Kallikrein-related peptidases.: Volume 1, Characterization, regulation, and interactions within the protease web /
The KLK proteins and their encoding genes are increasingly attracting attention among scientists and clinicians worldwide as they represent interesting and functionally distinct biomarkers both under physiological and pathophysiological conditions. This volume on kallikrein-related peptidases (KLKs)...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Berlin :
Walter de Gruyter,
©2012.
|
| Schriftenreihe: | Kallikrein-related peptidases ;
Volume 1 |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | The KLK proteins and their encoding genes are increasingly attracting attention among scientists and clinicians worldwide as they represent interesting and functionally distinct biomarkers both under physiological and pathophysiological conditions. This volume on kallikrein-related peptidases (KLKs) reviews the characterization, regulation, and interactions of these proteases within the protease web. |
| Beschreibung: | 1 online resource (xvii, 409 pages) : illustrations |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9783110260373 3110260379 |
Internformat
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| 245 | 0 | 0 | |a Kallikrein-related peptidases. |n Volume 1, |p Characterization, regulation, and interactions within the protease web / |c Viktor Magdolen [and others], editors. |
| 260 | |a Berlin : |b Walter de Gruyter, |c ©2012. | ||
| 300 | |a 1 online resource (xvii, 409 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 0 | |a Kallikrein-related peptidases ; |v Volume 1 | |
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Genomic structure of the KLK locus -- Single nucleotide polymorphisms in the human KLK locus and their implication in various diseases -- Evolution of Kallikrein-related peptidases -- Structural aspects of Kallikrein-related peptidases -- Molecular recognition properties of Kallikrein-related peptidases on synthetic and endogenous substrates -- Natural, engineered, and synthetic inhibitors of Kallikrein-related peptidases -- Kallikrein-related peptidases as pharmaceutical targets -- Expression of Kallikrein-related peptidases under (patho) physiological conditions -- Kallikrein-related peptidases within the proteolytic web -- Kallikrein-Kinin cascade: bioregulation by human tissue kallikrein 1 (HK1, KLK 1) -- Role of KLK4 in dental enamel formation. | |
| 505 | 0 | |a Kallikrein-related peptidases and semen -- Kallikrein-related peptidases and inhibitors of the skin -- Physiological and pathophysiological roles of Kallikrein-related peptidases in the central nervous system -- Kallikrein-related peptidases (KLKS), proteinase-mediated signaling and proteinase-activated receptors (PARS) -- Pathophysiology of Kallikrein-related peptidases in lung cancer -- Clinical relevance of Kallikrein-related peptidases in gastric and colorectal cancer -- Pathophysiology of Kallikrein-related peptidases in head and neck cancer -- PSA (prostate-specific antigen) and other Kallikrein-related peptidases in prostate cancer -- Cellular model systems to study the tumor biological role of Kallikrein-related peptidases in ovarian and prostate cancer -- Clinical relevance of Kallikrein-related peptidases in breast cancer -- Clinical relevance of Kallikrein-related peptidases in ovarian cancer -- MicroRNAs : a new control mechanism for Kallikrein-related peptidases in kidney and other cancers -- Genomic instability of the KLK-locus in cancer -- Kallikrein-related peptidases as biomarkers in personalized cancer medicine. | |
| 520 | |a The KLK proteins and their encoding genes are increasingly attracting attention among scientists and clinicians worldwide as they represent interesting and functionally distinct biomarkers both under physiological and pathophysiological conditions. This volume on kallikrein-related peptidases (KLKs) reviews the characterization, regulation, and interactions of these proteases within the protease web. | ||
| 546 | |a English. | ||
| 650 | 0 | |a Kallikrein |x Genetics. | |
| 650 | 0 | |a Kallikrein |x Metabolism. | |
| 650 | 0 | |a Tumors |x Genetics. | |
| 650 | 0 | |a Proteolytic enzymes |x Metabolism. | |
| 650 | 6 | |a Kallicréine |x Génétique. | |
| 650 | 6 | |a Kallicréine |x Métabolisme. | |
| 650 | 6 | |a Tumeurs |x Génétique. | |
| 650 | 6 | |a Enzymes protéolytiques |x Métabolisme. | |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x Cancer. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Oncology. |2 bisacsh | |
| 700 | 1 | |a Magdolen, Viktor. | |
| 758 | |i has work: |a 1 Characterization, regulation, and interactions within the protease web Kallikrein-related peptidases (Work) |1 https://id.oclc.org/worldcat/entity/E39PCGh3KRhQmhdXj8PKYR8YGd |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Schmitt, Manfred. |t Kallikrein-related peptidases : Characterization, Regulation, and Interactions Within the Protease Web. |d Berlin : De Gruyter, ©2012 |z 9783110260366 |
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| contents | Genomic structure of the KLK locus -- Single nucleotide polymorphisms in the human KLK locus and their implication in various diseases -- Evolution of Kallikrein-related peptidases -- Structural aspects of Kallikrein-related peptidases -- Molecular recognition properties of Kallikrein-related peptidases on synthetic and endogenous substrates -- Natural, engineered, and synthetic inhibitors of Kallikrein-related peptidases -- Kallikrein-related peptidases as pharmaceutical targets -- Expression of Kallikrein-related peptidases under (patho) physiological conditions -- Kallikrein-related peptidases within the proteolytic web -- Kallikrein-Kinin cascade: bioregulation by human tissue kallikrein 1 (HK1, KLK 1) -- Role of KLK4 in dental enamel formation. Kallikrein-related peptidases and semen -- Kallikrein-related peptidases and inhibitors of the skin -- Physiological and pathophysiological roles of Kallikrein-related peptidases in the central nervous system -- Kallikrein-related peptidases (KLKS), proteinase-mediated signaling and proteinase-activated receptors (PARS) -- Pathophysiology of Kallikrein-related peptidases in lung cancer -- Clinical relevance of Kallikrein-related peptidases in gastric and colorectal cancer -- Pathophysiology of Kallikrein-related peptidases in head and neck cancer -- PSA (prostate-specific antigen) and other Kallikrein-related peptidases in prostate cancer -- Cellular model systems to study the tumor biological role of Kallikrein-related peptidases in ovarian and prostate cancer -- Clinical relevance of Kallikrein-related peptidases in breast cancer -- Clinical relevance of Kallikrein-related peptidases in ovarian cancer -- MicroRNAs : a new control mechanism for Kallikrein-related peptidases in kidney and other cancers -- Genomic instability of the KLK-locus in cancer -- Kallikrein-related peptidases as biomarkers in personalized cancer medicine. |
| ctrlnum | (OCoLC)828736053 |
| dewey-full | 616.99/4042 |
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| dewey-ones | 616 - Diseases |
| dewey-raw | 616.99/4042 |
| dewey-search | 616.99/4042 |
| dewey-sort | 3616.99 44042 |
| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Medizin |
| format | Electronic eBook |
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| id | ZDB-4-EBA-ocn828736053 |
| illustrated | Illustrated |
| indexdate | 2024-11-27T13:25:12Z |
| institution | BVB |
| isbn | 9783110260373 3110260379 |
| language | English |
| oclc_num | 828736053 |
| open_access_boolean | |
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| physical | 1 online resource (xvii, 409 pages) : illustrations |
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| publishDateSearch | 2012 |
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| publisher | Walter de Gruyter, |
| record_format | marc |
| series2 | Kallikrein-related peptidases ; |
| spelling | Kallikrein-related peptidases. Volume 1, Characterization, regulation, and interactions within the protease web / Viktor Magdolen [and others], editors. Berlin : Walter de Gruyter, ©2012. 1 online resource (xvii, 409 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier Kallikrein-related peptidases ; Volume 1 Includes bibliographical references and index. Genomic structure of the KLK locus -- Single nucleotide polymorphisms in the human KLK locus and their implication in various diseases -- Evolution of Kallikrein-related peptidases -- Structural aspects of Kallikrein-related peptidases -- Molecular recognition properties of Kallikrein-related peptidases on synthetic and endogenous substrates -- Natural, engineered, and synthetic inhibitors of Kallikrein-related peptidases -- Kallikrein-related peptidases as pharmaceutical targets -- Expression of Kallikrein-related peptidases under (patho) physiological conditions -- Kallikrein-related peptidases within the proteolytic web -- Kallikrein-Kinin cascade: bioregulation by human tissue kallikrein 1 (HK1, KLK 1) -- Role of KLK4 in dental enamel formation. Kallikrein-related peptidases and semen -- Kallikrein-related peptidases and inhibitors of the skin -- Physiological and pathophysiological roles of Kallikrein-related peptidases in the central nervous system -- Kallikrein-related peptidases (KLKS), proteinase-mediated signaling and proteinase-activated receptors (PARS) -- Pathophysiology of Kallikrein-related peptidases in lung cancer -- Clinical relevance of Kallikrein-related peptidases in gastric and colorectal cancer -- Pathophysiology of Kallikrein-related peptidases in head and neck cancer -- PSA (prostate-specific antigen) and other Kallikrein-related peptidases in prostate cancer -- Cellular model systems to study the tumor biological role of Kallikrein-related peptidases in ovarian and prostate cancer -- Clinical relevance of Kallikrein-related peptidases in breast cancer -- Clinical relevance of Kallikrein-related peptidases in ovarian cancer -- MicroRNAs : a new control mechanism for Kallikrein-related peptidases in kidney and other cancers -- Genomic instability of the KLK-locus in cancer -- Kallikrein-related peptidases as biomarkers in personalized cancer medicine. The KLK proteins and their encoding genes are increasingly attracting attention among scientists and clinicians worldwide as they represent interesting and functionally distinct biomarkers both under physiological and pathophysiological conditions. This volume on kallikrein-related peptidases (KLKs) reviews the characterization, regulation, and interactions of these proteases within the protease web. English. Kallikrein Genetics. Kallikrein Metabolism. Tumors Genetics. Proteolytic enzymes Metabolism. Kallicréine Génétique. Kallicréine Métabolisme. Tumeurs Génétique. Enzymes protéolytiques Métabolisme. HEALTH & FITNESS Diseases Cancer. bisacsh MEDICAL Oncology. bisacsh Magdolen, Viktor. has work: 1 Characterization, regulation, and interactions within the protease web Kallikrein-related peptidases (Work) https://id.oclc.org/worldcat/entity/E39PCGh3KRhQmhdXj8PKYR8YGd https://id.oclc.org/worldcat/ontology/hasWork Print version: Schmitt, Manfred. Kallikrein-related peptidases : Characterization, Regulation, and Interactions Within the Protease Web. Berlin : De Gruyter, ©2012 9783110260366 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=530541 Volltext |
| spellingShingle | Kallikrein-related peptidases. Genomic structure of the KLK locus -- Single nucleotide polymorphisms in the human KLK locus and their implication in various diseases -- Evolution of Kallikrein-related peptidases -- Structural aspects of Kallikrein-related peptidases -- Molecular recognition properties of Kallikrein-related peptidases on synthetic and endogenous substrates -- Natural, engineered, and synthetic inhibitors of Kallikrein-related peptidases -- Kallikrein-related peptidases as pharmaceutical targets -- Expression of Kallikrein-related peptidases under (patho) physiological conditions -- Kallikrein-related peptidases within the proteolytic web -- Kallikrein-Kinin cascade: bioregulation by human tissue kallikrein 1 (HK1, KLK 1) -- Role of KLK4 in dental enamel formation. Kallikrein-related peptidases and semen -- Kallikrein-related peptidases and inhibitors of the skin -- Physiological and pathophysiological roles of Kallikrein-related peptidases in the central nervous system -- Kallikrein-related peptidases (KLKS), proteinase-mediated signaling and proteinase-activated receptors (PARS) -- Pathophysiology of Kallikrein-related peptidases in lung cancer -- Clinical relevance of Kallikrein-related peptidases in gastric and colorectal cancer -- Pathophysiology of Kallikrein-related peptidases in head and neck cancer -- PSA (prostate-specific antigen) and other Kallikrein-related peptidases in prostate cancer -- Cellular model systems to study the tumor biological role of Kallikrein-related peptidases in ovarian and prostate cancer -- Clinical relevance of Kallikrein-related peptidases in breast cancer -- Clinical relevance of Kallikrein-related peptidases in ovarian cancer -- MicroRNAs : a new control mechanism for Kallikrein-related peptidases in kidney and other cancers -- Genomic instability of the KLK-locus in cancer -- Kallikrein-related peptidases as biomarkers in personalized cancer medicine. Kallikrein Genetics. Kallikrein Metabolism. Tumors Genetics. Proteolytic enzymes Metabolism. Kallicréine Génétique. Kallicréine Métabolisme. Tumeurs Génétique. Enzymes protéolytiques Métabolisme. HEALTH & FITNESS Diseases Cancer. bisacsh MEDICAL Oncology. bisacsh |
| title | Kallikrein-related peptidases. |
| title_auth | Kallikrein-related peptidases. |
| title_exact_search | Kallikrein-related peptidases. |
| title_full | Kallikrein-related peptidases. Volume 1, Characterization, regulation, and interactions within the protease web / Viktor Magdolen [and others], editors. |
| title_fullStr | Kallikrein-related peptidases. Volume 1, Characterization, regulation, and interactions within the protease web / Viktor Magdolen [and others], editors. |
| title_full_unstemmed | Kallikrein-related peptidases. Volume 1, Characterization, regulation, and interactions within the protease web / Viktor Magdolen [and others], editors. |
| title_short | Kallikrein-related peptidases. |
| title_sort | kallikrein related peptidases characterization regulation and interactions within the protease web |
| topic | Kallikrein Genetics. Kallikrein Metabolism. Tumors Genetics. Proteolytic enzymes Metabolism. Kallicréine Génétique. Kallicréine Métabolisme. Tumeurs Génétique. Enzymes protéolytiques Métabolisme. HEALTH & FITNESS Diseases Cancer. bisacsh MEDICAL Oncology. bisacsh |
| topic_facet | Kallikrein Genetics. Kallikrein Metabolism. Tumors Genetics. Proteolytic enzymes Metabolism. Kallicréine Génétique. Kallicréine Métabolisme. Tumeurs Génétique. Enzymes protéolytiques Métabolisme. HEALTH & FITNESS Diseases Cancer. MEDICAL Oncology. |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=530541 |
| work_keys_str_mv | AT magdolenviktor kallikreinrelatedpeptidasesvolume1 |