The activities of bacterial pathogens in vivo :: based on contributions to a Royal Society discussion meeting ; London, UK, meeting held on 20-21 October 1999 /
Pathogenic bacteria have unique biological properties, which enable them to invade a host and cause sickness. The molecular bases of these biological properties are the determinants of pathogenicity, and the research objectives are to recognize them, identify them chemically and relate their structu...
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| Weitere Verfasser: | , , , , |
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
London :
Imperial College Press,
2001.
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| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | Pathogenic bacteria have unique biological properties, which enable them to invade a host and cause sickness. The molecular bases of these biological properties are the determinants of pathogenicity, and the research objectives are to recognize them, identify them chemically and relate their structure to function. Most of our present knowledge comes from studies with cultures in vitro. However, there is a rising interest in bacterial behaviour in the infected host and new methods have been developed for studying it. This book describes those methods and shows how they, and a recent surge in conventional studies, are shedding light on the activities of bacterial pathogens in vivo. It discusses bacterial and host factors that operate in vivo to cause illness, showing how phenomena recognized in vitro relate to behaviour in vivo and, if evidence of relevance is not available now, indicating how it might be obtained. |
| Beschreibung: | Originally published in the "Philosophical transactions of the Royal Society" series B in 2000. |
| Beschreibung: | 1 online resource (xii, 396 pages) : illustrations |
| Bibliographie: | Includes bibliographical references at chapter ends, and index. |
| ISBN: | 9781848161610 1848161611 |
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| 245 | 0 | 4 | |a The activities of bacterial pathogens in vivo : |b based on contributions to a Royal Society discussion meeting ; London, UK, meeting held on 20-21 October 1999 / |c editors, H. Smith, C. J. Dorman, G. Dougan, D. W. Holden, [and] P. Williams. |
| 260 | |a London : |b Imperial College Press, |c 2001. | ||
| 300 | |a 1 online resource (xii, 396 pages) : |b illustrations | ||
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| 500 | |a Originally published in the "Philosophical transactions of the Royal Society" series B in 2000. | ||
| 504 | |a Includes bibliographical references at chapter ends, and index. | ||
| 505 | 0 | 0 | |t Introduction ; |t Questions about the behaviour of bacterial pathogens in vivo / |r H. Smith -- |t DNA topology and adaptation of Salmonella typhimurium to an intracellular environment / |r D. G. Marshall, |r C. J. Dorman, |r F. Bowe, |r C. Hale, and |r G. Dougan -- |
| 505 | 0 | 0 | |t New methods for studying bacterial behaviour in vivo ; |t The pathogenesis of Shigella flexneri infection : lessons from in vitro and in vivo studies / |r D. J. Philpott, |r J. D. Edgeworth, and |r P. J. Sansonetti -- |t Detection and analysis of gene expression during infection by in vivo expression technology / |r D. S. Merrell and |r A. Camilli -- |t Measurement of bacterial gene expression in vivo / |r J. Hautefort and |r J. C. D. Hinton -- |t Identification and analysis of bacterial virulence genes in vivo / |r K. E. Unsworth and |r D. W. Holden -- |t Salmonella interactions with host cells : in vitro to in vivo / |r B. B. Finlay and |r J. H. Brumell -- |
| 505 | 0 | 0 | |t Impact of the new methods ; |t In vivo gene expression and the adaptive response : from pathogenesis to vaccines and antimicrobials / |r D. M. Heithoff, |r R. L. Sinsheimer, |r D. A. Low, and |r M. J. Mahan -- |t Challenge of investigating biologically relevant functions of virulence factors in bacterial pathogens / |r R. Moxon and |r C. Tang -- |t Virulence gene regulation inside and outside / |r V. J. DiRita, |r N. C. Engleberg, |r A. Heath, |r A. Miller, |r J. A. Crawford, and |r R. Yu -- |
| 505 | 0 | 0 | |t Evidence for operation in vivo of aspects of pathogenicity revealed by recent work in vitro : potential use of new methods ; |t Quorum sensing and the population-dependent control of virulence / |r P. Williams, |r M. Camara, |r A. Hardman, |r S. Swift, |r V. J. Hope, |r K. Winzer, |r B. Middleton, |r D. I. Pritchard, |r B. W. Bycroft, and |r D. Milton -- |t Type III secretion : a bacterial device for close combat with cells of their eukaryotic host / |r G. R. Cornelis -- |t Evolution of microbial pathogens / |r J. Morschhäuser, |r G. Köhler, |r W. Ziebuhr, |r G. Blum-Oehler, |r U. Dobrindt, and |r J. Hacker -- |t The immune responses to bacterial antigens encountered in vivo at mucosal surfaces / |r G. Dougan, |r M. Ghaem-Maghami, |r D. Pickard, |r G. Frankel, |r G. Douce, |r S. Clare, |r S. Dunstan, and |r C. Simmons. |
| 520 | |a Pathogenic bacteria have unique biological properties, which enable them to invade a host and cause sickness. The molecular bases of these biological properties are the determinants of pathogenicity, and the research objectives are to recognize them, identify them chemically and relate their structure to function. Most of our present knowledge comes from studies with cultures in vitro. However, there is a rising interest in bacterial behaviour in the infected host and new methods have been developed for studying it. This book describes those methods and shows how they, and a recent surge in conventional studies, are shedding light on the activities of bacterial pathogens in vivo. It discusses bacterial and host factors that operate in vivo to cause illness, showing how phenomena recognized in vitro relate to behaviour in vivo and, if evidence of relevance is not available now, indicating how it might be obtained. | ||
| 588 | 0 | |a Print version record. | |
| 650 | 0 | |a Virulence (Microbiology) |v Congresses. | |
| 650 | 0 | |a Bacterial diseases |v Congresses. | |
| 650 | 0 | |a Pathogenic bacteria |v Congresses. | |
| 650 | 0 | |a Host-bacteria relationships |x Research |x Methodology |v Congresses. | |
| 650 | 0 | |a Molecular microbiology |v Congresses. | |
| 650 | 1 | 2 | |a Bacteria |x pathogenicity |0 https://id.nlm.nih.gov/mesh/D001419Q000472 |
| 650 | 2 | 2 | |a Molecular Biology |0 https://id.nlm.nih.gov/mesh/D008967 |
| 650 | 2 | 2 | |a Virulence |x genetics |0 https://id.nlm.nih.gov/mesh/D014774Q000235 |
| 650 | 6 | |a Maladies bactériennes |v Congrès. | |
| 650 | 6 | |a Bactéries pathogènes |v Congrès. | |
| 650 | 6 | |a Relations hôte-bactérie |x Recherche |x Méthodologie |v Congrès. | |
| 650 | 6 | |a Microbiologie moléculaire |v Congrès. | |
| 650 | 7 | |a MEDICAL |x Microbiology. |2 bisacsh | |
| 650 | 7 | |a Bacterial diseases |2 fast | |
| 650 | 7 | |a Molecular microbiology |2 fast | |
| 650 | 7 | |a Pathogenic bacteria |2 fast | |
| 650 | 7 | |a Virulence (Microbiology) |2 fast | |
| 655 | 2 | |a Congress |0 https://id.nlm.nih.gov/mesh/D016423 | |
| 655 | 7 | |a proceedings (reports) |2 aat | |
| 655 | 7 | |a Conference papers and proceedings |2 fast | |
| 655 | 7 | |a Conference papers and proceedings. |2 lcgft |0 http://id.loc.gov/authorities/genreForms/gf2014026068 | |
| 655 | 7 | |a Actes de congrès. |2 rvmgf | |
| 700 | 1 | |a Smith, Harry, |d 1921-2011, |e editor. |1 https://id.oclc.org/worldcat/entity/E39PBJfRB6PDfWRPFPQQG7bcfq |0 http://id.loc.gov/authorities/names/n81143870 | |
| 700 | 1 | |a Dorman, Charles J., |e editor. |0 http://id.loc.gov/authorities/names/n93083780 | |
| 700 | 1 | |a Dougan, G. |e editor. | |
| 700 | 1 | |a Holden, D. W. |e editor. | |
| 700 | 1 | |a Williams, P. |e editor. | |
| 710 | 2 | |a Royal Society (Great Britain) |0 http://id.loc.gov/authorities/names/n79127772 | |
| 758 | |i has work: |a The activities of bacterial pathogens in vivo (Text) |1 https://id.oclc.org/worldcat/entity/E39PCGC4M7CfVqHbT7FHGrWbMK |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
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Datensatz im Suchindex
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| author2 | Smith, Harry, 1921-2011 Dorman, Charles J. Dougan, G. Holden, D. W. Williams, P. |
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| author_GND | http://id.loc.gov/authorities/names/n81143870 http://id.loc.gov/authorities/names/n93083780 |
| author_additional | H. Smith -- D. G. Marshall, C. J. Dorman, F. Bowe, C. Hale, and G. Dougan -- D. J. Philpott, J. D. Edgeworth, and P. J. Sansonetti -- D. S. Merrell and A. Camilli -- J. Hautefort and J. C. D. Hinton -- K. E. Unsworth and D. W. Holden -- B. B. Finlay and J. H. Brumell -- D. M. Heithoff, R. L. Sinsheimer, D. A. Low, and M. J. Mahan -- R. Moxon and C. Tang -- V. J. DiRita, N. C. Engleberg, A. Heath, A. Miller, J. A. Crawford, and R. Yu -- P. Williams, M. Camara, A. Hardman, S. Swift, V. J. Hope, K. Winzer, B. Middleton, D. I. Pritchard, B. W. Bycroft, and D. Milton -- G. R. Cornelis -- J. Morschhäuser, G. Köhler, W. Ziebuhr, G. Blum-Oehler, U. Dobrindt, and J. Hacker -- G. Dougan, M. Ghaem-Maghami, D. Pickard, G. Frankel, G. Douce, S. Clare, S. Dunstan, and C. Simmons. |
| author_corporate | Royal Society (Great Britain) |
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| contents | Introduction ; Questions about the behaviour of bacterial pathogens in vivo / DNA topology and adaptation of Salmonella typhimurium to an intracellular environment / New methods for studying bacterial behaviour in vivo ; The pathogenesis of Shigella flexneri infection : lessons from in vitro and in vivo studies / Detection and analysis of gene expression during infection by in vivo expression technology / Measurement of bacterial gene expression in vivo / Identification and analysis of bacterial virulence genes in vivo / Salmonella interactions with host cells : in vitro to in vivo / Impact of the new methods ; In vivo gene expression and the adaptive response : from pathogenesis to vaccines and antimicrobials / Challenge of investigating biologically relevant functions of virulence factors in bacterial pathogens / Virulence gene regulation inside and outside / Evidence for operation in vivo of aspects of pathogenicity revealed by recent work in vitro : potential use of new methods ; Quorum sensing and the population-dependent control of virulence / Type III secretion : a bacterial device for close combat with cells of their eukaryotic host / Evolution of microbial pathogens / The immune responses to bacterial antigens encountered in vivo at mucosal surfaces / |
| ctrlnum | (OCoLC)261123543 |
| dewey-full | 616.014 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.014 |
| dewey-search | 616.014 |
| dewey-sort | 3616.014 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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| genre | Congress https://id.nlm.nih.gov/mesh/D016423 proceedings (reports) aat Conference papers and proceedings fast Conference papers and proceedings. lcgft http://id.loc.gov/authorities/genreForms/gf2014026068 Actes de congrès. rvmgf |
| genre_facet | Congress proceedings (reports) Conference papers and proceedings Conference papers and proceedings. Actes de congrès. |
| id | ZDB-4-EBA-ocn261123543 |
| illustrated | Illustrated |
| indexdate | 2024-11-27T13:16:32Z |
| institution | BVB |
| institution_GND | http://id.loc.gov/authorities/names/n79127772 |
| isbn | 9781848161610 1848161611 |
| language | English |
| oclc_num | 261123543 |
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| owner_facet | MAIN DE-863 DE-BY-FWS |
| physical | 1 online resource (xii, 396 pages) : illustrations |
| psigel | ZDB-4-EBA |
| publishDate | 2001 |
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| publisher | Imperial College Press, |
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| spelling | The activities of bacterial pathogens in vivo : based on contributions to a Royal Society discussion meeting ; London, UK, meeting held on 20-21 October 1999 / editors, H. Smith, C. J. Dorman, G. Dougan, D. W. Holden, [and] P. Williams. London : Imperial College Press, 2001. 1 online resource (xii, 396 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier data file Originally published in the "Philosophical transactions of the Royal Society" series B in 2000. Includes bibliographical references at chapter ends, and index. Introduction ; Questions about the behaviour of bacterial pathogens in vivo / H. Smith -- DNA topology and adaptation of Salmonella typhimurium to an intracellular environment / D. G. Marshall, C. J. Dorman, F. Bowe, C. Hale, and G. Dougan -- New methods for studying bacterial behaviour in vivo ; The pathogenesis of Shigella flexneri infection : lessons from in vitro and in vivo studies / D. J. Philpott, J. D. Edgeworth, and P. J. Sansonetti -- Detection and analysis of gene expression during infection by in vivo expression technology / D. S. Merrell and A. Camilli -- Measurement of bacterial gene expression in vivo / J. Hautefort and J. C. D. Hinton -- Identification and analysis of bacterial virulence genes in vivo / K. E. Unsworth and D. W. Holden -- Salmonella interactions with host cells : in vitro to in vivo / B. B. Finlay and J. H. Brumell -- Impact of the new methods ; In vivo gene expression and the adaptive response : from pathogenesis to vaccines and antimicrobials / D. M. Heithoff, R. L. Sinsheimer, D. A. Low, and M. J. Mahan -- Challenge of investigating biologically relevant functions of virulence factors in bacterial pathogens / R. Moxon and C. Tang -- Virulence gene regulation inside and outside / V. J. DiRita, N. C. Engleberg, A. Heath, A. Miller, J. A. Crawford, and R. Yu -- Evidence for operation in vivo of aspects of pathogenicity revealed by recent work in vitro : potential use of new methods ; Quorum sensing and the population-dependent control of virulence / P. Williams, M. Camara, A. Hardman, S. Swift, V. J. Hope, K. Winzer, B. Middleton, D. I. Pritchard, B. W. Bycroft, and D. Milton -- Type III secretion : a bacterial device for close combat with cells of their eukaryotic host / G. R. Cornelis -- Evolution of microbial pathogens / J. Morschhäuser, G. Köhler, W. Ziebuhr, G. Blum-Oehler, U. Dobrindt, and J. Hacker -- The immune responses to bacterial antigens encountered in vivo at mucosal surfaces / G. Dougan, M. Ghaem-Maghami, D. Pickard, G. Frankel, G. Douce, S. Clare, S. Dunstan, and C. Simmons. Pathogenic bacteria have unique biological properties, which enable them to invade a host and cause sickness. The molecular bases of these biological properties are the determinants of pathogenicity, and the research objectives are to recognize them, identify them chemically and relate their structure to function. Most of our present knowledge comes from studies with cultures in vitro. However, there is a rising interest in bacterial behaviour in the infected host and new methods have been developed for studying it. This book describes those methods and shows how they, and a recent surge in conventional studies, are shedding light on the activities of bacterial pathogens in vivo. It discusses bacterial and host factors that operate in vivo to cause illness, showing how phenomena recognized in vitro relate to behaviour in vivo and, if evidence of relevance is not available now, indicating how it might be obtained. Print version record. Virulence (Microbiology) Congresses. Bacterial diseases Congresses. Pathogenic bacteria Congresses. Host-bacteria relationships Research Methodology Congresses. Molecular microbiology Congresses. Bacteria pathogenicity https://id.nlm.nih.gov/mesh/D001419Q000472 Molecular Biology https://id.nlm.nih.gov/mesh/D008967 Virulence genetics https://id.nlm.nih.gov/mesh/D014774Q000235 Maladies bactériennes Congrès. Bactéries pathogènes Congrès. Relations hôte-bactérie Recherche Méthodologie Congrès. Microbiologie moléculaire Congrès. MEDICAL Microbiology. bisacsh Bacterial diseases fast Molecular microbiology fast Pathogenic bacteria fast Virulence (Microbiology) fast Congress https://id.nlm.nih.gov/mesh/D016423 proceedings (reports) aat Conference papers and proceedings fast Conference papers and proceedings. lcgft http://id.loc.gov/authorities/genreForms/gf2014026068 Actes de congrès. rvmgf Smith, Harry, 1921-2011, editor. https://id.oclc.org/worldcat/entity/E39PBJfRB6PDfWRPFPQQG7bcfq http://id.loc.gov/authorities/names/n81143870 Dorman, Charles J., editor. http://id.loc.gov/authorities/names/n93083780 Dougan, G. editor. Holden, D. W. editor. Williams, P. editor. Royal Society (Great Britain) http://id.loc.gov/authorities/names/n79127772 has work: The activities of bacterial pathogens in vivo (Text) https://id.oclc.org/worldcat/entity/E39PCGC4M7CfVqHbT7FHGrWbMK https://id.oclc.org/worldcat/ontology/hasWork Print version: Activities of bacterial pathogens in vivo. London : Imperial College Press, 2001 1860942725 9781860942723 (DLC) 2002277434 (OCoLC)49240230 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=235536 Volltext |
| spellingShingle | The activities of bacterial pathogens in vivo : based on contributions to a Royal Society discussion meeting ; London, UK, meeting held on 20-21 October 1999 / Introduction ; Questions about the behaviour of bacterial pathogens in vivo / DNA topology and adaptation of Salmonella typhimurium to an intracellular environment / New methods for studying bacterial behaviour in vivo ; The pathogenesis of Shigella flexneri infection : lessons from in vitro and in vivo studies / Detection and analysis of gene expression during infection by in vivo expression technology / Measurement of bacterial gene expression in vivo / Identification and analysis of bacterial virulence genes in vivo / Salmonella interactions with host cells : in vitro to in vivo / Impact of the new methods ; In vivo gene expression and the adaptive response : from pathogenesis to vaccines and antimicrobials / Challenge of investigating biologically relevant functions of virulence factors in bacterial pathogens / Virulence gene regulation inside and outside / Evidence for operation in vivo of aspects of pathogenicity revealed by recent work in vitro : potential use of new methods ; Quorum sensing and the population-dependent control of virulence / Type III secretion : a bacterial device for close combat with cells of their eukaryotic host / Evolution of microbial pathogens / The immune responses to bacterial antigens encountered in vivo at mucosal surfaces / Virulence (Microbiology) Congresses. Bacterial diseases Congresses. Pathogenic bacteria Congresses. Host-bacteria relationships Research Methodology Congresses. Molecular microbiology Congresses. Bacteria pathogenicity https://id.nlm.nih.gov/mesh/D001419Q000472 Molecular Biology https://id.nlm.nih.gov/mesh/D008967 Virulence genetics https://id.nlm.nih.gov/mesh/D014774Q000235 Maladies bactériennes Congrès. Bactéries pathogènes Congrès. Relations hôte-bactérie Recherche Méthodologie Congrès. Microbiologie moléculaire Congrès. MEDICAL Microbiology. bisacsh Bacterial diseases fast Molecular microbiology fast Pathogenic bacteria fast Virulence (Microbiology) fast |
| subject_GND | https://id.nlm.nih.gov/mesh/D001419Q000472 https://id.nlm.nih.gov/mesh/D008967 https://id.nlm.nih.gov/mesh/D014774Q000235 https://id.nlm.nih.gov/mesh/D016423 http://id.loc.gov/authorities/genreForms/gf2014026068 |
| title | The activities of bacterial pathogens in vivo : based on contributions to a Royal Society discussion meeting ; London, UK, meeting held on 20-21 October 1999 / |
| title_alt | Introduction ; Questions about the behaviour of bacterial pathogens in vivo / DNA topology and adaptation of Salmonella typhimurium to an intracellular environment / New methods for studying bacterial behaviour in vivo ; The pathogenesis of Shigella flexneri infection : lessons from in vitro and in vivo studies / Detection and analysis of gene expression during infection by in vivo expression technology / Measurement of bacterial gene expression in vivo / Identification and analysis of bacterial virulence genes in vivo / Salmonella interactions with host cells : in vitro to in vivo / Impact of the new methods ; In vivo gene expression and the adaptive response : from pathogenesis to vaccines and antimicrobials / Challenge of investigating biologically relevant functions of virulence factors in bacterial pathogens / Virulence gene regulation inside and outside / Evidence for operation in vivo of aspects of pathogenicity revealed by recent work in vitro : potential use of new methods ; Quorum sensing and the population-dependent control of virulence / Type III secretion : a bacterial device for close combat with cells of their eukaryotic host / Evolution of microbial pathogens / The immune responses to bacterial antigens encountered in vivo at mucosal surfaces / |
| title_auth | The activities of bacterial pathogens in vivo : based on contributions to a Royal Society discussion meeting ; London, UK, meeting held on 20-21 October 1999 / |
| title_exact_search | The activities of bacterial pathogens in vivo : based on contributions to a Royal Society discussion meeting ; London, UK, meeting held on 20-21 October 1999 / |
| title_full | The activities of bacterial pathogens in vivo : based on contributions to a Royal Society discussion meeting ; London, UK, meeting held on 20-21 October 1999 / editors, H. Smith, C. J. Dorman, G. Dougan, D. W. Holden, [and] P. Williams. |
| title_fullStr | The activities of bacterial pathogens in vivo : based on contributions to a Royal Society discussion meeting ; London, UK, meeting held on 20-21 October 1999 / editors, H. Smith, C. J. Dorman, G. Dougan, D. W. Holden, [and] P. Williams. |
| title_full_unstemmed | The activities of bacterial pathogens in vivo : based on contributions to a Royal Society discussion meeting ; London, UK, meeting held on 20-21 October 1999 / editors, H. Smith, C. J. Dorman, G. Dougan, D. W. Holden, [and] P. Williams. |
| title_short | The activities of bacterial pathogens in vivo : |
| title_sort | activities of bacterial pathogens in vivo based on contributions to a royal society discussion meeting london uk meeting held on 20 21 october 1999 |
| title_sub | based on contributions to a Royal Society discussion meeting ; London, UK, meeting held on 20-21 October 1999 / |
| topic | Virulence (Microbiology) Congresses. Bacterial diseases Congresses. Pathogenic bacteria Congresses. Host-bacteria relationships Research Methodology Congresses. Molecular microbiology Congresses. Bacteria pathogenicity https://id.nlm.nih.gov/mesh/D001419Q000472 Molecular Biology https://id.nlm.nih.gov/mesh/D008967 Virulence genetics https://id.nlm.nih.gov/mesh/D014774Q000235 Maladies bactériennes Congrès. Bactéries pathogènes Congrès. Relations hôte-bactérie Recherche Méthodologie Congrès. Microbiologie moléculaire Congrès. MEDICAL Microbiology. bisacsh Bacterial diseases fast Molecular microbiology fast Pathogenic bacteria fast Virulence (Microbiology) fast |
| topic_facet | Virulence (Microbiology) Congresses. Bacterial diseases Congresses. Pathogenic bacteria Congresses. Host-bacteria relationships Research Methodology Congresses. Molecular microbiology Congresses. Bacteria pathogenicity Molecular Biology Virulence genetics Maladies bactériennes Congrès. Bactéries pathogènes Congrès. Relations hôte-bactérie Recherche Méthodologie Congrès. Microbiologie moléculaire Congrès. MEDICAL Microbiology. Bacterial diseases Molecular microbiology Pathogenic bacteria Virulence (Microbiology) Congress proceedings (reports) Conference papers and proceedings Conference papers and proceedings. Actes de congrès. |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=235536 |
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