Gene targeting :: a practical approach /
"This new edition of Gene Targeting: A Practical Approach contains a remarkable collection of state-of-the-art protocols as well as thoughtful discussion of how to design a new mouse mutation and analyse the resulting phenotype to maximise the information gained. The techniques described for ge...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Oxford ; New York :
Oxford University Press,
2000.
|
| Ausgabe: | 2nd ed. |
| Schriftenreihe: | Practical approach series.
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | "This new edition of Gene Targeting: A Practical Approach contains a remarkable collection of state-of-the-art protocols as well as thoughtful discussion of how to design a new mouse mutation and analyse the resulting phenotype to maximise the information gained. The techniques described for gene targeting in mouse ES cells, are equally applicable for gene targeting in other tissue culture cells, including human cells. The second edition describes additional genetic approaches for studying gene function in mice, including chimera analysis, gene trap (GT) approaches and powerful ways to combine gene targeting with classical genetics." "Gene Targeting: A Practical Approach (second edition) is a practical tool and information resource for scientists working on fundamental or applied aspects of gene targeting, ES cell manipulation, and analysis of mouse mutants. It will be invaluable to all researchers who wish to use the approaches for studies of gene function in cells or mice."--Provided by publisher. |
| Beschreibung: | 1 online resource (xviii, 293 pages) : illustrations. |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9780585483955 0585483957 |
Internformat
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| contents | Gene targeting, principles, and practice in mammalian cells / Paul Hasty, Alejandro Abuin, and Allan Bradley -- Site-specific recombination in cells and mice / Susan M. Dymecki -- Production of targeted embryonic stem cell clones / Michael P. Matise, Wojtek Auerbach and Alexandra L. Joyner -- Production of chimeras by blastocyst and morula injection of targeted ES cells / Virginia Papaioannou and Randall Johnson -- Production and analysis of ES cell aggregation chimeras / Andreas Nagy and Janet Rossant -- Gene trap strategies in ES cells / Wolfgang Wurst and Achim Gossler -- Classical genetics and gene targeting / Scott Bultman and Terry Magnuson. |
| ctrlnum | (OCoLC)666954936 |
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| dewey-raw | 660.6/5 |
| dewey-search | 660.6/5 |
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| discipline | Chemie / Pharmazie Biologie |
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| genre | Laboratory Manual Laboratory manuals fast Laboratory manuals. lcgft http://id.loc.gov/authorities/genreForms/gf2014026120 Manuels de laboratoire. rvmgf |
| genre_facet | Laboratory Manual Laboratory manuals Laboratory manuals. Manuels de laboratoire. |
| id | ZDB-4-EBA-ocn666954936 |
| illustrated | Illustrated |
| indexdate | 2024-11-27T13:17:31Z |
| institution | BVB |
| isbn | 9780585483955 0585483957 |
| language | English |
| oclc_num | 666954936 |
| open_access_boolean | |
| owner | MAIN DE-863 DE-BY-FWS |
| owner_facet | MAIN DE-863 DE-BY-FWS |
| physical | 1 online resource (xviii, 293 pages) : illustrations. |
| psigel | ZDB-4-EBA |
| publishDate | 2000 |
| publishDateSearch | 2000 |
| publishDateSort | 2000 |
| publisher | Oxford University Press, |
| record_format | marc |
| series | Practical approach series. |
| series2 | Practical approach series |
| spelling | Gene targeting : a practical approach / edited by Alexandra L. Joyner. 2nd ed. Oxford ; New York : Oxford University Press, 2000. 1 online resource (xviii, 293 pages) : illustrations. text txt rdacontent computer c rdamedia online resource cr rdacarrier Practical approach series Includes bibliographical references and index. Print version record. "This new edition of Gene Targeting: A Practical Approach contains a remarkable collection of state-of-the-art protocols as well as thoughtful discussion of how to design a new mouse mutation and analyse the resulting phenotype to maximise the information gained. The techniques described for gene targeting in mouse ES cells, are equally applicable for gene targeting in other tissue culture cells, including human cells. The second edition describes additional genetic approaches for studying gene function in mice, including chimera analysis, gene trap (GT) approaches and powerful ways to combine gene targeting with classical genetics." "Gene Targeting: A Practical Approach (second edition) is a practical tool and information resource for scientists working on fundamental or applied aspects of gene targeting, ES cell manipulation, and analysis of mouse mutants. It will be invaluable to all researchers who wish to use the approaches for studies of gene function in cells or mice."--Provided by publisher. Gene targeting, principles, and practice in mammalian cells / Paul Hasty, Alejandro Abuin, and Allan Bradley -- Site-specific recombination in cells and mice / Susan M. Dymecki -- Production of targeted embryonic stem cell clones / Michael P. Matise, Wojtek Auerbach and Alexandra L. Joyner -- Production of chimeras by blastocyst and morula injection of targeted ES cells / Virginia Papaioannou and Randall Johnson -- Production and analysis of ES cell aggregation chimeras / Andreas Nagy and Janet Rossant -- Gene trap strategies in ES cells / Wolfgang Wurst and Achim Gossler -- Classical genetics and gene targeting / Scott Bultman and Terry Magnuson. Gene targeting Laboratory manuals. Gene targeting. http://id.loc.gov/authorities/subjects/sh97003192 Gene Targeting Gènes Ciblage Manuels de laboratoire. Gènes Ciblage. SCIENCE Biotechnology. bisacsh Gene targeting fast Ciblage gène. fmesh Blutstammzelle gnd http://d-nb.info/gnd/4146093-5 Gen-Targeting gnd http://d-nb.info/gnd/4294998-1 Gentechnologie gnd Methode gnd Maus gnd http://d-nb.info/gnd/4169148-9 Genetische manipulatie. gtt Methoden. gtt Ciblage d'un gène Manuels de laboratoire. ram Laboratory Manual Laboratory manuals fast Laboratory manuals. lcgft http://id.loc.gov/authorities/genreForms/gf2014026120 Manuels de laboratoire. rvmgf Joyner, Alexandra L., editor. Print version: Gene targeting. 2nd ed. Oxford ; New York : Oxford University Press, 2000 9780199637935 9780199637928 (DLC) 99036660 (OCoLC)41649667 Practical approach series. http://id.loc.gov/authorities/names/n84709852 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=98477 Volltext |
| spellingShingle | Gene targeting : a practical approach / Practical approach series. Gene targeting, principles, and practice in mammalian cells / Paul Hasty, Alejandro Abuin, and Allan Bradley -- Site-specific recombination in cells and mice / Susan M. Dymecki -- Production of targeted embryonic stem cell clones / Michael P. Matise, Wojtek Auerbach and Alexandra L. Joyner -- Production of chimeras by blastocyst and morula injection of targeted ES cells / Virginia Papaioannou and Randall Johnson -- Production and analysis of ES cell aggregation chimeras / Andreas Nagy and Janet Rossant -- Gene trap strategies in ES cells / Wolfgang Wurst and Achim Gossler -- Classical genetics and gene targeting / Scott Bultman and Terry Magnuson. Gene targeting Laboratory manuals. Gene targeting. http://id.loc.gov/authorities/subjects/sh97003192 Gene Targeting Gènes Ciblage Manuels de laboratoire. Gènes Ciblage. SCIENCE Biotechnology. bisacsh Gene targeting fast Ciblage gène. fmesh Blutstammzelle gnd http://d-nb.info/gnd/4146093-5 Gen-Targeting gnd http://d-nb.info/gnd/4294998-1 Gentechnologie gnd Methode gnd Maus gnd http://d-nb.info/gnd/4169148-9 Genetische manipulatie. gtt Methoden. gtt Ciblage d'un gène Manuels de laboratoire. ram |
| subject_GND | http://id.loc.gov/authorities/subjects/sh97003192 http://d-nb.info/gnd/4146093-5 http://d-nb.info/gnd/4294998-1 http://d-nb.info/gnd/4169148-9 http://id.loc.gov/authorities/genreForms/gf2014026120 |
| title | Gene targeting : a practical approach / |
| title_auth | Gene targeting : a practical approach / |
| title_exact_search | Gene targeting : a practical approach / |
| title_full | Gene targeting : a practical approach / edited by Alexandra L. Joyner. |
| title_fullStr | Gene targeting : a practical approach / edited by Alexandra L. Joyner. |
| title_full_unstemmed | Gene targeting : a practical approach / edited by Alexandra L. Joyner. |
| title_short | Gene targeting : |
| title_sort | gene targeting a practical approach |
| title_sub | a practical approach / |
| topic | Gene targeting Laboratory manuals. Gene targeting. http://id.loc.gov/authorities/subjects/sh97003192 Gene Targeting Gènes Ciblage Manuels de laboratoire. Gènes Ciblage. SCIENCE Biotechnology. bisacsh Gene targeting fast Ciblage gène. fmesh Blutstammzelle gnd http://d-nb.info/gnd/4146093-5 Gen-Targeting gnd http://d-nb.info/gnd/4294998-1 Gentechnologie gnd Methode gnd Maus gnd http://d-nb.info/gnd/4169148-9 Genetische manipulatie. gtt Methoden. gtt Ciblage d'un gène Manuels de laboratoire. ram |
| topic_facet | Gene targeting Laboratory manuals. Gene targeting. Gene Targeting Gènes Ciblage Manuels de laboratoire. Gènes Ciblage. SCIENCE Biotechnology. Gene targeting Ciblage gène. Blutstammzelle Gen-Targeting Gentechnologie Methode Maus Genetische manipulatie. Methoden. Ciblage d'un gène Manuels de laboratoire. Laboratory Manual Laboratory manuals Laboratory manuals. Manuels de laboratoire. |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=98477 |
| work_keys_str_mv | AT joyneralexandral genetargetingapracticalapproach |