Gene regulation and metabolism :: postgenomic computational approaches /
As exciting as the new field of genomics is, it has not yet produced a basic conceptual change in biology. The fundamental problems remain: the origin of life, cell organization, the pathways of differentiation, aging, and the molecular and cellular capabilities of the brain. What has occurred is an...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge, Mass. :
MIT Press,
©2002.
|
| Schriftenreihe: | Computational molecular biology.
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | As exciting as the new field of genomics is, it has not yet produced a basic conceptual change in biology. The fundamental problems remain: the origin of life, cell organization, the pathways of differentiation, aging, and the molecular and cellular capabilities of the brain. What has occurred is an explosion of molecular information obtained by genomic sequences, which will soon be followed by exhaustive catalogs of protein interactions and protein function. This wealth of information can be analyzed and manipulated only with the help of computers. The rapidly expanding role of computers in biology may usher in a profound conceptual change in how we study living systems in the laboratory. This book focuses on current computational approaches to understanding the complex networks of metabolic and gene regulatory capabilities of the cell. The contributors look well beyond the state of the art in computational biology to anticipate what biological research will be like in a post-genomic world. |
| Beschreibung: | 1 online resource (x, 310 pages) : illustrations |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9780262270649 0262270641 0585436916 9780585436913 9780262032971 026203297X |
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| 245 | 0 | 0 | |a Gene regulation and metabolism : |b postgenomic computational approaches / |c edited by Julio Collado-Vides and Ralf Hofestädt. |
| 260 | |a Cambridge, Mass. : |b MIT Press, |c ©2002. | ||
| 300 | |a 1 online resource (x, 310 pages) : |b illustrations | ||
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| 505 | 0 | |a Are the eyes homologous? -- Automation of protein sequence characterization and its application in whole proteome analysis -- Information fusion and metabolic network control -- Specificity of protein-DNA interactions -- Genomics of gene regulation: the view from Escherichia coli -- Discovery of DNA regulatory motifs -- Gene networks description and modeling in the GeneNet system -- Regulation of cellular states in mammalian cells from a genomewide view -- Predicting protein function and networks on a genomewide scale -- Metabolic pathways -- Toward computer simulation of the whole cell. | |
| 588 | 0 | |a Print version record. | |
| 520 | |a As exciting as the new field of genomics is, it has not yet produced a basic conceptual change in biology. The fundamental problems remain: the origin of life, cell organization, the pathways of differentiation, aging, and the molecular and cellular capabilities of the brain. What has occurred is an explosion of molecular information obtained by genomic sequences, which will soon be followed by exhaustive catalogs of protein interactions and protein function. This wealth of information can be analyzed and manipulated only with the help of computers. The rapidly expanding role of computers in biology may usher in a profound conceptual change in how we study living systems in the laboratory. This book focuses on current computational approaches to understanding the complex networks of metabolic and gene regulatory capabilities of the cell. The contributors look well beyond the state of the art in computational biology to anticipate what biological research will be like in a post-genomic world. | ||
| 546 | |a English. | ||
| 650 | 0 | |a Genetics |x Mathematical models. |0 http://id.loc.gov/authorities/subjects/sh85053879 | |
| 650 | 0 | |a Molecular biology |x Mathematical models. | |
| 650 | 0 | |a Genetic regulation. |0 http://id.loc.gov/authorities/subjects/sh85053870 | |
| 650 | 0 | |a Metabolism. |0 http://id.loc.gov/authorities/subjects/sh85084013 | |
| 650 | 1 | 2 | |a Models, Genetic |
| 650 | 2 | 2 | |a Gene Expression Regulation |
| 650 | 2 | 2 | |a Metabolism |
| 650 | 6 | |a Biologie moléculaire |x Modèles mathématiques. | |
| 650 | 6 | |a Régulation génétique. | |
| 650 | 6 | |a Métabolisme. | |
| 650 | 7 | |a metabolism (biological concept) |2 aat | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Molecular Biology. |2 bisacsh | |
| 650 | 7 | |a Metabolism |2 fast | |
| 650 | 7 | |a Genetic regulation |2 fast | |
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| 653 | |a BIOMEDICAL SCIENCES/Quantitative Biology | ||
| 700 | 1 | |a Collado-Vides, Julio. | |
| 700 | 1 | |a Hofestädt, Ralf. | |
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Datensatz im Suchindex
| DE-BY-FWS_katkey | ZDB-4-EBA-ocm51959878 |
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| _version_ | 1816881605768118272 |
| adam_text | |
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| author2 | Collado-Vides, Julio Hofestädt, Ralf |
| author2_role | |
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| contents | Are the eyes homologous? -- Automation of protein sequence characterization and its application in whole proteome analysis -- Information fusion and metabolic network control -- Specificity of protein-DNA interactions -- Genomics of gene regulation: the view from Escherichia coli -- Discovery of DNA regulatory motifs -- Gene networks description and modeling in the GeneNet system -- Regulation of cellular states in mammalian cells from a genomewide view -- Predicting protein function and networks on a genomewide scale -- Metabolic pathways -- Toward computer simulation of the whole cell. |
| ctrlnum | (OCoLC)51959878 |
| dewey-full | 572.8/01/5118 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572.8/01/5118 |
| dewey-search | 572.8/01/5118 |
| dewey-sort | 3572.8 11 45118 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Electronic eBook |
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| id | ZDB-4-EBA-ocm51959878 |
| illustrated | Illustrated |
| indexdate | 2024-11-27T13:15:23Z |
| institution | BVB |
| isbn | 9780262270649 0262270641 0585436916 9780585436913 9780262032971 026203297X |
| language | English |
| oclc_num | 51959878 |
| open_access_boolean | |
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| owner_facet | MAIN DE-863 DE-BY-FWS |
| physical | 1 online resource (x, 310 pages) : illustrations |
| psigel | ZDB-4-EBA |
| publishDate | 2002 |
| publishDateSearch | 2002 |
| publishDateSort | 2002 |
| publisher | MIT Press, |
| record_format | marc |
| series | Computational molecular biology. |
| series2 | Computational molecular biology |
| spelling | Gene regulation and metabolism : postgenomic computational approaches / edited by Julio Collado-Vides and Ralf Hofestädt. Cambridge, Mass. : MIT Press, ©2002. 1 online resource (x, 310 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier text file rdaft Computational molecular biology Includes bibliographical references and index. Are the eyes homologous? -- Automation of protein sequence characterization and its application in whole proteome analysis -- Information fusion and metabolic network control -- Specificity of protein-DNA interactions -- Genomics of gene regulation: the view from Escherichia coli -- Discovery of DNA regulatory motifs -- Gene networks description and modeling in the GeneNet system -- Regulation of cellular states in mammalian cells from a genomewide view -- Predicting protein function and networks on a genomewide scale -- Metabolic pathways -- Toward computer simulation of the whole cell. Print version record. As exciting as the new field of genomics is, it has not yet produced a basic conceptual change in biology. The fundamental problems remain: the origin of life, cell organization, the pathways of differentiation, aging, and the molecular and cellular capabilities of the brain. What has occurred is an explosion of molecular information obtained by genomic sequences, which will soon be followed by exhaustive catalogs of protein interactions and protein function. This wealth of information can be analyzed and manipulated only with the help of computers. The rapidly expanding role of computers in biology may usher in a profound conceptual change in how we study living systems in the laboratory. This book focuses on current computational approaches to understanding the complex networks of metabolic and gene regulatory capabilities of the cell. The contributors look well beyond the state of the art in computational biology to anticipate what biological research will be like in a post-genomic world. English. Genetics Mathematical models. http://id.loc.gov/authorities/subjects/sh85053879 Molecular biology Mathematical models. Genetic regulation. http://id.loc.gov/authorities/subjects/sh85053870 Metabolism. http://id.loc.gov/authorities/subjects/sh85084013 Models, Genetic Gene Expression Regulation Metabolism Biologie moléculaire Modèles mathématiques. Régulation génétique. Métabolisme. metabolism (biological concept) aat SCIENCE Life Sciences Molecular Biology. bisacsh Metabolism fast Genetic regulation fast Genetics Mathematical models fast Molecular biology Mathematical models fast BIOMEDICAL SCIENCES/Quantitative Biology Collado-Vides, Julio. Hofestädt, Ralf. has work: Gene regulation and metabolism (Text) https://id.oclc.org/worldcat/entity/E39PD3gb4yrdWQDTBB9KVW3ytX https://id.oclc.org/worldcat/ontology/hasWork Print version: Gene regulation and metabolism. Cambridge, Mass. : MIT Press, ©2002 026203297X (DLC) 2001056247 (OCoLC)48383628 Computational molecular biology. http://id.loc.gov/authorities/names/no2001017947 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=75010 Volltext |
| spellingShingle | Gene regulation and metabolism : postgenomic computational approaches / Computational molecular biology. Are the eyes homologous? -- Automation of protein sequence characterization and its application in whole proteome analysis -- Information fusion and metabolic network control -- Specificity of protein-DNA interactions -- Genomics of gene regulation: the view from Escherichia coli -- Discovery of DNA regulatory motifs -- Gene networks description and modeling in the GeneNet system -- Regulation of cellular states in mammalian cells from a genomewide view -- Predicting protein function and networks on a genomewide scale -- Metabolic pathways -- Toward computer simulation of the whole cell. Genetics Mathematical models. http://id.loc.gov/authorities/subjects/sh85053879 Molecular biology Mathematical models. Genetic regulation. http://id.loc.gov/authorities/subjects/sh85053870 Metabolism. http://id.loc.gov/authorities/subjects/sh85084013 Models, Genetic Gene Expression Regulation Metabolism Biologie moléculaire Modèles mathématiques. Régulation génétique. Métabolisme. metabolism (biological concept) aat SCIENCE Life Sciences Molecular Biology. bisacsh Metabolism fast Genetic regulation fast Genetics Mathematical models fast Molecular biology Mathematical models fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85053879 http://id.loc.gov/authorities/subjects/sh85053870 http://id.loc.gov/authorities/subjects/sh85084013 |
| title | Gene regulation and metabolism : postgenomic computational approaches / |
| title_auth | Gene regulation and metabolism : postgenomic computational approaches / |
| title_exact_search | Gene regulation and metabolism : postgenomic computational approaches / |
| title_full | Gene regulation and metabolism : postgenomic computational approaches / edited by Julio Collado-Vides and Ralf Hofestädt. |
| title_fullStr | Gene regulation and metabolism : postgenomic computational approaches / edited by Julio Collado-Vides and Ralf Hofestädt. |
| title_full_unstemmed | Gene regulation and metabolism : postgenomic computational approaches / edited by Julio Collado-Vides and Ralf Hofestädt. |
| title_short | Gene regulation and metabolism : |
| title_sort | gene regulation and metabolism postgenomic computational approaches |
| title_sub | postgenomic computational approaches / |
| topic | Genetics Mathematical models. http://id.loc.gov/authorities/subjects/sh85053879 Molecular biology Mathematical models. Genetic regulation. http://id.loc.gov/authorities/subjects/sh85053870 Metabolism. http://id.loc.gov/authorities/subjects/sh85084013 Models, Genetic Gene Expression Regulation Metabolism Biologie moléculaire Modèles mathématiques. Régulation génétique. Métabolisme. metabolism (biological concept) aat SCIENCE Life Sciences Molecular Biology. bisacsh Metabolism fast Genetic regulation fast Genetics Mathematical models fast Molecular biology Mathematical models fast |
| topic_facet | Genetics Mathematical models. Molecular biology Mathematical models. Genetic regulation. Metabolism. Models, Genetic Gene Expression Regulation Metabolism Biologie moléculaire Modèles mathématiques. Régulation génétique. Métabolisme. metabolism (biological concept) SCIENCE Life Sciences Molecular Biology. Genetic regulation Genetics Mathematical models Molecular biology Mathematical models |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=75010 |
| work_keys_str_mv | AT colladovidesjulio generegulationandmetabolismpostgenomiccomputationalapproaches AT hofestadtralf generegulationandmetabolismpostgenomiccomputationalapproaches |