Impedimetric biosensors for medical applications :: current progress and challenges /
In this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric bi...
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| Hauptverfasser: | , , , , , |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY :
ASME Press : Momentum Press,
[2013]
|
| Schriftenreihe: | Biomedical & nanomedical technologies.
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | In this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric biosensors and the principles of electrochemical impedance spectroscopy. Next, the current state-of-the art in terms of the science and technology underpinning impedance-based biosensors is reviewed in detail. The layer- by-layer construction of impedimetric sensors is described, including the design of electrodes, their nano-modification, transducer surface functionalisation and the attachment of different bioreceptors. The current challenges of translating lab-based biosensor platforms into commercially-available devices that function with real patient samples at the POC are presented; this includes a consideration of systems integration, microfluidics and biosensor regeneration. The final section of this monograph describes case studies of successful impedance-based biosensors for the detection of a range of analytes from small molecules up to whole microorganisms. Finally, the authors put forward future perspectives for the clinical applications of impedimetric biosensors. |
| Beschreibung: | 1 online resource (70 pages) : illustrations |
| Bibliographie: | Includes bibliographical references (pages 57-70). |
| ISBN: | 9781606506370 1606506374 1606506366 9781606506363 |
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| 100 | 1 | |a Rushworth, Jo V., |e author. | |
| 245 | 1 | 0 | |a Impedimetric biosensors for medical applications : |b current progress and challenges / |c Jo V. Rushworth, Natalie A. Hirst, Jack A. Goode, Douglas J. Pike, Asif Ahmed, Paul A. Millner. |
| 264 | 1 | |a New York, NY : |b ASME Press : |b Momentum Press, |c [2013] | |
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| 490 | 1 | |a Biomedical and nanomedical technologies | |
| 504 | |a Includes bibliographical references (pages 57-70). | ||
| 505 | 0 | |a 1. Introduction and scope. | |
| 505 | 8 | |a 2. Biosensors -- 2.1 Brief history of biosensor development -- 2.2 Applications of biosensors -- 2.3 Biosensor architecture, an overview -- 2.4 Biorecognition element -- 2.5 Transducer element -- 2.6 Summary. | |
| 505 | 8 | |a 3. Electrochemical impedance spectroscopy -- 3.1 Brief history of the development of impedimetric biosensors -- 3.2 An overview of impedance -- 3.3 Principles of impedimetric sensing -- 3.4 Presenting and analysing impedance data. | |
| 505 | 8 | |a 4. Fabrication of impedimetric biosensors -- 4.1 Electrode design and materials -- 4.2 Bioreceptor tethering to transducer surfaces. | |
| 505 | 8 | |a 5. Commercializing impedimetric biosensors: from laboratory to field -- 5.1 Components of a point-of-care diagnostic device -- 5.2 From research to point-of-care -- 5.3 Sample delivery & processing -- 5.4 Sensor regeneration -- 5.5 Barriers to commercialisation. | |
| 505 | 8 | |a 6. Case studies of impedimetric biosensors for medical applications -- 6.1 Whole cells and pathogenic microorganisms -- 6.2 Protein and peptide biomarkers of disease -- 6.3 Small molecules. | |
| 505 | 8 | |a 7. Conclusions and future perspectives. | |
| 505 | 8 | |a 8. Author biographies -- References. | |
| 520 | 3 | |a In this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric biosensors and the principles of electrochemical impedance spectroscopy. Next, the current state-of-the art in terms of the science and technology underpinning impedance-based biosensors is reviewed in detail. The layer- by-layer construction of impedimetric sensors is described, including the design of electrodes, their nano-modification, transducer surface functionalisation and the attachment of different bioreceptors. The current challenges of translating lab-based biosensor platforms into commercially-available devices that function with real patient samples at the POC are presented; this includes a consideration of systems integration, microfluidics and biosensor regeneration. The final section of this monograph describes case studies of successful impedance-based biosensors for the detection of a range of analytes from small molecules up to whole microorganisms. Finally, the authors put forward future perspectives for the clinical applications of impedimetric biosensors. | |
| 588 | 0 | |a Print version record. | |
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| 650 | 0 | |a Impedance spectroscopy. |0 http://id.loc.gov/authorities/subjects/sh86007880 | |
| 650 | 2 | |a Biosensing Techniques | |
| 650 | 2 | |a Electric Impedance | |
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| 650 | 7 | |a Biosensors |2 fast | |
| 650 | 7 | |a Impedance spectroscopy |2 fast | |
| 700 | 1 | |a Hirst, Natalie A., |e author. | |
| 700 | 1 | |a Goode, Jack A., |e author. | |
| 700 | 1 | |a Pike, Douglas J., |e author. | |
| 700 | 1 | |a Ahmed, Asif, |e author. |0 http://id.loc.gov/authorities/names/n2011038103 | |
| 700 | 1 | |a Millner, Paul A., |e author. | |
| 776 | 0 | 8 | |i Print version: |a Rushworth, Jo V. |t Impedimetric biosensors for medical applications. |d New York, NY : ASME Press : Momentum Press, [2013] |z 9780791860243 |w (OCoLC)864090477 |
| 830 | 0 | |a Biomedical & nanomedical technologies. |0 http://id.loc.gov/authorities/names/n2013180695 | |
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| author | Rushworth, Jo V. Hirst, Natalie A. Goode, Jack A. Pike, Douglas J. Ahmed, Asif Millner, Paul A. |
| author_GND | http://id.loc.gov/authorities/names/n2011038103 |
| author_facet | Rushworth, Jo V. Hirst, Natalie A. Goode, Jack A. Pike, Douglas J. Ahmed, Asif Millner, Paul A. |
| author_role | aut aut aut aut aut aut |
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| contents | 1. Introduction and scope. 2. Biosensors -- 2.1 Brief history of biosensor development -- 2.2 Applications of biosensors -- 2.3 Biosensor architecture, an overview -- 2.4 Biorecognition element -- 2.5 Transducer element -- 2.6 Summary. 3. Electrochemical impedance spectroscopy -- 3.1 Brief history of the development of impedimetric biosensors -- 3.2 An overview of impedance -- 3.3 Principles of impedimetric sensing -- 3.4 Presenting and analysing impedance data. 4. Fabrication of impedimetric biosensors -- 4.1 Electrode design and materials -- 4.2 Bioreceptor tethering to transducer surfaces. 5. Commercializing impedimetric biosensors: from laboratory to field -- 5.1 Components of a point-of-care diagnostic device -- 5.2 From research to point-of-care -- 5.3 Sample delivery & processing -- 5.4 Sensor regeneration -- 5.5 Barriers to commercialisation. 6. Case studies of impedimetric biosensors for medical applications -- 6.1 Whole cells and pathogenic microorganisms -- 6.2 Protein and peptide biomarkers of disease -- 6.3 Small molecules. 7. Conclusions and future perspectives. 8. Author biographies -- References. |
| ctrlnum | (OCoLC)862114877 |
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| discipline | Medizin |
| format | Electronic eBook |
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| id | ZDB-4-EBA-ocn862114877 |
| illustrated | Illustrated |
| indexdate | 2024-11-27T13:25:37Z |
| institution | BVB |
| isbn | 9781606506370 1606506374 1606506366 9781606506363 |
| language | English |
| oclc_num | 862114877 |
| open_access_boolean | |
| owner | MAIN DE-863 DE-BY-FWS |
| owner_facet | MAIN DE-863 DE-BY-FWS |
| physical | 1 online resource (70 pages) : illustrations |
| psigel | ZDB-4-EBA |
| publishDate | 2013 |
| publishDateSearch | 2013 |
| publishDateSort | 2013 |
| publisher | ASME Press : Momentum Press, |
| record_format | marc |
| series | Biomedical & nanomedical technologies. |
| series2 | Biomedical and nanomedical technologies |
| spelling | Rushworth, Jo V., author. Impedimetric biosensors for medical applications : current progress and challenges / Jo V. Rushworth, Natalie A. Hirst, Jack A. Goode, Douglas J. Pike, Asif Ahmed, Paul A. Millner. New York, NY : ASME Press : Momentum Press, [2013] 1 online resource (70 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier Biomedical and nanomedical technologies Includes bibliographical references (pages 57-70). 1. Introduction and scope. 2. Biosensors -- 2.1 Brief history of biosensor development -- 2.2 Applications of biosensors -- 2.3 Biosensor architecture, an overview -- 2.4 Biorecognition element -- 2.5 Transducer element -- 2.6 Summary. 3. Electrochemical impedance spectroscopy -- 3.1 Brief history of the development of impedimetric biosensors -- 3.2 An overview of impedance -- 3.3 Principles of impedimetric sensing -- 3.4 Presenting and analysing impedance data. 4. Fabrication of impedimetric biosensors -- 4.1 Electrode design and materials -- 4.2 Bioreceptor tethering to transducer surfaces. 5. Commercializing impedimetric biosensors: from laboratory to field -- 5.1 Components of a point-of-care diagnostic device -- 5.2 From research to point-of-care -- 5.3 Sample delivery & processing -- 5.4 Sensor regeneration -- 5.5 Barriers to commercialisation. 6. Case studies of impedimetric biosensors for medical applications -- 6.1 Whole cells and pathogenic microorganisms -- 6.2 Protein and peptide biomarkers of disease -- 6.3 Small molecules. 7. Conclusions and future perspectives. 8. Author biographies -- References. In this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric biosensors and the principles of electrochemical impedance spectroscopy. Next, the current state-of-the art in terms of the science and technology underpinning impedance-based biosensors is reviewed in detail. The layer- by-layer construction of impedimetric sensors is described, including the design of electrodes, their nano-modification, transducer surface functionalisation and the attachment of different bioreceptors. The current challenges of translating lab-based biosensor platforms into commercially-available devices that function with real patient samples at the POC are presented; this includes a consideration of systems integration, microfluidics and biosensor regeneration. The final section of this monograph describes case studies of successful impedance-based biosensors for the detection of a range of analytes from small molecules up to whole microorganisms. Finally, the authors put forward future perspectives for the clinical applications of impedimetric biosensors. Print version record. Biosensors. http://id.loc.gov/authorities/subjects/sh85014260 Impedance spectroscopy. http://id.loc.gov/authorities/subjects/sh86007880 Biosensing Techniques Electric Impedance Biocapteurs. Spectroscopie d'impédance. HEALTH & FITNESS Holism. bisacsh HEALTH & FITNESS Reference. bisacsh MEDICAL Alternative Medicine. bisacsh MEDICAL Atlases. bisacsh MEDICAL Essays. bisacsh MEDICAL Family & General Practice. bisacsh MEDICAL Holistic Medicine. bisacsh MEDICAL Osteopathy. bisacsh Biosensors fast Impedance spectroscopy fast Hirst, Natalie A., author. Goode, Jack A., author. Pike, Douglas J., author. Ahmed, Asif, author. http://id.loc.gov/authorities/names/n2011038103 Millner, Paul A., author. Print version: Rushworth, Jo V. Impedimetric biosensors for medical applications. New York, NY : ASME Press : Momentum Press, [2013] 9780791860243 (OCoLC)864090477 Biomedical & nanomedical technologies. http://id.loc.gov/authorities/names/n2013180695 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=653952 Volltext |
| spellingShingle | Rushworth, Jo V. Hirst, Natalie A. Goode, Jack A. Pike, Douglas J. Ahmed, Asif Millner, Paul A. Impedimetric biosensors for medical applications : current progress and challenges / Biomedical & nanomedical technologies. 1. Introduction and scope. 2. Biosensors -- 2.1 Brief history of biosensor development -- 2.2 Applications of biosensors -- 2.3 Biosensor architecture, an overview -- 2.4 Biorecognition element -- 2.5 Transducer element -- 2.6 Summary. 3. Electrochemical impedance spectroscopy -- 3.1 Brief history of the development of impedimetric biosensors -- 3.2 An overview of impedance -- 3.3 Principles of impedimetric sensing -- 3.4 Presenting and analysing impedance data. 4. Fabrication of impedimetric biosensors -- 4.1 Electrode design and materials -- 4.2 Bioreceptor tethering to transducer surfaces. 5. Commercializing impedimetric biosensors: from laboratory to field -- 5.1 Components of a point-of-care diagnostic device -- 5.2 From research to point-of-care -- 5.3 Sample delivery & processing -- 5.4 Sensor regeneration -- 5.5 Barriers to commercialisation. 6. Case studies of impedimetric biosensors for medical applications -- 6.1 Whole cells and pathogenic microorganisms -- 6.2 Protein and peptide biomarkers of disease -- 6.3 Small molecules. 7. Conclusions and future perspectives. 8. Author biographies -- References. Biosensors. http://id.loc.gov/authorities/subjects/sh85014260 Impedance spectroscopy. http://id.loc.gov/authorities/subjects/sh86007880 Biosensing Techniques Electric Impedance Biocapteurs. Spectroscopie d'impédance. HEALTH & FITNESS Holism. bisacsh HEALTH & FITNESS Reference. bisacsh MEDICAL Alternative Medicine. bisacsh MEDICAL Atlases. bisacsh MEDICAL Essays. bisacsh MEDICAL Family & General Practice. bisacsh MEDICAL Holistic Medicine. bisacsh MEDICAL Osteopathy. bisacsh Biosensors fast Impedance spectroscopy fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85014260 http://id.loc.gov/authorities/subjects/sh86007880 |
| title | Impedimetric biosensors for medical applications : current progress and challenges / |
| title_auth | Impedimetric biosensors for medical applications : current progress and challenges / |
| title_exact_search | Impedimetric biosensors for medical applications : current progress and challenges / |
| title_full | Impedimetric biosensors for medical applications : current progress and challenges / Jo V. Rushworth, Natalie A. Hirst, Jack A. Goode, Douglas J. Pike, Asif Ahmed, Paul A. Millner. |
| title_fullStr | Impedimetric biosensors for medical applications : current progress and challenges / Jo V. Rushworth, Natalie A. Hirst, Jack A. Goode, Douglas J. Pike, Asif Ahmed, Paul A. Millner. |
| title_full_unstemmed | Impedimetric biosensors for medical applications : current progress and challenges / Jo V. Rushworth, Natalie A. Hirst, Jack A. Goode, Douglas J. Pike, Asif Ahmed, Paul A. Millner. |
| title_short | Impedimetric biosensors for medical applications : |
| title_sort | impedimetric biosensors for medical applications current progress and challenges |
| title_sub | current progress and challenges / |
| topic | Biosensors. http://id.loc.gov/authorities/subjects/sh85014260 Impedance spectroscopy. http://id.loc.gov/authorities/subjects/sh86007880 Biosensing Techniques Electric Impedance Biocapteurs. Spectroscopie d'impédance. HEALTH & FITNESS Holism. bisacsh HEALTH & FITNESS Reference. bisacsh MEDICAL Alternative Medicine. bisacsh MEDICAL Atlases. bisacsh MEDICAL Essays. bisacsh MEDICAL Family & General Practice. bisacsh MEDICAL Holistic Medicine. bisacsh MEDICAL Osteopathy. bisacsh Biosensors fast Impedance spectroscopy fast |
| topic_facet | Biosensors. Impedance spectroscopy. Biosensing Techniques Electric Impedance Biocapteurs. Spectroscopie d'impédance. HEALTH & FITNESS Holism. HEALTH & FITNESS Reference. MEDICAL Alternative Medicine. MEDICAL Atlases. MEDICAL Essays. MEDICAL Family & General Practice. MEDICAL Holistic Medicine. MEDICAL Osteopathy. Biosensors Impedance spectroscopy |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=653952 |
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