The antibody molecule :: from antitoxins to therapeutic antibodies /
'The Antibody Molecule' follows the extraordinary journey of the medics and scientists who shaped the course of medical advances in the field of immunology which has seen chemists, physicists and biologists alike seeking to unravel the most complex system in the human body outside the brai...
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Oxford :
Oxford University Press,
2015.
|
| Ausgabe: | First edition. |
| Schriftenreihe: | Oxford medical histories.
|
| Schlagworte: | |
| Online-Zugang: | DE-862 DE-863 |
| Zusammenfassung: | 'The Antibody Molecule' follows the extraordinary journey of the medics and scientists who shaped the course of medical advances in the field of immunology which has seen chemists, physicists and biologists alike seeking to unravel the most complex system in the human body outside the brain. This title charts its intriguing history, from the genetic basis of antibody diversity to breakthroughs in crystallography and the exploitation of immunoglobulins as therapeutic platforms to treat cancer, inflammation and allergy. |
| Beschreibung: | 1 online resource |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9780191016158 0191016152 |
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| 505 | 0 | |a Cover; The Antibody Molecule; Copyright; Dedication; Contents; Abbreviations; 1 Antibody pre-history: The emergence of empirical immunology; 2 Pre-molecular immunology: The dawn of mechanism; 3 Structural chemistry: Locks, keys, and colloids; 4 The foundations of antibody-antigen recognition emerge; 5 The cellular reformation; 6 The molecular path unfolds; 7 Uncovering the origins of antibody diversity; 8 Immunoglobulin constant regions; 9 Effector functions of constant regions; 10 Transmission and catabolism of IgG; 11 The structural context of antibody diversity | |
| 505 | 8 | |a 12 Monoclonal antibodies and the mechanisms of hypermutation13 Antibody structure prediction and development of humanization strategies ; 14 Antibody engineering: Improving on natural immunity; 15 Therapeutic antibodies: Case study I: Prevention of respiratory syncytial virus illness; 16 Therapeutic antibodies: Case study II: Targeting breast cancer; 17 Antibodies: The therapeutic future; Author Index; Subject Index | |
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| contents | Cover; The Antibody Molecule; Copyright; Dedication; Contents; Abbreviations; 1 Antibody pre-history: The emergence of empirical immunology; 2 Pre-molecular immunology: The dawn of mechanism; 3 Structural chemistry: Locks, keys, and colloids; 4 The foundations of antibody-antigen recognition emerge; 5 The cellular reformation; 6 The molecular path unfolds; 7 Uncovering the origins of antibody diversity; 8 Immunoglobulin constant regions; 9 Effector functions of constant regions; 10 Transmission and catabolism of IgG; 11 The structural context of antibody diversity 12 Monoclonal antibodies and the mechanisms of hypermutation13 Antibody structure prediction and development of humanization strategies ; 14 Antibody engineering: Improving on natural immunity; 15 Therapeutic antibodies: Case study I: Prevention of respiratory syncytial virus illness; 16 Therapeutic antibodies: Case study II: Targeting breast cancer; 17 Antibodies: The therapeutic future; Author Index; Subject Index |
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| spelling | Rees, Anthony R., author. http://id.loc.gov/authorities/names/n85120727 The antibody molecule : from antitoxins to therapeutic antibodies / Anthony R. Rees. First edition. Oxford : Oxford University Press, 2015. 1 online resource text txt rdacontent computer c rdamedia online resource cr rdacarrier Oxford medical histories Print version record. Includes bibliographical references and index. 'The Antibody Molecule' follows the extraordinary journey of the medics and scientists who shaped the course of medical advances in the field of immunology which has seen chemists, physicists and biologists alike seeking to unravel the most complex system in the human body outside the brain. This title charts its intriguing history, from the genetic basis of antibody diversity to breakthroughs in crystallography and the exploitation of immunoglobulins as therapeutic platforms to treat cancer, inflammation and allergy. Cover; The Antibody Molecule; Copyright; Dedication; Contents; Abbreviations; 1 Antibody pre-history: The emergence of empirical immunology; 2 Pre-molecular immunology: The dawn of mechanism; 3 Structural chemistry: Locks, keys, and colloids; 4 The foundations of antibody-antigen recognition emerge; 5 The cellular reformation; 6 The molecular path unfolds; 7 Uncovering the origins of antibody diversity; 8 Immunoglobulin constant regions; 9 Effector functions of constant regions; 10 Transmission and catabolism of IgG; 11 The structural context of antibody diversity 12 Monoclonal antibodies and the mechanisms of hypermutation13 Antibody structure prediction and development of humanization strategies ; 14 Antibody engineering: Improving on natural immunity; 15 Therapeutic antibodies: Case study I: Prevention of respiratory syncytial virus illness; 16 Therapeutic antibodies: Case study II: Targeting breast cancer; 17 Antibodies: The therapeutic future; Author Index; Subject Index Immunoglobulins. http://id.loc.gov/authorities/subjects/sh85064568 Immunology History. Immunoglobulins Immunologie Histoire. Immunoglobulines. SCIENCE Life Sciences Anatomy & Physiology. bisacsh Immunoglobulins fast Immunology fast History fast has work: The antibody molecule (Text) https://id.oclc.org/worldcat/entity/E39PCGfWWhPKq77gqtcRVW7vHC https://id.oclc.org/worldcat/ontology/hasWork Print version: Rees, Anthony R. Antibody molecule 9780199646579 (OCoLC)891658333 Oxford medical histories. http://id.loc.gov/authorities/names/no2013087616 |
| spellingShingle | Rees, Anthony R. The antibody molecule : from antitoxins to therapeutic antibodies / Oxford medical histories. Cover; The Antibody Molecule; Copyright; Dedication; Contents; Abbreviations; 1 Antibody pre-history: The emergence of empirical immunology; 2 Pre-molecular immunology: The dawn of mechanism; 3 Structural chemistry: Locks, keys, and colloids; 4 The foundations of antibody-antigen recognition emerge; 5 The cellular reformation; 6 The molecular path unfolds; 7 Uncovering the origins of antibody diversity; 8 Immunoglobulin constant regions; 9 Effector functions of constant regions; 10 Transmission and catabolism of IgG; 11 The structural context of antibody diversity 12 Monoclonal antibodies and the mechanisms of hypermutation13 Antibody structure prediction and development of humanization strategies ; 14 Antibody engineering: Improving on natural immunity; 15 Therapeutic antibodies: Case study I: Prevention of respiratory syncytial virus illness; 16 Therapeutic antibodies: Case study II: Targeting breast cancer; 17 Antibodies: The therapeutic future; Author Index; Subject Index Immunoglobulins. http://id.loc.gov/authorities/subjects/sh85064568 Immunology History. Immunoglobulins Immunologie Histoire. Immunoglobulines. SCIENCE Life Sciences Anatomy & Physiology. bisacsh Immunoglobulins fast Immunology fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85064568 |
| title | The antibody molecule : from antitoxins to therapeutic antibodies / |
| title_auth | The antibody molecule : from antitoxins to therapeutic antibodies / |
| title_exact_search | The antibody molecule : from antitoxins to therapeutic antibodies / |
| title_full | The antibody molecule : from antitoxins to therapeutic antibodies / Anthony R. Rees. |
| title_fullStr | The antibody molecule : from antitoxins to therapeutic antibodies / Anthony R. Rees. |
| title_full_unstemmed | The antibody molecule : from antitoxins to therapeutic antibodies / Anthony R. Rees. |
| title_short | The antibody molecule : |
| title_sort | antibody molecule from antitoxins to therapeutic antibodies |
| title_sub | from antitoxins to therapeutic antibodies / |
| topic | Immunoglobulins. http://id.loc.gov/authorities/subjects/sh85064568 Immunology History. Immunoglobulins Immunologie Histoire. Immunoglobulines. SCIENCE Life Sciences Anatomy & Physiology. bisacsh Immunoglobulins fast Immunology fast |
| topic_facet | Immunoglobulins. Immunology History. Immunoglobulins Immunologie Histoire. Immunoglobulines. SCIENCE Life Sciences Anatomy & Physiology. Immunology History |
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