Verfügbarkeit: Foundations of comparative genomics /

Foundations of comparative genomics /:

This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of...

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Bibliographische Detailangaben
1. Verfasser:	Mushegian, Arcady R.
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	Amsterdam ; Boston : Academic Press, ©2007.
Schlagworte:	Genomics. Gene mapping. Physiology, Comparative. Genetics > Technique. Genomics > methods Genetic Techniques Sequence Analysis > methods Genomics Chromosome Mapping Physiology, Comparative Génomique. Cartes chromosomiques. Physiologie comparée. Génétique > Technique. SCIENCE > Life Sciences > Genetics & Genomics. Genetics > Technique Gene mapping dissertations. Academic theses Academic theses. Thèses et écrits académiques.
Online-Zugang:	Volltext Volltext
Zusammenfassung:	This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as systems biology and whole-genome phylogenetic reconstructions. This book is an essential reference for researchers and students in computational biology, evolutionary biology, and genetics. * Presents an historic overview of genome biology and its achievements * Includes topics not covered in other books such as minimal and ancestral genomes * Discusses the evolutionary resilience of protein-coding genes and frequent functional convergence at the molecular level * Critically reviews horizontal gene transfer and other contentious issues * Covers comparative virology as a somewhat overlooked foundation of modern genome science.
Beschreibung:	1 online resource (ix, 265 pages) : illustrations
Bibliographie:	Includes bibliographical references (pages 238-257) and index.
ISBN:	9780120887941 0120887940 9780080546094 0080546099 9786611036966 6611036962

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504			\|a Includes bibliographical references (pages 238-257) and index.
505	0		\|a The beginning of computational genomics -- Finding sequence similarities -- Homology: can we get it right? -- Getting ready for the era of comparative genomics: the importance of viruses -- The first fact of comparative genomics: protein sequences are remarkably resilient in evolution -- The second fact of comparative genomics: functional convergence at the molecular level -- Prediction of function and reconstruction of metabolism from genomic data: homology-based approaches -- Prediction of function and reconstruction of metabolism: post-homology approaches -- Structural genomics: what does it tell us about life? -- How many protein families are there? -- Phylogenetic inference and the era of complete genomes -- Two stories about evolution -- Minimal and ancestral genomes -- Comparative genomics and systems biology.
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author	Mushegian, Arcady R.
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contents	The beginning of computational genomics -- Finding sequence similarities -- Homology: can we get it right? -- Getting ready for the era of comparative genomics: the importance of viruses -- The first fact of comparative genomics: protein sequences are remarkably resilient in evolution -- The second fact of comparative genomics: functional convergence at the molecular level -- Prediction of function and reconstruction of metabolism from genomic data: homology-based approaches -- Prediction of function and reconstruction of metabolism: post-homology approaches -- Structural genomics: what does it tell us about life? -- How many protein families are there? -- Phylogenetic inference and the era of complete genomes -- Two stories about evolution -- Minimal and ancestral genomes -- Comparative genomics and systems biology.
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genre	dissertations. aat Academic theses fast Academic theses. lcgft http://id.loc.gov/authorities/genreForms/gf2014026039 Thèses et écrits académiques. rvmgf
genre_facet	dissertations. Academic theses Academic theses. Thèses et écrits académiques.
id	ZDB-4-EBA-ocn162570604
illustrated	Illustrated
indexdate	2024-11-27T13:16:06Z
institution	BVB
isbn	9780120887941 0120887940 9780080546094 0080546099 9786611036966 6611036962
language	English
oclc_num	162570604
open_access_boolean
owner	MAIN DE-863 DE-BY-FWS
owner_facet	MAIN DE-863 DE-BY-FWS
physical	1 online resource (ix, 265 pages) : illustrations
psigel	ZDB-4-EBA
publishDate	2007
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publisher	Academic Press,
record_format	marc
spelling	Mushegian, Arcady R. http://id.loc.gov/authorities/names/n2007180437 Foundations of comparative genomics / Arcady R. Mushegian. Amsterdam ; Boston : Academic Press, ©2007. 1 online resource (ix, 265 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as systems biology and whole-genome phylogenetic reconstructions. This book is an essential reference for researchers and students in computational biology, evolutionary biology, and genetics. * Presents an historic overview of genome biology and its achievements * Includes topics not covered in other books such as minimal and ancestral genomes * Discusses the evolutionary resilience of protein-coding genes and frequent functional convergence at the molecular level * Critically reviews horizontal gene transfer and other contentious issues * Covers comparative virology as a somewhat overlooked foundation of modern genome science. Includes bibliographical references (pages 238-257) and index. The beginning of computational genomics -- Finding sequence similarities -- Homology: can we get it right? -- Getting ready for the era of comparative genomics: the importance of viruses -- The first fact of comparative genomics: protein sequences are remarkably resilient in evolution -- The second fact of comparative genomics: functional convergence at the molecular level -- Prediction of function and reconstruction of metabolism from genomic data: homology-based approaches -- Prediction of function and reconstruction of metabolism: post-homology approaches -- Structural genomics: what does it tell us about life? -- How many protein families are there? -- Phylogenetic inference and the era of complete genomes -- Two stories about evolution -- Minimal and ancestral genomes -- Comparative genomics and systems biology. Print version record. English. Genomics. http://id.loc.gov/authorities/subjects/sh2002000809 Gene mapping. http://id.loc.gov/authorities/subjects/sh85025386 Physiology, Comparative. http://id.loc.gov/authorities/subjects/sh85101681 Genetics Technique. http://id.loc.gov/authorities/subjects/sh85053881 Genomics methods Genetic Techniques Sequence Analysis methods Genomics https://id.nlm.nih.gov/mesh/D023281 Chromosome Mapping https://id.nlm.nih.gov/mesh/D002874 Physiology, Comparative https://id.nlm.nih.gov/mesh/D010828 Génomique. Cartes chromosomiques. Physiologie comparée. Génétique Technique. SCIENCE Life Sciences Genetics & Genomics. bisacsh Genetics Technique fast Gene mapping fast Genomics fast Physiology, Comparative fast dissertations. aat Academic theses fast Academic theses. lcgft http://id.loc.gov/authorities/genreForms/gf2014026039 Thèses et écrits académiques. rvmgf has work: Foundations of comparative genomics (Text) https://id.oclc.org/worldcat/entity/E39PCGdK4vHQq4P7XdH77JpVRX https://id.oclc.org/worldcat/ontology/hasWork Print version: Mushegian, Arcady R. Foundations of comparative genomics. Amsterdam ; Boston : Academic Press, ©2007 9780120887941 0120887940 (DLC) 2007003418 (OCoLC)81252684 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=199143 Volltext FWS01 ZDB-4-EBA FWS_PDA_EBA https://www.sciencedirect.com/science/book/9780120887941 Volltext
spellingShingle	Mushegian, Arcady R. Foundations of comparative genomics / The beginning of computational genomics -- Finding sequence similarities -- Homology: can we get it right? -- Getting ready for the era of comparative genomics: the importance of viruses -- The first fact of comparative genomics: protein sequences are remarkably resilient in evolution -- The second fact of comparative genomics: functional convergence at the molecular level -- Prediction of function and reconstruction of metabolism from genomic data: homology-based approaches -- Prediction of function and reconstruction of metabolism: post-homology approaches -- Structural genomics: what does it tell us about life? -- How many protein families are there? -- Phylogenetic inference and the era of complete genomes -- Two stories about evolution -- Minimal and ancestral genomes -- Comparative genomics and systems biology. Genomics. http://id.loc.gov/authorities/subjects/sh2002000809 Gene mapping. http://id.loc.gov/authorities/subjects/sh85025386 Physiology, Comparative. http://id.loc.gov/authorities/subjects/sh85101681 Genetics Technique. http://id.loc.gov/authorities/subjects/sh85053881 Genomics methods Genetic Techniques Sequence Analysis methods Genomics https://id.nlm.nih.gov/mesh/D023281 Chromosome Mapping https://id.nlm.nih.gov/mesh/D002874 Physiology, Comparative https://id.nlm.nih.gov/mesh/D010828 Génomique. Cartes chromosomiques. Physiologie comparée. Génétique Technique. SCIENCE Life Sciences Genetics & Genomics. bisacsh Genetics Technique fast Gene mapping fast Genomics fast Physiology, Comparative fast
subject_GND	http://id.loc.gov/authorities/subjects/sh2002000809 http://id.loc.gov/authorities/subjects/sh85025386 http://id.loc.gov/authorities/subjects/sh85101681 http://id.loc.gov/authorities/subjects/sh85053881 https://id.nlm.nih.gov/mesh/D023281 https://id.nlm.nih.gov/mesh/D002874 https://id.nlm.nih.gov/mesh/D010828 http://id.loc.gov/authorities/genreForms/gf2014026039
title	Foundations of comparative genomics /
title_auth	Foundations of comparative genomics /
title_exact_search	Foundations of comparative genomics /
title_full	Foundations of comparative genomics / Arcady R. Mushegian.
title_fullStr	Foundations of comparative genomics / Arcady R. Mushegian.
title_full_unstemmed	Foundations of comparative genomics / Arcady R. Mushegian.
title_short	Foundations of comparative genomics /
title_sort	foundations of comparative genomics
topic	Genomics. http://id.loc.gov/authorities/subjects/sh2002000809 Gene mapping. http://id.loc.gov/authorities/subjects/sh85025386 Physiology, Comparative. http://id.loc.gov/authorities/subjects/sh85101681 Genetics Technique. http://id.loc.gov/authorities/subjects/sh85053881 Genomics methods Genetic Techniques Sequence Analysis methods Genomics https://id.nlm.nih.gov/mesh/D023281 Chromosome Mapping https://id.nlm.nih.gov/mesh/D002874 Physiology, Comparative https://id.nlm.nih.gov/mesh/D010828 Génomique. Cartes chromosomiques. Physiologie comparée. Génétique Technique. SCIENCE Life Sciences Genetics & Genomics. bisacsh Genetics Technique fast Gene mapping fast Genomics fast Physiology, Comparative fast
topic_facet	Genomics. Gene mapping. Physiology, Comparative. Genetics Technique. Genomics methods Genetic Techniques Sequence Analysis methods Genomics Chromosome Mapping Physiology, Comparative Génomique. Cartes chromosomiques. Physiologie comparée. Génétique Technique. SCIENCE Life Sciences Genetics & Genomics. Genetics Technique Gene mapping dissertations. Academic theses Academic theses. Thèses et écrits académiques.
url	https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=199143 https://www.sciencedirect.com/science/book/9780120887941
work_keys_str_mv	AT mushegianarcadyr foundationsofcomparativegenomics

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