Genomics and clinical medicine /:
An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30,000 genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease. This advance has also laid the foundation for a broad range of geno...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Oxford ; New York :
Oxford University Press,
2008.
|
| Schriftenreihe: | Oxford monographs on medical genetics ;
no. 53. |
| Schlagworte: | |
| Online-Zugang: | DE-862 DE-863 |
| Zusammenfassung: | An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30,000 genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease. This advance has also laid the foundation for a broad range of genomic tools that have opened the way for targeted genetic testing in a number of medical disorders. This book is designed to be the first major text to discuss genomics-based advances in disease susceptibility, diagnosis, prognostication,and prediction of treatment outcomes in various areas of medicine. After building a strong underpinning in the basic concepts of genomics, the authors of this book, all leaders in the field, proceed to discuss a wide range of clinical areas and the applications now afforded by genomic analysis. |
| Beschreibung: | 1 online resource (xix, 651 pages) : illustrations (some color), maps (chiefly color). |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9780199720057 0199720053 |
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| 245 | 0 | 0 | |a Genomics and clinical medicine / |c edited by Dhavendra Kumar ; advisory editor, Sir David Weatherall. |
| 260 | |a Oxford ; |a New York : |b Oxford University Press, |c 2008. | ||
| 300 | |a 1 online resource (xix, 651 pages) : |b illustrations (some color), maps (chiefly color). | ||
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| 490 | 1 | |a Oxford monographs on medical genetics ; |v 53 | |
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Part I. General genomics. From genes to genomes: a historical perspective / Ian Dunham and Don Powell -- The human genome: structure and organization / Andrew Read -- Human functional genomics and proteomics / Yoshiji Yamada, Sahoko Ichiahara, and Masaharu Takemura -- Epigenomics and human disease / Santiago Uribe Lewis, Christopher Everett, and Richard Festenstein -- Genomic perspective of human development / Dhavendra Kumar -- Genetic and genomic approaches to taxonomy of human disease / Dhavendra Kumar -- Genomic technologies / Ian M. Frayling -- Nutritional genomics / Patrick J. Stover -- Pharmacogenomics: drug development, drug response, and precision medicines / Michelle Penny and Duncan McHale -- Part II. Clinical genomics. Clinical medicine in the genome era: an introduction / Dhavendra Kumar -- Complex cardiovascular disorders / Dan E. Arking -- Diabetes mellitus and obesity / Mark I. McCarthy -- Chronic renal disease / Albert C.M. Ong and A. Peter Maxwell -- Hemostasis and thrombosis / John H. McVet and Edward G.D. Tuddenham -- Disorders of platelets / Wadie F. Bahou -- Applications in critical care medicine / Christopher S. Garrard, Charles Hinds, and Julian Knight -- The epilepsies / Mark Gardiner -- Neurodegenerative disorders: tauopathies and synucleinopathies / Huw R. Morris and Andrew Singleton -- Neuropsychiatric disease I: schizophrenia / Patrick F. Sullivan -- Neuropsychiatric diseases II: mood disorders / Dhavendra Kumar -- Asthma and chronic obstructive pulmonary disease / William O.C. Cookson -- Inflammatory bowel disease / Saad Pathan and Derek Jewell -- Genomics and cancer: mechanisms and applications / Mark Davies and Julian Sampson -- Hematological malignancies: the paradigm of acute myeloid leukemia / Kenneth I. Mills and Alan Burnett -- Genomics and infectious diseases: susceptibility, resistance, antimicrobial therapy / Sarra E. Jamiesson and Christopher S. Peacock. | |
| 505 | 0 | |a Rheumatoid arthritis and related arthropathies / Pille Harrison and Paul Wordsworth -- Immunological disorders / Tineke C.M.T. van der Pouw Kraan and Cornelis L. Verweij -- Applications in clinical pediatrics / Michael R. Konikoff and Michael D. Bates -- Learning and behavioral disorders / Lucy Raymound and James Cox -- Complex ophthalmic disorders / Forbes D.C. Manson, Andrew R. Webster, and Graeme C.M. Black -- Application in audiological medicine / Lut van Laer and Guy van Camp -- Complex skin diseases I: psoriasis / Colin Veal and David Burden -- Complex skin diseases II: atopic dermatitis / Nilesh Morar -- Diseases of the epidermis and appendages, skin pigmentation and skin cancer / Eugene Healy [and others] -- Osteoporosis and related disorders / Yoshiji Yamada -- Applications in obstetrics and gynecology and reproductive medicine / Gareth C. Weston, Anna Ponnampalam, and Peter A.W. Rogers -- Stem cell genomics, and regenerative medicine / Philip Gaughwin, Wai-Leong Tam, and Bing Lim -- Part III. Health genomics. Genomics and global health / Sir David Weatherall and Dhavendra Kumar -- Genetic testing and genomic screening / Angus Clarke -- Ethical, legal, and social issues (ELSI) / Michael Parker -- The regulation of human genomics research / Jane Kaye. | |
| 588 | 0 | |a Print version record. | |
| 520 | |a An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30,000 genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease. This advance has also laid the foundation for a broad range of genomic tools that have opened the way for targeted genetic testing in a number of medical disorders. This book is designed to be the first major text to discuss genomics-based advances in disease susceptibility, diagnosis, prognostication,and prediction of treatment outcomes in various areas of medicine. After building a strong underpinning in the basic concepts of genomics, the authors of this book, all leaders in the field, proceed to discuss a wide range of clinical areas and the applications now afforded by genomic analysis. | ||
| 650 | 0 | |a Medical genetics. |0 http://id.loc.gov/authorities/subjects/sh85082937 | |
| 650 | 0 | |a Genomics. |0 http://id.loc.gov/authorities/subjects/sh2002000809 | |
| 650 | 0 | |a Clinical medicine. |0 http://id.loc.gov/authorities/subjects/sh85083129 | |
| 650 | 0 | |a Pharmacogenetics. |0 http://id.loc.gov/authorities/subjects/sh85100595 | |
| 650 | 2 | 2 | |a Clinical Medicine |
| 650 | 2 | 2 | |a Genetic Predisposition to Disease |
| 650 | 2 | 2 | |a Pharmacogenetics |
| 650 | 2 | |a Genetics, Medical |0 https://id.nlm.nih.gov/mesh/D005826 | |
| 650 | 2 | |a Genomics |0 https://id.nlm.nih.gov/mesh/D023281 | |
| 650 | 6 | |a Génétique médicale. | |
| 650 | 6 | |a Génomique. | |
| 650 | 6 | |a Médecine clinique. | |
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| 650 | 7 | |a Medical genetics |2 fast | |
| 655 | 0 | |a Electronic books. | |
| 700 | 1 | |a Kumar, Dhavendra. | |
| 700 | 1 | |a Weatherall, D. J. | |
| 776 | 0 | 8 | |i Print version: |t Genomics and clinical medicine. |d Oxford ; New York : Oxford University Press, 2008 |z 9780195188134 |w (DLC) 2006034212 |w (OCoLC)73927254 |
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| contents | Part I. General genomics. From genes to genomes: a historical perspective / Ian Dunham and Don Powell -- The human genome: structure and organization / Andrew Read -- Human functional genomics and proteomics / Yoshiji Yamada, Sahoko Ichiahara, and Masaharu Takemura -- Epigenomics and human disease / Santiago Uribe Lewis, Christopher Everett, and Richard Festenstein -- Genomic perspective of human development / Dhavendra Kumar -- Genetic and genomic approaches to taxonomy of human disease / Dhavendra Kumar -- Genomic technologies / Ian M. Frayling -- Nutritional genomics / Patrick J. Stover -- Pharmacogenomics: drug development, drug response, and precision medicines / Michelle Penny and Duncan McHale -- Part II. Clinical genomics. Clinical medicine in the genome era: an introduction / Dhavendra Kumar -- Complex cardiovascular disorders / Dan E. Arking -- Diabetes mellitus and obesity / Mark I. McCarthy -- Chronic renal disease / Albert C.M. Ong and A. Peter Maxwell -- Hemostasis and thrombosis / John H. McVet and Edward G.D. Tuddenham -- Disorders of platelets / Wadie F. Bahou -- Applications in critical care medicine / Christopher S. Garrard, Charles Hinds, and Julian Knight -- The epilepsies / Mark Gardiner -- Neurodegenerative disorders: tauopathies and synucleinopathies / Huw R. Morris and Andrew Singleton -- Neuropsychiatric disease I: schizophrenia / Patrick F. Sullivan -- Neuropsychiatric diseases II: mood disorders / Dhavendra Kumar -- Asthma and chronic obstructive pulmonary disease / William O.C. Cookson -- Inflammatory bowel disease / Saad Pathan and Derek Jewell -- Genomics and cancer: mechanisms and applications / Mark Davies and Julian Sampson -- Hematological malignancies: the paradigm of acute myeloid leukemia / Kenneth I. Mills and Alan Burnett -- Genomics and infectious diseases: susceptibility, resistance, antimicrobial therapy / Sarra E. Jamiesson and Christopher S. Peacock. Rheumatoid arthritis and related arthropathies / Pille Harrison and Paul Wordsworth -- Immunological disorders / Tineke C.M.T. van der Pouw Kraan and Cornelis L. Verweij -- Applications in clinical pediatrics / Michael R. Konikoff and Michael D. Bates -- Learning and behavioral disorders / Lucy Raymound and James Cox -- Complex ophthalmic disorders / Forbes D.C. Manson, Andrew R. Webster, and Graeme C.M. Black -- Application in audiological medicine / Lut van Laer and Guy van Camp -- Complex skin diseases I: psoriasis / Colin Veal and David Burden -- Complex skin diseases II: atopic dermatitis / Nilesh Morar -- Diseases of the epidermis and appendages, skin pigmentation and skin cancer / Eugene Healy [and others] -- Osteoporosis and related disorders / Yoshiji Yamada -- Applications in obstetrics and gynecology and reproductive medicine / Gareth C. Weston, Anna Ponnampalam, and Peter A.W. Rogers -- Stem cell genomics, and regenerative medicine / Philip Gaughwin, Wai-Leong Tam, and Bing Lim -- Part III. Health genomics. Genomics and global health / Sir David Weatherall and Dhavendra Kumar -- Genetic testing and genomic screening / Angus Clarke -- Ethical, legal, and social issues (ELSI) / Michael Parker -- The regulation of human genomics research / Jane Kaye. |
| ctrlnum | (OCoLC)607554819 |
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| dewey-ones | 616 - Diseases |
| dewey-raw | 616/.042 |
| dewey-search | 616/.042 |
| dewey-sort | 3616 242 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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| genre | Electronic books. |
| genre_facet | Electronic books. |
| id | ZDB-4-EBA-ocn607554819 |
| illustrated | Illustrated |
| indexdate | 2025-04-11T08:36:39Z |
| institution | BVB |
| isbn | 9780199720057 0199720053 |
| language | English |
| oclc_num | 607554819 |
| open_access_boolean | |
| owner | MAIN DE-862 DE-BY-FWS DE-863 DE-BY-FWS |
| owner_facet | MAIN DE-862 DE-BY-FWS DE-863 DE-BY-FWS |
| physical | 1 online resource (xix, 651 pages) : illustrations (some color), maps (chiefly color). |
| psigel | ZDB-4-EBA FWS_PDA_EBA ZDB-4-EBA |
| publishDate | 2008 |
| publishDateSearch | 2008 |
| publishDateSort | 2008 |
| publisher | Oxford University Press, |
| record_format | marc |
| series | Oxford monographs on medical genetics ; |
| series2 | Oxford monographs on medical genetics ; |
| spelling | Genomics and clinical medicine / edited by Dhavendra Kumar ; advisory editor, Sir David Weatherall. Oxford ; New York : Oxford University Press, 2008. 1 online resource (xix, 651 pages) : illustrations (some color), maps (chiefly color). text txt rdacontent computer c rdamedia online resource cr rdacarrier Oxford monographs on medical genetics ; 53 Includes bibliographical references and index. Part I. General genomics. From genes to genomes: a historical perspective / Ian Dunham and Don Powell -- The human genome: structure and organization / Andrew Read -- Human functional genomics and proteomics / Yoshiji Yamada, Sahoko Ichiahara, and Masaharu Takemura -- Epigenomics and human disease / Santiago Uribe Lewis, Christopher Everett, and Richard Festenstein -- Genomic perspective of human development / Dhavendra Kumar -- Genetic and genomic approaches to taxonomy of human disease / Dhavendra Kumar -- Genomic technologies / Ian M. Frayling -- Nutritional genomics / Patrick J. Stover -- Pharmacogenomics: drug development, drug response, and precision medicines / Michelle Penny and Duncan McHale -- Part II. Clinical genomics. Clinical medicine in the genome era: an introduction / Dhavendra Kumar -- Complex cardiovascular disorders / Dan E. Arking -- Diabetes mellitus and obesity / Mark I. McCarthy -- Chronic renal disease / Albert C.M. Ong and A. Peter Maxwell -- Hemostasis and thrombosis / John H. McVet and Edward G.D. Tuddenham -- Disorders of platelets / Wadie F. Bahou -- Applications in critical care medicine / Christopher S. Garrard, Charles Hinds, and Julian Knight -- The epilepsies / Mark Gardiner -- Neurodegenerative disorders: tauopathies and synucleinopathies / Huw R. Morris and Andrew Singleton -- Neuropsychiatric disease I: schizophrenia / Patrick F. Sullivan -- Neuropsychiatric diseases II: mood disorders / Dhavendra Kumar -- Asthma and chronic obstructive pulmonary disease / William O.C. Cookson -- Inflammatory bowel disease / Saad Pathan and Derek Jewell -- Genomics and cancer: mechanisms and applications / Mark Davies and Julian Sampson -- Hematological malignancies: the paradigm of acute myeloid leukemia / Kenneth I. Mills and Alan Burnett -- Genomics and infectious diseases: susceptibility, resistance, antimicrobial therapy / Sarra E. Jamiesson and Christopher S. Peacock. Rheumatoid arthritis and related arthropathies / Pille Harrison and Paul Wordsworth -- Immunological disorders / Tineke C.M.T. van der Pouw Kraan and Cornelis L. Verweij -- Applications in clinical pediatrics / Michael R. Konikoff and Michael D. Bates -- Learning and behavioral disorders / Lucy Raymound and James Cox -- Complex ophthalmic disorders / Forbes D.C. Manson, Andrew R. Webster, and Graeme C.M. Black -- Application in audiological medicine / Lut van Laer and Guy van Camp -- Complex skin diseases I: psoriasis / Colin Veal and David Burden -- Complex skin diseases II: atopic dermatitis / Nilesh Morar -- Diseases of the epidermis and appendages, skin pigmentation and skin cancer / Eugene Healy [and others] -- Osteoporosis and related disorders / Yoshiji Yamada -- Applications in obstetrics and gynecology and reproductive medicine / Gareth C. Weston, Anna Ponnampalam, and Peter A.W. Rogers -- Stem cell genomics, and regenerative medicine / Philip Gaughwin, Wai-Leong Tam, and Bing Lim -- Part III. Health genomics. Genomics and global health / Sir David Weatherall and Dhavendra Kumar -- Genetic testing and genomic screening / Angus Clarke -- Ethical, legal, and social issues (ELSI) / Michael Parker -- The regulation of human genomics research / Jane Kaye. Print version record. An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30,000 genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease. This advance has also laid the foundation for a broad range of genomic tools that have opened the way for targeted genetic testing in a number of medical disorders. This book is designed to be the first major text to discuss genomics-based advances in disease susceptibility, diagnosis, prognostication,and prediction of treatment outcomes in various areas of medicine. After building a strong underpinning in the basic concepts of genomics, the authors of this book, all leaders in the field, proceed to discuss a wide range of clinical areas and the applications now afforded by genomic analysis. Medical genetics. http://id.loc.gov/authorities/subjects/sh85082937 Genomics. http://id.loc.gov/authorities/subjects/sh2002000809 Clinical medicine. http://id.loc.gov/authorities/subjects/sh85083129 Pharmacogenetics. http://id.loc.gov/authorities/subjects/sh85100595 Clinical Medicine Genetic Predisposition to Disease Pharmacogenetics Genetics, Medical https://id.nlm.nih.gov/mesh/D005826 Genomics https://id.nlm.nih.gov/mesh/D023281 Génétique médicale. Génomique. Médecine clinique. Pharmacogénétique. HEALTH & FITNESS Diseases Genetic. bisacsh MEDICAL Genetics. bisacsh Pharmacogenetics fast Clinical medicine fast Genomics fast Medical genetics fast Electronic books. Kumar, Dhavendra. Weatherall, D. J. Print version: Genomics and clinical medicine. Oxford ; New York : Oxford University Press, 2008 9780195188134 (DLC) 2006034212 (OCoLC)73927254 Oxford monographs on medical genetics ; no. 53. http://id.loc.gov/authorities/names/n42018416 |
| spellingShingle | Genomics and clinical medicine / Oxford monographs on medical genetics ; Part I. General genomics. From genes to genomes: a historical perspective / Ian Dunham and Don Powell -- The human genome: structure and organization / Andrew Read -- Human functional genomics and proteomics / Yoshiji Yamada, Sahoko Ichiahara, and Masaharu Takemura -- Epigenomics and human disease / Santiago Uribe Lewis, Christopher Everett, and Richard Festenstein -- Genomic perspective of human development / Dhavendra Kumar -- Genetic and genomic approaches to taxonomy of human disease / Dhavendra Kumar -- Genomic technologies / Ian M. Frayling -- Nutritional genomics / Patrick J. Stover -- Pharmacogenomics: drug development, drug response, and precision medicines / Michelle Penny and Duncan McHale -- Part II. Clinical genomics. Clinical medicine in the genome era: an introduction / Dhavendra Kumar -- Complex cardiovascular disorders / Dan E. Arking -- Diabetes mellitus and obesity / Mark I. McCarthy -- Chronic renal disease / Albert C.M. Ong and A. Peter Maxwell -- Hemostasis and thrombosis / John H. McVet and Edward G.D. Tuddenham -- Disorders of platelets / Wadie F. Bahou -- Applications in critical care medicine / Christopher S. Garrard, Charles Hinds, and Julian Knight -- The epilepsies / Mark Gardiner -- Neurodegenerative disorders: tauopathies and synucleinopathies / Huw R. Morris and Andrew Singleton -- Neuropsychiatric disease I: schizophrenia / Patrick F. Sullivan -- Neuropsychiatric diseases II: mood disorders / Dhavendra Kumar -- Asthma and chronic obstructive pulmonary disease / William O.C. Cookson -- Inflammatory bowel disease / Saad Pathan and Derek Jewell -- Genomics and cancer: mechanisms and applications / Mark Davies and Julian Sampson -- Hematological malignancies: the paradigm of acute myeloid leukemia / Kenneth I. Mills and Alan Burnett -- Genomics and infectious diseases: susceptibility, resistance, antimicrobial therapy / Sarra E. Jamiesson and Christopher S. Peacock. Rheumatoid arthritis and related arthropathies / Pille Harrison and Paul Wordsworth -- Immunological disorders / Tineke C.M.T. van der Pouw Kraan and Cornelis L. Verweij -- Applications in clinical pediatrics / Michael R. Konikoff and Michael D. Bates -- Learning and behavioral disorders / Lucy Raymound and James Cox -- Complex ophthalmic disorders / Forbes D.C. Manson, Andrew R. Webster, and Graeme C.M. Black -- Application in audiological medicine / Lut van Laer and Guy van Camp -- Complex skin diseases I: psoriasis / Colin Veal and David Burden -- Complex skin diseases II: atopic dermatitis / Nilesh Morar -- Diseases of the epidermis and appendages, skin pigmentation and skin cancer / Eugene Healy [and others] -- Osteoporosis and related disorders / Yoshiji Yamada -- Applications in obstetrics and gynecology and reproductive medicine / Gareth C. Weston, Anna Ponnampalam, and Peter A.W. Rogers -- Stem cell genomics, and regenerative medicine / Philip Gaughwin, Wai-Leong Tam, and Bing Lim -- Part III. Health genomics. Genomics and global health / Sir David Weatherall and Dhavendra Kumar -- Genetic testing and genomic screening / Angus Clarke -- Ethical, legal, and social issues (ELSI) / Michael Parker -- The regulation of human genomics research / Jane Kaye. Medical genetics. http://id.loc.gov/authorities/subjects/sh85082937 Genomics. http://id.loc.gov/authorities/subjects/sh2002000809 Clinical medicine. http://id.loc.gov/authorities/subjects/sh85083129 Pharmacogenetics. http://id.loc.gov/authorities/subjects/sh85100595 Clinical Medicine Genetic Predisposition to Disease Pharmacogenetics Genetics, Medical https://id.nlm.nih.gov/mesh/D005826 Genomics https://id.nlm.nih.gov/mesh/D023281 Génétique médicale. Génomique. Médecine clinique. Pharmacogénétique. HEALTH & FITNESS Diseases Genetic. bisacsh MEDICAL Genetics. bisacsh Pharmacogenetics fast Clinical medicine fast Genomics fast Medical genetics fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85082937 http://id.loc.gov/authorities/subjects/sh2002000809 http://id.loc.gov/authorities/subjects/sh85083129 http://id.loc.gov/authorities/subjects/sh85100595 https://id.nlm.nih.gov/mesh/D005826 https://id.nlm.nih.gov/mesh/D023281 |
| title | Genomics and clinical medicine / |
| title_auth | Genomics and clinical medicine / |
| title_exact_search | Genomics and clinical medicine / |
| title_full | Genomics and clinical medicine / edited by Dhavendra Kumar ; advisory editor, Sir David Weatherall. |
| title_fullStr | Genomics and clinical medicine / edited by Dhavendra Kumar ; advisory editor, Sir David Weatherall. |
| title_full_unstemmed | Genomics and clinical medicine / edited by Dhavendra Kumar ; advisory editor, Sir David Weatherall. |
| title_short | Genomics and clinical medicine / |
| title_sort | genomics and clinical medicine |
| topic | Medical genetics. http://id.loc.gov/authorities/subjects/sh85082937 Genomics. http://id.loc.gov/authorities/subjects/sh2002000809 Clinical medicine. http://id.loc.gov/authorities/subjects/sh85083129 Pharmacogenetics. http://id.loc.gov/authorities/subjects/sh85100595 Clinical Medicine Genetic Predisposition to Disease Pharmacogenetics Genetics, Medical https://id.nlm.nih.gov/mesh/D005826 Genomics https://id.nlm.nih.gov/mesh/D023281 Génétique médicale. Génomique. Médecine clinique. Pharmacogénétique. HEALTH & FITNESS Diseases Genetic. bisacsh MEDICAL Genetics. bisacsh Pharmacogenetics fast Clinical medicine fast Genomics fast Medical genetics fast |
| topic_facet | Medical genetics. Genomics. Clinical medicine. Pharmacogenetics. Clinical Medicine Genetic Predisposition to Disease Pharmacogenetics Genetics, Medical Genomics Génétique médicale. Génomique. Médecine clinique. Pharmacogénétique. HEALTH & FITNESS Diseases Genetic. MEDICAL Genetics. Clinical medicine Medical genetics Electronic books. |
| work_keys_str_mv | AT kumardhavendra genomicsandclinicalmedicine AT weatheralldj genomicsandclinicalmedicine |