DNA Photodamage: From Light Absorption to Cellular Responses and Skin Cancer.
Written in an accessible and comprehensive manner, DNA Photodamage will appeal to all scientists working in the area whether specialists in the discipline or not and provides a complete coverage of the field, from ultrafast spectroscopy to biomedical research.
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge :
Royal Society of Chemistry,
[2022]
|
| Schriftenreihe: | ISSN.
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | Written in an accessible and comprehensive manner, DNA Photodamage will appeal to all scientists working in the area whether specialists in the discipline or not and provides a complete coverage of the field, from ultrafast spectroscopy to biomedical research. |
| Beschreibung: | Description based upon print version of record. Chapter 6 Influence of DNA Structure on Lesion Formation and Repair: Role of Modelling and Simulations 105. |
| Beschreibung: | 1 online resource (387 p.). |
| ISBN: | 1839165596 9781839165597 |
Internformat
MARC
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| 245 | 0 | 0 | |a DNA Photodamage |h [electronic resource] : |b From Light Absorption to Cellular Responses and Skin Cancer. |
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| 300 | |a 1 online resource (387 p.). | ||
| 490 | 1 | |a ISSN | |
| 500 | |a Description based upon print version of record. | ||
| 505 | 0 | |a Intro -- Half Title -- Series Title -- Title -- Copyright -- Contents -- Preface -- Chapter 1 Photoinduced Processes in DNA: Basic Theoretical and Experimental Features 1 -- 1.1 Introduction -- 1.2 A Theoretical Basis -- 1.3 Notion of Spectrum in Photobiology -- 1.3.1 Emission Spectrum of the Light Source -- 1.3.2 Absorption Spectrum -- 1.3.3 Action Spectrum -- 1.4 A Basic Introduction to Pump-probe Spectroscopies -- 1.5 Analytical Tools for the Detection of DNA Damage -- 1.5.1 Antibody-based Assays -- 1.5.2 Electrophoresis-based Assays -- 1.5.3 Chromatography-based Assays | |
| 505 | 8 | |a 1.6 Basic Biological Phenomena Associated with DNA Damage -- 1.6.1 From DNA Damage to Abnormal Proteins -- 1.6.2 Principle of DNA Repair -- Acknowledgements -- References -- Chapter 2 Photoinduced Dimerization in DNA: Singlet Excited State Reaction Paths 17 -- 2.1 Introduction -- 2.2 Pyrimidine Dimers -- 2.2.1 Mechanism of Thymine-Thymine Photodimerization -- 2.2.2 Cytosine-Thymine -- 2.3 Purine-Purine and Purine-Pyrimidine Dimers -- 2.4 Concluding Remarks -- Acknowledgements -- References -- Chapter 3 DNA Photoionization: From High to Low Energies 37 -- 3.1 Introduction | |
| 505 | 8 | |a 3.2 Energies and Quantum Yields -- 3.2.1 Direct High-energy Photoionization -- 3.2.2 Indirect Low-energy Photoionization -- 3.3 Nanosecond Flash Photolysis: Advantages and Limitations -- 3.4 Evolution of Ejected Electrons -- 3.5 Evolution of Purine Radicals -- 3.5.1 Deprotonation and Tautomerization -- 3.5.2 Radical Populations -- 3.5.3 Reaction Dynamics -- 3.6 Final Lesions -- Acknowledgements -- References -- Chapter 4 Triplet Channel Photochemistry in DNA 55 -- 4.1 Introduction -- 4.2 Formation of Nucleobase Triplet Excited State | |
| 505 | 8 | |a 4.2.1 Intrinsic Population of Nucleobase Triplet Excited State -- 4.2.2 Photosensitized Population of the Lowest Nucleobases Triplet Excited State -- 4.2.3 Triplet-Triplet Energy Transfer Within the Helix -- 4.3 Photoreactivity -- 4.3.1 Cyclobutane Pyrimidine Dimers Formation -- 4.3.2 Spore Photoproduct Formation -- 4.3.3 Formation of (6-4) Photoproduct -- 4.3.4 Reactivity from Upper Triplet Excited States -- 4.4 Conclusion -- References -- Chapter 5 Tracking Excited Electronic States in DNA From Formation to Deactivation 77 -- 5.1 Introduction | |
| 505 | 8 | |a 5.2 Excited States of DNA: Their Nature and Steady-state Spectra -- 5.2.1 Electronic Absorption Spectra and Lineshapes -- 5.2.2 Exciton Theory and Coupled Chromophores -- 5.3 Excited States of DNA: Dynamic Properties -- 5.3.1 Dynamics of Base Monomer Excited States -- 5.3.2 Dynamics of DNA Strand Excited States -- 5.3.3 Long-lived Intrastrand CT States -- 5.3.4 Formation and Decay of CT States -- 5.3.5 Excited-state Proton Transfer in Double Strands -- 5.3.6 Conformational Dynamics and Excited State Dynamics -- 5.4 Outlook -- References | |
| 500 | |a Chapter 6 Influence of DNA Structure on Lesion Formation and Repair: Role of Modelling and Simulations 105. | ||
| 520 | |a Written in an accessible and comprehensive manner, DNA Photodamage will appeal to all scientists working in the area whether specialists in the discipline or not and provides a complete coverage of the field, from ultrafast spectroscopy to biomedical research. | ||
| 650 | 0 | |a DNA damage. |0 http://id.loc.gov/authorities/subjects/sh88006186 | |
| 650 | 0 | |a DNA. |0 http://id.loc.gov/authorities/subjects/sh85037008 | |
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| 650 | 2 | |a DNA |0 https://id.nlm.nih.gov/mesh/D004247 | |
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| 650 | 7 | |a DNA damage |2 fast | |
| 700 | 1 | |a Improta, Roberto. | |
| 700 | 1 | |a Douki, Thierry. | |
| 776 | 0 | 8 | |i Print version: |a Improta, Roberto |t DNA Photodamage |d Cambridge : Royal Society of Chemistry,c2021 |z 9781839161964 |
| 830 | 0 | |a ISSN. | |
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| contents | Intro -- Half Title -- Series Title -- Title -- Copyright -- Contents -- Preface -- Chapter 1 Photoinduced Processes in DNA: Basic Theoretical and Experimental Features 1 -- 1.1 Introduction -- 1.2 A Theoretical Basis -- 1.3 Notion of Spectrum in Photobiology -- 1.3.1 Emission Spectrum of the Light Source -- 1.3.2 Absorption Spectrum -- 1.3.3 Action Spectrum -- 1.4 A Basic Introduction to Pump-probe Spectroscopies -- 1.5 Analytical Tools for the Detection of DNA Damage -- 1.5.1 Antibody-based Assays -- 1.5.2 Electrophoresis-based Assays -- 1.5.3 Chromatography-based Assays 1.6 Basic Biological Phenomena Associated with DNA Damage -- 1.6.1 From DNA Damage to Abnormal Proteins -- 1.6.2 Principle of DNA Repair -- Acknowledgements -- References -- Chapter 2 Photoinduced Dimerization in DNA: Singlet Excited State Reaction Paths 17 -- 2.1 Introduction -- 2.2 Pyrimidine Dimers -- 2.2.1 Mechanism of Thymine-Thymine Photodimerization -- 2.2.2 Cytosine-Thymine -- 2.3 Purine-Purine and Purine-Pyrimidine Dimers -- 2.4 Concluding Remarks -- Acknowledgements -- References -- Chapter 3 DNA Photoionization: From High to Low Energies 37 -- 3.1 Introduction 3.2 Energies and Quantum Yields -- 3.2.1 Direct High-energy Photoionization -- 3.2.2 Indirect Low-energy Photoionization -- 3.3 Nanosecond Flash Photolysis: Advantages and Limitations -- 3.4 Evolution of Ejected Electrons -- 3.5 Evolution of Purine Radicals -- 3.5.1 Deprotonation and Tautomerization -- 3.5.2 Radical Populations -- 3.5.3 Reaction Dynamics -- 3.6 Final Lesions -- Acknowledgements -- References -- Chapter 4 Triplet Channel Photochemistry in DNA 55 -- 4.1 Introduction -- 4.2 Formation of Nucleobase Triplet Excited State 4.2.1 Intrinsic Population of Nucleobase Triplet Excited State -- 4.2.2 Photosensitized Population of the Lowest Nucleobases Triplet Excited State -- 4.2.3 Triplet-Triplet Energy Transfer Within the Helix -- 4.3 Photoreactivity -- 4.3.1 Cyclobutane Pyrimidine Dimers Formation -- 4.3.2 Spore Photoproduct Formation -- 4.3.3 Formation of (6-4) Photoproduct -- 4.3.4 Reactivity from Upper Triplet Excited States -- 4.4 Conclusion -- References -- Chapter 5 Tracking Excited Electronic States in DNA From Formation to Deactivation 77 -- 5.1 Introduction 5.2 Excited States of DNA: Their Nature and Steady-state Spectra -- 5.2.1 Electronic Absorption Spectra and Lineshapes -- 5.2.2 Exciton Theory and Coupled Chromophores -- 5.3 Excited States of DNA: Dynamic Properties -- 5.3.1 Dynamics of Base Monomer Excited States -- 5.3.2 Dynamics of DNA Strand Excited States -- 5.3.3 Long-lived Intrastrand CT States -- 5.3.4 Formation and Decay of CT States -- 5.3.5 Excited-state Proton Transfer in Double Strands -- 5.3.6 Conformational Dynamics and Excited State Dynamics -- 5.4 Outlook -- References |
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| id | ZDB-4-EBA-on1288215255 |
| illustrated | Not Illustrated |
| indexdate | 2024-11-27T13:30:27Z |
| institution | BVB |
| isbn | 1839165596 9781839165597 |
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| series2 | ISSN |
| spelling | DNA Photodamage [electronic resource] : From Light Absorption to Cellular Responses and Skin Cancer. Cambridge : Royal Society of Chemistry, [2022] 1 online resource (387 p.). ISSN Description based upon print version of record. Intro -- Half Title -- Series Title -- Title -- Copyright -- Contents -- Preface -- Chapter 1 Photoinduced Processes in DNA: Basic Theoretical and Experimental Features 1 -- 1.1 Introduction -- 1.2 A Theoretical Basis -- 1.3 Notion of Spectrum in Photobiology -- 1.3.1 Emission Spectrum of the Light Source -- 1.3.2 Absorption Spectrum -- 1.3.3 Action Spectrum -- 1.4 A Basic Introduction to Pump-probe Spectroscopies -- 1.5 Analytical Tools for the Detection of DNA Damage -- 1.5.1 Antibody-based Assays -- 1.5.2 Electrophoresis-based Assays -- 1.5.3 Chromatography-based Assays 1.6 Basic Biological Phenomena Associated with DNA Damage -- 1.6.1 From DNA Damage to Abnormal Proteins -- 1.6.2 Principle of DNA Repair -- Acknowledgements -- References -- Chapter 2 Photoinduced Dimerization in DNA: Singlet Excited State Reaction Paths 17 -- 2.1 Introduction -- 2.2 Pyrimidine Dimers -- 2.2.1 Mechanism of Thymine-Thymine Photodimerization -- 2.2.2 Cytosine-Thymine -- 2.3 Purine-Purine and Purine-Pyrimidine Dimers -- 2.4 Concluding Remarks -- Acknowledgements -- References -- Chapter 3 DNA Photoionization: From High to Low Energies 37 -- 3.1 Introduction 3.2 Energies and Quantum Yields -- 3.2.1 Direct High-energy Photoionization -- 3.2.2 Indirect Low-energy Photoionization -- 3.3 Nanosecond Flash Photolysis: Advantages and Limitations -- 3.4 Evolution of Ejected Electrons -- 3.5 Evolution of Purine Radicals -- 3.5.1 Deprotonation and Tautomerization -- 3.5.2 Radical Populations -- 3.5.3 Reaction Dynamics -- 3.6 Final Lesions -- Acknowledgements -- References -- Chapter 4 Triplet Channel Photochemistry in DNA 55 -- 4.1 Introduction -- 4.2 Formation of Nucleobase Triplet Excited State 4.2.1 Intrinsic Population of Nucleobase Triplet Excited State -- 4.2.2 Photosensitized Population of the Lowest Nucleobases Triplet Excited State -- 4.2.3 Triplet-Triplet Energy Transfer Within the Helix -- 4.3 Photoreactivity -- 4.3.1 Cyclobutane Pyrimidine Dimers Formation -- 4.3.2 Spore Photoproduct Formation -- 4.3.3 Formation of (6-4) Photoproduct -- 4.3.4 Reactivity from Upper Triplet Excited States -- 4.4 Conclusion -- References -- Chapter 5 Tracking Excited Electronic States in DNA From Formation to Deactivation 77 -- 5.1 Introduction 5.2 Excited States of DNA: Their Nature and Steady-state Spectra -- 5.2.1 Electronic Absorption Spectra and Lineshapes -- 5.2.2 Exciton Theory and Coupled Chromophores -- 5.3 Excited States of DNA: Dynamic Properties -- 5.3.1 Dynamics of Base Monomer Excited States -- 5.3.2 Dynamics of DNA Strand Excited States -- 5.3.3 Long-lived Intrastrand CT States -- 5.3.4 Formation and Decay of CT States -- 5.3.5 Excited-state Proton Transfer in Double Strands -- 5.3.6 Conformational Dynamics and Excited State Dynamics -- 5.4 Outlook -- References Chapter 6 Influence of DNA Structure on Lesion Formation and Repair: Role of Modelling and Simulations 105. Written in an accessible and comprehensive manner, DNA Photodamage will appeal to all scientists working in the area whether specialists in the discipline or not and provides a complete coverage of the field, from ultrafast spectroscopy to biomedical research. DNA damage. http://id.loc.gov/authorities/subjects/sh88006186 DNA. http://id.loc.gov/authorities/subjects/sh85037008 DNA Damage https://id.nlm.nih.gov/mesh/D004249 DNA https://id.nlm.nih.gov/mesh/D004247 ADN Lésions. ADN. DNA fast DNA damage fast Improta, Roberto. Douki, Thierry. Print version: Improta, Roberto DNA Photodamage Cambridge : Royal Society of Chemistry,c2021 9781839161964 ISSN. FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3117509 Volltext |
| spellingShingle | DNA Photodamage From Light Absorption to Cellular Responses and Skin Cancer. ISSN. Intro -- Half Title -- Series Title -- Title -- Copyright -- Contents -- Preface -- Chapter 1 Photoinduced Processes in DNA: Basic Theoretical and Experimental Features 1 -- 1.1 Introduction -- 1.2 A Theoretical Basis -- 1.3 Notion of Spectrum in Photobiology -- 1.3.1 Emission Spectrum of the Light Source -- 1.3.2 Absorption Spectrum -- 1.3.3 Action Spectrum -- 1.4 A Basic Introduction to Pump-probe Spectroscopies -- 1.5 Analytical Tools for the Detection of DNA Damage -- 1.5.1 Antibody-based Assays -- 1.5.2 Electrophoresis-based Assays -- 1.5.3 Chromatography-based Assays 1.6 Basic Biological Phenomena Associated with DNA Damage -- 1.6.1 From DNA Damage to Abnormal Proteins -- 1.6.2 Principle of DNA Repair -- Acknowledgements -- References -- Chapter 2 Photoinduced Dimerization in DNA: Singlet Excited State Reaction Paths 17 -- 2.1 Introduction -- 2.2 Pyrimidine Dimers -- 2.2.1 Mechanism of Thymine-Thymine Photodimerization -- 2.2.2 Cytosine-Thymine -- 2.3 Purine-Purine and Purine-Pyrimidine Dimers -- 2.4 Concluding Remarks -- Acknowledgements -- References -- Chapter 3 DNA Photoionization: From High to Low Energies 37 -- 3.1 Introduction 3.2 Energies and Quantum Yields -- 3.2.1 Direct High-energy Photoionization -- 3.2.2 Indirect Low-energy Photoionization -- 3.3 Nanosecond Flash Photolysis: Advantages and Limitations -- 3.4 Evolution of Ejected Electrons -- 3.5 Evolution of Purine Radicals -- 3.5.1 Deprotonation and Tautomerization -- 3.5.2 Radical Populations -- 3.5.3 Reaction Dynamics -- 3.6 Final Lesions -- Acknowledgements -- References -- Chapter 4 Triplet Channel Photochemistry in DNA 55 -- 4.1 Introduction -- 4.2 Formation of Nucleobase Triplet Excited State 4.2.1 Intrinsic Population of Nucleobase Triplet Excited State -- 4.2.2 Photosensitized Population of the Lowest Nucleobases Triplet Excited State -- 4.2.3 Triplet-Triplet Energy Transfer Within the Helix -- 4.3 Photoreactivity -- 4.3.1 Cyclobutane Pyrimidine Dimers Formation -- 4.3.2 Spore Photoproduct Formation -- 4.3.3 Formation of (6-4) Photoproduct -- 4.3.4 Reactivity from Upper Triplet Excited States -- 4.4 Conclusion -- References -- Chapter 5 Tracking Excited Electronic States in DNA From Formation to Deactivation 77 -- 5.1 Introduction 5.2 Excited States of DNA: Their Nature and Steady-state Spectra -- 5.2.1 Electronic Absorption Spectra and Lineshapes -- 5.2.2 Exciton Theory and Coupled Chromophores -- 5.3 Excited States of DNA: Dynamic Properties -- 5.3.1 Dynamics of Base Monomer Excited States -- 5.3.2 Dynamics of DNA Strand Excited States -- 5.3.3 Long-lived Intrastrand CT States -- 5.3.4 Formation and Decay of CT States -- 5.3.5 Excited-state Proton Transfer in Double Strands -- 5.3.6 Conformational Dynamics and Excited State Dynamics -- 5.4 Outlook -- References DNA damage. http://id.loc.gov/authorities/subjects/sh88006186 DNA. http://id.loc.gov/authorities/subjects/sh85037008 DNA Damage https://id.nlm.nih.gov/mesh/D004249 DNA https://id.nlm.nih.gov/mesh/D004247 ADN Lésions. ADN. DNA fast DNA damage fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh88006186 http://id.loc.gov/authorities/subjects/sh85037008 https://id.nlm.nih.gov/mesh/D004249 https://id.nlm.nih.gov/mesh/D004247 |
| title | DNA Photodamage From Light Absorption to Cellular Responses and Skin Cancer. |
| title_auth | DNA Photodamage From Light Absorption to Cellular Responses and Skin Cancer. |
| title_exact_search | DNA Photodamage From Light Absorption to Cellular Responses and Skin Cancer. |
| title_full | DNA Photodamage [electronic resource] : From Light Absorption to Cellular Responses and Skin Cancer. |
| title_fullStr | DNA Photodamage [electronic resource] : From Light Absorption to Cellular Responses and Skin Cancer. |
| title_full_unstemmed | DNA Photodamage [electronic resource] : From Light Absorption to Cellular Responses and Skin Cancer. |
| title_short | DNA Photodamage |
| title_sort | dna photodamage from light absorption to cellular responses and skin cancer |
| title_sub | From Light Absorption to Cellular Responses and Skin Cancer. |
| topic | DNA damage. http://id.loc.gov/authorities/subjects/sh88006186 DNA. http://id.loc.gov/authorities/subjects/sh85037008 DNA Damage https://id.nlm.nih.gov/mesh/D004249 DNA https://id.nlm.nih.gov/mesh/D004247 ADN Lésions. ADN. DNA fast DNA damage fast |
| topic_facet | DNA damage. DNA. DNA Damage DNA ADN Lésions. ADN. DNA damage |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3117509 |
| work_keys_str_mv | AT improtaroberto dnaphotodamagefromlightabsorptiontocellularresponsesandskincancer AT doukithierry dnaphotodamagefromlightabsorptiontocellularresponsesandskincancer |