Control and the therapeutic trial :: rhetoric and experimentation in Britain, 1918-48 /
Annotation How do doctors decide whether their drugs, or other treatments, actually work? In practice this can be fiendishly difficult. Nowadays the gold standard is the randomised controlled trial (RCT). But the RCT is a recent invention, and the story of how it came to dominate therapeutic evaluat...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Amsterdam ; New York, NY :
Rodopi,
2007.
|
| Schriftenreihe: | Wellcome series in the history of medicine.
Clio medica (Amsterdam, Netherlands) ; 82. |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | Annotation How do doctors decide whether their drugs, or other treatments, actually work? In practice this can be fiendishly difficult. Nowadays the gold standard is the randomised controlled trial (RCT). But the RCT is a recent invention, and the story of how it came to dominate therapeutic evaluation from the latter half of the twentieth century involves acrimony, confrontation, and manipulation of the powerful rhetoric of 'control?. Control and the Therapeutic Trial examines the development of the RCT from the eclectic collection of methodologies available to practitioners in the early-twentieth century. In particular, it explores the British Medical Research Council?s (MRC) exploitation of the term 'controlled? to help establish its own 'controlled trials? as the gold standard for therapeutic evaluation, and, ultimately, the MRC itself as the proper authority to adjudicate on therapeutic efficacy. This rhetorical power still clings, and is exploited today. Control and the Therapeutic Trial will be of interest not only to historians of twentieth-century medicine and practising clinicians who take therapeutic decisions, but to anyone who seeks a broader insight into the forces that shaped, and control, the modern controlled trial. |
| Beschreibung: | 1 online resource (221 pages) : illustrations |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9781435616394 1435616391 9789401204941 9401204942 |
| ISSN: | 0045-7183 ; |
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| 245 | 1 | 0 | |a Control and the therapeutic trial : |b rhetoric and experimentation in Britain, 1918-48 / |c Martin Edwards. |
| 260 | |a Amsterdam ; |a New York, NY : |b Rodopi, |c 2007. | ||
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| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 520 | 8 | |a Annotation How do doctors decide whether their drugs, or other treatments, actually work? In practice this can be fiendishly difficult. Nowadays the gold standard is the randomised controlled trial (RCT). But the RCT is a recent invention, and the story of how it came to dominate therapeutic evaluation from the latter half of the twentieth century involves acrimony, confrontation, and manipulation of the powerful rhetoric of 'control?. Control and the Therapeutic Trial examines the development of the RCT from the eclectic collection of methodologies available to practitioners in the early-twentieth century. In particular, it explores the British Medical Research Council?s (MRC) exploitation of the term 'controlled? to help establish its own 'controlled trials? as the gold standard for therapeutic evaluation, and, ultimately, the MRC itself as the proper authority to adjudicate on therapeutic efficacy. This rhetorical power still clings, and is exploited today. Control and the Therapeutic Trial will be of interest not only to historians of twentieth-century medicine and practising clinicians who take therapeutic decisions, but to anyone who seeks a broader insight into the forces that shaped, and control, the modern controlled trial. | |
| 505 | 0 | |a CONTROL AND THE THERAPEUTIC TRIAL; Contents; Acknowledgements; Note on National Archives Source Material; Introduction; 1. No Word is Innocent: The History and Rhetoric of Controlled Trials prior to 1948; 2. Good, Bad or Offal? The Rhetoric of Control in the Evaluation of Raw Pancreas Therapy; 3. Bright Lights, Smoky Cities: Light Therapy in 1920s Britain; 4. Control and the MRC's Evaluation of Serum Therapy for Pneumonia, 1929-34; 5. Keeping it Controlled: The MRC's Trials of Immunisation against Influenza. | |
| 505 | 8 | |a 6. Whose Words are they Anyway? The Contrasting Strategies of Almroth Wright and Bradford Hill to Capture the Nomenclature of Controlled Trials7. Conclusion: What's Controlled about the Controlled Trial?; Bibliography; Index. | |
| 650 | 0 | |a Clinical trials |x History. | |
| 650 | 2 | |a Controlled Clinical Trials as Topic |x history | |
| 650 | 6 | |a Études cliniques |x Histoire. | |
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| 650 | 7 | |a MEDICAL |x Healing. |2 bisacsh | |
| 650 | 7 | |a HEALTH & FITNESS |x Healing. |2 bisacsh | |
| 650 | 7 | |a BODY, MIND & SPIRIT |x Healing |x General. |2 bisacsh | |
| 650 | 7 | |a Clinical trials |2 fast | |
| 650 | 7 | |a Forschung |2 gnd | |
| 650 | 7 | |a Medizin |2 gnd | |
| 650 | 7 | |a Wissenschaftsentwicklung |2 gnd |0 http://d-nb.info/gnd/4079355-2 | |
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| 651 | 7 | |a Großbritannien |2 gnd | |
| 655 | 7 | |a History |2 fast | |
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| contents | CONTROL AND THE THERAPEUTIC TRIAL; Contents; Acknowledgements; Note on National Archives Source Material; Introduction; 1. No Word is Innocent: The History and Rhetoric of Controlled Trials prior to 1948; 2. Good, Bad or Offal? The Rhetoric of Control in the Evaluation of Raw Pancreas Therapy; 3. Bright Lights, Smoky Cities: Light Therapy in 1920s Britain; 4. Control and the MRC's Evaluation of Serum Therapy for Pneumonia, 1929-34; 5. Keeping it Controlled: The MRC's Trials of Immunisation against Influenza. 6. Whose Words are they Anyway? The Contrasting Strategies of Almroth Wright and Bradford Hill to Capture the Nomenclature of Controlled Trials7. Conclusion: What's Controlled about the Controlled Trial?; Bibliography; Index. |
| ctrlnum | (OCoLC)190597402 |
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| dewey-ones | 615 - Pharmacology and therapeutics |
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In practice this can be fiendishly difficult. Nowadays the gold standard is the randomised controlled trial (RCT). But the RCT is a recent invention, and the story of how it came to dominate therapeutic evaluation from the latter half of the twentieth century involves acrimony, confrontation, and manipulation of the powerful rhetoric of 'control?. Control and the Therapeutic Trial examines the development of the RCT from the eclectic collection of methodologies available to practitioners in the early-twentieth century. In particular, it explores the British Medical Research Council?s (MRC) exploitation of the term 'controlled? to help establish its own 'controlled trials? as the gold standard for therapeutic evaluation, and, ultimately, the MRC itself as the proper authority to adjudicate on therapeutic efficacy. This rhetorical power still clings, and is exploited today. 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The Contrasting Strategies of Almroth Wright and Bradford Hill to Capture the Nomenclature of Controlled Trials7. 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| genre | History fast |
| genre_facet | History |
| geographic | Großbritannien gnd |
| geographic_facet | Großbritannien |
| id | ZDB-4-EBA-ocn190597402 |
| illustrated | Illustrated |
| indexdate | 2024-11-27T13:16:14Z |
| institution | BVB |
| isbn | 9781435616394 1435616391 9789401204941 9401204942 |
| issn | 0045-7183 ; |
| language | English |
| oclc_num | 190597402 |
| open_access_boolean | |
| owner | MAIN DE-863 DE-BY-FWS |
| owner_facet | MAIN DE-863 DE-BY-FWS |
| physical | 1 online resource (221 pages) : illustrations |
| psigel | ZDB-4-EBA |
| publishDate | 2007 |
| publishDateSearch | 2007 |
| publishDateSort | 2007 |
| publisher | Rodopi, |
| record_format | marc |
| series | Wellcome series in the history of medicine. Clio medica (Amsterdam, Netherlands) ; |
| series2 | Wellcome series in the history of medicine Clio medica, |
| spelling | Edwards, Martin. Control and the therapeutic trial : rhetoric and experimentation in Britain, 1918-48 / Martin Edwards. Amsterdam ; New York, NY : Rodopi, 2007. 1 online resource (221 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier data file Wellcome series in the history of medicine Clio medica, 0045-7183 ; 82 Includes bibliographical references and index. Print version record. Annotation How do doctors decide whether their drugs, or other treatments, actually work? In practice this can be fiendishly difficult. Nowadays the gold standard is the randomised controlled trial (RCT). But the RCT is a recent invention, and the story of how it came to dominate therapeutic evaluation from the latter half of the twentieth century involves acrimony, confrontation, and manipulation of the powerful rhetoric of 'control?. Control and the Therapeutic Trial examines the development of the RCT from the eclectic collection of methodologies available to practitioners in the early-twentieth century. In particular, it explores the British Medical Research Council?s (MRC) exploitation of the term 'controlled? to help establish its own 'controlled trials? as the gold standard for therapeutic evaluation, and, ultimately, the MRC itself as the proper authority to adjudicate on therapeutic efficacy. This rhetorical power still clings, and is exploited today. Control and the Therapeutic Trial will be of interest not only to historians of twentieth-century medicine and practising clinicians who take therapeutic decisions, but to anyone who seeks a broader insight into the forces that shaped, and control, the modern controlled trial. CONTROL AND THE THERAPEUTIC TRIAL; Contents; Acknowledgements; Note on National Archives Source Material; Introduction; 1. No Word is Innocent: The History and Rhetoric of Controlled Trials prior to 1948; 2. Good, Bad or Offal? The Rhetoric of Control in the Evaluation of Raw Pancreas Therapy; 3. Bright Lights, Smoky Cities: Light Therapy in 1920s Britain; 4. Control and the MRC's Evaluation of Serum Therapy for Pneumonia, 1929-34; 5. Keeping it Controlled: The MRC's Trials of Immunisation against Influenza. 6. Whose Words are they Anyway? The Contrasting Strategies of Almroth Wright and Bradford Hill to Capture the Nomenclature of Controlled Trials7. Conclusion: What's Controlled about the Controlled Trial?; Bibliography; Index. Clinical trials History. Controlled Clinical Trials as Topic history Études cliniques Histoire. HEALTH & FITNESS Alternative Therapies. bisacsh MEDICAL Healing. bisacsh HEALTH & FITNESS Healing. bisacsh BODY, MIND & SPIRIT Healing General. bisacsh Clinical trials fast Forschung gnd Medizin gnd Wissenschaftsentwicklung gnd http://d-nb.info/gnd/4079355-2 Kontrollierte klinische Studie gnd http://d-nb.info/gnd/4202997-1 Großbritannien gnd History fast Print version: Edwards, Martin. Control and the therapeutic trial. Amsterdam ; New York, NY : Rodopi, 2007 9789042022737 9042022736 (OCoLC)182737422 Wellcome series in the history of medicine. http://id.loc.gov/authorities/names/no2002021705 Clio medica (Amsterdam, Netherlands) ; 82. http://id.loc.gov/authorities/names/no94039729 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=213805 Volltext |
| spellingShingle | Edwards, Martin Control and the therapeutic trial : rhetoric and experimentation in Britain, 1918-48 / Wellcome series in the history of medicine. Clio medica (Amsterdam, Netherlands) ; CONTROL AND THE THERAPEUTIC TRIAL; Contents; Acknowledgements; Note on National Archives Source Material; Introduction; 1. No Word is Innocent: The History and Rhetoric of Controlled Trials prior to 1948; 2. Good, Bad or Offal? The Rhetoric of Control in the Evaluation of Raw Pancreas Therapy; 3. Bright Lights, Smoky Cities: Light Therapy in 1920s Britain; 4. Control and the MRC's Evaluation of Serum Therapy for Pneumonia, 1929-34; 5. Keeping it Controlled: The MRC's Trials of Immunisation against Influenza. 6. Whose Words are they Anyway? The Contrasting Strategies of Almroth Wright and Bradford Hill to Capture the Nomenclature of Controlled Trials7. Conclusion: What's Controlled about the Controlled Trial?; Bibliography; Index. Clinical trials History. Controlled Clinical Trials as Topic history Études cliniques Histoire. HEALTH & FITNESS Alternative Therapies. bisacsh MEDICAL Healing. bisacsh HEALTH & FITNESS Healing. bisacsh BODY, MIND & SPIRIT Healing General. bisacsh Clinical trials fast Forschung gnd Medizin gnd Wissenschaftsentwicklung gnd http://d-nb.info/gnd/4079355-2 Kontrollierte klinische Studie gnd http://d-nb.info/gnd/4202997-1 |
| subject_GND | http://d-nb.info/gnd/4079355-2 http://d-nb.info/gnd/4202997-1 |
| title | Control and the therapeutic trial : rhetoric and experimentation in Britain, 1918-48 / |
| title_auth | Control and the therapeutic trial : rhetoric and experimentation in Britain, 1918-48 / |
| title_exact_search | Control and the therapeutic trial : rhetoric and experimentation in Britain, 1918-48 / |
| title_full | Control and the therapeutic trial : rhetoric and experimentation in Britain, 1918-48 / Martin Edwards. |
| title_fullStr | Control and the therapeutic trial : rhetoric and experimentation in Britain, 1918-48 / Martin Edwards. |
| title_full_unstemmed | Control and the therapeutic trial : rhetoric and experimentation in Britain, 1918-48 / Martin Edwards. |
| title_short | Control and the therapeutic trial : |
| title_sort | control and the therapeutic trial rhetoric and experimentation in britain 1918 48 |
| title_sub | rhetoric and experimentation in Britain, 1918-48 / |
| topic | Clinical trials History. Controlled Clinical Trials as Topic history Études cliniques Histoire. HEALTH & FITNESS Alternative Therapies. bisacsh MEDICAL Healing. bisacsh HEALTH & FITNESS Healing. bisacsh BODY, MIND & SPIRIT Healing General. bisacsh Clinical trials fast Forschung gnd Medizin gnd Wissenschaftsentwicklung gnd http://d-nb.info/gnd/4079355-2 Kontrollierte klinische Studie gnd http://d-nb.info/gnd/4202997-1 |
| topic_facet | Clinical trials History. Controlled Clinical Trials as Topic history Études cliniques Histoire. HEALTH & FITNESS Alternative Therapies. MEDICAL Healing. HEALTH & FITNESS Healing. BODY, MIND & SPIRIT Healing General. Clinical trials Forschung Medizin Wissenschaftsentwicklung Kontrollierte klinische Studie Großbritannien History |
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| work_keys_str_mv | AT edwardsmartin controlandthetherapeutictrialrhetoricandexperimentationinbritain191848 |