Integrative approaches to molecular biology /:
What are the main challenges of computational molecular biology once the genome projects are completed? Integrative Approaches to Molecular Biology focuses on molecular biology beyond sequences: from gene regulation to differentiation, a higher-level integration that will be a major theme in biology...
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| Weitere Verfasser: | , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge, Mass. :
MIT Press,
©1996.
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | What are the main challenges of computational molecular biology once the genome projects are completed? Integrative Approaches to Molecular Biology focuses on molecular biology beyond sequences: from gene regulation to differentiation, a higher-level integration that will be a major theme in biology following conclusion of the genome program. It charts the course of the emerging discipline of integrative molecular biology from macromolecular sequences to a biological (and theoretical) perspective, showing that novel integrative methodologies and paradigms are emerging at the confluence of such disciplines as computer science, logic, linguistics, and mathematics. Following an introductory chapter by Richard Lewontin that offers a critique of the evolutionary process as one of engineering design, the first part of the book, on computational biology, addresses issues concerning protein and DNA sequences within genome projects and a federated infrastructure for databases. The second part brings together experimental, evolutionary, computational, and theoretical approaches dealing with regulation of gene expression, metabolic pathways, and cell differentiation. The book concludes with a chapter on problems and perspectives on artificial intelligence. |
| Beschreibung: | Consequence of a meeting held at the Center for Nitrogen Fixation, National Autonomous University of Mexico, Cuernavaca, in Feb. 1994. |
| Beschreibung: | 1 online resource (x, 345 pages) : illustrations |
| Bibliographie: | Includes bibliographical references (pages 303-330) and index. |
| ISBN: | 0585341044 9780585341040 026227065X 9780262270656 |
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| 504 | |a Includes bibliographical references (pages 303-330) and index. | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Evolution as engineering / Richard C. Lewontin -- Analysis of bacteriophage T4 based on the completed DNA sequence / Elizabeth Kutter -- The identification of protein functional patterns / Temple F. Smith, Richard Lathrop, and Fred E. Cohen -- Comparative genomics : a new integrative biology / Robert J. Robbins -- On genomes and cosmologies / Antoine Danchin -- A kinetic formalism for integrative molecular biology : manifestation in biochemical systems theory and use in elucidating design principles for gene circuits / Michael A. Savageau -- Genome analysis and global regulation in Escherichia coli / Frederick C. Neidhardt -- Feedback loops : the wheels of regulatory networks / René Thomas -- Integrative representations of the regulation of gene expression / Julio Collado-Vides -- Eukaryotic transcription / Thomas Oehler and Leonard Guarente -- Analysis of complex metabolic pathways / Michael L. Mavrovouniotis -- Where do biochemical pathways lead? / Jack Cohen and Sean H. Rice -- Gene circuits and their uses / John Reinitz and David H. Sharp -- Fallback positions and fossils in gene regulation / Boris Magasanik -- The language of the genes / Robert C. Berwick. | |
| 520 | |a What are the main challenges of computational molecular biology once the genome projects are completed? Integrative Approaches to Molecular Biology focuses on molecular biology beyond sequences: from gene regulation to differentiation, a higher-level integration that will be a major theme in biology following conclusion of the genome program. It charts the course of the emerging discipline of integrative molecular biology from macromolecular sequences to a biological (and theoretical) perspective, showing that novel integrative methodologies and paradigms are emerging at the confluence of such disciplines as computer science, logic, linguistics, and mathematics. Following an introductory chapter by Richard Lewontin that offers a critique of the evolutionary process as one of engineering design, the first part of the book, on computational biology, addresses issues concerning protein and DNA sequences within genome projects and a federated infrastructure for databases. The second part brings together experimental, evolutionary, computational, and theoretical approaches dealing with regulation of gene expression, metabolic pathways, and cell differentiation. The book concludes with a chapter on problems and perspectives on artificial intelligence. | ||
| 546 | |a English. | ||
| 650 | 0 | |a Molecular biology |v Congresses. | |
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| 700 | 1 | |a Smith, Temple. | |
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| 776 | 0 | 8 | |i Print version: |t Integrative approaches to molecular biology. |d Cambridge, Mass. : MIT Press, ©1996 |z 0262032392 |
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| author2 | Collado-Vides, Julio Magasanik, Boris Smith, Temple |
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| contents | Evolution as engineering / Richard C. Lewontin -- Analysis of bacteriophage T4 based on the completed DNA sequence / Elizabeth Kutter -- The identification of protein functional patterns / Temple F. Smith, Richard Lathrop, and Fred E. Cohen -- Comparative genomics : a new integrative biology / Robert J. Robbins -- On genomes and cosmologies / Antoine Danchin -- A kinetic formalism for integrative molecular biology : manifestation in biochemical systems theory and use in elucidating design principles for gene circuits / Michael A. Savageau -- Genome analysis and global regulation in Escherichia coli / Frederick C. Neidhardt -- Feedback loops : the wheels of regulatory networks / René Thomas -- Integrative representations of the regulation of gene expression / Julio Collado-Vides -- Eukaryotic transcription / Thomas Oehler and Leonard Guarente -- Analysis of complex metabolic pathways / Michael L. Mavrovouniotis -- Where do biochemical pathways lead? / Jack Cohen and Sean H. Rice -- Gene circuits and their uses / John Reinitz and David H. Sharp -- Fallback positions and fossils in gene regulation / Boris Magasanik -- The language of the genes / Robert C. Berwick. |
| ctrlnum | (OCoLC)47011581 |
| dewey-full | 574.8/8 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 574 - [Unassigned] |
| dewey-raw | 574.8/8 |
| dewey-search | 574.8/8 |
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| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Electronic eBook |
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| genre | Congress proceedings (reports) aat Conference papers and proceedings fast Conference papers and proceedings. lcgft http://id.loc.gov/authorities/genreForms/gf2014026068 Actes de congrès. rvmgf |
| genre_facet | Congress proceedings (reports) Conference papers and proceedings Conference papers and proceedings. Actes de congrès. |
| id | ZDB-4-EBA-ocm47011581 |
| illustrated | Illustrated |
| indexdate | 2024-11-27T13:15:14Z |
| institution | BVB |
| isbn | 0585341044 9780585341040 026227065X 9780262270656 |
| language | English |
| oclc_num | 47011581 |
| open_access_boolean | |
| owner | MAIN DE-863 DE-BY-FWS |
| owner_facet | MAIN DE-863 DE-BY-FWS |
| physical | 1 online resource (x, 345 pages) : illustrations |
| psigel | ZDB-4-EBA |
| publishDate | 1996 |
| publishDateSearch | 1996 |
| publishDateSort | 1996 |
| publisher | MIT Press, |
| record_format | marc |
| spelling | Integrative approaches to molecular biology / edited by Julio Collado-Vides, Boris Magasanik, and Temple F. Smith. Cambridge, Mass. : MIT Press, ©1996. 1 online resource (x, 345 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier Consequence of a meeting held at the Center for Nitrogen Fixation, National Autonomous University of Mexico, Cuernavaca, in Feb. 1994. Includes bibliographical references (pages 303-330) and index. Print version record. Evolution as engineering / Richard C. Lewontin -- Analysis of bacteriophage T4 based on the completed DNA sequence / Elizabeth Kutter -- The identification of protein functional patterns / Temple F. Smith, Richard Lathrop, and Fred E. Cohen -- Comparative genomics : a new integrative biology / Robert J. Robbins -- On genomes and cosmologies / Antoine Danchin -- A kinetic formalism for integrative molecular biology : manifestation in biochemical systems theory and use in elucidating design principles for gene circuits / Michael A. Savageau -- Genome analysis and global regulation in Escherichia coli / Frederick C. Neidhardt -- Feedback loops : the wheels of regulatory networks / René Thomas -- Integrative representations of the regulation of gene expression / Julio Collado-Vides -- Eukaryotic transcription / Thomas Oehler and Leonard Guarente -- Analysis of complex metabolic pathways / Michael L. Mavrovouniotis -- Where do biochemical pathways lead? / Jack Cohen and Sean H. Rice -- Gene circuits and their uses / John Reinitz and David H. Sharp -- Fallback positions and fossils in gene regulation / Boris Magasanik -- The language of the genes / Robert C. Berwick. What are the main challenges of computational molecular biology once the genome projects are completed? Integrative Approaches to Molecular Biology focuses on molecular biology beyond sequences: from gene regulation to differentiation, a higher-level integration that will be a major theme in biology following conclusion of the genome program. It charts the course of the emerging discipline of integrative molecular biology from macromolecular sequences to a biological (and theoretical) perspective, showing that novel integrative methodologies and paradigms are emerging at the confluence of such disciplines as computer science, logic, linguistics, and mathematics. Following an introductory chapter by Richard Lewontin that offers a critique of the evolutionary process as one of engineering design, the first part of the book, on computational biology, addresses issues concerning protein and DNA sequences within genome projects and a federated infrastructure for databases. The second part brings together experimental, evolutionary, computational, and theoretical approaches dealing with regulation of gene expression, metabolic pathways, and cell differentiation. The book concludes with a chapter on problems and perspectives on artificial intelligence. English. Molecular biology Congresses. Molecular Biology Biologie moléculaire Congrès. SCIENCE Life Sciences Molecular Biology. bisacsh Molecular biology fast Molekularbiologie gnd http://d-nb.info/gnd/4039983-7 Kongress gnd http://d-nb.info/gnd/4130470-6 Moleculaire biologie. gtt Molecular biology Congress proceedings (reports) aat Conference papers and proceedings fast Conference papers and proceedings. lcgft http://id.loc.gov/authorities/genreForms/gf2014026068 Actes de congrès. rvmgf Collado-Vides, Julio. Magasanik, Boris. Smith, Temple. has work: Integrative approaches to molecular biology (Text) https://id.oclc.org/worldcat/entity/E39PCH4q4QBRQ8d7RTbtKr7wkC https://id.oclc.org/worldcat/ontology/hasWork Print version: Integrative approaches to molecular biology. Cambridge, Mass. : MIT Press, ©1996 0262032392 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=48796 Volltext |
| spellingShingle | Integrative approaches to molecular biology / Evolution as engineering / Richard C. Lewontin -- Analysis of bacteriophage T4 based on the completed DNA sequence / Elizabeth Kutter -- The identification of protein functional patterns / Temple F. Smith, Richard Lathrop, and Fred E. Cohen -- Comparative genomics : a new integrative biology / Robert J. Robbins -- On genomes and cosmologies / Antoine Danchin -- A kinetic formalism for integrative molecular biology : manifestation in biochemical systems theory and use in elucidating design principles for gene circuits / Michael A. Savageau -- Genome analysis and global regulation in Escherichia coli / Frederick C. Neidhardt -- Feedback loops : the wheels of regulatory networks / René Thomas -- Integrative representations of the regulation of gene expression / Julio Collado-Vides -- Eukaryotic transcription / Thomas Oehler and Leonard Guarente -- Analysis of complex metabolic pathways / Michael L. Mavrovouniotis -- Where do biochemical pathways lead? / Jack Cohen and Sean H. Rice -- Gene circuits and their uses / John Reinitz and David H. Sharp -- Fallback positions and fossils in gene regulation / Boris Magasanik -- The language of the genes / Robert C. Berwick. Molecular biology Congresses. Molecular Biology Biologie moléculaire Congrès. SCIENCE Life Sciences Molecular Biology. bisacsh Molecular biology fast Molekularbiologie gnd http://d-nb.info/gnd/4039983-7 Kongress gnd http://d-nb.info/gnd/4130470-6 Moleculaire biologie. gtt |
| subject_GND | http://d-nb.info/gnd/4039983-7 http://d-nb.info/gnd/4130470-6 http://id.loc.gov/authorities/genreForms/gf2014026068 |
| title | Integrative approaches to molecular biology / |
| title_auth | Integrative approaches to molecular biology / |
| title_exact_search | Integrative approaches to molecular biology / |
| title_full | Integrative approaches to molecular biology / edited by Julio Collado-Vides, Boris Magasanik, and Temple F. Smith. |
| title_fullStr | Integrative approaches to molecular biology / edited by Julio Collado-Vides, Boris Magasanik, and Temple F. Smith. |
| title_full_unstemmed | Integrative approaches to molecular biology / edited by Julio Collado-Vides, Boris Magasanik, and Temple F. Smith. |
| title_short | Integrative approaches to molecular biology / |
| title_sort | integrative approaches to molecular biology |
| topic | Molecular biology Congresses. Molecular Biology Biologie moléculaire Congrès. SCIENCE Life Sciences Molecular Biology. bisacsh Molecular biology fast Molekularbiologie gnd http://d-nb.info/gnd/4039983-7 Kongress gnd http://d-nb.info/gnd/4130470-6 Moleculaire biologie. gtt |
| topic_facet | Molecular biology Congresses. Molecular Biology Biologie moléculaire Congrès. SCIENCE Life Sciences Molecular Biology. Molecular biology Molekularbiologie Kongress Moleculaire biologie. Congress proceedings (reports) Conference papers and proceedings Conference papers and proceedings. Actes de congrès. |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=48796 |
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