Triple-Negative Breast Cancer.:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Hauppauge :
Nova Science Publishers, Inc.,
2017.
|
| Schriftenreihe: | Cancer etiology, diagnosis, and treatments.
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | 1 online resource (132 pages) |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9781536123906 1536123900 |
Internformat
MARC
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| 300 | |a 1 online resource (132 pages) | ||
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| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Preface; Chapter 1; The Role of Exosomes in Breast Cancer: What Have We Learned in Ten Years?; Abstract; Introduction; Exosomes: An Overview; Exosomes: In Cancer; Cancer-Associated Exosomes Containing Proteins; Cancer-Associated Exosomes Containing Nucleic Acids; miRNA-containing Exosomes; mRNA-Containing Exosomes; DNA-containing Exosomes; Cancer-Associated Exosomes Containing Lipids; Exosomes in the Breast Tumor Microenvironment; Exosomes in Hypoxia, Epithelial -- Mesenchymal Transition, ROS Production and Autophagy; Exosomes in Metastasis; Exosomes and Drug Resistance. | |
| 505 | 8 | |a Conclusion and Future PerspectivesReferences; Chapter 2; Correlations between BRCA Gene Mutations and the High Risk of TNBC as Defined by the Defect of Estrogen Signaling; Abstract; Introduction; Interplay Between Endogenous Estrogens and Wild-Type BRCA Genes; Correlations between BRCA Gene Mutations and Defective Estrogen Signaling; Decreased ER-Alpha Expression in BRCA Gene Mutation Carrier Cells; Decreased Estradiol-Liganded Transcriptional Activity of ERs in BRCA Gene Deficient Cells; Defensive Counteractions Against BRCA Gene Defects. | |
| 505 | 8 | |a Increased Aromatase Activity Associated with BRCA Gene MutationHyperestrogenism as a Compensatory Mechanism in Women with BRCA Gene Mutation; Increased Ligand-Independent Transcriptional Activity in Cells with BRCA1 Mutation; Hormonal Risk Factors for Overall Breast Cancer and TNBC; Correlations between Menopausal Status and TNBC Risk; Correlations between Reproductive History and the Risk of Different Breast Cancer Subtypes; Conclusion; References; Chapter 3; The Role of Tumor Infiltrating Lymphocytes (TILs) in Triple Negative Breast Cancer (TNBC); Abstract; Introduction. | |
| 505 | 8 | |a Pathologic and Molecular Heterogeneity of TNBCTumor-Infiltrating Lymphocytes in TNBC; a. TILs as a Prognostic Factor; b. TILs as a Predictive Factor; c. TILs as Biomarkers of Residual Disease; Targeting the Immune System in Triple-Negative Breast Cancer: Potential Role of the PD-1/PD-L1 Pathway as a Biomarker; Conclusion; References; Index; Blank Page. | |
| 504 | |a Includes bibliographical references and index. | ||
| 650 | 0 | |a Breast |x Cancer. |0 http://id.loc.gov/authorities/subjects/sh85016679 | |
| 650 | 2 | |a Breast Neoplasms |0 https://id.nlm.nih.gov/mesh/D001943 | |
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| 650 | 7 | |a Breast |x Cancer |2 fast | |
| 776 | 0 | 8 | |i Print version: |a Montgomery, Marion. |t Triple-Negative Breast Cancer: Biomarkers, Emerging Therapeutic Strategies and Clinical Challenges. |d Hauppauge : Nova Science Publishers, Inc., ©2017 |z 9781536123722 |
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| contents | Preface; Chapter 1; The Role of Exosomes in Breast Cancer: What Have We Learned in Ten Years?; Abstract; Introduction; Exosomes: An Overview; Exosomes: In Cancer; Cancer-Associated Exosomes Containing Proteins; Cancer-Associated Exosomes Containing Nucleic Acids; miRNA-containing Exosomes; mRNA-Containing Exosomes; DNA-containing Exosomes; Cancer-Associated Exosomes Containing Lipids; Exosomes in the Breast Tumor Microenvironment; Exosomes in Hypoxia, Epithelial -- Mesenchymal Transition, ROS Production and Autophagy; Exosomes in Metastasis; Exosomes and Drug Resistance. Conclusion and Future PerspectivesReferences; Chapter 2; Correlations between BRCA Gene Mutations and the High Risk of TNBC as Defined by the Defect of Estrogen Signaling; Abstract; Introduction; Interplay Between Endogenous Estrogens and Wild-Type BRCA Genes; Correlations between BRCA Gene Mutations and Defective Estrogen Signaling; Decreased ER-Alpha Expression in BRCA Gene Mutation Carrier Cells; Decreased Estradiol-Liganded Transcriptional Activity of ERs in BRCA Gene Deficient Cells; Defensive Counteractions Against BRCA Gene Defects. Increased Aromatase Activity Associated with BRCA Gene MutationHyperestrogenism as a Compensatory Mechanism in Women with BRCA Gene Mutation; Increased Ligand-Independent Transcriptional Activity in Cells with BRCA1 Mutation; Hormonal Risk Factors for Overall Breast Cancer and TNBC; Correlations between Menopausal Status and TNBC Risk; Correlations between Reproductive History and the Risk of Different Breast Cancer Subtypes; Conclusion; References; Chapter 3; The Role of Tumor Infiltrating Lymphocytes (TILs) in Triple Negative Breast Cancer (TNBC); Abstract; Introduction. Pathologic and Molecular Heterogeneity of TNBCTumor-Infiltrating Lymphocytes in TNBC; a. TILs as a Prognostic Factor; b. TILs as a Predictive Factor; c. TILs as Biomarkers of Residual Disease; Targeting the Immune System in Triple-Negative Breast Cancer: Potential Role of the PD-1/PD-L1 Pathway as a Biomarker; Conclusion; References; Index; Blank Page. |
| ctrlnum | (OCoLC)1003261866 |
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| discipline | Medizin |
| format | Electronic eBook |
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| id | ZDB-4-EBA-on1003261866 |
| illustrated | Not Illustrated |
| indexdate | 2024-11-27T13:28:00Z |
| institution | BVB |
| isbn | 9781536123906 1536123900 |
| language | English |
| oclc_num | 1003261866 |
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| owner_facet | MAIN DE-863 DE-BY-FWS |
| physical | 1 online resource (132 pages) |
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| publishDate | 2017 |
| publishDateSearch | 2017 |
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| series | Cancer etiology, diagnosis, and treatments. |
| series2 | Cancer Etiology, Diagnosis and Treatments |
| spelling | Montgomery, Marion. Triple-Negative Breast Cancer. Hauppauge : Nova Science Publishers, Inc., 2017. 1 online resource (132 pages) text txt rdacontent computer c rdamedia online resource cr rdacarrier Cancer Etiology, Diagnosis and Treatments Print version record. Preface; Chapter 1; The Role of Exosomes in Breast Cancer: What Have We Learned in Ten Years?; Abstract; Introduction; Exosomes: An Overview; Exosomes: In Cancer; Cancer-Associated Exosomes Containing Proteins; Cancer-Associated Exosomes Containing Nucleic Acids; miRNA-containing Exosomes; mRNA-Containing Exosomes; DNA-containing Exosomes; Cancer-Associated Exosomes Containing Lipids; Exosomes in the Breast Tumor Microenvironment; Exosomes in Hypoxia, Epithelial -- Mesenchymal Transition, ROS Production and Autophagy; Exosomes in Metastasis; Exosomes and Drug Resistance. Conclusion and Future PerspectivesReferences; Chapter 2; Correlations between BRCA Gene Mutations and the High Risk of TNBC as Defined by the Defect of Estrogen Signaling; Abstract; Introduction; Interplay Between Endogenous Estrogens and Wild-Type BRCA Genes; Correlations between BRCA Gene Mutations and Defective Estrogen Signaling; Decreased ER-Alpha Expression in BRCA Gene Mutation Carrier Cells; Decreased Estradiol-Liganded Transcriptional Activity of ERs in BRCA Gene Deficient Cells; Defensive Counteractions Against BRCA Gene Defects. Increased Aromatase Activity Associated with BRCA Gene MutationHyperestrogenism as a Compensatory Mechanism in Women with BRCA Gene Mutation; Increased Ligand-Independent Transcriptional Activity in Cells with BRCA1 Mutation; Hormonal Risk Factors for Overall Breast Cancer and TNBC; Correlations between Menopausal Status and TNBC Risk; Correlations between Reproductive History and the Risk of Different Breast Cancer Subtypes; Conclusion; References; Chapter 3; The Role of Tumor Infiltrating Lymphocytes (TILs) in Triple Negative Breast Cancer (TNBC); Abstract; Introduction. Pathologic and Molecular Heterogeneity of TNBCTumor-Infiltrating Lymphocytes in TNBC; a. TILs as a Prognostic Factor; b. TILs as a Predictive Factor; c. TILs as Biomarkers of Residual Disease; Targeting the Immune System in Triple-Negative Breast Cancer: Potential Role of the PD-1/PD-L1 Pathway as a Biomarker; Conclusion; References; Index; Blank Page. Includes bibliographical references and index. Breast Cancer. http://id.loc.gov/authorities/subjects/sh85016679 Breast Neoplasms https://id.nlm.nih.gov/mesh/D001943 Sein Cancer. HEALTH & FITNESS Diseases General. bisacsh MEDICAL Clinical Medicine. bisacsh MEDICAL Diseases. bisacsh MEDICAL Evidence-Based Medicine. bisacsh MEDICAL Internal Medicine. bisacsh Breast Cancer fast Print version: Montgomery, Marion. Triple-Negative Breast Cancer: Biomarkers, Emerging Therapeutic Strategies and Clinical Challenges. Hauppauge : Nova Science Publishers, Inc., ©2017 9781536123722 Cancer etiology, diagnosis, and treatments. http://id.loc.gov/authorities/names/n2009183163 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1562819 Volltext |
| spellingShingle | Montgomery, Marion Triple-Negative Breast Cancer. Cancer etiology, diagnosis, and treatments. Preface; Chapter 1; The Role of Exosomes in Breast Cancer: What Have We Learned in Ten Years?; Abstract; Introduction; Exosomes: An Overview; Exosomes: In Cancer; Cancer-Associated Exosomes Containing Proteins; Cancer-Associated Exosomes Containing Nucleic Acids; miRNA-containing Exosomes; mRNA-Containing Exosomes; DNA-containing Exosomes; Cancer-Associated Exosomes Containing Lipids; Exosomes in the Breast Tumor Microenvironment; Exosomes in Hypoxia, Epithelial -- Mesenchymal Transition, ROS Production and Autophagy; Exosomes in Metastasis; Exosomes and Drug Resistance. Conclusion and Future PerspectivesReferences; Chapter 2; Correlations between BRCA Gene Mutations and the High Risk of TNBC as Defined by the Defect of Estrogen Signaling; Abstract; Introduction; Interplay Between Endogenous Estrogens and Wild-Type BRCA Genes; Correlations between BRCA Gene Mutations and Defective Estrogen Signaling; Decreased ER-Alpha Expression in BRCA Gene Mutation Carrier Cells; Decreased Estradiol-Liganded Transcriptional Activity of ERs in BRCA Gene Deficient Cells; Defensive Counteractions Against BRCA Gene Defects. Increased Aromatase Activity Associated with BRCA Gene MutationHyperestrogenism as a Compensatory Mechanism in Women with BRCA Gene Mutation; Increased Ligand-Independent Transcriptional Activity in Cells with BRCA1 Mutation; Hormonal Risk Factors for Overall Breast Cancer and TNBC; Correlations between Menopausal Status and TNBC Risk; Correlations between Reproductive History and the Risk of Different Breast Cancer Subtypes; Conclusion; References; Chapter 3; The Role of Tumor Infiltrating Lymphocytes (TILs) in Triple Negative Breast Cancer (TNBC); Abstract; Introduction. Pathologic and Molecular Heterogeneity of TNBCTumor-Infiltrating Lymphocytes in TNBC; a. TILs as a Prognostic Factor; b. TILs as a Predictive Factor; c. TILs as Biomarkers of Residual Disease; Targeting the Immune System in Triple-Negative Breast Cancer: Potential Role of the PD-1/PD-L1 Pathway as a Biomarker; Conclusion; References; Index; Blank Page. Breast Cancer. http://id.loc.gov/authorities/subjects/sh85016679 Breast Neoplasms https://id.nlm.nih.gov/mesh/D001943 Sein Cancer. HEALTH & FITNESS Diseases General. bisacsh MEDICAL Clinical Medicine. bisacsh MEDICAL Diseases. bisacsh MEDICAL Evidence-Based Medicine. bisacsh MEDICAL Internal Medicine. bisacsh Breast Cancer fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85016679 https://id.nlm.nih.gov/mesh/D001943 |
| title | Triple-Negative Breast Cancer. |
| title_auth | Triple-Negative Breast Cancer. |
| title_exact_search | Triple-Negative Breast Cancer. |
| title_full | Triple-Negative Breast Cancer. |
| title_fullStr | Triple-Negative Breast Cancer. |
| title_full_unstemmed | Triple-Negative Breast Cancer. |
| title_short | Triple-Negative Breast Cancer. |
| title_sort | triple negative breast cancer |
| topic | Breast Cancer. http://id.loc.gov/authorities/subjects/sh85016679 Breast Neoplasms https://id.nlm.nih.gov/mesh/D001943 Sein Cancer. HEALTH & FITNESS Diseases General. bisacsh MEDICAL Clinical Medicine. bisacsh MEDICAL Diseases. bisacsh MEDICAL Evidence-Based Medicine. bisacsh MEDICAL Internal Medicine. bisacsh Breast Cancer fast |
| topic_facet | Breast Cancer. Breast Neoplasms Sein Cancer. HEALTH & FITNESS Diseases General. MEDICAL Clinical Medicine. MEDICAL Diseases. MEDICAL Evidence-Based Medicine. MEDICAL Internal Medicine. Breast Cancer |
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