Superparamagnetic iron oxide nanoparticles :: synthesis, surface engineering, cytotoxicity, and biomedical applications /
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York :
Nova Science Publishers,
[2011]
|
| Schriftenreihe: | Nanotechnology science and technology series.
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | 1 online resource. |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9781617286315 1617286311 |
Internformat
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| 245 | 0 | 0 | |a Superparamagnetic iron oxide nanoparticles : |b synthesis, surface engineering, cytotoxicity, and biomedical applications / |c Morteza Mahmoudi ... [and others]. |
| 264 | 1 | |a New York : |b Nova Science Publishers, |c [2011] | |
| 300 | |a 1 online resource. | ||
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| 546 | |a English. | ||
| 505 | 0 | |a Intro -- SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES: SYNTHESIS, SURFACE ENGINEERING, CYTOTOXICITY AND BIOMEDICAL APPLICATIONS -- SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES: SYNTHESIS, SURFACE ENGINEERING, CYTOTOXICITY AND BIOMEDICAL APPLICATIONS -- LIBRARY OF CONGRESS CATALOGING-IN-PUBLICATION DATA -- DEDICATION -- ABOUT THE AUTHORS -- CONTENTS -- PREFACE -- Chapter 1 INTRODUCTORY TO THE BOOK -- 1.1. SEMICONDUCTING NANOPARTICLES -- 1.2. IRON OXIDE NANOPARTICLES -- 1.3. BIOMINERALIZATION -- 1.4. TYPES OF MAGNETIC IRON OXIDES -- 1.5. SYNTHESIS OF SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES (SPIONS): CHEMICAL COPRECIPITATION -- 1.6. DESIGN OF EXPERIMENTS (DOE) FOR SYNTHESIS OF SPIONS -- REFERENCES -- Chapter 2 SYNTHESIS OF SPIONS -- 2.1. NUCLEATION OF NANOPARTICLES -- 2.2. SYNTHESIS METHODS -- 2.2.1. Chemical Methods -- 2.2.1.1. Co-precipitation -- 2.2.1.2. Microemulsions -- 2.2.1.3. Hydrothermal -- 2.2.1.4. Thermal Decomposition -- 2.2.1.5. Sol-gel -- 2.2.1.6. Polyol -- 2.2.1.7. Sonochemical -- 2.2.1.8. Electrochemical Deposition -- 2.2.2. Physical Methods -- 2.2.2.1. Flow Injection -- 2.2.2.2. Aerosol/Vapor -- 2.2.2.3. Pulsed Laser Ablation -- 2.2.2.4. Laser Induced Pyrolysis -- 2.2.2.5. Powder Ball Milling -- 2.2.3. Biological/ Bio-mineralization -- REFERENCES -- Chapter 3 APPLICATION OF STATISTICAL TECHNIQUES -- 3.1. THE TWO SAMPLE T-TEST -- 3.2. HYPOTHESIS TESTING FOR OUTLIER DETECTION -- GRUBBS' TEST -- 3.3. DESIGN OF EXPERIMENTS -- Remark: How to Perform the Analysis with More than Two Factors, Two Levels? -- 3.3.1. Checking Model Assumptions: Effect of Potentially Outlying Observations -- REFERENCES -- Chapter 4 COATINGS OF SPIONS -- 4.1. COLLOIDAL STABILITY OF SPIONS -- 4.2. POLYMERIC COATING -- 4.2.1. Polyethylene Glycol -- 4.2.2. Polyethylene Glycol Fumarate -- 4.2.3. Polyvinyl Alcohol -- 4.2.4. Polyacrylic Acid. | |
| 505 | 8 | |a 4.2.5. Poly(N-isopropylacrylamide) -- 4.2.6. Dextran -- 4.2.7. Poly(D, L-lactide) -- 4.2.8. Poly(D, L-lactide-co-glycolide) -- 4.2.9. Alginate -- 4.2.10. Chitosan and Polyethylenimine -- 4.3. NON-POLYMERIC COATING -- 4.3.1. Gold -- 4.3.2. Silica -- 4.4. FUNCTIONALIZATION OF SPIONS -- REFERENCES -- Chapter 5 CYTOTOXICITY OF SPIONS -- 5.1. BIOCOMPATIBILITY VERSUS TOXICITY -- 5.1.1. Biocompatibility -- 5.1.2. Cytotoxicity -- 5.2. IN VITRO TOXICITY ASSAYS -- 5.2.1. Metabolic Activity -- 5.2.1.1. MTT Assay -- 5.2.1.1.1. Modification of MTT Method -- 5.2.1.2. MTS and XTT Assays -- 5.2.1.2.1. MTS Assay -- 5.2.1.2.2. XTT Assay -- 5.2.1.3. Redox Assay -- 5.2.1.4. Adenosine Triphosphate Assay -- 5.12.1.5. Cytochrome C Assay -- 5.2.1.6. Nitroblue Tetrazolium (NBT) Assay -- 5.2.1.7. WST Assay -- 5.2.2. Membrane Integrity -- 5.2.2.1. LDH Assay -- 5.2.2.2. The Calcein AM, Live/Dead and Ethidium Homodimer Assay -- 5.2.2.3. Dye Assays -- 5.2.2.3.1. Erythrosine B (EB) Assay -- 5.2.2.3.2. Propidium Iodide (PI) Assay -- 5.2.2.3.3. Neutral Red (NR) Assay -- 5.2.2.3.4. Bromodeoxyuridine (BrdU) Assay -- 5.2.2.3.5. Trypan Blue (TB) Assay -- 5.2.2.3.6. DNA Hoechst Assay -- 5.2.2.3.7. Other Dye Assays -- 5.2.3. Cell Proliferation Assay -- 5.2.3.1. Cell Cycle Assay -- 5.2.3.2. [3H] Thymidine Incorporation Assay -- 5.2.4. Apoptosis Detection -- 5.2.4.1. Flow Cytometry -- 5.2.4.2. Comet Assay -- 5.3. IN VIVO TOXICITY -- 5.4. PHARMACOKINETICS AND BIODISTRIBUTION -- REFERENCES -- Chapter 6 APPLICATION OF SPIONS* -- 6.1. SPIONS AS MAGNETIC RESONANCE IMAGING CONTRAST AGENT -- Introduction -- Paramagnetic Agents -- Superparamagnetic Agents -- Current Clinical Use of (U)SPIONs as Contrast Agents -- Oral Contrast Agents -- Injectable Contrast Agents -- Ferumoxides (Feridex I.V./Endorem) -- Ferucarbotran/SHU555A (Resovist/Cliavist) -- Ferumoxtran-10 (USPIO) (Combidex/Senerem). | |
| 505 | 8 | |a PEG-feron (Feruglose/Clariscan) -- Ferucarbotran (USPIO)/SHU555C (Supravist) -- Ferumoxytol (USPIO) (Feraheme) -- 6.2. SPIONS FOR MAGNETIC LABELING OF CELLS -- Introduction -- SPIONs and its Modification for Labeling -- Transfection Agents Mediated Modification of SPIONs for Cell Labeling -- Optimization of Cell Labeling with Simple Incubation -- Assay to Determine the Toxicity of Labeling -- 6.3. SPIONS AND MAGNETICALLY LABELED CELLS FOR MULTIMODAL REGIMENS -- SPIONs for Multimodal Imaging -- Cells for Multimodal Imaging -- 6.4. SPIONS AS DRUG DELIVERY VEHICLES -- Introduction -- Active Targeting Using Ligand Substrate Mechanisms, Antigen-Antibody or Receptors -- Enhanced Permeability Retention (EPR) Effect -- Convection-Enhanced Delivery -- Magnet Activated Delivery -- Drug Delivery by Direct Injection -- 6.5. SPIONS FOR HYPERTHERMIA TREATMENT -- 6.6. SPIONS FOR ENHANCED TRANSFECTION OF DNA (MAGNETOFECTION) -- 6.7. SPIONS FOR CELL/PROTEIN SEPARATION -- 6.8. SPIONS AS CATALYST -- 6.9. SPIONS FOR TISSUE REPAIR -- REFERENCES -- INDEX. | |
| 650 | 0 | |a Nanomedicine. |0 http://id.loc.gov/authorities/subjects/sh2007008651 | |
| 650 | 0 | |a Ferric oxide |x Magnetic properties. | |
| 650 | 0 | |a Nanoparticles. |0 http://id.loc.gov/authorities/subjects/sh85089689 | |
| 650 | 2 | |a Nanoparticles |0 https://id.nlm.nih.gov/mesh/D053758 | |
| 650 | 2 | |a Nanomedicine |0 https://id.nlm.nih.gov/mesh/D050997 | |
| 650 | 6 | |a Nanoparticules. | |
| 650 | 6 | |a Nanomédecine. | |
| 650 | 7 | |a MEDICAL |x Instruments & Supplies. |2 bisacsh | |
| 650 | 7 | |a Nanomedicine |2 fast | |
| 650 | 7 | |a Nanoparticles |2 fast | |
| 700 | 1 | |a Mahmoudi, Morteza, |d 1979- |1 https://id.oclc.org/worldcat/entity/E39PBJjhC7CvHKJGbCfhBvBByd |0 http://id.loc.gov/authorities/names/n2010062346 | |
| 758 | |i has work: |a Superparamagnetic iron oxide nanoparticles (Text) |1 https://id.oclc.org/worldcat/entity/E39PCFRKpPwpfvp63jd64CdwBX |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |t Superparamagnetic iron oxide nanoparticles |d New York : Nova Science Publishers, c2011. |z 9781616689643 (hardcover) |w (DLC) 2010036438 |
| 830 | 0 | |a Nanotechnology science and technology series. |0 http://id.loc.gov/authorities/names/no2009109464 | |
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Datensatz im Suchindex
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| contents | Intro -- SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES: SYNTHESIS, SURFACE ENGINEERING, CYTOTOXICITY AND BIOMEDICAL APPLICATIONS -- SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES: SYNTHESIS, SURFACE ENGINEERING, CYTOTOXICITY AND BIOMEDICAL APPLICATIONS -- LIBRARY OF CONGRESS CATALOGING-IN-PUBLICATION DATA -- DEDICATION -- ABOUT THE AUTHORS -- CONTENTS -- PREFACE -- Chapter 1 INTRODUCTORY TO THE BOOK -- 1.1. SEMICONDUCTING NANOPARTICLES -- 1.2. IRON OXIDE NANOPARTICLES -- 1.3. BIOMINERALIZATION -- 1.4. TYPES OF MAGNETIC IRON OXIDES -- 1.5. SYNTHESIS OF SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES (SPIONS): CHEMICAL COPRECIPITATION -- 1.6. DESIGN OF EXPERIMENTS (DOE) FOR SYNTHESIS OF SPIONS -- REFERENCES -- Chapter 2 SYNTHESIS OF SPIONS -- 2.1. NUCLEATION OF NANOPARTICLES -- 2.2. SYNTHESIS METHODS -- 2.2.1. Chemical Methods -- 2.2.1.1. Co-precipitation -- 2.2.1.2. Microemulsions -- 2.2.1.3. Hydrothermal -- 2.2.1.4. Thermal Decomposition -- 2.2.1.5. Sol-gel -- 2.2.1.6. Polyol -- 2.2.1.7. Sonochemical -- 2.2.1.8. Electrochemical Deposition -- 2.2.2. Physical Methods -- 2.2.2.1. Flow Injection -- 2.2.2.2. Aerosol/Vapor -- 2.2.2.3. Pulsed Laser Ablation -- 2.2.2.4. Laser Induced Pyrolysis -- 2.2.2.5. Powder Ball Milling -- 2.2.3. Biological/ Bio-mineralization -- REFERENCES -- Chapter 3 APPLICATION OF STATISTICAL TECHNIQUES -- 3.1. THE TWO SAMPLE T-TEST -- 3.2. HYPOTHESIS TESTING FOR OUTLIER DETECTION -- GRUBBS' TEST -- 3.3. DESIGN OF EXPERIMENTS -- Remark: How to Perform the Analysis with More than Two Factors, Two Levels? -- 3.3.1. Checking Model Assumptions: Effect of Potentially Outlying Observations -- REFERENCES -- Chapter 4 COATINGS OF SPIONS -- 4.1. COLLOIDAL STABILITY OF SPIONS -- 4.2. POLYMERIC COATING -- 4.2.1. Polyethylene Glycol -- 4.2.2. Polyethylene Glycol Fumarate -- 4.2.3. Polyvinyl Alcohol -- 4.2.4. Polyacrylic Acid. 4.2.5. Poly(N-isopropylacrylamide) -- 4.2.6. Dextran -- 4.2.7. Poly(D, L-lactide) -- 4.2.8. Poly(D, L-lactide-co-glycolide) -- 4.2.9. Alginate -- 4.2.10. Chitosan and Polyethylenimine -- 4.3. NON-POLYMERIC COATING -- 4.3.1. Gold -- 4.3.2. Silica -- 4.4. FUNCTIONALIZATION OF SPIONS -- REFERENCES -- Chapter 5 CYTOTOXICITY OF SPIONS -- 5.1. BIOCOMPATIBILITY VERSUS TOXICITY -- 5.1.1. Biocompatibility -- 5.1.2. Cytotoxicity -- 5.2. IN VITRO TOXICITY ASSAYS -- 5.2.1. Metabolic Activity -- 5.2.1.1. MTT Assay -- 5.2.1.1.1. Modification of MTT Method -- 5.2.1.2. MTS and XTT Assays -- 5.2.1.2.1. MTS Assay -- 5.2.1.2.2. XTT Assay -- 5.2.1.3. Redox Assay -- 5.2.1.4. Adenosine Triphosphate Assay -- 5.12.1.5. Cytochrome C Assay -- 5.2.1.6. Nitroblue Tetrazolium (NBT) Assay -- 5.2.1.7. WST Assay -- 5.2.2. Membrane Integrity -- 5.2.2.1. LDH Assay -- 5.2.2.2. The Calcein AM, Live/Dead and Ethidium Homodimer Assay -- 5.2.2.3. Dye Assays -- 5.2.2.3.1. Erythrosine B (EB) Assay -- 5.2.2.3.2. Propidium Iodide (PI) Assay -- 5.2.2.3.3. Neutral Red (NR) Assay -- 5.2.2.3.4. Bromodeoxyuridine (BrdU) Assay -- 5.2.2.3.5. Trypan Blue (TB) Assay -- 5.2.2.3.6. DNA Hoechst Assay -- 5.2.2.3.7. Other Dye Assays -- 5.2.3. Cell Proliferation Assay -- 5.2.3.1. Cell Cycle Assay -- 5.2.3.2. [3H] Thymidine Incorporation Assay -- 5.2.4. Apoptosis Detection -- 5.2.4.1. Flow Cytometry -- 5.2.4.2. Comet Assay -- 5.3. IN VIVO TOXICITY -- 5.4. PHARMACOKINETICS AND BIODISTRIBUTION -- REFERENCES -- Chapter 6 APPLICATION OF SPIONS* -- 6.1. SPIONS AS MAGNETIC RESONANCE IMAGING CONTRAST AGENT -- Introduction -- Paramagnetic Agents -- Superparamagnetic Agents -- Current Clinical Use of (U)SPIONs as Contrast Agents -- Oral Contrast Agents -- Injectable Contrast Agents -- Ferumoxides (Feridex I.V./Endorem) -- Ferucarbotran/SHU555A (Resovist/Cliavist) -- Ferumoxtran-10 (USPIO) (Combidex/Senerem). PEG-feron (Feruglose/Clariscan) -- Ferucarbotran (USPIO)/SHU555C (Supravist) -- Ferumoxytol (USPIO) (Feraheme) -- 6.2. SPIONS FOR MAGNETIC LABELING OF CELLS -- Introduction -- SPIONs and its Modification for Labeling -- Transfection Agents Mediated Modification of SPIONs for Cell Labeling -- Optimization of Cell Labeling with Simple Incubation -- Assay to Determine the Toxicity of Labeling -- 6.3. SPIONS AND MAGNETICALLY LABELED CELLS FOR MULTIMODAL REGIMENS -- SPIONs for Multimodal Imaging -- Cells for Multimodal Imaging -- 6.4. SPIONS AS DRUG DELIVERY VEHICLES -- Introduction -- Active Targeting Using Ligand Substrate Mechanisms, Antigen-Antibody or Receptors -- Enhanced Permeability Retention (EPR) Effect -- Convection-Enhanced Delivery -- Magnet Activated Delivery -- Drug Delivery by Direct Injection -- 6.5. SPIONS FOR HYPERTHERMIA TREATMENT -- 6.6. SPIONS FOR ENHANCED TRANSFECTION OF DNA (MAGNETOFECTION) -- 6.7. SPIONS FOR CELL/PROTEIN SEPARATION -- 6.8. SPIONS AS CATALYST -- 6.9. SPIONS FOR TISSUE REPAIR -- REFERENCES -- INDEX. |
| ctrlnum | (OCoLC)1162020434 |
| dewey-full | 610.28/4 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 610 - Medicine and health |
| dewey-raw | 610.28/4 |
| dewey-search | 610.28/4 |
| dewey-sort | 3610.28 14 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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[and others].</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">New York :</subfield><subfield code="b">Nova Science Publishers,</subfield><subfield code="c">[2011]</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="347" ind1=" " ind2=" "><subfield code="a">data file</subfield><subfield code="2">rda</subfield></datafield><datafield tag="490" ind1="1" ind2=" "><subfield code="a">Nanotechnology science and technology</subfield></datafield><datafield tag="504" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references and index.</subfield></datafield><datafield tag="588" ind1=" " ind2=" "><subfield code="a">Description based on print version record.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English.</subfield></datafield><datafield tag="505" ind1="0" ind2=" "><subfield code="a">Intro -- SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES: SYNTHESIS, SURFACE ENGINEERING, CYTOTOXICITY AND BIOMEDICAL APPLICATIONS -- SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES: SYNTHESIS, SURFACE ENGINEERING, CYTOTOXICITY AND BIOMEDICAL APPLICATIONS -- LIBRARY OF CONGRESS CATALOGING-IN-PUBLICATION DATA -- DEDICATION -- ABOUT THE AUTHORS -- CONTENTS -- PREFACE -- Chapter 1 INTRODUCTORY TO THE BOOK -- 1.1. SEMICONDUCTING NANOPARTICLES -- 1.2. IRON OXIDE NANOPARTICLES -- 1.3. BIOMINERALIZATION -- 1.4. TYPES OF MAGNETIC IRON OXIDES -- 1.5. SYNTHESIS OF SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES (SPIONS): CHEMICAL COPRECIPITATION -- 1.6. DESIGN OF EXPERIMENTS (DOE) FOR SYNTHESIS OF SPIONS -- REFERENCES -- Chapter 2 SYNTHESIS OF SPIONS -- 2.1. NUCLEATION OF NANOPARTICLES -- 2.2. SYNTHESIS METHODS -- 2.2.1. Chemical Methods -- 2.2.1.1. Co-precipitation -- 2.2.1.2. Microemulsions -- 2.2.1.3. Hydrothermal -- 2.2.1.4. Thermal Decomposition -- 2.2.1.5. Sol-gel -- 2.2.1.6. Polyol -- 2.2.1.7. Sonochemical -- 2.2.1.8. Electrochemical Deposition -- 2.2.2. Physical Methods -- 2.2.2.1. Flow Injection -- 2.2.2.2. Aerosol/Vapor -- 2.2.2.3. Pulsed Laser Ablation -- 2.2.2.4. Laser Induced Pyrolysis -- 2.2.2.5. Powder Ball Milling -- 2.2.3. Biological/ Bio-mineralization -- REFERENCES -- Chapter 3 APPLICATION OF STATISTICAL TECHNIQUES -- 3.1. THE TWO SAMPLE T-TEST -- 3.2. HYPOTHESIS TESTING FOR OUTLIER DETECTION -- GRUBBS' TEST -- 3.3. DESIGN OF EXPERIMENTS -- Remark: How to Perform the Analysis with More than Two Factors, Two Levels? -- 3.3.1. Checking Model Assumptions: Effect of Potentially Outlying Observations -- REFERENCES -- Chapter 4 COATINGS OF SPIONS -- 4.1. COLLOIDAL STABILITY OF SPIONS -- 4.2. POLYMERIC COATING -- 4.2.1. Polyethylene Glycol -- 4.2.2. Polyethylene Glycol Fumarate -- 4.2.3. Polyvinyl Alcohol -- 4.2.4. Polyacrylic Acid.</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">4.2.5. Poly(N-isopropylacrylamide) -- 4.2.6. Dextran -- 4.2.7. Poly(D, L-lactide) -- 4.2.8. Poly(D, L-lactide-co-glycolide) -- 4.2.9. Alginate -- 4.2.10. Chitosan and Polyethylenimine -- 4.3. NON-POLYMERIC COATING -- 4.3.1. Gold -- 4.3.2. Silica -- 4.4. FUNCTIONALIZATION OF SPIONS -- REFERENCES -- Chapter 5 CYTOTOXICITY OF SPIONS -- 5.1. BIOCOMPATIBILITY VERSUS TOXICITY -- 5.1.1. Biocompatibility -- 5.1.2. Cytotoxicity -- 5.2. IN VITRO TOXICITY ASSAYS -- 5.2.1. Metabolic Activity -- 5.2.1.1. MTT Assay -- 5.2.1.1.1. Modification of MTT Method -- 5.2.1.2. MTS and XTT Assays -- 5.2.1.2.1. MTS Assay -- 5.2.1.2.2. XTT Assay -- 5.2.1.3. Redox Assay -- 5.2.1.4. Adenosine Triphosphate Assay -- 5.12.1.5. Cytochrome C Assay -- 5.2.1.6. Nitroblue Tetrazolium (NBT) Assay -- 5.2.1.7. WST Assay -- 5.2.2. Membrane Integrity -- 5.2.2.1. LDH Assay -- 5.2.2.2. The Calcein AM, Live/Dead and Ethidium Homodimer Assay -- 5.2.2.3. Dye Assays -- 5.2.2.3.1. Erythrosine B (EB) Assay -- 5.2.2.3.2. Propidium Iodide (PI) Assay -- 5.2.2.3.3. Neutral Red (NR) Assay -- 5.2.2.3.4. Bromodeoxyuridine (BrdU) Assay -- 5.2.2.3.5. Trypan Blue (TB) Assay -- 5.2.2.3.6. DNA Hoechst Assay -- 5.2.2.3.7. Other Dye Assays -- 5.2.3. Cell Proliferation Assay -- 5.2.3.1. Cell Cycle Assay -- 5.2.3.2. [3H] Thymidine Incorporation Assay -- 5.2.4. Apoptosis Detection -- 5.2.4.1. Flow Cytometry -- 5.2.4.2. Comet Assay -- 5.3. IN VIVO TOXICITY -- 5.4. PHARMACOKINETICS AND BIODISTRIBUTION -- REFERENCES -- Chapter 6 APPLICATION OF SPIONS* -- 6.1. SPIONS AS MAGNETIC RESONANCE IMAGING CONTRAST AGENT -- Introduction -- Paramagnetic Agents -- Superparamagnetic Agents -- Current Clinical Use of (U)SPIONs as Contrast Agents -- Oral Contrast Agents -- Injectable Contrast Agents -- Ferumoxides (Feridex I.V./Endorem) -- Ferucarbotran/SHU555A (Resovist/Cliavist) -- Ferumoxtran-10 (USPIO) (Combidex/Senerem).</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">PEG-feron (Feruglose/Clariscan) -- Ferucarbotran (USPIO)/SHU555C (Supravist) -- Ferumoxytol (USPIO) (Feraheme) -- 6.2. SPIONS FOR MAGNETIC LABELING OF CELLS -- Introduction -- SPIONs and its Modification for Labeling -- Transfection Agents Mediated Modification of SPIONs for Cell Labeling -- Optimization of Cell Labeling with Simple Incubation -- Assay to Determine the Toxicity of Labeling -- 6.3. SPIONS AND MAGNETICALLY LABELED CELLS FOR MULTIMODAL REGIMENS -- SPIONs for Multimodal Imaging -- Cells for Multimodal Imaging -- 6.4. SPIONS AS DRUG DELIVERY VEHICLES -- Introduction -- Active Targeting Using Ligand Substrate Mechanisms, Antigen-Antibody or Receptors -- Enhanced Permeability Retention (EPR) Effect -- Convection-Enhanced Delivery -- Magnet Activated Delivery -- Drug Delivery by Direct Injection -- 6.5. SPIONS FOR HYPERTHERMIA TREATMENT -- 6.6. SPIONS FOR ENHANCED TRANSFECTION OF DNA (MAGNETOFECTION) -- 6.7. SPIONS FOR CELL/PROTEIN SEPARATION -- 6.8. SPIONS AS CATALYST -- 6.9. 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| id | ZDB-4-EBA-on1162020434 |
| illustrated | Illustrated |
| indexdate | 2024-11-27T13:29:56Z |
| institution | BVB |
| isbn | 9781617286315 1617286311 |
| language | English |
| lccn | 2020678588 |
| oclc_num | 1162020434 |
| open_access_boolean | |
| owner | MAIN DE-863 DE-BY-FWS |
| owner_facet | MAIN DE-863 DE-BY-FWS |
| physical | 1 online resource. |
| psigel | ZDB-4-EBA |
| publishDate | 2011 |
| publishDateSearch | 2011 |
| publishDateSort | 2011 |
| publisher | Nova Science Publishers, |
| record_format | marc |
| series | Nanotechnology science and technology series. |
| series2 | Nanotechnology science and technology |
| spelling | Superparamagnetic iron oxide nanoparticles : synthesis, surface engineering, cytotoxicity, and biomedical applications / Morteza Mahmoudi ... [and others]. New York : Nova Science Publishers, [2011] 1 online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier data file rda Nanotechnology science and technology Includes bibliographical references and index. Description based on print version record. English. Intro -- SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES: SYNTHESIS, SURFACE ENGINEERING, CYTOTOXICITY AND BIOMEDICAL APPLICATIONS -- SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES: SYNTHESIS, SURFACE ENGINEERING, CYTOTOXICITY AND BIOMEDICAL APPLICATIONS -- LIBRARY OF CONGRESS CATALOGING-IN-PUBLICATION DATA -- DEDICATION -- ABOUT THE AUTHORS -- CONTENTS -- PREFACE -- Chapter 1 INTRODUCTORY TO THE BOOK -- 1.1. SEMICONDUCTING NANOPARTICLES -- 1.2. IRON OXIDE NANOPARTICLES -- 1.3. BIOMINERALIZATION -- 1.4. TYPES OF MAGNETIC IRON OXIDES -- 1.5. SYNTHESIS OF SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES (SPIONS): CHEMICAL COPRECIPITATION -- 1.6. DESIGN OF EXPERIMENTS (DOE) FOR SYNTHESIS OF SPIONS -- REFERENCES -- Chapter 2 SYNTHESIS OF SPIONS -- 2.1. NUCLEATION OF NANOPARTICLES -- 2.2. SYNTHESIS METHODS -- 2.2.1. Chemical Methods -- 2.2.1.1. Co-precipitation -- 2.2.1.2. Microemulsions -- 2.2.1.3. Hydrothermal -- 2.2.1.4. Thermal Decomposition -- 2.2.1.5. Sol-gel -- 2.2.1.6. Polyol -- 2.2.1.7. Sonochemical -- 2.2.1.8. Electrochemical Deposition -- 2.2.2. Physical Methods -- 2.2.2.1. Flow Injection -- 2.2.2.2. Aerosol/Vapor -- 2.2.2.3. Pulsed Laser Ablation -- 2.2.2.4. Laser Induced Pyrolysis -- 2.2.2.5. Powder Ball Milling -- 2.2.3. Biological/ Bio-mineralization -- REFERENCES -- Chapter 3 APPLICATION OF STATISTICAL TECHNIQUES -- 3.1. THE TWO SAMPLE T-TEST -- 3.2. HYPOTHESIS TESTING FOR OUTLIER DETECTION -- GRUBBS' TEST -- 3.3. DESIGN OF EXPERIMENTS -- Remark: How to Perform the Analysis with More than Two Factors, Two Levels? -- 3.3.1. Checking Model Assumptions: Effect of Potentially Outlying Observations -- REFERENCES -- Chapter 4 COATINGS OF SPIONS -- 4.1. COLLOIDAL STABILITY OF SPIONS -- 4.2. POLYMERIC COATING -- 4.2.1. Polyethylene Glycol -- 4.2.2. Polyethylene Glycol Fumarate -- 4.2.3. Polyvinyl Alcohol -- 4.2.4. Polyacrylic Acid. 4.2.5. Poly(N-isopropylacrylamide) -- 4.2.6. Dextran -- 4.2.7. Poly(D, L-lactide) -- 4.2.8. Poly(D, L-lactide-co-glycolide) -- 4.2.9. Alginate -- 4.2.10. Chitosan and Polyethylenimine -- 4.3. NON-POLYMERIC COATING -- 4.3.1. Gold -- 4.3.2. Silica -- 4.4. FUNCTIONALIZATION OF SPIONS -- REFERENCES -- Chapter 5 CYTOTOXICITY OF SPIONS -- 5.1. BIOCOMPATIBILITY VERSUS TOXICITY -- 5.1.1. Biocompatibility -- 5.1.2. Cytotoxicity -- 5.2. IN VITRO TOXICITY ASSAYS -- 5.2.1. Metabolic Activity -- 5.2.1.1. MTT Assay -- 5.2.1.1.1. Modification of MTT Method -- 5.2.1.2. MTS and XTT Assays -- 5.2.1.2.1. MTS Assay -- 5.2.1.2.2. XTT Assay -- 5.2.1.3. Redox Assay -- 5.2.1.4. Adenosine Triphosphate Assay -- 5.12.1.5. Cytochrome C Assay -- 5.2.1.6. Nitroblue Tetrazolium (NBT) Assay -- 5.2.1.7. WST Assay -- 5.2.2. Membrane Integrity -- 5.2.2.1. LDH Assay -- 5.2.2.2. The Calcein AM, Live/Dead and Ethidium Homodimer Assay -- 5.2.2.3. Dye Assays -- 5.2.2.3.1. Erythrosine B (EB) Assay -- 5.2.2.3.2. Propidium Iodide (PI) Assay -- 5.2.2.3.3. Neutral Red (NR) Assay -- 5.2.2.3.4. Bromodeoxyuridine (BrdU) Assay -- 5.2.2.3.5. Trypan Blue (TB) Assay -- 5.2.2.3.6. DNA Hoechst Assay -- 5.2.2.3.7. Other Dye Assays -- 5.2.3. Cell Proliferation Assay -- 5.2.3.1. Cell Cycle Assay -- 5.2.3.2. [3H] Thymidine Incorporation Assay -- 5.2.4. Apoptosis Detection -- 5.2.4.1. Flow Cytometry -- 5.2.4.2. Comet Assay -- 5.3. IN VIVO TOXICITY -- 5.4. PHARMACOKINETICS AND BIODISTRIBUTION -- REFERENCES -- Chapter 6 APPLICATION OF SPIONS* -- 6.1. SPIONS AS MAGNETIC RESONANCE IMAGING CONTRAST AGENT -- Introduction -- Paramagnetic Agents -- Superparamagnetic Agents -- Current Clinical Use of (U)SPIONs as Contrast Agents -- Oral Contrast Agents -- Injectable Contrast Agents -- Ferumoxides (Feridex I.V./Endorem) -- Ferucarbotran/SHU555A (Resovist/Cliavist) -- Ferumoxtran-10 (USPIO) (Combidex/Senerem). PEG-feron (Feruglose/Clariscan) -- Ferucarbotran (USPIO)/SHU555C (Supravist) -- Ferumoxytol (USPIO) (Feraheme) -- 6.2. SPIONS FOR MAGNETIC LABELING OF CELLS -- Introduction -- SPIONs and its Modification for Labeling -- Transfection Agents Mediated Modification of SPIONs for Cell Labeling -- Optimization of Cell Labeling with Simple Incubation -- Assay to Determine the Toxicity of Labeling -- 6.3. SPIONS AND MAGNETICALLY LABELED CELLS FOR MULTIMODAL REGIMENS -- SPIONs for Multimodal Imaging -- Cells for Multimodal Imaging -- 6.4. SPIONS AS DRUG DELIVERY VEHICLES -- Introduction -- Active Targeting Using Ligand Substrate Mechanisms, Antigen-Antibody or Receptors -- Enhanced Permeability Retention (EPR) Effect -- Convection-Enhanced Delivery -- Magnet Activated Delivery -- Drug Delivery by Direct Injection -- 6.5. SPIONS FOR HYPERTHERMIA TREATMENT -- 6.6. SPIONS FOR ENHANCED TRANSFECTION OF DNA (MAGNETOFECTION) -- 6.7. SPIONS FOR CELL/PROTEIN SEPARATION -- 6.8. SPIONS AS CATALYST -- 6.9. SPIONS FOR TISSUE REPAIR -- REFERENCES -- INDEX. Nanomedicine. http://id.loc.gov/authorities/subjects/sh2007008651 Ferric oxide Magnetic properties. Nanoparticles. http://id.loc.gov/authorities/subjects/sh85089689 Nanoparticles https://id.nlm.nih.gov/mesh/D053758 Nanomedicine https://id.nlm.nih.gov/mesh/D050997 Nanoparticules. Nanomédecine. MEDICAL Instruments & Supplies. bisacsh Nanomedicine fast Nanoparticles fast Mahmoudi, Morteza, 1979- https://id.oclc.org/worldcat/entity/E39PBJjhC7CvHKJGbCfhBvBByd http://id.loc.gov/authorities/names/n2010062346 has work: Superparamagnetic iron oxide nanoparticles (Text) https://id.oclc.org/worldcat/entity/E39PCFRKpPwpfvp63jd64CdwBX https://id.oclc.org/worldcat/ontology/hasWork Print version: Superparamagnetic iron oxide nanoparticles New York : Nova Science Publishers, c2011. 9781616689643 (hardcover) (DLC) 2010036438 Nanotechnology science and technology series. http://id.loc.gov/authorities/names/no2009109464 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=443078 Volltext |
| spellingShingle | Superparamagnetic iron oxide nanoparticles : synthesis, surface engineering, cytotoxicity, and biomedical applications / Nanotechnology science and technology series. Intro -- SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES: SYNTHESIS, SURFACE ENGINEERING, CYTOTOXICITY AND BIOMEDICAL APPLICATIONS -- SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES: SYNTHESIS, SURFACE ENGINEERING, CYTOTOXICITY AND BIOMEDICAL APPLICATIONS -- LIBRARY OF CONGRESS CATALOGING-IN-PUBLICATION DATA -- DEDICATION -- ABOUT THE AUTHORS -- CONTENTS -- PREFACE -- Chapter 1 INTRODUCTORY TO THE BOOK -- 1.1. SEMICONDUCTING NANOPARTICLES -- 1.2. IRON OXIDE NANOPARTICLES -- 1.3. BIOMINERALIZATION -- 1.4. TYPES OF MAGNETIC IRON OXIDES -- 1.5. SYNTHESIS OF SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES (SPIONS): CHEMICAL COPRECIPITATION -- 1.6. DESIGN OF EXPERIMENTS (DOE) FOR SYNTHESIS OF SPIONS -- REFERENCES -- Chapter 2 SYNTHESIS OF SPIONS -- 2.1. NUCLEATION OF NANOPARTICLES -- 2.2. SYNTHESIS METHODS -- 2.2.1. Chemical Methods -- 2.2.1.1. Co-precipitation -- 2.2.1.2. Microemulsions -- 2.2.1.3. Hydrothermal -- 2.2.1.4. Thermal Decomposition -- 2.2.1.5. Sol-gel -- 2.2.1.6. Polyol -- 2.2.1.7. Sonochemical -- 2.2.1.8. Electrochemical Deposition -- 2.2.2. Physical Methods -- 2.2.2.1. Flow Injection -- 2.2.2.2. Aerosol/Vapor -- 2.2.2.3. Pulsed Laser Ablation -- 2.2.2.4. Laser Induced Pyrolysis -- 2.2.2.5. Powder Ball Milling -- 2.2.3. Biological/ Bio-mineralization -- REFERENCES -- Chapter 3 APPLICATION OF STATISTICAL TECHNIQUES -- 3.1. THE TWO SAMPLE T-TEST -- 3.2. HYPOTHESIS TESTING FOR OUTLIER DETECTION -- GRUBBS' TEST -- 3.3. DESIGN OF EXPERIMENTS -- Remark: How to Perform the Analysis with More than Two Factors, Two Levels? -- 3.3.1. Checking Model Assumptions: Effect of Potentially Outlying Observations -- REFERENCES -- Chapter 4 COATINGS OF SPIONS -- 4.1. COLLOIDAL STABILITY OF SPIONS -- 4.2. POLYMERIC COATING -- 4.2.1. Polyethylene Glycol -- 4.2.2. Polyethylene Glycol Fumarate -- 4.2.3. Polyvinyl Alcohol -- 4.2.4. Polyacrylic Acid. 4.2.5. Poly(N-isopropylacrylamide) -- 4.2.6. Dextran -- 4.2.7. Poly(D, L-lactide) -- 4.2.8. Poly(D, L-lactide-co-glycolide) -- 4.2.9. Alginate -- 4.2.10. Chitosan and Polyethylenimine -- 4.3. NON-POLYMERIC COATING -- 4.3.1. Gold -- 4.3.2. Silica -- 4.4. FUNCTIONALIZATION OF SPIONS -- REFERENCES -- Chapter 5 CYTOTOXICITY OF SPIONS -- 5.1. BIOCOMPATIBILITY VERSUS TOXICITY -- 5.1.1. Biocompatibility -- 5.1.2. Cytotoxicity -- 5.2. IN VITRO TOXICITY ASSAYS -- 5.2.1. Metabolic Activity -- 5.2.1.1. MTT Assay -- 5.2.1.1.1. Modification of MTT Method -- 5.2.1.2. MTS and XTT Assays -- 5.2.1.2.1. MTS Assay -- 5.2.1.2.2. XTT Assay -- 5.2.1.3. Redox Assay -- 5.2.1.4. Adenosine Triphosphate Assay -- 5.12.1.5. Cytochrome C Assay -- 5.2.1.6. Nitroblue Tetrazolium (NBT) Assay -- 5.2.1.7. WST Assay -- 5.2.2. Membrane Integrity -- 5.2.2.1. LDH Assay -- 5.2.2.2. The Calcein AM, Live/Dead and Ethidium Homodimer Assay -- 5.2.2.3. Dye Assays -- 5.2.2.3.1. Erythrosine B (EB) Assay -- 5.2.2.3.2. Propidium Iodide (PI) Assay -- 5.2.2.3.3. Neutral Red (NR) Assay -- 5.2.2.3.4. Bromodeoxyuridine (BrdU) Assay -- 5.2.2.3.5. Trypan Blue (TB) Assay -- 5.2.2.3.6. DNA Hoechst Assay -- 5.2.2.3.7. Other Dye Assays -- 5.2.3. Cell Proliferation Assay -- 5.2.3.1. Cell Cycle Assay -- 5.2.3.2. [3H] Thymidine Incorporation Assay -- 5.2.4. Apoptosis Detection -- 5.2.4.1. Flow Cytometry -- 5.2.4.2. Comet Assay -- 5.3. IN VIVO TOXICITY -- 5.4. PHARMACOKINETICS AND BIODISTRIBUTION -- REFERENCES -- Chapter 6 APPLICATION OF SPIONS* -- 6.1. SPIONS AS MAGNETIC RESONANCE IMAGING CONTRAST AGENT -- Introduction -- Paramagnetic Agents -- Superparamagnetic Agents -- Current Clinical Use of (U)SPIONs as Contrast Agents -- Oral Contrast Agents -- Injectable Contrast Agents -- Ferumoxides (Feridex I.V./Endorem) -- Ferucarbotran/SHU555A (Resovist/Cliavist) -- Ferumoxtran-10 (USPIO) (Combidex/Senerem). PEG-feron (Feruglose/Clariscan) -- Ferucarbotran (USPIO)/SHU555C (Supravist) -- Ferumoxytol (USPIO) (Feraheme) -- 6.2. SPIONS FOR MAGNETIC LABELING OF CELLS -- Introduction -- SPIONs and its Modification for Labeling -- Transfection Agents Mediated Modification of SPIONs for Cell Labeling -- Optimization of Cell Labeling with Simple Incubation -- Assay to Determine the Toxicity of Labeling -- 6.3. SPIONS AND MAGNETICALLY LABELED CELLS FOR MULTIMODAL REGIMENS -- SPIONs for Multimodal Imaging -- Cells for Multimodal Imaging -- 6.4. SPIONS AS DRUG DELIVERY VEHICLES -- Introduction -- Active Targeting Using Ligand Substrate Mechanisms, Antigen-Antibody or Receptors -- Enhanced Permeability Retention (EPR) Effect -- Convection-Enhanced Delivery -- Magnet Activated Delivery -- Drug Delivery by Direct Injection -- 6.5. SPIONS FOR HYPERTHERMIA TREATMENT -- 6.6. SPIONS FOR ENHANCED TRANSFECTION OF DNA (MAGNETOFECTION) -- 6.7. SPIONS FOR CELL/PROTEIN SEPARATION -- 6.8. SPIONS AS CATALYST -- 6.9. SPIONS FOR TISSUE REPAIR -- REFERENCES -- INDEX. Nanomedicine. http://id.loc.gov/authorities/subjects/sh2007008651 Ferric oxide Magnetic properties. Nanoparticles. http://id.loc.gov/authorities/subjects/sh85089689 Nanoparticles https://id.nlm.nih.gov/mesh/D053758 Nanomedicine https://id.nlm.nih.gov/mesh/D050997 Nanoparticules. Nanomédecine. MEDICAL Instruments & Supplies. bisacsh Nanomedicine fast Nanoparticles fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh2007008651 http://id.loc.gov/authorities/subjects/sh85089689 https://id.nlm.nih.gov/mesh/D053758 https://id.nlm.nih.gov/mesh/D050997 |
| title | Superparamagnetic iron oxide nanoparticles : synthesis, surface engineering, cytotoxicity, and biomedical applications / |
| title_auth | Superparamagnetic iron oxide nanoparticles : synthesis, surface engineering, cytotoxicity, and biomedical applications / |
| title_exact_search | Superparamagnetic iron oxide nanoparticles : synthesis, surface engineering, cytotoxicity, and biomedical applications / |
| title_full | Superparamagnetic iron oxide nanoparticles : synthesis, surface engineering, cytotoxicity, and biomedical applications / Morteza Mahmoudi ... [and others]. |
| title_fullStr | Superparamagnetic iron oxide nanoparticles : synthesis, surface engineering, cytotoxicity, and biomedical applications / Morteza Mahmoudi ... [and others]. |
| title_full_unstemmed | Superparamagnetic iron oxide nanoparticles : synthesis, surface engineering, cytotoxicity, and biomedical applications / Morteza Mahmoudi ... [and others]. |
| title_short | Superparamagnetic iron oxide nanoparticles : |
| title_sort | superparamagnetic iron oxide nanoparticles synthesis surface engineering cytotoxicity and biomedical applications |
| title_sub | synthesis, surface engineering, cytotoxicity, and biomedical applications / |
| topic | Nanomedicine. http://id.loc.gov/authorities/subjects/sh2007008651 Ferric oxide Magnetic properties. Nanoparticles. http://id.loc.gov/authorities/subjects/sh85089689 Nanoparticles https://id.nlm.nih.gov/mesh/D053758 Nanomedicine https://id.nlm.nih.gov/mesh/D050997 Nanoparticules. Nanomédecine. MEDICAL Instruments & Supplies. bisacsh Nanomedicine fast Nanoparticles fast |
| topic_facet | Nanomedicine. Ferric oxide Magnetic properties. Nanoparticles. Nanoparticles Nanomedicine Nanoparticules. Nanomédecine. MEDICAL Instruments & Supplies. |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=443078 |
| work_keys_str_mv | AT mahmoudimorteza superparamagneticironoxidenanoparticlessynthesissurfaceengineeringcytotoxicityandbiomedicalapplications |