Using Animal Models in Biomedical Research :: a Primer for the Investigator /
Animal models play crucial roles in the continuum of experimental activities that make up biomedical research. Such in vivo modes are especially important in proof-of-principle experiments and in establishing the preclinical safety and efficacy data required for progressing to human clinical trials....
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Weitere Verfasser: | , |
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Hackensack, NJ :
World Scientific,
©2008.
|
| Schlagworte: | |
| Online-Zugang: | DE-862 DE-863 |
| Zusammenfassung: | Animal models play crucial roles in the continuum of experimental activities that make up biomedical research. Such in vivo modes are especially important in proof-of-principle experiments and in establishing the preclinical safety and efficacy data required for progressing to human clinical trials. A practical understanding of the choice, care and use of animal models is thus expected and required of all biomedical researchers. However, while both legislations and the practice of laboratory animal science have made great advances in the last decade and have impacted significantly on the use o. |
| Beschreibung: | 1 online resource (xviii, 290 pages :) |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9789812812025 9812812024 1281960888 9781281960887 9786611960889 6611960880 |
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| 100 | 1 | |a Chow, Pierce K. H. | |
| 245 | 1 | 0 | |a Using Animal Models in Biomedical Research : |b a Primer for the Investigator / |c Pierce K.H. Chow, Robert T.H. Ng, Bryan E. Ogden. |
| 260 | |a Hackensack, NJ : |b World Scientific, |c ©2008. | ||
| 300 | |a 1 online resource (xviii, 290 pages :) | ||
| 336 | |a text |b txt |2 rdacontent | ||
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| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a 1. Scientific considerations and choice of species. The rationale for the use of animal models in biomedical research / Pierce Chow. Experimental animal models in biomedical research / Robert Ng. Nonhuman primates as models in biomedical research / Jason Vilano and Bryan Ogden -- 2. Regulatory considerations in the use of animal models. Laws, regulations and guidelines for biomedical research in Singapore / Boon Theng Kuah. The functions of the institutional animal care and use committee / Pierce Chow. Responsibilities of principal investigators and research protocol evaluation / Hock Soo Ong. The 3r's, research variables and the use of alternatives / Hock Soo Ong. Use of statistics as determinant for number of animals used / Huihua Li. The advantages of accreditation with AAALAC / Bryan Ogden -- 3. Animal handling and surgical procedures. General handling, restraint, oral dosing/gavage and injections in laboratory animals / Bryan Ogden. Blood collection from laboratory animals / Jason Villano. Antibiotic coverage and therapy / Darvi Sergio. Animal preparation and transport / Robert Ng. Preparation and implementation of animal surgery / Robert Ng. Animal intubation / Robert Ng. Anaesthesia and maintenance of homeostasis / Robert Ng. animal euthanasia / Darvi Sergio. Rodent sentinel programme / Peik Khin Tan. | |
| 505 | 0 | |a 4. Basic animal investigative methods. Bioimaging in animals / David Ng [and others]. Histology sampling and techniques / In Chin Song. Animal tissue perfusion and preservation / Robert Ng. Animal cell culture / Peggy Yong and Kai Zhang. Application of microsurgical techniques in animal research / Bien Keem Tan [and others] -- 5. Animal welfare considerations. Species specific caging configuration and design / Cindy Phua. Postoperative care and pain management / Jason Villano. animal feeds and nutritional requirements / Peik Khin Tan -- 6. Safety management of an animal facility. Occupational health and safety programme / Angela Goh. New employee and external users orientation / Inria Kurniawan Then. Radiation safety awareness in animal research / S. Somanesan. Emergency crisis management / Irene Kee. Zoonoses and laboratory animal allergies / Jason Villano -- 7. Supporting facilities design. clinical skills laboratory / Robert Ng. Animal research supporting laboratories / Robert Ng. animal research and housing facilities / Robert Ng -- 8. The development of comprehensive animal facilities in Singapore. History of the Department of Experimental Surgery as a reflection of translational research development in Singapore / Robert Ng -- Append. 1. Accredited laboratories for import of experimental animals -- Append. 2. Radiation safety data -- Append. 3. Anaesthesia for laboratory animals -- Append. 4. Analgesics and therapeutics for laboratory animals -- Append. 5. Passively transmitted zoonotic organisms. | |
| 588 | 0 | |a Print version record. | |
| 520 | |a Animal models play crucial roles in the continuum of experimental activities that make up biomedical research. Such in vivo modes are especially important in proof-of-principle experiments and in establishing the preclinical safety and efficacy data required for progressing to human clinical trials. A practical understanding of the choice, care and use of animal models is thus expected and required of all biomedical researchers. However, while both legislations and the practice of laboratory animal science have made great advances in the last decade and have impacted significantly on the use o. | ||
| 546 | |a English. | ||
| 650 | 0 | |a Animal models in research. |0 http://id.loc.gov/authorities/subjects/sh85005212 | |
| 650 | 0 | |a Medicine |x Research. |0 http://id.loc.gov/authorities/subjects/sh85083097 | |
| 650 | 0 | |a Laboratory animals. |0 http://id.loc.gov/authorities/subjects/sh85073746 | |
| 650 | 2 | |a Models, Animal | |
| 650 | 2 | |a Animals, Laboratory | |
| 650 | 2 | |a Biomedical Research |x methods | |
| 650 | 6 | |a Modèles animaux dans la recherche. | |
| 650 | 6 | |a Médecine |x Recherche. | |
| 650 | 6 | |a Animaux de laboratoire. | |
| 650 | 7 | |a MEDICAL |x Research. |2 bisacsh | |
| 650 | 7 | |a Laboratory animals |2 fast | |
| 650 | 7 | |a Animal models in research |2 fast | |
| 650 | 7 | |a Medicine |x Research |2 fast | |
| 700 | 1 | |a Ng, Robert T. H. |0 http://id.loc.gov/authorities/names/n2008182127 | |
| 700 | 1 | |a Ogden, Bryan E. |0 http://id.loc.gov/authorities/names/n2008182128 | |
| 758 | |i has work: |a Using Animal Models in Biomedical Research (Text) |1 https://id.oclc.org/worldcat/entity/E39PCFxDbgGt4pXRPm6YhF8Ttq |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Chow, Pierce K.H. |t Using animal models in biomedical research. |d Hackensack, NJ : World Scientific, ©2008 |w (DLC) 2008297674 |
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Datensatz im Suchindex
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| adam_text | |
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| author | Chow, Pierce K. H. |
| author2 | Ng, Robert T. H. Ogden, Bryan E. |
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| author_GND | http://id.loc.gov/authorities/names/n2008182127 http://id.loc.gov/authorities/names/n2008182128 |
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| contents | 1. Scientific considerations and choice of species. The rationale for the use of animal models in biomedical research / Pierce Chow. Experimental animal models in biomedical research / Robert Ng. Nonhuman primates as models in biomedical research / Jason Vilano and Bryan Ogden -- 2. Regulatory considerations in the use of animal models. Laws, regulations and guidelines for biomedical research in Singapore / Boon Theng Kuah. The functions of the institutional animal care and use committee / Pierce Chow. Responsibilities of principal investigators and research protocol evaluation / Hock Soo Ong. The 3r's, research variables and the use of alternatives / Hock Soo Ong. Use of statistics as determinant for number of animals used / Huihua Li. The advantages of accreditation with AAALAC / Bryan Ogden -- 3. Animal handling and surgical procedures. General handling, restraint, oral dosing/gavage and injections in laboratory animals / Bryan Ogden. Blood collection from laboratory animals / Jason Villano. Antibiotic coverage and therapy / Darvi Sergio. Animal preparation and transport / Robert Ng. Preparation and implementation of animal surgery / Robert Ng. Animal intubation / Robert Ng. Anaesthesia and maintenance of homeostasis / Robert Ng. animal euthanasia / Darvi Sergio. Rodent sentinel programme / Peik Khin Tan. 4. Basic animal investigative methods. Bioimaging in animals / David Ng [and others]. Histology sampling and techniques / In Chin Song. Animal tissue perfusion and preservation / Robert Ng. Animal cell culture / Peggy Yong and Kai Zhang. Application of microsurgical techniques in animal research / Bien Keem Tan [and others] -- 5. Animal welfare considerations. Species specific caging configuration and design / Cindy Phua. Postoperative care and pain management / Jason Villano. animal feeds and nutritional requirements / Peik Khin Tan -- 6. Safety management of an animal facility. Occupational health and safety programme / Angela Goh. New employee and external users orientation / Inria Kurniawan Then. Radiation safety awareness in animal research / S. Somanesan. Emergency crisis management / Irene Kee. Zoonoses and laboratory animal allergies / Jason Villano -- 7. Supporting facilities design. clinical skills laboratory / Robert Ng. Animal research supporting laboratories / Robert Ng. animal research and housing facilities / Robert Ng -- 8. The development of comprehensive animal facilities in Singapore. History of the Department of Experimental Surgery as a reflection of translational research development in Singapore / Robert Ng -- Append. 1. Accredited laboratories for import of experimental animals -- Append. 2. Radiation safety data -- Append. 3. Anaesthesia for laboratory animals -- Append. 4. Analgesics and therapeutics for laboratory animals -- Append. 5. Passively transmitted zoonotic organisms. |
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| dewey-ones | 610 - Medicine and health |
| dewey-raw | 610.284 |
| dewey-search | 610.284 |
| dewey-sort | 3610.284 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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| id | ZDB-4-EBA-ocn560635766 |
| illustrated | Illustrated |
| indexdate | 2025-03-18T14:14:57Z |
| institution | BVB |
| isbn | 9789812812025 9812812024 1281960888 9781281960887 9786611960889 6611960880 |
| language | English |
| lccn | 2008297674 |
| oclc_num | 560635766 |
| open_access_boolean | |
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| physical | 1 online resource (xviii, 290 pages :) |
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| publishDateSearch | 2008 |
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| publisher | World Scientific, |
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| spelling | Chow, Pierce K. H. Using Animal Models in Biomedical Research : a Primer for the Investigator / Pierce K.H. Chow, Robert T.H. Ng, Bryan E. Ogden. Hackensack, NJ : World Scientific, ©2008. 1 online resource (xviii, 290 pages :) text txt rdacontent computer c rdamedia online resource cr rdacarrier Includes bibliographical references and index. 1. Scientific considerations and choice of species. The rationale for the use of animal models in biomedical research / Pierce Chow. Experimental animal models in biomedical research / Robert Ng. Nonhuman primates as models in biomedical research / Jason Vilano and Bryan Ogden -- 2. Regulatory considerations in the use of animal models. Laws, regulations and guidelines for biomedical research in Singapore / Boon Theng Kuah. The functions of the institutional animal care and use committee / Pierce Chow. Responsibilities of principal investigators and research protocol evaluation / Hock Soo Ong. The 3r's, research variables and the use of alternatives / Hock Soo Ong. Use of statistics as determinant for number of animals used / Huihua Li. The advantages of accreditation with AAALAC / Bryan Ogden -- 3. Animal handling and surgical procedures. General handling, restraint, oral dosing/gavage and injections in laboratory animals / Bryan Ogden. Blood collection from laboratory animals / Jason Villano. Antibiotic coverage and therapy / Darvi Sergio. Animal preparation and transport / Robert Ng. Preparation and implementation of animal surgery / Robert Ng. Animal intubation / Robert Ng. Anaesthesia and maintenance of homeostasis / Robert Ng. animal euthanasia / Darvi Sergio. Rodent sentinel programme / Peik Khin Tan. 4. Basic animal investigative methods. Bioimaging in animals / David Ng [and others]. Histology sampling and techniques / In Chin Song. Animal tissue perfusion and preservation / Robert Ng. Animal cell culture / Peggy Yong and Kai Zhang. Application of microsurgical techniques in animal research / Bien Keem Tan [and others] -- 5. Animal welfare considerations. Species specific caging configuration and design / Cindy Phua. Postoperative care and pain management / Jason Villano. animal feeds and nutritional requirements / Peik Khin Tan -- 6. Safety management of an animal facility. Occupational health and safety programme / Angela Goh. New employee and external users orientation / Inria Kurniawan Then. Radiation safety awareness in animal research / S. Somanesan. Emergency crisis management / Irene Kee. Zoonoses and laboratory animal allergies / Jason Villano -- 7. Supporting facilities design. clinical skills laboratory / Robert Ng. Animal research supporting laboratories / Robert Ng. animal research and housing facilities / Robert Ng -- 8. The development of comprehensive animal facilities in Singapore. History of the Department of Experimental Surgery as a reflection of translational research development in Singapore / Robert Ng -- Append. 1. Accredited laboratories for import of experimental animals -- Append. 2. Radiation safety data -- Append. 3. Anaesthesia for laboratory animals -- Append. 4. Analgesics and therapeutics for laboratory animals -- Append. 5. Passively transmitted zoonotic organisms. Print version record. Animal models play crucial roles in the continuum of experimental activities that make up biomedical research. Such in vivo modes are especially important in proof-of-principle experiments and in establishing the preclinical safety and efficacy data required for progressing to human clinical trials. A practical understanding of the choice, care and use of animal models is thus expected and required of all biomedical researchers. However, while both legislations and the practice of laboratory animal science have made great advances in the last decade and have impacted significantly on the use o. English. Animal models in research. http://id.loc.gov/authorities/subjects/sh85005212 Medicine Research. http://id.loc.gov/authorities/subjects/sh85083097 Laboratory animals. http://id.loc.gov/authorities/subjects/sh85073746 Models, Animal Animals, Laboratory Biomedical Research methods Modèles animaux dans la recherche. Médecine Recherche. Animaux de laboratoire. MEDICAL Research. bisacsh Laboratory animals fast Animal models in research fast Medicine Research fast Ng, Robert T. H. http://id.loc.gov/authorities/names/n2008182127 Ogden, Bryan E. http://id.loc.gov/authorities/names/n2008182128 has work: Using Animal Models in Biomedical Research (Text) https://id.oclc.org/worldcat/entity/E39PCFxDbgGt4pXRPm6YhF8Ttq https://id.oclc.org/worldcat/ontology/hasWork Print version: Chow, Pierce K.H. Using animal models in biomedical research. Hackensack, NJ : World Scientific, ©2008 (DLC) 2008297674 |
| spellingShingle | Chow, Pierce K. H. Using Animal Models in Biomedical Research : a Primer for the Investigator / 1. Scientific considerations and choice of species. The rationale for the use of animal models in biomedical research / Pierce Chow. Experimental animal models in biomedical research / Robert Ng. Nonhuman primates as models in biomedical research / Jason Vilano and Bryan Ogden -- 2. Regulatory considerations in the use of animal models. Laws, regulations and guidelines for biomedical research in Singapore / Boon Theng Kuah. The functions of the institutional animal care and use committee / Pierce Chow. Responsibilities of principal investigators and research protocol evaluation / Hock Soo Ong. The 3r's, research variables and the use of alternatives / Hock Soo Ong. Use of statistics as determinant for number of animals used / Huihua Li. The advantages of accreditation with AAALAC / Bryan Ogden -- 3. Animal handling and surgical procedures. General handling, restraint, oral dosing/gavage and injections in laboratory animals / Bryan Ogden. Blood collection from laboratory animals / Jason Villano. Antibiotic coverage and therapy / Darvi Sergio. Animal preparation and transport / Robert Ng. Preparation and implementation of animal surgery / Robert Ng. Animal intubation / Robert Ng. Anaesthesia and maintenance of homeostasis / Robert Ng. animal euthanasia / Darvi Sergio. Rodent sentinel programme / Peik Khin Tan. 4. Basic animal investigative methods. Bioimaging in animals / David Ng [and others]. Histology sampling and techniques / In Chin Song. Animal tissue perfusion and preservation / Robert Ng. Animal cell culture / Peggy Yong and Kai Zhang. Application of microsurgical techniques in animal research / Bien Keem Tan [and others] -- 5. Animal welfare considerations. Species specific caging configuration and design / Cindy Phua. Postoperative care and pain management / Jason Villano. animal feeds and nutritional requirements / Peik Khin Tan -- 6. Safety management of an animal facility. Occupational health and safety programme / Angela Goh. New employee and external users orientation / Inria Kurniawan Then. Radiation safety awareness in animal research / S. Somanesan. Emergency crisis management / Irene Kee. Zoonoses and laboratory animal allergies / Jason Villano -- 7. Supporting facilities design. clinical skills laboratory / Robert Ng. Animal research supporting laboratories / Robert Ng. animal research and housing facilities / Robert Ng -- 8. The development of comprehensive animal facilities in Singapore. History of the Department of Experimental Surgery as a reflection of translational research development in Singapore / Robert Ng -- Append. 1. Accredited laboratories for import of experimental animals -- Append. 2. Radiation safety data -- Append. 3. Anaesthesia for laboratory animals -- Append. 4. Analgesics and therapeutics for laboratory animals -- Append. 5. Passively transmitted zoonotic organisms. Animal models in research. http://id.loc.gov/authorities/subjects/sh85005212 Medicine Research. http://id.loc.gov/authorities/subjects/sh85083097 Laboratory animals. http://id.loc.gov/authorities/subjects/sh85073746 Models, Animal Animals, Laboratory Biomedical Research methods Modèles animaux dans la recherche. Médecine Recherche. Animaux de laboratoire. MEDICAL Research. bisacsh Laboratory animals fast Animal models in research fast Medicine Research fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85005212 http://id.loc.gov/authorities/subjects/sh85083097 http://id.loc.gov/authorities/subjects/sh85073746 |
| title | Using Animal Models in Biomedical Research : a Primer for the Investigator / |
| title_auth | Using Animal Models in Biomedical Research : a Primer for the Investigator / |
| title_exact_search | Using Animal Models in Biomedical Research : a Primer for the Investigator / |
| title_full | Using Animal Models in Biomedical Research : a Primer for the Investigator / Pierce K.H. Chow, Robert T.H. Ng, Bryan E. Ogden. |
| title_fullStr | Using Animal Models in Biomedical Research : a Primer for the Investigator / Pierce K.H. Chow, Robert T.H. Ng, Bryan E. Ogden. |
| title_full_unstemmed | Using Animal Models in Biomedical Research : a Primer for the Investigator / Pierce K.H. Chow, Robert T.H. Ng, Bryan E. Ogden. |
| title_short | Using Animal Models in Biomedical Research : |
| title_sort | using animal models in biomedical research a primer for the investigator |
| title_sub | a Primer for the Investigator / |
| topic | Animal models in research. http://id.loc.gov/authorities/subjects/sh85005212 Medicine Research. http://id.loc.gov/authorities/subjects/sh85083097 Laboratory animals. http://id.loc.gov/authorities/subjects/sh85073746 Models, Animal Animals, Laboratory Biomedical Research methods Modèles animaux dans la recherche. Médecine Recherche. Animaux de laboratoire. MEDICAL Research. bisacsh Laboratory animals fast Animal models in research fast Medicine Research fast |
| topic_facet | Animal models in research. Medicine Research. Laboratory animals. Models, Animal Animals, Laboratory Biomedical Research methods Modèles animaux dans la recherche. Médecine Recherche. Animaux de laboratoire. MEDICAL Research. Laboratory animals Animal models in research Medicine Research |
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