From X-rays to DNA :: how engineering drives biology /
"Engineering has been an essential collaborator in biological research and breakthroughs in biology are often enabled by technological advances. Decoding the double helix structure of DNA, for example, only became possible after significant advances in such technologies as X-ray diffraction and...
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| Hauptverfasser: | , , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge, Massachusetts :
The MIT Press,
[2014]
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | "Engineering has been an essential collaborator in biological research and breakthroughs in biology are often enabled by technological advances. Decoding the double helix structure of DNA, for example, only became possible after significant advances in such technologies as X-ray diffraction and gel electrophoresis. Diagnosis and treatment of tuberculosis improved as new technologies -- including the stethoscope, the microscope, and the X-ray -- developed. These engineering breakthroughs take place away from the biology lab, and many years may elapse before the technology becomes available to biologists. In this book, David Lee argues for concurrent engineering -- the convergence of engineering and biological research -- as a means to accelerate the pace of biological discovery and its application to diagnosis and treatment. He presents extensive case studies and introduces a metric to measure the time between technological development and biological discovery. Investigating a series of major biological discoveries that range from pasteurization to electron microscopy, Lee finds that it took an average of forty years for the necessary technology to become available for laboratory use. Lee calls for new approaches to research and funding to encourage a tighter, more collaborative coupling of engineering and biology. Only then, he argues, will we see the rapid advances in the life sciences that are critically needed for life-saving diagnosis and treatment." |
| Beschreibung: | 1 online resource (xii, 233 pages) : illustrations |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9781461952183 1461952182 9780262318389 0262318385 9780262318396 0262318393 1306140668 9781306140669 |
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| 100 | 1 | |a Lee, W. David, |d 1946- |e author. |1 https://id.oclc.org/worldcat/entity/E39PCjDyV9d8hfBRpKfQBGCh9C |0 http://id.loc.gov/authorities/names/n2013027755 | |
| 245 | 1 | 0 | |a From X-rays to DNA : |b how engineering drives biology / |c W. David Lee, with Jeffrey Drazen, Phillip A. Sharp, and Robert S. Langer. |
| 264 | 1 | |a Cambridge, Massachusetts : |b The MIT Press, |c [2014] | |
| 264 | 4 | |c ©201 4 | |
| 300 | |a 1 online resource (xii, 233 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a An opportunity for greater discovery -- Concurrent engineering and science -- Engineering and the engineer -- Discovery of chromosomes and the submicrometer microscope -- DNA: gels, paper, and columns -- Structure of DNA and proteins: X-ray diffraction -- Observing DNA and protein in action: radioisotope labels -- Transcription and electron microscopy -- Protein and DNA automated sequencing -- Concurrent versus nonconcurrent engineering -- The engineers and scientists of concurrent engineering -- Institutions and teams for concurrent biology engineering -- Concurrent engineering in the clinic -- Unmet needs: mapping and understanding cell signaling -- Unmet needs: cancer example -- Summing up. | |
| 520 | 3 | |a "Engineering has been an essential collaborator in biological research and breakthroughs in biology are often enabled by technological advances. Decoding the double helix structure of DNA, for example, only became possible after significant advances in such technologies as X-ray diffraction and gel electrophoresis. Diagnosis and treatment of tuberculosis improved as new technologies -- including the stethoscope, the microscope, and the X-ray -- developed. These engineering breakthroughs take place away from the biology lab, and many years may elapse before the technology becomes available to biologists. In this book, David Lee argues for concurrent engineering -- the convergence of engineering and biological research -- as a means to accelerate the pace of biological discovery and its application to diagnosis and treatment. He presents extensive case studies and introduces a metric to measure the time between technological development and biological discovery. Investigating a series of major biological discoveries that range from pasteurization to electron microscopy, Lee finds that it took an average of forty years for the necessary technology to become available for laboratory use. Lee calls for new approaches to research and funding to encourage a tighter, more collaborative coupling of engineering and biology. Only then, he argues, will we see the rapid advances in the life sciences that are critically needed for life-saving diagnosis and treatment." | |
| 650 | 0 | |a Biomedical engineering. |0 http://id.loc.gov/authorities/subjects/sh85014237 | |
| 650 | 0 | |a Medicine |x Research |x History. | |
| 650 | 0 | |a Medical instruments and apparatus |x Technological innovations. | |
| 650 | 0 | |a Surgical instruments and apparatus |x Technological innovations. | |
| 650 | 1 | 2 | |a Biomedical Engineering |
| 650 | 2 | |a Biomedical Technology |0 https://id.nlm.nih.gov/mesh/D020811 | |
| 650 | 6 | |a Génie biomédical. | |
| 650 | 6 | |a Médecine |x Recherche |x Histoire. | |
| 650 | 6 | |a Médecine |x Appareils et instruments |x Innovations. | |
| 650 | 6 | |a Chirurgie |x Appareils et matériel |x Innovations. | |
| 650 | 7 | |a biomedical engineering. |2 aat | |
| 650 | 7 | |a HEALTH & FITNESS |x Holism. |2 bisacsh | |
| 650 | 7 | |a HEALTH & FITNESS |x Reference. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Alternative Medicine. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Atlases. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Essays. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Family & General Practice. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Holistic Medicine. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Osteopathy. |2 bisacsh | |
| 650 | 7 | |a Biomedical engineering |2 fast | |
| 650 | 7 | |a Medical instruments and apparatus |x Technological innovations |2 fast | |
| 650 | 7 | |a Medicine |x Research |2 fast | |
| 653 | |a BIOMEDICAL SCIENCES/General | ||
| 653 | |a INFORMATION SCIENCE/Technology & Policy | ||
| 655 | 7 | |a History |2 fast | |
| 700 | 1 | |a Drazen, Jeffrey M., |d 1946- |e author. |1 https://id.oclc.org/worldcat/entity/E39PBJfGXKRKWMtyJFQrdKMByd |0 http://id.loc.gov/authorities/names/n98801648 | |
| 700 | 1 | |a Sharp, Phillip A., |e author. |0 http://id.loc.gov/authorities/names/n85304099 | |
| 700 | 1 | |a Langer, Robert S., |e author. |0 http://id.loc.gov/authorities/names/n83238355 | |
| 758 | |i has work: |a From X-rays to DNA (Text) |1 https://id.oclc.org/worldcat/entity/E39PCG86WjBD7DTPxrHfGdwmYd |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Lee, David W., 1946- |t From X-rays to DNA |z 9780262019774 |w (DLC) 2013009442 |w (OCoLC)842500023 |
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Datensatz im Suchindex
| DE-BY-FWS_katkey | ZDB-4-EBA-ocn863157576 |
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| _version_ | 1816882251153014784 |
| adam_text | |
| any_adam_object | |
| author | Lee, W. David, 1946- Drazen, Jeffrey M., 1946- Sharp, Phillip A. Langer, Robert S. |
| author_GND | http://id.loc.gov/authorities/names/n2013027755 http://id.loc.gov/authorities/names/n98801648 http://id.loc.gov/authorities/names/n85304099 http://id.loc.gov/authorities/names/n83238355 |
| author_facet | Lee, W. David, 1946- Drazen, Jeffrey M., 1946- Sharp, Phillip A. Langer, Robert S. |
| author_role | aut aut aut aut |
| author_sort | Lee, W. David, 1946- |
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| building | Verbundindex |
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| callnumber-first | R - Medicine |
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| callnumber-raw | R856 L383 2014eb |
| callnumber-search | R856 L383 2014eb |
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| collection | ZDB-4-EBA |
| contents | An opportunity for greater discovery -- Concurrent engineering and science -- Engineering and the engineer -- Discovery of chromosomes and the submicrometer microscope -- DNA: gels, paper, and columns -- Structure of DNA and proteins: X-ray diffraction -- Observing DNA and protein in action: radioisotope labels -- Transcription and electron microscopy -- Protein and DNA automated sequencing -- Concurrent versus nonconcurrent engineering -- The engineers and scientists of concurrent engineering -- Institutions and teams for concurrent biology engineering -- Concurrent engineering in the clinic -- Unmet needs: mapping and understanding cell signaling -- Unmet needs: cancer example -- Summing up. |
| ctrlnum | (OCoLC)863157576 |
| dewey-full | 610.28 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 610 - Medicine and health |
| dewey-raw | 610.28 |
| dewey-search | 610.28 |
| dewey-sort | 3610.28 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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| genre | History fast |
| genre_facet | History |
| id | ZDB-4-EBA-ocn863157576 |
| illustrated | Illustrated |
| indexdate | 2024-11-27T13:25:38Z |
| institution | BVB |
| isbn | 9781461952183 1461952182 9780262318389 0262318385 9780262318396 0262318393 1306140668 9781306140669 |
| language | English |
| oclc_num | 863157576 |
| open_access_boolean | |
| owner | MAIN DE-863 DE-BY-FWS |
| owner_facet | MAIN DE-863 DE-BY-FWS |
| physical | 1 online resource (xii, 233 pages) : illustrations |
| psigel | ZDB-4-EBA |
| publishDate | 2014 |
| publishDateSearch | 2014 |
| publishDateSort | 2014 |
| publisher | The MIT Press, |
| record_format | marc |
| spelling | Lee, W. David, 1946- author. https://id.oclc.org/worldcat/entity/E39PCjDyV9d8hfBRpKfQBGCh9C http://id.loc.gov/authorities/names/n2013027755 From X-rays to DNA : how engineering drives biology / W. David Lee, with Jeffrey Drazen, Phillip A. Sharp, and Robert S. Langer. Cambridge, Massachusetts : The MIT Press, [2014] ©201 4 1 online resource (xii, 233 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier Includes bibliographical references and index. Print version record. An opportunity for greater discovery -- Concurrent engineering and science -- Engineering and the engineer -- Discovery of chromosomes and the submicrometer microscope -- DNA: gels, paper, and columns -- Structure of DNA and proteins: X-ray diffraction -- Observing DNA and protein in action: radioisotope labels -- Transcription and electron microscopy -- Protein and DNA automated sequencing -- Concurrent versus nonconcurrent engineering -- The engineers and scientists of concurrent engineering -- Institutions and teams for concurrent biology engineering -- Concurrent engineering in the clinic -- Unmet needs: mapping and understanding cell signaling -- Unmet needs: cancer example -- Summing up. "Engineering has been an essential collaborator in biological research and breakthroughs in biology are often enabled by technological advances. Decoding the double helix structure of DNA, for example, only became possible after significant advances in such technologies as X-ray diffraction and gel electrophoresis. Diagnosis and treatment of tuberculosis improved as new technologies -- including the stethoscope, the microscope, and the X-ray -- developed. These engineering breakthroughs take place away from the biology lab, and many years may elapse before the technology becomes available to biologists. In this book, David Lee argues for concurrent engineering -- the convergence of engineering and biological research -- as a means to accelerate the pace of biological discovery and its application to diagnosis and treatment. He presents extensive case studies and introduces a metric to measure the time between technological development and biological discovery. Investigating a series of major biological discoveries that range from pasteurization to electron microscopy, Lee finds that it took an average of forty years for the necessary technology to become available for laboratory use. Lee calls for new approaches to research and funding to encourage a tighter, more collaborative coupling of engineering and biology. Only then, he argues, will we see the rapid advances in the life sciences that are critically needed for life-saving diagnosis and treatment." Biomedical engineering. http://id.loc.gov/authorities/subjects/sh85014237 Medicine Research History. Medical instruments and apparatus Technological innovations. Surgical instruments and apparatus Technological innovations. Biomedical Engineering Biomedical Technology https://id.nlm.nih.gov/mesh/D020811 Génie biomédical. Médecine Recherche Histoire. Médecine Appareils et instruments Innovations. Chirurgie Appareils et matériel Innovations. biomedical engineering. aat HEALTH & FITNESS Holism. bisacsh HEALTH & FITNESS Reference. bisacsh MEDICAL Alternative Medicine. bisacsh MEDICAL Atlases. bisacsh MEDICAL Essays. bisacsh MEDICAL Family & General Practice. bisacsh MEDICAL Holistic Medicine. bisacsh MEDICAL Osteopathy. bisacsh Biomedical engineering fast Medical instruments and apparatus Technological innovations fast Medicine Research fast BIOMEDICAL SCIENCES/General INFORMATION SCIENCE/Technology & Policy History fast Drazen, Jeffrey M., 1946- author. https://id.oclc.org/worldcat/entity/E39PBJfGXKRKWMtyJFQrdKMByd http://id.loc.gov/authorities/names/n98801648 Sharp, Phillip A., author. http://id.loc.gov/authorities/names/n85304099 Langer, Robert S., author. http://id.loc.gov/authorities/names/n83238355 has work: From X-rays to DNA (Text) https://id.oclc.org/worldcat/entity/E39PCG86WjBD7DTPxrHfGdwmYd https://id.oclc.org/worldcat/ontology/hasWork Print version: Lee, David W., 1946- From X-rays to DNA 9780262019774 (DLC) 2013009442 (OCoLC)842500023 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=663529 Volltext |
| spellingShingle | Lee, W. David, 1946- Drazen, Jeffrey M., 1946- Sharp, Phillip A. Langer, Robert S. From X-rays to DNA : how engineering drives biology / An opportunity for greater discovery -- Concurrent engineering and science -- Engineering and the engineer -- Discovery of chromosomes and the submicrometer microscope -- DNA: gels, paper, and columns -- Structure of DNA and proteins: X-ray diffraction -- Observing DNA and protein in action: radioisotope labels -- Transcription and electron microscopy -- Protein and DNA automated sequencing -- Concurrent versus nonconcurrent engineering -- The engineers and scientists of concurrent engineering -- Institutions and teams for concurrent biology engineering -- Concurrent engineering in the clinic -- Unmet needs: mapping and understanding cell signaling -- Unmet needs: cancer example -- Summing up. Biomedical engineering. http://id.loc.gov/authorities/subjects/sh85014237 Medicine Research History. Medical instruments and apparatus Technological innovations. Surgical instruments and apparatus Technological innovations. Biomedical Engineering Biomedical Technology https://id.nlm.nih.gov/mesh/D020811 Génie biomédical. Médecine Recherche Histoire. Médecine Appareils et instruments Innovations. Chirurgie Appareils et matériel Innovations. biomedical engineering. aat HEALTH & FITNESS Holism. bisacsh HEALTH & FITNESS Reference. bisacsh MEDICAL Alternative Medicine. bisacsh MEDICAL Atlases. bisacsh MEDICAL Essays. bisacsh MEDICAL Family & General Practice. bisacsh MEDICAL Holistic Medicine. bisacsh MEDICAL Osteopathy. bisacsh Biomedical engineering fast Medical instruments and apparatus Technological innovations fast Medicine Research fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85014237 https://id.nlm.nih.gov/mesh/D020811 |
| title | From X-rays to DNA : how engineering drives biology / |
| title_auth | From X-rays to DNA : how engineering drives biology / |
| title_exact_search | From X-rays to DNA : how engineering drives biology / |
| title_full | From X-rays to DNA : how engineering drives biology / W. David Lee, with Jeffrey Drazen, Phillip A. Sharp, and Robert S. Langer. |
| title_fullStr | From X-rays to DNA : how engineering drives biology / W. David Lee, with Jeffrey Drazen, Phillip A. Sharp, and Robert S. Langer. |
| title_full_unstemmed | From X-rays to DNA : how engineering drives biology / W. David Lee, with Jeffrey Drazen, Phillip A. Sharp, and Robert S. Langer. |
| title_short | From X-rays to DNA : |
| title_sort | from x rays to dna how engineering drives biology |
| title_sub | how engineering drives biology / |
| topic | Biomedical engineering. http://id.loc.gov/authorities/subjects/sh85014237 Medicine Research History. Medical instruments and apparatus Technological innovations. Surgical instruments and apparatus Technological innovations. Biomedical Engineering Biomedical Technology https://id.nlm.nih.gov/mesh/D020811 Génie biomédical. Médecine Recherche Histoire. Médecine Appareils et instruments Innovations. Chirurgie Appareils et matériel Innovations. biomedical engineering. aat HEALTH & FITNESS Holism. bisacsh HEALTH & FITNESS Reference. bisacsh MEDICAL Alternative Medicine. bisacsh MEDICAL Atlases. bisacsh MEDICAL Essays. bisacsh MEDICAL Family & General Practice. bisacsh MEDICAL Holistic Medicine. bisacsh MEDICAL Osteopathy. bisacsh Biomedical engineering fast Medical instruments and apparatus Technological innovations fast Medicine Research fast |
| topic_facet | Biomedical engineering. Medicine Research History. Medical instruments and apparatus Technological innovations. Surgical instruments and apparatus Technological innovations. Biomedical Engineering Biomedical Technology Génie biomédical. Médecine Recherche Histoire. Médecine Appareils et instruments Innovations. Chirurgie Appareils et matériel Innovations. biomedical engineering. HEALTH & FITNESS Holism. HEALTH & FITNESS Reference. MEDICAL Alternative Medicine. MEDICAL Atlases. MEDICAL Essays. MEDICAL Family & General Practice. MEDICAL Holistic Medicine. MEDICAL Osteopathy. Biomedical engineering Medical instruments and apparatus Technological innovations Medicine Research History |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=663529 |
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