.nih.gov/mesh/D004249</subfield></datafield><datafield tag="650" ind1=" " ind2="2"><subfield code="a">DNA</subfield><subfield code="0">https://id.nlm.nih.gov/mesh/D004247</subfield></datafield><datafield tag="650" ind1=" " ind2="6"><subfield code="a">ADN</subfield><subfield code="x">Lésions.</subfield></datafield><datafield tag="650" ind1=" " ind2="6"><subfield code="a">ADN.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">DNA</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">DNA damage</subfield><subfield code="2">fast</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Improta, Roberto.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Douki, Thierry.</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Print version:</subfield><subfield code="a">Improta, Roberto</subfield><subfield code="t">DNA Photodamage</subfield><subfield code="d">Cambridge : Royal Society of Chemistry,c2021</subfield><subfield code="z">9781839161964</subfield></datafield><datafield tag="830" ind1=" " ind2="0"><subfield code="a">ISSN.</subfield></datafield><datafield tag="966" ind1="4" ind2="0"><subfield code="l">DE-862</subfield><subfield code="p">ZDB-4-EBA</subfield><subfield code="q">FWS_PDA_EBA</subfield><subfield code="u">https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3117509</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="4" ind2="0"><subfield code="l">DE-863</subfield><subfield code="p">ZDB-4-EBA</subfield><subfield code="q">FWS_PDA_EBA</subfield><subfield code="u">https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3117509</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">ProQuest Ebook Central</subfield><subfield code="b">EBLB</subfield><subfield code="n">EBL6823151</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">EBSCOhost</subfield><subfield code="b">EBSC</subfield><subfield code="n">3117509</subfield></datafield><datafield tag="994" ind1=" " ind2=" "><subfield code="a">92</subfield><subfield code="b">GEBAY</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-4-EBA</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-862</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-863</subfield></datafield></record></collection> |
| id | ZDB-4-EBA-on1288215255 |
| illustrated | Not Illustrated |
| indexdate | 2025-04-11T08:47:50Z |
| institution | BVB |
| isbn | 1839165596 9781839165597 |
| language | English |
| oclc_num | 1288215255 |
| open_access_boolean | |
| owner | MAIN DE-862 DE-BY-FWS DE-863 DE-BY-FWS |
| owner_facet | MAIN DE-862 DE-BY-FWS DE-863 DE-BY-FWS |
| physical | 1 online resource (387 p.). |
| psigel | ZDB-4-EBA FWS_PDA_EBA ZDB-4-EBA |
| publishDate | 2022 |
| publishDateSearch | 2022 |
| publishDateSort | 2022 |
| publisher | Royal Society of Chemistry, |
| record_format | marc |
| series | ISSN. |
| series2 | ISSN |
| spelling | DNA Photodamage [electronic resource] : From Light Absorption to Cellular Responses and Skin Cancer. Cambridge : Royal Society of Chemistry, [2022] 1 online resource (387 p.). text txt rdacontent computer c rdamedia online resource cr rdacarrier ISSN Description based upon print version of record. Intro -- Half Title -- Series Title -- Title -- Copyright -- Contents -- Preface -- Chapter 1 Photoinduced Processes in DNA: Basic Theoretical and Experimental Features 1 -- 1.1 Introduction -- 1.2 A Theoretical Basis -- 1.3 Notion of Spectrum in Photobiology -- 1.3.1 Emission Spectrum of the Light Source -- 1.3.2 Absorption Spectrum -- 1.3.3 Action Spectrum -- 1.4 A Basic Introduction to Pump-probe Spectroscopies -- 1.5 Analytical Tools for the Detection of DNA Damage -- 1.5.1 Antibody-based Assays -- 1.5.2 Electrophoresis-based Assays -- 1.5.3 Chromatography-based Assays 1.6 Basic Biological Phenomena Associated with DNA Damage -- 1.6.1 From DNA Damage to Abnormal Proteins -- 1.6.2 Principle of DNA Repair -- Acknowledgements -- References -- Chapter 2 Photoinduced Dimerization in DNA: Singlet Excited State Reaction Paths 17 -- 2.1 Introduction -- 2.2 Pyrimidine Dimers -- 2.2.1 Mechanism of Thymine-Thymine Photodimerization -- 2.2.2 Cytosine-Thymine -- 2.3 Purine-Purine and Purine-Pyrimidine Dimers -- 2.4 Concluding Remarks -- Acknowledgements -- References -- Chapter 3 DNA Photoionization: From High to Low Energies 37 -- 3.1 Introduction 3.2 Energies and Quantum Yields -- 3.2.1 Direct High-energy Photoionization -- 3.2.2 Indirect Low-energy Photoionization -- 3.3 Nanosecond Flash Photolysis: Advantages and Limitations -- 3.4 Evolution of Ejected Electrons -- 3.5 Evolution of Purine Radicals -- 3.5.1 Deprotonation and Tautomerization -- 3.5.2 Radical Populations -- 3.5.3 Reaction Dynamics -- 3.6 Final Lesions -- Acknowledgements -- References -- Chapter 4 Triplet Channel Photochemistry in DNA 55 -- 4.1 Introduction -- 4.2 Formation of Nucleobase Triplet Excited State 4.2.1 Intrinsic Population of Nucleobase Triplet Excited State -- 4.2.2 Photosensitized Population of the Lowest Nucleobases Triplet Excited State -- 4.2.3 Triplet-Triplet Energy Transfer Within the Helix -- 4.3 Photoreactivity -- 4.3.1 Cyclobutane Pyrimidine Dimers Formation -- 4.3.2 Spore Photoproduct Formation -- 4.3.3 Formation of (6-4) Photoproduct -- 4.3.4 Reactivity from Upper Triplet Excited States -- 4.4 Conclusion -- References -- Chapter 5 Tracking Excited Electronic States in DNA From Formation to Deactivation 77 -- 5.1 Introduction 5.2 Excited States of DNA: Their Nature and Steady-state Spectra -- 5.2.1 Electronic Absorption Spectra and Lineshapes -- 5.2.2 Exciton Theory and Coupled Chromophores -- 5.3 Excited States of DNA: Dynamic Properties -- 5.3.1 Dynamics of Base Monomer Excited States -- 5.3.2 Dynamics of DNA Strand Excited States -- 5.3.3 Long-lived Intrastrand CT States -- 5.3.4 Formation and Decay of CT States -- 5.3.5 Excited-state Proton Transfer in Double Strands -- 5.3.6 Conformational Dynamics and Excited State Dynamics -- 5.4 Outlook -- References Chapter 6 Influence of DNA Structure on Lesion Formation and Repair: Role of Modelling and Simulations 105. Written in an accessible and comprehensive manner, DNA Photodamage will appeal to all scientists working in the area whether specialists in the discipline or not and provides a complete coverage of the field, from ultrafast spectroscopy to biomedical research. DNA damage. http://id.loc.gov/authorities/subjects/sh88006186 DNA. http://id.loc.gov/authorities/subjects/sh85037008 DNA Damage https://id.nlm.nih.gov/mesh/D004249 DNA https://id.nlm.nih.gov/mesh/D004247 ADN Lésions. ADN. DNA fast DNA damage fast Improta, Roberto. Douki, Thierry. Print version: Improta, Roberto DNA Photodamage Cambridge : Royal Society of Chemistry,c2021 9781839161964 ISSN. |
| spellingShingle | DNA Photodamage From Light Absorption to Cellular Responses and Skin Cancer. ISSN. Intro -- Half Title -- Series Title -- Title -- Copyright -- Contents -- Preface -- Chapter 1 Photoinduced Processes in DNA: Basic Theoretical and Experimental Features 1 -- 1.1 Introduction -- 1.2 A Theoretical Basis -- 1.3 Notion of Spectrum in Photobiology -- 1.3.1 Emission Spectrum of the Light Source -- 1.3.2 Absorption Spectrum -- 1.3.3 Action Spectrum -- 1.4 A Basic Introduction to Pump-probe Spectroscopies -- 1.5 Analytical Tools for the Detection of DNA Damage -- 1.5.1 Antibody-based Assays -- 1.5.2 Electrophoresis-based Assays -- 1.5.3 Chromatography-based Assays 1.6 Basic Biological Phenomena Associated with DNA Damage -- 1.6.1 From DNA Damage to Abnormal Proteins -- 1.6.2 Principle of DNA Repair -- Acknowledgements -- References -- Chapter 2 Photoinduced Dimerization in DNA: Singlet Excited State Reaction Paths 17 -- 2.1 Introduction -- 2.2 Pyrimidine Dimers -- 2.2.1 Mechanism of Thymine-Thymine Photodimerization -- 2.2.2 Cytosine-Thymine -- 2.3 Purine-Purine and Purine-Pyrimidine Dimers -- 2.4 Concluding Remarks -- Acknowledgements -- References -- Chapter 3 DNA Photoionization: From High to Low Energies 37 -- 3.1 Introduction 3.2 Energies and Quantum Yields -- 3.2.1 Direct High-energy Photoionization -- 3.2.2 Indirect Low-energy Photoionization -- 3.3 Nanosecond Flash Photolysis: Advantages and Limitations -- 3.4 Evolution of Ejected Electrons -- 3.5 Evolution of Purine Radicals -- 3.5.1 Deprotonation and Tautomerization -- 3.5.2 Radical Populations -- 3.5.3 Reaction Dynamics -- 3.6 Final Lesions -- Acknowledgements -- References -- Chapter 4 Triplet Channel Photochemistry in DNA 55 -- 4.1 Introduction -- 4.2 Formation of Nucleobase Triplet Excited State 4.2.1 Intrinsic Population of Nucleobase Triplet Excited State -- 4.2.2 Photosensitized Population of the Lowest Nucleobases Triplet Excited State -- 4.2.3 Triplet-Triplet Energy Transfer Within the Helix -- 4.3 Photoreactivity -- 4.3.1 Cyclobutane Pyrimidine Dimers Formation -- 4.3.2 Spore Photoproduct Formation -- 4.3.3 Formation of (6-4) Photoproduct -- 4.3.4 Reactivity from Upper Triplet Excited States -- 4.4 Conclusion -- References -- Chapter 5 Tracking Excited Electronic States in DNA From Formation to Deactivation 77 -- 5.1 Introduction 5.2 Excited States of DNA: Their Nature and Steady-state Spectra -- 5.2.1 Electronic Absorption Spectra and Lineshapes -- 5.2.2 Exciton Theory and Coupled Chromophores -- 5.3 Excited States of DNA: Dynamic Properties -- 5.3.1 Dynamics of Base Monomer Excited States -- 5.3.2 Dynamics of DNA Strand Excited States -- 5.3.3 Long-lived Intrastrand CT States -- 5.3.4 Formation and Decay of CT States -- 5.3.5 Excited-state Proton Transfer in Double Strands -- 5.3.6 Conformational Dynamics and Excited State Dynamics -- 5.4 Outlook -- References DNA damage. http://id.loc.gov/authorities/subjects/sh88006186 DNA. http://id.loc.gov/authorities/subjects/sh85037008 DNA Damage https://id.nlm.nih.gov/mesh/D004249 DNA https://id.nlm.nih.gov/mesh/D004247 ADN Lésions. ADN. DNA fast DNA damage fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh88006186 http://id.loc.gov/authorities/subjects/sh85037008 https://id.nlm.nih.gov/mesh/D004249 https://id.nlm.nih.gov/mesh/D004247 |
| title | DNA Photodamage From Light Absorption to Cellular Responses and Skin Cancer. |
| title_auth | DNA Photodamage From Light Absorption to Cellular Responses and Skin Cancer. |
| title_exact_search | DNA Photodamage From Light Absorption to Cellular Responses and Skin Cancer. |
| title_full | DNA Photodamage [electronic resource] : From Light Absorption to Cellular Responses and Skin Cancer. |
| title_fullStr | DNA Photodamage [electronic resource] : From Light Absorption to Cellular Responses and Skin Cancer. |
| title_full_unstemmed | DNA Photodamage [electronic resource] : From Light Absorption to Cellular Responses and Skin Cancer. |
| title_short | DNA Photodamage |
| title_sort | dna photodamage from light absorption to cellular responses and skin cancer |
| title_sub | From Light Absorption to Cellular Responses and Skin Cancer. |
| topic | DNA damage. http://id.loc.gov/authorities/subjects/sh88006186 DNA. http://id.loc.gov/authorities/subjects/sh85037008 DNA Damage https://id.nlm.nih.gov/mesh/D004249 DNA https://id.nlm.nih.gov/mesh/D004247 ADN Lésions. ADN. DNA fast DNA damage fast |
| topic_facet | DNA damage. DNA. DNA Damage DNA ADN Lésions. ADN. DNA damage |
| work_keys_str_mv | AT improtaroberto dnaphotodamagefromlightabsorptiontocellularresponsesandskincancer AT doukithierry dnaphotodamagefromlightabsorptiontocellularresponsesandskincancer |