The Ontario Cancer Institute :: successes and reverses at Sherbourne Street /
To achieve this goal the institute divided its operation into four strands: two of the strands were the research areas - the study of advanced radiation therapy and biology, which worked separatively but cooperatively; a third was patient care; and the fourth element was leadership, provided by the...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Montreal, Que. :
McGill-Queen's University Press,
©2003.
|
| Schriftenreihe: | McGill-Queen's/Associated Medical Services (Hannah Institute) studies in the history of medicine, health, and society ;
19. |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | To achieve this goal the institute divided its operation into four strands: two of the strands were the research areas - the study of advanced radiation therapy and biology, which worked separatively but cooperatively; a third was patient care; and the fourth element was leadership, provided by the clinical chiefs, the heads of the research divisions, and the administration, in particular the institute's first administrator, John Law. Together these strands helped create a philosophy that made the Ontario Cancer Institute unique and provided the basis for its national and international success. Essential to these successes was a new graduate department, Medical Biophysics, based in the University of Toronto School of Graduate Studies. This department, which provided an innovative, research-based doctoral and masters program, meant that the OCI could accurately be described as a centre for cancer treatment, research, and education. McCulloch describes how the first quantitative assay for stem cells played a major role in bringing OCI research to the international stage as well as influencing other science and much of the clinical thinking in the Institute. Other major advances that brought international recognition have been the identification of the mechanisms that allow cancer cells to resist death from the effects of a variety of different tumours and the isolation of the gene that encodes the T cell receptor, a critical part of the immune apparatus for dealing with foreign cells and viruses. McCulloch also details how lack of space to meet growing demands was a continuing source of frustration and disagreement, and how sometimes serious interpersonal problems hindered the forward thrust of development. Describing these events as well as institute's successes, he provides an insight into the history of Canada's premier cancer research centre. |
| Beschreibung: | 1 online resource (x, 183 pages) : illustrations, portraits. |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9780773570948 0773570942 1282861042 9781282861046 9786612861048 6612861045 |
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| 100 | 1 | |a McCulloch, Ernest A., |d 1926-2011. |0 http://id.loc.gov/authorities/names/n82021029 | |
| 245 | 1 | 4 | |a The Ontario Cancer Institute : |b successes and reverses at Sherbourne Street / |c E.A. McCulloch. |
| 260 | |a Montreal, Que. : |b McGill-Queen's University Press, |c ©2003. | ||
| 300 | |a 1 online resource (x, 183 pages) : |b illustrations, portraits. | ||
| 336 | |a text |b txt |2 rdacontent | ||
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| 490 | 1 | |a McGill-Queen's/Associated Medical Services (Hannah Institute) studies in the history of medicine, health, and society ; |v 19 | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 546 | |a English. | ||
| 505 | 0 | 0 | |t Front Matter -- |t Contents -- |t Preface -- |t Beginnings -- |t First Research Programs -- |t Leadership and Style -- |t Normal and Malignant Stem Cells -- |t Growth and Change -- |t Immunology and Hematology Using Cell Culture Methods -- |t Physics and Radiation Therapy -- |t The Middle Years, 1971-1981 -- |t Interface Research -- |t The Style of Ray Bush as Director -- |t Response to the Crisis of Space and Equipment -- |t Preparing to Move -- |t Last Days on Sherbourne Street -- |t Glossary -- |t Index |
| 520 | |a To achieve this goal the institute divided its operation into four strands: two of the strands were the research areas - the study of advanced radiation therapy and biology, which worked separatively but cooperatively; a third was patient care; and the fourth element was leadership, provided by the clinical chiefs, the heads of the research divisions, and the administration, in particular the institute's first administrator, John Law. Together these strands helped create a philosophy that made the Ontario Cancer Institute unique and provided the basis for its national and international success. Essential to these successes was a new graduate department, Medical Biophysics, based in the University of Toronto School of Graduate Studies. This department, which provided an innovative, research-based doctoral and masters program, meant that the OCI could accurately be described as a centre for cancer treatment, research, and education. McCulloch describes how the first quantitative assay for stem cells played a major role in bringing OCI research to the international stage as well as influencing other science and much of the clinical thinking in the Institute. Other major advances that brought international recognition have been the identification of the mechanisms that allow cancer cells to resist death from the effects of a variety of different tumours and the isolation of the gene that encodes the T cell receptor, a critical part of the immune apparatus for dealing with foreign cells and viruses. McCulloch also details how lack of space to meet growing demands was a continuing source of frustration and disagreement, and how sometimes serious interpersonal problems hindered the forward thrust of development. Describing these events as well as institute's successes, he provides an insight into the history of Canada's premier cancer research centre. | ||
| 610 | 2 | 0 | |a Ontario Cancer Institute |x History. |
| 610 | 2 | 2 | |a Ontario Cancer Institute |
| 610 | 2 | 6 | |a Ontario Cancer Institute |x Histoire. |
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| 650 | 2 | 2 | |a History, 20th Century |
| 650 | 2 | 2 | |a Neoplasms |x therapy |
| 651 | 2 | |a Ontario | |
| 650 | 6 | |a Cancer |x Recherche |z Ontario |z Toronto |x Histoire |y 20e siècle. | |
| 650 | 6 | |a Médecine |x Histoire |y 20e siècle. | |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x Cancer. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Oncology. |2 bisacsh | |
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| 776 | 0 | 8 | |i Print version: |a McCulloch, Ernest A., 1926-2011. |t Ontario Cancer Institute. |d Montreal ; Ithaca, N.Y. : McGill-Queen's University Press, ©2003 |z 9780773525252 |w (OCoLC)50843780 |
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Datensatz im Suchindex
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| author | McCulloch, Ernest A., 1926-2011 |
| author_GND | http://id.loc.gov/authorities/names/n82021029 |
| author_facet | McCulloch, Ernest A., 1926-2011 |
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| contents | Front Matter -- Contents -- Preface -- Beginnings -- First Research Programs -- Leadership and Style -- Normal and Malignant Stem Cells -- Growth and Change -- Immunology and Hematology Using Cell Culture Methods -- Physics and Radiation Therapy -- The Middle Years, 1971-1981 -- Interface Research -- The Style of Ray Bush as Director -- Response to the Crisis of Space and Equipment -- Preparing to Move -- Last Days on Sherbourne Street -- Glossary -- Index |
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| genre | History fast |
| genre_facet | History |
| geographic | Ontario Ontario Toronto fast https://id.oclc.org/worldcat/entity/E39PBJpTXwhyWg6TcM8tk47fv3 |
| geographic_facet | Ontario Ontario Toronto |
| id | ZDB-4-EBA-ocn180773018 |
| illustrated | Illustrated |
| indexdate | 2024-11-27T13:16:11Z |
| institution | BVB |
| isbn | 9780773570948 0773570942 1282861042 9781282861046 9786612861048 6612861045 |
| language | English |
| oclc_num | 180773018 |
| open_access_boolean | |
| owner | MAIN DE-863 DE-BY-FWS |
| owner_facet | MAIN DE-863 DE-BY-FWS |
| physical | 1 online resource (x, 183 pages) : illustrations, portraits. |
| psigel | ZDB-4-EBA |
| publishDate | 2003 |
| publishDateSearch | 2003 |
| publishDateSort | 2003 |
| publisher | McGill-Queen's University Press, |
| record_format | marc |
| series | McGill-Queen's/Associated Medical Services (Hannah Institute) studies in the history of medicine, health, and society ; |
| series2 | McGill-Queen's/Associated Medical Services (Hannah Institute) studies in the history of medicine, health, and society ; |
| spelling | McCulloch, Ernest A., 1926-2011. http://id.loc.gov/authorities/names/n82021029 The Ontario Cancer Institute : successes and reverses at Sherbourne Street / E.A. McCulloch. Montreal, Que. : McGill-Queen's University Press, ©2003. 1 online resource (x, 183 pages) : illustrations, portraits. text txt rdacontent computer c rdamedia online resource cr rdacarrier data file McGill-Queen's/Associated Medical Services (Hannah Institute) studies in the history of medicine, health, and society ; 19 Includes bibliographical references and index. Print version record. English. Front Matter -- Contents -- Preface -- Beginnings -- First Research Programs -- Leadership and Style -- Normal and Malignant Stem Cells -- Growth and Change -- Immunology and Hematology Using Cell Culture Methods -- Physics and Radiation Therapy -- The Middle Years, 1971-1981 -- Interface Research -- The Style of Ray Bush as Director -- Response to the Crisis of Space and Equipment -- Preparing to Move -- Last Days on Sherbourne Street -- Glossary -- Index To achieve this goal the institute divided its operation into four strands: two of the strands were the research areas - the study of advanced radiation therapy and biology, which worked separatively but cooperatively; a third was patient care; and the fourth element was leadership, provided by the clinical chiefs, the heads of the research divisions, and the administration, in particular the institute's first administrator, John Law. Together these strands helped create a philosophy that made the Ontario Cancer Institute unique and provided the basis for its national and international success. Essential to these successes was a new graduate department, Medical Biophysics, based in the University of Toronto School of Graduate Studies. This department, which provided an innovative, research-based doctoral and masters program, meant that the OCI could accurately be described as a centre for cancer treatment, research, and education. McCulloch describes how the first quantitative assay for stem cells played a major role in bringing OCI research to the international stage as well as influencing other science and much of the clinical thinking in the Institute. Other major advances that brought international recognition have been the identification of the mechanisms that allow cancer cells to resist death from the effects of a variety of different tumours and the isolation of the gene that encodes the T cell receptor, a critical part of the immune apparatus for dealing with foreign cells and viruses. McCulloch also details how lack of space to meet growing demands was a continuing source of frustration and disagreement, and how sometimes serious interpersonal problems hindered the forward thrust of development. Describing these events as well as institute's successes, he provides an insight into the history of Canada's premier cancer research centre. Ontario Cancer Institute History. Ontario Cancer Institute Ontario Cancer Institute Histoire. Ontario Cancer Institute fast Cancer Research Ontario Toronto History 20th century. Cancer Care Facilities history Biomedical Research history https://id.nlm.nih.gov/mesh/D035843Q000266 History, 20th Century Neoplasms therapy Ontario Cancer Recherche Ontario Toronto Histoire 20e siècle. Médecine Histoire 20e siècle. HEALTH & FITNESS Diseases Cancer. bisacsh MEDICAL Oncology. bisacsh Cancer Research fast Ontario Toronto fast https://id.oclc.org/worldcat/entity/E39PBJpTXwhyWg6TcM8tk47fv3 1900-1999 fast History fast has work: The Ontario Cancer Institute (Text) https://id.oclc.org/worldcat/entity/E39PCFMy9hWVGKcbkJtqfFWv73 https://id.oclc.org/worldcat/ontology/hasWork Print version: McCulloch, Ernest A., 1926-2011. Ontario Cancer Institute. Montreal ; Ithaca, N.Y. : McGill-Queen's University Press, ©2003 9780773525252 (OCoLC)50843780 McGill-Queen's/Associated Medical Services (Hannah Institute) studies in the history of medicine, health, and society ; 19. http://id.loc.gov/authorities/names/no00098871 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=404674 Volltext |
| spellingShingle | McCulloch, Ernest A., 1926-2011 The Ontario Cancer Institute : successes and reverses at Sherbourne Street / McGill-Queen's/Associated Medical Services (Hannah Institute) studies in the history of medicine, health, and society ; Front Matter -- Contents -- Preface -- Beginnings -- First Research Programs -- Leadership and Style -- Normal and Malignant Stem Cells -- Growth and Change -- Immunology and Hematology Using Cell Culture Methods -- Physics and Radiation Therapy -- The Middle Years, 1971-1981 -- Interface Research -- The Style of Ray Bush as Director -- Response to the Crisis of Space and Equipment -- Preparing to Move -- Last Days on Sherbourne Street -- Glossary -- Index Ontario Cancer Institute History. Ontario Cancer Institute Ontario Cancer Institute Histoire. Ontario Cancer Institute fast Cancer Research Ontario Toronto History 20th century. Cancer Care Facilities history Biomedical Research history https://id.nlm.nih.gov/mesh/D035843Q000266 History, 20th Century Neoplasms therapy Cancer Recherche Ontario Toronto Histoire 20e siècle. Médecine Histoire 20e siècle. HEALTH & FITNESS Diseases Cancer. bisacsh MEDICAL Oncology. bisacsh Cancer Research fast |
| subject_GND | https://id.nlm.nih.gov/mesh/D035843Q000266 |
| title | The Ontario Cancer Institute : successes and reverses at Sherbourne Street / |
| title_alt | Front Matter -- Contents -- Preface -- Beginnings -- First Research Programs -- Leadership and Style -- Normal and Malignant Stem Cells -- Growth and Change -- Immunology and Hematology Using Cell Culture Methods -- Physics and Radiation Therapy -- The Middle Years, 1971-1981 -- Interface Research -- The Style of Ray Bush as Director -- Response to the Crisis of Space and Equipment -- Preparing to Move -- Last Days on Sherbourne Street -- Glossary -- Index |
| title_auth | The Ontario Cancer Institute : successes and reverses at Sherbourne Street / |
| title_exact_search | The Ontario Cancer Institute : successes and reverses at Sherbourne Street / |
| title_full | The Ontario Cancer Institute : successes and reverses at Sherbourne Street / E.A. McCulloch. |
| title_fullStr | The Ontario Cancer Institute : successes and reverses at Sherbourne Street / E.A. McCulloch. |
| title_full_unstemmed | The Ontario Cancer Institute : successes and reverses at Sherbourne Street / E.A. McCulloch. |
| title_short | The Ontario Cancer Institute : |
| title_sort | ontario cancer institute successes and reverses at sherbourne street |
| title_sub | successes and reverses at Sherbourne Street / |
| topic | Ontario Cancer Institute History. Ontario Cancer Institute Ontario Cancer Institute Histoire. Ontario Cancer Institute fast Cancer Research Ontario Toronto History 20th century. Cancer Care Facilities history Biomedical Research history https://id.nlm.nih.gov/mesh/D035843Q000266 History, 20th Century Neoplasms therapy Cancer Recherche Ontario Toronto Histoire 20e siècle. Médecine Histoire 20e siècle. HEALTH & FITNESS Diseases Cancer. bisacsh MEDICAL Oncology. bisacsh Cancer Research fast |
| topic_facet | Ontario Cancer Institute History. Ontario Cancer Institute Ontario Cancer Institute Histoire. Cancer Research Ontario Toronto History 20th century. Cancer Care Facilities history Biomedical Research history History, 20th Century Neoplasms therapy Ontario Cancer Recherche Ontario Toronto Histoire 20e siècle. Médecine Histoire 20e siècle. HEALTH & FITNESS Diseases Cancer. MEDICAL Oncology. Cancer Research Ontario Toronto History |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=404674 |
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