Animal models for the study of human disease /:
Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed informat...
Gespeichert in:
Weitere Verfasser: | |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Amsterdam :
Elsevier/Academic Press,
2013.
|
Ausgabe: | First edition. |
Schlagworte: | |
Online-Zugang: | Volltext Volltext |
Zusammenfassung: | Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine. The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, and cancer. |
Beschreibung: | 1 online resource (xviii, 1089 pages) : illustrations |
Bibliographie: | Includes bibliographical references and index. |
ISBN: | 9780124159129 0124159125 1299642276 9781299642270 0124158943 9780124158948 |
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245 | 0 | 0 | |a Animal models for the study of human disease / |c edited by P. Michael Conn. |
250 | |a First edition. | ||
264 | 1 | |a Amsterdam : |b Elsevier/Academic Press, |c 2013. | |
300 | |a 1 online resource (xviii, 1089 pages) : |b illustrations | ||
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520 | |a Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine. The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, and cancer. | ||
504 | |a Includes bibliographical references and index. | ||
588 | 0 | |a Online resource; title from electronic title page (ebrary, viewed on February 18, 2014). | |
505 | 0 | |a Front Cover; ANIMAL MODELS FOR THE STUDY OF HUMAN DISEASE; Copyright; Contents; Preface; List of Contributors; Part I -ETHICS, RESOURCES AND APPROACHES; Chapter 1 -- Ethics in Biomedical Animal Research: The Key Role of the Investigator; NATURE AND SCOPE OF THE CHAPTER; THE SUBJECT MATTER OF ANIMAL RESEARCH ETHICS; ASPECTS OF ANIMAL USE AND CARE RELEVANT TO ANIMAL RESEARCH ETHICS; WHY INVESTIGATORS ARE UNIQUELY QUALIFIED TO ENGAGE IN ETHICAL ASSESSMENT OF ANIMAL RESEARCH; WHY INVESTIGATORS SHOULD COMMIT THEMSELVES TO ETHICAL CONDUCT OF ANIMAL RESEARCH. | |
505 | 8 | |a WHY INVESTIGATORS PLAY THE KEY ROLE IN ASSURING THE ETHICAL CONDUCT OF ANIMAL RESEARCH PROJECTSSOURCES OF SUPPORT AND GUIDANCE IN CONDUCTING ETHICAL RESEARCH; DEVELOPING USEFUL ETHICAL GUIDELINES; FUNDAMENTAL PRINCIPLES OF ANIMAL RESEARCH ETHICS; PRACTICAL ETHICAL GUIDELINES FOR INVESTIGATORS; SOME CURRENT DIFFICULT ISSUES IN ANIMAL RESEARCH ETHICS; GENERAL SUGGESTIONS FOR INVESTIGATORS; References; Chapter 2 -- Access to Resources: A Model Organism Database for Humans; THE PROBLEM; THE LAMHDI SOLUTION; THE IDEAL SOLUTION; Acknowledgments; References. | |
505 | 8 | |a Chapter 3 -- The Advent of the Golden Era of Animal AlternativesINTRODUCTION; ANALYTICAL TOOLS FOR THE DETECTION OF FOOD-BORNE DISEASE; AN IN VITRO SYSTEM TO ASSESS ADVERSE EFFECTS DURING DEVELOPMENT; DISEASES-IN-A-DISH; NONINVASIVE IMAGING AND RECORDING; CONCLUSIONS; References; Chapter 4 -- Environmental Enrichment for Animals Used in Research; INTRODUCTION; APPLIED SCIENCE: ENRICHMENT AS A WELFARE TOOL; BASIC SCIENCE: ENRICHMENT AND ANIMAL MODELS; ENRICHMENT AND EXPERIMENTAL VARIABILITY; ENVIRONMENTAL ENRICHMENT REGULATIONS; IMPLEMENTING AN ENRICHMENT PLAN; CONCLUSIONS; Acknowledgments. | |
505 | 8 | |a RETINAL DEGENERATION CAUSED BY MNU IN VARIOUS ANIMAL SPECIESAGE-RELATED PHOTORECEPTOR CELL DAMAGE AND SENSITIVITY TO MNU; PHOTORECEPTOR CELL DEATH, CELL DEBRIS REMOVAL, AND RPE CELL MIGRATION; MOLECULAR MECHANISMS IN PHOTORECEPTOR CELL DEATH CAUSED BY MNU; THERAPEUTIC TRIALS AGAINST MNU-INDUCED PHOTORECEPTOR APOPTOSIS; CONCLUDING REMARKS; Acknowledgments; References; Part III -CARDIAC AND CARDIOVASCULAR; Chapter 7 -- Animal Models of Myocardial Disease; INTRODUCTION; THE SPECTRUM OF CARDIOVASCULAR DISEASE; CHOICE OF ANIMAL SYSTEM; EXPERIMENTAL DESIGN; ISCHEMIC HEART DISEASE. | |
650 | 0 | |a Diseases |x Animal models. |0 http://id.loc.gov/authorities/subjects/sh85038412 | |
650 | 0 | |a Laboratory animals. |0 http://id.loc.gov/authorities/subjects/sh85073746 | |
650 | 0 | |a Pathology, Experimental. |0 http://id.loc.gov/authorities/subjects/sh85098689 | |
650 | 1 | 2 | |a Disease Models, Animal |
650 | 2 | 2 | |a Animal Experimentation |x ethics |
650 | 2 | 2 | |a Animal Use Alternatives |
650 | 2 | 2 | |a Animals, Laboratory |
650 | 6 | |a Maladies |x Modèles animaux. | |
650 | 6 | |a Animaux de laboratoire. | |
650 | 6 | |a Pathologie expérimentale. | |
650 | 7 | |a MEDICAL |x Laboratory Medicine. |2 bisacsh | |
650 | 7 | |a Diseases |x Animal models |2 fast | |
650 | 7 | |a Laboratory animals |2 fast | |
650 | 7 | |a Pathology, Experimental |2 fast | |
700 | 1 | |a Conn, P. Michael, |e editor. | |
776 | 0 | 8 | |i Print version: |t Animal models for the study of human disease. |d London ; Waltham, MA : Elsevier, 2013 |z 9780124158948 |w (DLC) 2013444225 |w (OCoLC)865180615 |
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Datensatz im Suchindex
DE-BY-FWS_katkey | ZDB-4-EBA-ocn847952648 |
---|---|
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adam_text | |
any_adam_object | |
author2 | Conn, P. Michael |
author2_role | edt |
author2_variant | p m c pm pmc |
author_facet | Conn, P. Michael |
building | Verbundindex |
bvnumber | localFWS |
callnumber-first | R - Medicine |
callnumber-label | RB125 |
callnumber-raw | RB125 |
callnumber-search | RB125 |
callnumber-sort | RB 3125 |
callnumber-subject | RB - Pathology |
collection | ZDB-4-EBA |
contents | Front Cover; ANIMAL MODELS FOR THE STUDY OF HUMAN DISEASE; Copyright; Contents; Preface; List of Contributors; Part I -ETHICS, RESOURCES AND APPROACHES; Chapter 1 -- Ethics in Biomedical Animal Research: The Key Role of the Investigator; NATURE AND SCOPE OF THE CHAPTER; THE SUBJECT MATTER OF ANIMAL RESEARCH ETHICS; ASPECTS OF ANIMAL USE AND CARE RELEVANT TO ANIMAL RESEARCH ETHICS; WHY INVESTIGATORS ARE UNIQUELY QUALIFIED TO ENGAGE IN ETHICAL ASSESSMENT OF ANIMAL RESEARCH; WHY INVESTIGATORS SHOULD COMMIT THEMSELVES TO ETHICAL CONDUCT OF ANIMAL RESEARCH. WHY INVESTIGATORS PLAY THE KEY ROLE IN ASSURING THE ETHICAL CONDUCT OF ANIMAL RESEARCH PROJECTSSOURCES OF SUPPORT AND GUIDANCE IN CONDUCTING ETHICAL RESEARCH; DEVELOPING USEFUL ETHICAL GUIDELINES; FUNDAMENTAL PRINCIPLES OF ANIMAL RESEARCH ETHICS; PRACTICAL ETHICAL GUIDELINES FOR INVESTIGATORS; SOME CURRENT DIFFICULT ISSUES IN ANIMAL RESEARCH ETHICS; GENERAL SUGGESTIONS FOR INVESTIGATORS; References; Chapter 2 -- Access to Resources: A Model Organism Database for Humans; THE PROBLEM; THE LAMHDI SOLUTION; THE IDEAL SOLUTION; Acknowledgments; References. Chapter 3 -- The Advent of the Golden Era of Animal AlternativesINTRODUCTION; ANALYTICAL TOOLS FOR THE DETECTION OF FOOD-BORNE DISEASE; AN IN VITRO SYSTEM TO ASSESS ADVERSE EFFECTS DURING DEVELOPMENT; DISEASES-IN-A-DISH; NONINVASIVE IMAGING AND RECORDING; CONCLUSIONS; References; Chapter 4 -- Environmental Enrichment for Animals Used in Research; INTRODUCTION; APPLIED SCIENCE: ENRICHMENT AS A WELFARE TOOL; BASIC SCIENCE: ENRICHMENT AND ANIMAL MODELS; ENRICHMENT AND EXPERIMENTAL VARIABILITY; ENVIRONMENTAL ENRICHMENT REGULATIONS; IMPLEMENTING AN ENRICHMENT PLAN; CONCLUSIONS; Acknowledgments. RETINAL DEGENERATION CAUSED BY MNU IN VARIOUS ANIMAL SPECIESAGE-RELATED PHOTORECEPTOR CELL DAMAGE AND SENSITIVITY TO MNU; PHOTORECEPTOR CELL DEATH, CELL DEBRIS REMOVAL, AND RPE CELL MIGRATION; MOLECULAR MECHANISMS IN PHOTORECEPTOR CELL DEATH CAUSED BY MNU; THERAPEUTIC TRIALS AGAINST MNU-INDUCED PHOTORECEPTOR APOPTOSIS; CONCLUDING REMARKS; Acknowledgments; References; Part III -CARDIAC AND CARDIOVASCULAR; Chapter 7 -- Animal Models of Myocardial Disease; INTRODUCTION; THE SPECTRUM OF CARDIOVASCULAR DISEASE; CHOICE OF ANIMAL SYSTEM; EXPERIMENTAL DESIGN; ISCHEMIC HEART DISEASE. |
ctrlnum | (OCoLC)847952648 |
dewey-full | 619 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 619 - [Unassigned] |
dewey-raw | 619 |
dewey-search | 619 |
dewey-sort | 3619 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
edition | First edition. |
format | Electronic eBook |
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id | ZDB-4-EBA-ocn847952648 |
illustrated | Illustrated |
indexdate | 2024-10-25T16:21:28Z |
institution | BVB |
isbn | 9780124159129 0124159125 1299642276 9781299642270 0124158943 9780124158948 |
language | English |
oclc_num | 847952648 |
open_access_boolean | |
owner | MAIN |
owner_facet | MAIN |
physical | 1 online resource (xviii, 1089 pages) : illustrations |
psigel | ZDB-4-EBA |
publishDate | 2013 |
publishDateSearch | 2013 |
publishDateSort | 2013 |
publisher | Elsevier/Academic Press, |
record_format | marc |
spelling | Animal models for the study of human disease / edited by P. Michael Conn. First edition. Amsterdam : Elsevier/Academic Press, 2013. 1 online resource (xviii, 1089 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier data file rda Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine. The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, and cancer. Includes bibliographical references and index. Online resource; title from electronic title page (ebrary, viewed on February 18, 2014). Front Cover; ANIMAL MODELS FOR THE STUDY OF HUMAN DISEASE; Copyright; Contents; Preface; List of Contributors; Part I -ETHICS, RESOURCES AND APPROACHES; Chapter 1 -- Ethics in Biomedical Animal Research: The Key Role of the Investigator; NATURE AND SCOPE OF THE CHAPTER; THE SUBJECT MATTER OF ANIMAL RESEARCH ETHICS; ASPECTS OF ANIMAL USE AND CARE RELEVANT TO ANIMAL RESEARCH ETHICS; WHY INVESTIGATORS ARE UNIQUELY QUALIFIED TO ENGAGE IN ETHICAL ASSESSMENT OF ANIMAL RESEARCH; WHY INVESTIGATORS SHOULD COMMIT THEMSELVES TO ETHICAL CONDUCT OF ANIMAL RESEARCH. WHY INVESTIGATORS PLAY THE KEY ROLE IN ASSURING THE ETHICAL CONDUCT OF ANIMAL RESEARCH PROJECTSSOURCES OF SUPPORT AND GUIDANCE IN CONDUCTING ETHICAL RESEARCH; DEVELOPING USEFUL ETHICAL GUIDELINES; FUNDAMENTAL PRINCIPLES OF ANIMAL RESEARCH ETHICS; PRACTICAL ETHICAL GUIDELINES FOR INVESTIGATORS; SOME CURRENT DIFFICULT ISSUES IN ANIMAL RESEARCH ETHICS; GENERAL SUGGESTIONS FOR INVESTIGATORS; References; Chapter 2 -- Access to Resources: A Model Organism Database for Humans; THE PROBLEM; THE LAMHDI SOLUTION; THE IDEAL SOLUTION; Acknowledgments; References. Chapter 3 -- The Advent of the Golden Era of Animal AlternativesINTRODUCTION; ANALYTICAL TOOLS FOR THE DETECTION OF FOOD-BORNE DISEASE; AN IN VITRO SYSTEM TO ASSESS ADVERSE EFFECTS DURING DEVELOPMENT; DISEASES-IN-A-DISH; NONINVASIVE IMAGING AND RECORDING; CONCLUSIONS; References; Chapter 4 -- Environmental Enrichment for Animals Used in Research; INTRODUCTION; APPLIED SCIENCE: ENRICHMENT AS A WELFARE TOOL; BASIC SCIENCE: ENRICHMENT AND ANIMAL MODELS; ENRICHMENT AND EXPERIMENTAL VARIABILITY; ENVIRONMENTAL ENRICHMENT REGULATIONS; IMPLEMENTING AN ENRICHMENT PLAN; CONCLUSIONS; Acknowledgments. RETINAL DEGENERATION CAUSED BY MNU IN VARIOUS ANIMAL SPECIESAGE-RELATED PHOTORECEPTOR CELL DAMAGE AND SENSITIVITY TO MNU; PHOTORECEPTOR CELL DEATH, CELL DEBRIS REMOVAL, AND RPE CELL MIGRATION; MOLECULAR MECHANISMS IN PHOTORECEPTOR CELL DEATH CAUSED BY MNU; THERAPEUTIC TRIALS AGAINST MNU-INDUCED PHOTORECEPTOR APOPTOSIS; CONCLUDING REMARKS; Acknowledgments; References; Part III -CARDIAC AND CARDIOVASCULAR; Chapter 7 -- Animal Models of Myocardial Disease; INTRODUCTION; THE SPECTRUM OF CARDIOVASCULAR DISEASE; CHOICE OF ANIMAL SYSTEM; EXPERIMENTAL DESIGN; ISCHEMIC HEART DISEASE. Diseases Animal models. http://id.loc.gov/authorities/subjects/sh85038412 Laboratory animals. http://id.loc.gov/authorities/subjects/sh85073746 Pathology, Experimental. http://id.loc.gov/authorities/subjects/sh85098689 Disease Models, Animal Animal Experimentation ethics Animal Use Alternatives Animals, Laboratory Maladies Modèles animaux. Animaux de laboratoire. Pathologie expérimentale. MEDICAL Laboratory Medicine. bisacsh Diseases Animal models fast Laboratory animals fast Pathology, Experimental fast Conn, P. Michael, editor. Print version: Animal models for the study of human disease. London ; Waltham, MA : Elsevier, 2013 9780124158948 (DLC) 2013444225 (OCoLC)865180615 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=485976 Volltext CBO01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=485976 Volltext FWS01 ZDB-4-EBA FWS_PDA_EBA https://www.sciencedirect.com/science/book/9780124158948 Volltext CBO01 ZDB-4-EBA FWS_PDA_EBA https://www.sciencedirect.com/science/book/9780124158948 Volltext |
spellingShingle | Animal models for the study of human disease / Front Cover; ANIMAL MODELS FOR THE STUDY OF HUMAN DISEASE; Copyright; Contents; Preface; List of Contributors; Part I -ETHICS, RESOURCES AND APPROACHES; Chapter 1 -- Ethics in Biomedical Animal Research: The Key Role of the Investigator; NATURE AND SCOPE OF THE CHAPTER; THE SUBJECT MATTER OF ANIMAL RESEARCH ETHICS; ASPECTS OF ANIMAL USE AND CARE RELEVANT TO ANIMAL RESEARCH ETHICS; WHY INVESTIGATORS ARE UNIQUELY QUALIFIED TO ENGAGE IN ETHICAL ASSESSMENT OF ANIMAL RESEARCH; WHY INVESTIGATORS SHOULD COMMIT THEMSELVES TO ETHICAL CONDUCT OF ANIMAL RESEARCH. WHY INVESTIGATORS PLAY THE KEY ROLE IN ASSURING THE ETHICAL CONDUCT OF ANIMAL RESEARCH PROJECTSSOURCES OF SUPPORT AND GUIDANCE IN CONDUCTING ETHICAL RESEARCH; DEVELOPING USEFUL ETHICAL GUIDELINES; FUNDAMENTAL PRINCIPLES OF ANIMAL RESEARCH ETHICS; PRACTICAL ETHICAL GUIDELINES FOR INVESTIGATORS; SOME CURRENT DIFFICULT ISSUES IN ANIMAL RESEARCH ETHICS; GENERAL SUGGESTIONS FOR INVESTIGATORS; References; Chapter 2 -- Access to Resources: A Model Organism Database for Humans; THE PROBLEM; THE LAMHDI SOLUTION; THE IDEAL SOLUTION; Acknowledgments; References. Chapter 3 -- The Advent of the Golden Era of Animal AlternativesINTRODUCTION; ANALYTICAL TOOLS FOR THE DETECTION OF FOOD-BORNE DISEASE; AN IN VITRO SYSTEM TO ASSESS ADVERSE EFFECTS DURING DEVELOPMENT; DISEASES-IN-A-DISH; NONINVASIVE IMAGING AND RECORDING; CONCLUSIONS; References; Chapter 4 -- Environmental Enrichment for Animals Used in Research; INTRODUCTION; APPLIED SCIENCE: ENRICHMENT AS A WELFARE TOOL; BASIC SCIENCE: ENRICHMENT AND ANIMAL MODELS; ENRICHMENT AND EXPERIMENTAL VARIABILITY; ENVIRONMENTAL ENRICHMENT REGULATIONS; IMPLEMENTING AN ENRICHMENT PLAN; CONCLUSIONS; Acknowledgments. RETINAL DEGENERATION CAUSED BY MNU IN VARIOUS ANIMAL SPECIESAGE-RELATED PHOTORECEPTOR CELL DAMAGE AND SENSITIVITY TO MNU; PHOTORECEPTOR CELL DEATH, CELL DEBRIS REMOVAL, AND RPE CELL MIGRATION; MOLECULAR MECHANISMS IN PHOTORECEPTOR CELL DEATH CAUSED BY MNU; THERAPEUTIC TRIALS AGAINST MNU-INDUCED PHOTORECEPTOR APOPTOSIS; CONCLUDING REMARKS; Acknowledgments; References; Part III -CARDIAC AND CARDIOVASCULAR; Chapter 7 -- Animal Models of Myocardial Disease; INTRODUCTION; THE SPECTRUM OF CARDIOVASCULAR DISEASE; CHOICE OF ANIMAL SYSTEM; EXPERIMENTAL DESIGN; ISCHEMIC HEART DISEASE. Diseases Animal models. http://id.loc.gov/authorities/subjects/sh85038412 Laboratory animals. http://id.loc.gov/authorities/subjects/sh85073746 Pathology, Experimental. http://id.loc.gov/authorities/subjects/sh85098689 Disease Models, Animal Animal Experimentation ethics Animal Use Alternatives Animals, Laboratory Maladies Modèles animaux. Animaux de laboratoire. Pathologie expérimentale. MEDICAL Laboratory Medicine. bisacsh Diseases Animal models fast Laboratory animals fast Pathology, Experimental fast |
subject_GND | http://id.loc.gov/authorities/subjects/sh85038412 http://id.loc.gov/authorities/subjects/sh85073746 http://id.loc.gov/authorities/subjects/sh85098689 |
title | Animal models for the study of human disease / |
title_auth | Animal models for the study of human disease / |
title_exact_search | Animal models for the study of human disease / |
title_full | Animal models for the study of human disease / edited by P. Michael Conn. |
title_fullStr | Animal models for the study of human disease / edited by P. Michael Conn. |
title_full_unstemmed | Animal models for the study of human disease / edited by P. Michael Conn. |
title_short | Animal models for the study of human disease / |
title_sort | animal models for the study of human disease |
topic | Diseases Animal models. http://id.loc.gov/authorities/subjects/sh85038412 Laboratory animals. http://id.loc.gov/authorities/subjects/sh85073746 Pathology, Experimental. http://id.loc.gov/authorities/subjects/sh85098689 Disease Models, Animal Animal Experimentation ethics Animal Use Alternatives Animals, Laboratory Maladies Modèles animaux. Animaux de laboratoire. Pathologie expérimentale. MEDICAL Laboratory Medicine. bisacsh Diseases Animal models fast Laboratory animals fast Pathology, Experimental fast |
topic_facet | Diseases Animal models. Laboratory animals. Pathology, Experimental. Disease Models, Animal Animal Experimentation ethics Animal Use Alternatives Animals, Laboratory Maladies Modèles animaux. Animaux de laboratoire. Pathologie expérimentale. MEDICAL Laboratory Medicine. Diseases Animal models Laboratory animals Pathology, Experimental |
url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=485976 https://www.sciencedirect.com/science/book/9780124158948 |
work_keys_str_mv | AT connpmichael animalmodelsforthestudyofhumandisease |