Immunology :: the making of a modern science /
Immunology has progressed in spectacular fashion in the last four decades. Studies of the response to infectious agents, transplanted organs and tumours (and the potential to manipulate that response), and the study of the immune system as a model system in molecular cell biology have yielded dramat...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
London :
Academic Press,
©1995.
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| Online-Zugang: | Volltext Volltext |
| Zusammenfassung: | Immunology has progressed in spectacular fashion in the last four decades. Studies of the response to infectious agents, transplanted organs and tumours (and the potential to manipulate that response), and the study of the immune system as a model system in molecular cell biology have yielded dramatic advances in our understanding of the mechanisms of immunity. The field has attracted a continuous stream of the brightest theoretical and experimental scientists for over forty years. This book conveys the philosophies and approaches of sixteen of the most successful of these scientists in the form of a series of narratives that describe the circumstances that led to a major discovery in immunology. Contributors not only recall an exciting period of research that helped shape modern immunology, but set it in the personal context of place and time. Jacques Miller, for example, describes the discovery of the function of the thymus, Rolf Zinkernagel explains how experiments on viral immunity led to the discovery of MHC restriction and Susumu Tonegawa provides an account of how antibody gene structure was defined. Medically-important discoveries include descriptions of early studies of autoimmunity by Noel Rose and of tumour immunology by George and Eva Klein. Far from being a collection of disinterested, historical accounts, this volume comprises a series of passionately biographical, personal essays that provide an unusually intimate insight into the scientific process. This book will be essential, and fascinating, reading for all those with an interest in immunology, and in the life sciences in general. For students and teachers, this will provide the background necessary for a true understanding of immunology, and to place subsequent discoveries in perspective. |
| Beschreibung: | Includes index. |
| Beschreibung: | 1 online resource (viii, 246 pages) : illustrations, portraits |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9780122740206 0122740203 9780080534534 0080534538 1281059056 9781281059055 9786611059057 6611059059 |
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| 520 | |a Immunology has progressed in spectacular fashion in the last four decades. Studies of the response to infectious agents, transplanted organs and tumours (and the potential to manipulate that response), and the study of the immune system as a model system in molecular cell biology have yielded dramatic advances in our understanding of the mechanisms of immunity. The field has attracted a continuous stream of the brightest theoretical and experimental scientists for over forty years. This book conveys the philosophies and approaches of sixteen of the most successful of these scientists in the form of a series of narratives that describe the circumstances that led to a major discovery in immunology. Contributors not only recall an exciting period of research that helped shape modern immunology, but set it in the personal context of place and time. Jacques Miller, for example, describes the discovery of the function of the thymus, Rolf Zinkernagel explains how experiments on viral immunity led to the discovery of MHC restriction and Susumu Tonegawa provides an account of how antibody gene structure was defined. Medically-important discoveries include descriptions of early studies of autoimmunity by Noel Rose and of tumour immunology by George and Eva Klein. Far from being a collection of disinterested, historical accounts, this volume comprises a series of passionately biographical, personal essays that provide an unusually intimate insight into the scientific process. This book will be essential, and fascinating, reading for all those with an interest in immunology, and in the life sciences in general. For students and teachers, this will provide the background necessary for a true understanding of immunology, and to place subsequent discoveries in perspective. | ||
| 505 | 0 | |a Introduction: The Historical Origins of Modern Immunology. Theories of Immunity: Origins of the Cell Selection Theories of Antibody Formation. One Cell-One Antibody. Roof of and Routes to Autoimmunology. The Cellular Basis of Immunity: The Mystery of the Lymphocyte. The Discovery of Thymus Function. The Discovery of MHC-Restricted T Cell Recognition. Two Signal Nodels of Lymphocyte Activation. Ontogeny of the Immune Response. The Molecular Basis of Immunity: The HLA Story. Early Investigations on Antibody Structure and Idiotypy. The Contribution of the Cytokine Concept to Immunology. Discovery of Antibody Gene Structure. Discovery of the T Cell Receptor. Immunology and Medicine: Organ Transplantation and the Revitalization of Immunology. Immediate Hypersensitivity, A Brief History. Tumour Immunology. Hepatitis B Virus and Vaccine. Studies of Thyroid Autoimmunity: Their Role in Shaping Modern Immunology. | |
| 500 | |a Includes index. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 546 | |a English. | ||
| 650 | 0 | |a Immunology. |0 http://id.loc.gov/authorities/subjects/sh85064579 | |
| 650 | 2 | |a Allergy and Immunology |x history | |
| 650 | 2 | |a Immunity |x history | |
| 650 | 2 | |a Allergy and Immunology |0 https://id.nlm.nih.gov/mesh/D000486 | |
| 650 | 6 | |a Immunologie. | |
| 650 | 7 | |a MEDICAL |x Immunology. |2 bisacsh | |
| 650 | 7 | |a Immunology |2 fast | |
| 650 | 1 | 7 | |a Immunologie. |2 gtt |
| 650 | 7 | |a Microbiologia. |2 larpcal | |
| 650 | 7 | |a Imunologia. |2 larpcal | |
| 653 | 0 | |a Immunology | |
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Datensatz im Suchindex
| DE-BY-FWS_katkey | ZDB-4-EBA-ocn162129480 |
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| _version_ | 1816881650480447488 |
| adam_text | |
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| author2 | Gallagher, Richard B. |
| author2_role | |
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| author_GND | http://id.loc.gov/authorities/names/n94034074 |
| author_facet | Gallagher, Richard B. |
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| contents | Introduction: The Historical Origins of Modern Immunology. Theories of Immunity: Origins of the Cell Selection Theories of Antibody Formation. One Cell-One Antibody. Roof of and Routes to Autoimmunology. The Cellular Basis of Immunity: The Mystery of the Lymphocyte. The Discovery of Thymus Function. The Discovery of MHC-Restricted T Cell Recognition. Two Signal Nodels of Lymphocyte Activation. Ontogeny of the Immune Response. The Molecular Basis of Immunity: The HLA Story. Early Investigations on Antibody Structure and Idiotypy. The Contribution of the Cytokine Concept to Immunology. Discovery of Antibody Gene Structure. Discovery of the T Cell Receptor. Immunology and Medicine: Organ Transplantation and the Revitalization of Immunology. Immediate Hypersensitivity, A Brief History. Tumour Immunology. Hepatitis B Virus and Vaccine. Studies of Thyroid Autoimmunity: Their Role in Shaping Modern Immunology. |
| ctrlnum | (OCoLC)162129480 |
| dewey-full | 616.079 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.079 |
| dewey-search | 616.079 |
| dewey-sort | 3616.079 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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| indexdate | 2024-11-27T13:16:05Z |
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| owner_facet | MAIN DE-863 DE-BY-FWS |
| physical | 1 online resource (viii, 246 pages) : illustrations, portraits |
| psigel | ZDB-4-EBA |
| publishDate | 1995 |
| publishDateSearch | 1995 |
| publishDateSort | 1995 |
| publisher | Academic Press, |
| record_format | marc |
| spelling | Immunology : the making of a modern science / edited by Richard B. Gallagher [and others]. London : Academic Press, ©1995. 1 online resource (viii, 246 pages) : illustrations, portraits text txt rdacontent computer c rdamedia online resource cr rdacarrier Immunology has progressed in spectacular fashion in the last four decades. Studies of the response to infectious agents, transplanted organs and tumours (and the potential to manipulate that response), and the study of the immune system as a model system in molecular cell biology have yielded dramatic advances in our understanding of the mechanisms of immunity. The field has attracted a continuous stream of the brightest theoretical and experimental scientists for over forty years. This book conveys the philosophies and approaches of sixteen of the most successful of these scientists in the form of a series of narratives that describe the circumstances that led to a major discovery in immunology. Contributors not only recall an exciting period of research that helped shape modern immunology, but set it in the personal context of place and time. Jacques Miller, for example, describes the discovery of the function of the thymus, Rolf Zinkernagel explains how experiments on viral immunity led to the discovery of MHC restriction and Susumu Tonegawa provides an account of how antibody gene structure was defined. Medically-important discoveries include descriptions of early studies of autoimmunity by Noel Rose and of tumour immunology by George and Eva Klein. Far from being a collection of disinterested, historical accounts, this volume comprises a series of passionately biographical, personal essays that provide an unusually intimate insight into the scientific process. This book will be essential, and fascinating, reading for all those with an interest in immunology, and in the life sciences in general. For students and teachers, this will provide the background necessary for a true understanding of immunology, and to place subsequent discoveries in perspective. Introduction: The Historical Origins of Modern Immunology. Theories of Immunity: Origins of the Cell Selection Theories of Antibody Formation. One Cell-One Antibody. Roof of and Routes to Autoimmunology. The Cellular Basis of Immunity: The Mystery of the Lymphocyte. The Discovery of Thymus Function. The Discovery of MHC-Restricted T Cell Recognition. Two Signal Nodels of Lymphocyte Activation. Ontogeny of the Immune Response. The Molecular Basis of Immunity: The HLA Story. Early Investigations on Antibody Structure and Idiotypy. The Contribution of the Cytokine Concept to Immunology. Discovery of Antibody Gene Structure. Discovery of the T Cell Receptor. Immunology and Medicine: Organ Transplantation and the Revitalization of Immunology. Immediate Hypersensitivity, A Brief History. Tumour Immunology. Hepatitis B Virus and Vaccine. Studies of Thyroid Autoimmunity: Their Role in Shaping Modern Immunology. Includes index. Includes bibliographical references and index. Print version record. English. Immunology. http://id.loc.gov/authorities/subjects/sh85064579 Allergy and Immunology history Immunity history Allergy and Immunology https://id.nlm.nih.gov/mesh/D000486 Immunologie. MEDICAL Immunology. bisacsh Immunology fast Immunologie. gtt Microbiologia. larpcal Imunologia. larpcal Immunology Electronic books. Essay essays. aat Essays fast Essays. lcgft http://id.loc.gov/authorities/genreForms/gf2014026094 Essais. rvmgf Gallagher, Richard B. http://id.loc.gov/authorities/names/n94034074 has work: Immunology (Text) https://id.oclc.org/worldcat/entity/E39PCH6FDJTgvfjhXmcyBFXMrq https://id.oclc.org/worldcat/ontology/hasWork Print version: Immunology. London : Academic Press, ©1995 0122740203 9780122740206 (OCoLC)33207307 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=210377 Volltext FWS01 ZDB-4-EBA FWS_PDA_EBA https://www.sciencedirect.com/science/book/9780122740206 Volltext |
| spellingShingle | Immunology : the making of a modern science / Introduction: The Historical Origins of Modern Immunology. Theories of Immunity: Origins of the Cell Selection Theories of Antibody Formation. One Cell-One Antibody. Roof of and Routes to Autoimmunology. The Cellular Basis of Immunity: The Mystery of the Lymphocyte. The Discovery of Thymus Function. The Discovery of MHC-Restricted T Cell Recognition. Two Signal Nodels of Lymphocyte Activation. Ontogeny of the Immune Response. The Molecular Basis of Immunity: The HLA Story. Early Investigations on Antibody Structure and Idiotypy. The Contribution of the Cytokine Concept to Immunology. Discovery of Antibody Gene Structure. Discovery of the T Cell Receptor. Immunology and Medicine: Organ Transplantation and the Revitalization of Immunology. Immediate Hypersensitivity, A Brief History. Tumour Immunology. Hepatitis B Virus and Vaccine. Studies of Thyroid Autoimmunity: Their Role in Shaping Modern Immunology. Immunology. http://id.loc.gov/authorities/subjects/sh85064579 Allergy and Immunology history Immunity history Allergy and Immunology https://id.nlm.nih.gov/mesh/D000486 Immunologie. MEDICAL Immunology. bisacsh Immunology fast Immunologie. gtt Microbiologia. larpcal Imunologia. larpcal |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85064579 https://id.nlm.nih.gov/mesh/D000486 http://id.loc.gov/authorities/genreForms/gf2014026094 |
| title | Immunology : the making of a modern science / |
| title_auth | Immunology : the making of a modern science / |
| title_exact_search | Immunology : the making of a modern science / |
| title_full | Immunology : the making of a modern science / edited by Richard B. Gallagher [and others]. |
| title_fullStr | Immunology : the making of a modern science / edited by Richard B. Gallagher [and others]. |
| title_full_unstemmed | Immunology : the making of a modern science / edited by Richard B. Gallagher [and others]. |
| title_short | Immunology : |
| title_sort | immunology the making of a modern science |
| title_sub | the making of a modern science / |
| topic | Immunology. http://id.loc.gov/authorities/subjects/sh85064579 Allergy and Immunology history Immunity history Allergy and Immunology https://id.nlm.nih.gov/mesh/D000486 Immunologie. MEDICAL Immunology. bisacsh Immunology fast Immunologie. gtt Microbiologia. larpcal Imunologia. larpcal |
| topic_facet | Immunology. Allergy and Immunology history Immunity history Allergy and Immunology Immunologie. MEDICAL Immunology. Immunology Microbiologia. Imunologia. Electronic books. Essay essays. Essays Essays. Essais. |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=210377 https://www.sciencedirect.com/science/book/9780122740206 |
| work_keys_str_mv | AT gallagherrichardb immunologythemakingofamodernscience |