The Mouse in biomedical research.: Immunology / Volume IV :
Immunology, the fourth volume in the four volume set, The Mouse in Biomedical Research, is a completely new addition to this series, dedicated to mouse immunology. It is based on the vast body of knowledge which has made the mouse the model of choice when studying immunity in man. Arguably more is k...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Amsterdam ; Boston :
Academic Press,
©2007.
|
| Ausgabe: | 2nd ed. |
| Schriftenreihe: | American College of Laboratory Animal Medicine series.
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | Immunology, the fourth volume in the four volume set, The Mouse in Biomedical Research, is a completely new addition to this series, dedicated to mouse immunology. It is based on the vast body of knowledge which has made the mouse the model of choice when studying immunity in man. Arguably more is known about the immune system in mice than any other species except man. In large part this is due to the power of genetic engineering to delineate molecular mechanisms. In this volume we present an Overview to mouse immunology, including both the innate and adaptive immune systems, followed by 15 chapters, each dealing with a specific area of immunology in the mouse. These chapters illustrate the power of genetic engineering in dissecting each component of the immune response from the development of lymphoid tissues to signal transduction pathways in activated cells. |
| Beschreibung: | 1 online resource (1 volume (xvi, 374 pages)) : illustrations (some color) |
| Bibliographie: | Includes bibliographical references and indexes. |
| ISBN: | 9780080469089 0080469086 |
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| 245 | 0 | 4 | |a The Mouse in biomedical research. |n Volume IV : |b Immunology / |c edited by James G. Fox [and others]. |
| 246 | 3 | 0 | |a Immunology |
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| 260 | |a Amsterdam ; |a Boston : |b Academic Press, |c ©2007. | ||
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| 505 | 0 | |a Cover -- Copyright page -- Table of Contents -- List of Reviewers for Chapters in this Volume -- Contributors -- Foreword for Volume IV -- Preface -- Overview: Overview of Immunology in the Mouse: Molecular and Cellular Immunology -- Chapter 1: The Molecular Basis of Lymphoid Architecture in the Mouse -- Chapter 2: The Biology of Toll-Like Receptors in Mice -- Chapter 3: Genomic Organization of the Mouse Major Histocompatibility Complex -- Chapter 4: Some Biological Features of Dendritic Cells in the Mouse -- Chapter 5: Mouse Models Revealed the Mechanisms for Somatic Hypermutation and Class Switch Recombination of Immunoglobulin Genes -- Chapter 6: Mouse Natural Killer Cells: Function and Activation -- Chapter 7: Cytokine-Activated JAK-STAT Signaling in the Mouse Immune System -- Chapter 8: Signal Transduction Events Regulating Integrin Function and T Cell Migration in the Mouse -- Chapter 9: Mouse Models of Negative Selection -- Chapter 10: Peripheral Tolerance of T Cells in the Mouse -- Chapter 11: The Genetics of Mouse Models of Systemic Lupus -- Chapter 12: Inhibitory Receptors and Autoimmunity in the Mouse -- Chapter 13: Mouse Models of Immunodeficiency -- Chapter 14: Mouse Models to Study the Pathogenesis of Allergic Asthma -- Chapter 15: The Mouse Trap: How Well Do Mice Model Human Immunology? -- Index -- Cumulative Index -- Last Page. | |
| 520 | |a Immunology, the fourth volume in the four volume set, The Mouse in Biomedical Research, is a completely new addition to this series, dedicated to mouse immunology. It is based on the vast body of knowledge which has made the mouse the model of choice when studying immunity in man. Arguably more is known about the immune system in mice than any other species except man. In large part this is due to the power of genetic engineering to delineate molecular mechanisms. In this volume we present an Overview to mouse immunology, including both the innate and adaptive immune systems, followed by 15 chapters, each dealing with a specific area of immunology in the mouse. These chapters illustrate the power of genetic engineering in dissecting each component of the immune response from the development of lymphoid tissues to signal transduction pathways in activated cells. | ||
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| 700 | 1 | |a Fox, James G. | |
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| contents | Cover -- Copyright page -- Table of Contents -- List of Reviewers for Chapters in this Volume -- Contributors -- Foreword for Volume IV -- Preface -- Overview: Overview of Immunology in the Mouse: Molecular and Cellular Immunology -- Chapter 1: The Molecular Basis of Lymphoid Architecture in the Mouse -- Chapter 2: The Biology of Toll-Like Receptors in Mice -- Chapter 3: Genomic Organization of the Mouse Major Histocompatibility Complex -- Chapter 4: Some Biological Features of Dendritic Cells in the Mouse -- Chapter 5: Mouse Models Revealed the Mechanisms for Somatic Hypermutation and Class Switch Recombination of Immunoglobulin Genes -- Chapter 6: Mouse Natural Killer Cells: Function and Activation -- Chapter 7: Cytokine-Activated JAK-STAT Signaling in the Mouse Immune System -- Chapter 8: Signal Transduction Events Regulating Integrin Function and T Cell Migration in the Mouse -- Chapter 9: Mouse Models of Negative Selection -- Chapter 10: Peripheral Tolerance of T Cells in the Mouse -- Chapter 11: The Genetics of Mouse Models of Systemic Lupus -- Chapter 12: Inhibitory Receptors and Autoimmunity in the Mouse -- Chapter 13: Mouse Models of Immunodeficiency -- Chapter 14: Mouse Models to Study the Pathogenesis of Allergic Asthma -- Chapter 15: The Mouse Trap: How Well Do Mice Model Human Immunology? -- Index -- Cumulative Index -- Last Page. |
| ctrlnum | (OCoLC)85857995 |
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| discipline | Medizin |
| edition | 2nd ed. |
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| indexdate | 2024-11-27T13:16:01Z |
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| language | English |
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| series2 | American College of Laboratory Animal Medicine series |
| spelling | The Mouse in biomedical research. Volume IV : Immunology / edited by James G. Fox [and others]. Immunology 2nd ed. Amsterdam ; Boston : Academic Press, ©2007. 1 online resource (1 volume (xvi, 374 pages)) : illustrations (some color) text txt rdacontent computer c rdamedia online resource cr rdacarrier American College of Laboratory Animal Medicine series Includes bibliographical references and indexes. Print version record. Cover -- Copyright page -- Table of Contents -- List of Reviewers for Chapters in this Volume -- Contributors -- Foreword for Volume IV -- Preface -- Overview: Overview of Immunology in the Mouse: Molecular and Cellular Immunology -- Chapter 1: The Molecular Basis of Lymphoid Architecture in the Mouse -- Chapter 2: The Biology of Toll-Like Receptors in Mice -- Chapter 3: Genomic Organization of the Mouse Major Histocompatibility Complex -- Chapter 4: Some Biological Features of Dendritic Cells in the Mouse -- Chapter 5: Mouse Models Revealed the Mechanisms for Somatic Hypermutation and Class Switch Recombination of Immunoglobulin Genes -- Chapter 6: Mouse Natural Killer Cells: Function and Activation -- Chapter 7: Cytokine-Activated JAK-STAT Signaling in the Mouse Immune System -- Chapter 8: Signal Transduction Events Regulating Integrin Function and T Cell Migration in the Mouse -- Chapter 9: Mouse Models of Negative Selection -- Chapter 10: Peripheral Tolerance of T Cells in the Mouse -- Chapter 11: The Genetics of Mouse Models of Systemic Lupus -- Chapter 12: Inhibitory Receptors and Autoimmunity in the Mouse -- Chapter 13: Mouse Models of Immunodeficiency -- Chapter 14: Mouse Models to Study the Pathogenesis of Allergic Asthma -- Chapter 15: The Mouse Trap: How Well Do Mice Model Human Immunology? -- Index -- Cumulative Index -- Last Page. Immunology, the fourth volume in the four volume set, The Mouse in Biomedical Research, is a completely new addition to this series, dedicated to mouse immunology. It is based on the vast body of knowledge which has made the mouse the model of choice when studying immunity in man. Arguably more is known about the immune system in mice than any other species except man. In large part this is due to the power of genetic engineering to delineate molecular mechanisms. In this volume we present an Overview to mouse immunology, including both the innate and adaptive immune systems, followed by 15 chapters, each dealing with a specific area of immunology in the mouse. These chapters illustrate the power of genetic engineering in dissecting each component of the immune response from the development of lymphoid tissues to signal transduction pathways in activated cells. Mice as laboratory animals. http://id.loc.gov/authorities/subjects/sh85084676 Animal models in research. http://id.loc.gov/authorities/subjects/sh85005212 Laboratory animals. http://id.loc.gov/authorities/subjects/sh85073746 Mice. http://id.loc.gov/authorities/subjects/sh85084671 Diseases Animal models. http://id.loc.gov/authorities/subjects/sh85038412 Animals, Laboratory Mice Biomedical Research Disease Models, Animal Models, Genetic Souris (Animal de laboratoire) Modèles animaux dans la recherche. Animaux de laboratoire. Souris. Maladies Modèles animaux. MEDICAL Immunology. bisacsh Mice fast Laboratory animals fast Diseases Animal models fast Animal models in research fast Mice as laboratory animals fast Fox, James G. has work: The Mouse in biomedical research History, genetics, and wild mice Vol. 1 (Text) https://id.oclc.org/worldcat/entity/E39PCGgk7Jxbg4xPr9fRmVJX7d https://id.oclc.org/worldcat/ontology/hasWork Print version: Mouse in biomedical research. Volume IV. 2nd ed. Amsterdam ; Boston : Academic Press, ©2007 9780123694584 (OCoLC)85857971 American College of Laboratory Animal Medicine series. http://id.loc.gov/authorities/names/n42001771 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=186059 Volltext |
| spellingShingle | The Mouse in biomedical research. Immunology / American College of Laboratory Animal Medicine series. Cover -- Copyright page -- Table of Contents -- List of Reviewers for Chapters in this Volume -- Contributors -- Foreword for Volume IV -- Preface -- Overview: Overview of Immunology in the Mouse: Molecular and Cellular Immunology -- Chapter 1: The Molecular Basis of Lymphoid Architecture in the Mouse -- Chapter 2: The Biology of Toll-Like Receptors in Mice -- Chapter 3: Genomic Organization of the Mouse Major Histocompatibility Complex -- Chapter 4: Some Biological Features of Dendritic Cells in the Mouse -- Chapter 5: Mouse Models Revealed the Mechanisms for Somatic Hypermutation and Class Switch Recombination of Immunoglobulin Genes -- Chapter 6: Mouse Natural Killer Cells: Function and Activation -- Chapter 7: Cytokine-Activated JAK-STAT Signaling in the Mouse Immune System -- Chapter 8: Signal Transduction Events Regulating Integrin Function and T Cell Migration in the Mouse -- Chapter 9: Mouse Models of Negative Selection -- Chapter 10: Peripheral Tolerance of T Cells in the Mouse -- Chapter 11: The Genetics of Mouse Models of Systemic Lupus -- Chapter 12: Inhibitory Receptors and Autoimmunity in the Mouse -- Chapter 13: Mouse Models of Immunodeficiency -- Chapter 14: Mouse Models to Study the Pathogenesis of Allergic Asthma -- Chapter 15: The Mouse Trap: How Well Do Mice Model Human Immunology? -- Index -- Cumulative Index -- Last Page. Mice as laboratory animals. http://id.loc.gov/authorities/subjects/sh85084676 Animal models in research. http://id.loc.gov/authorities/subjects/sh85005212 Laboratory animals. http://id.loc.gov/authorities/subjects/sh85073746 Mice. http://id.loc.gov/authorities/subjects/sh85084671 Diseases Animal models. http://id.loc.gov/authorities/subjects/sh85038412 Animals, Laboratory Mice Biomedical Research Disease Models, Animal Models, Genetic Souris (Animal de laboratoire) Modèles animaux dans la recherche. Animaux de laboratoire. Souris. Maladies Modèles animaux. MEDICAL Immunology. bisacsh Mice fast Laboratory animals fast Diseases Animal models fast Animal models in research fast Mice as laboratory animals fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85084676 http://id.loc.gov/authorities/subjects/sh85005212 http://id.loc.gov/authorities/subjects/sh85073746 http://id.loc.gov/authorities/subjects/sh85084671 http://id.loc.gov/authorities/subjects/sh85038412 |
| title | The Mouse in biomedical research. Immunology / |
| title_alt | Immunology |
| title_auth | The Mouse in biomedical research. Immunology / |
| title_exact_search | The Mouse in biomedical research. Immunology / |
| title_full | The Mouse in biomedical research. Volume IV : Immunology / edited by James G. Fox [and others]. |
| title_fullStr | The Mouse in biomedical research. Volume IV : Immunology / edited by James G. Fox [and others]. |
| title_full_unstemmed | The Mouse in biomedical research. Volume IV : Immunology / edited by James G. Fox [and others]. |
| title_short | The Mouse in biomedical research. |
| title_sort | mouse in biomedical research immunology |
| title_sub | Immunology / |
| topic | Mice as laboratory animals. http://id.loc.gov/authorities/subjects/sh85084676 Animal models in research. http://id.loc.gov/authorities/subjects/sh85005212 Laboratory animals. http://id.loc.gov/authorities/subjects/sh85073746 Mice. http://id.loc.gov/authorities/subjects/sh85084671 Diseases Animal models. http://id.loc.gov/authorities/subjects/sh85038412 Animals, Laboratory Mice Biomedical Research Disease Models, Animal Models, Genetic Souris (Animal de laboratoire) Modèles animaux dans la recherche. Animaux de laboratoire. Souris. Maladies Modèles animaux. MEDICAL Immunology. bisacsh Mice fast Laboratory animals fast Diseases Animal models fast Animal models in research fast Mice as laboratory animals fast |
| topic_facet | Mice as laboratory animals. Animal models in research. Laboratory animals. Mice. Diseases Animal models. Animals, Laboratory Mice Biomedical Research Disease Models, Animal Models, Genetic Souris (Animal de laboratoire) Modèles animaux dans la recherche. Animaux de laboratoire. Souris. Maladies Modèles animaux. MEDICAL Immunology. Laboratory animals Diseases Animal models Animal models in research Mice as laboratory animals |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=186059 |
| work_keys_str_mv | AT foxjamesg themouseinbiomedicalresearchvolumeivimmunology AT foxjamesg immunology AT foxjamesg mouseinbiomedicalresearchvolumeivimmunology |