Verfügbarkeit: Medically assisted conception :

Medically assisted conception :: an agenda for research : report of a study /

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Bibliographische Detailangaben
Körperschaften:	Committee on the Basic Science Foundations of Medically Assisted Conception, Institute of Medicine (U.S.). Division of Health Sciences Policy, National Research Council (U.S.). Board on Agriculture
Weitere Verfasser:	Ryan, Kenneth J., 1926-2002
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	Washington, D.C. : National Academy Press, 1989.
Schriftenreihe:	IOM publication ; 89-008.
Schlagworte:	Fertilization in vitro. Fertilization in vitro, Human. Reproductive technology. Artificial insemination. Human reproductive technology. Embryo transplantation. Research. Risk. Risk assessment. Agriculture. Animal experimentation. Contraception. Federal government. Goal (Psychology) Political science. Politics, Practical. Infertility. International cooperation. Methodology. Sex preselection. Social control. Embryo Transfer Fertilization in Vitro Embryo Research Embryo, Mammalian Research Risk Risk Assessment Technology Assessment, Biomedical Insemination, Artificial Reproductive Techniques, Assisted Reproductive Techniques Agriculture Animal Experimentation Animal Welfare Biomedical Research Contraception Federal Government Financial Support Goals Government Government Regulation Infertility International Cooperation Internationality Methods Public Policy Sex Preselection Social Control, Formal Fécondation in vitro. Reproduction > Innovations. Insémination artificielle. Procréation médicalement assistée. Embryons > Transplantation. Recherche. Risque. Évaluation du risque. Expérimentation animale. Gouvernement fédéral. But (Psychologie) Institutions politiques. Infertilité. Coopération internationale. Méthodologie. Sexe des enfants > Choix. Contrôle social. research (function) risk assessment. farming (activity or system) federal government. governments (administrative bodies) methodology. agriculture (discipline) HEALTH & FITNESS > Infertility. Social control Sex preselection Risk assessment Politics, Practical Political science Methodology International cooperation Federal government Embryo transplantation Animal experimentation Artificial insemination Fertilization in vitro Fertilization in vitro, Human Human reproductive technology Reproductive technology United States
Online-Zugang:	Volltext
Beschreibung:	Report prepared by the Committee on the Basic Science Foundation of Medically Assisted Conception. Committee chairman: Kenneth J. Ryan. " ... project received support from the National Academy of Sciences Basic Science Fund and the U.S. Department of Agriculture (contract 59-32U4-8-63/R)." On cover: Report of a study and workshop papers.
Beschreibung:	1 online resource (viii, 361 pages) : illustrations
Format:	Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Bibliographie:	Includes bibliographical references.
ISBN:	0585154163 9780585154169 9780309559836 0309559839 1280214287 9781280214288 9786610214280 661021428X

Internformat

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245	1	0	\|a Medically assisted conception : \|b an agenda for research : report of a study / \|c by a committee of the Institute of Medicine, Division of Health Sciences Policy, National Research Council, Board on Agriculture.
260			\|a Washington, D.C. : \|b National Academy Press, \|c 1989.
300			\|a 1 online resource (viii, 361 pages) : \|b illustrations
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490	1		\|a IOM ; \|v 89-08
500			\|a Report prepared by the Committee on the Basic Science Foundation of Medically Assisted Conception.
500			\|a Committee chairman: Kenneth J. Ryan.
500			\|a " ... project received support from the National Academy of Sciences Basic Science Fund and the U.S. Department of Agriculture (contract 59-32U4-8-63/R)."
500			\|a On cover: Report of a study and workshop papers.
504			\|a Includes bibliographical references.
588	0		\|a Print version record.
506			\|3 Use copy \|f Restrictions unspecified \|2 star \|5 MiAaHDL
533			\|a Electronic reproduction. \|b [Place of publication not identified] : \|c HathiTrust Digital Library, \|d 2010. \|5 MiAaHDL
538			\|a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. \|u http://purl.oclc.org/DLF/benchrepro0212 \|5 MiAaHDL
583	1		\|a digitized \|c 2010 \|h HathiTrust Digital Library \|l committed to preserve \|2 pda \|5 MiAaHDL
505	0		\|a Medically Assisted Conception -- Copyright -- Contents -- Acknowledgements -- Preface -- SCOPE OF THE STUDY -- Summary -- SOCIAL CONCERNS THAT CAN BE ADDRESSED BY IVFET -- BARRIERS TO PROGRESS IN IN VITRO FERTILIZATION AND EMBRYO TRANSFER -- Ethical And Social Issues -- The Federal Government And Embryo Research -- Domestic And Foreign Decisions Concerning Embryo Research -- Other Barriers To Scientific Progress -- RESEARCH AGENDA -- Basic Science -- Male Gametogenesis -- Female Gametogenesis -- Fertilization -- Preimplantation Development -- Implantation -- Technological Advances -- Clinical Research Opportunities -- CONCLUSIONS AND RECOMMENDATIONS -- Developing Research Policy -- Basic Science Foundations -- Applied Research -- Clinical Research Opportunities -- Improving Communications -- REFERENCES -- Chapter 1 In Vitro Fertilization And Embryo Transfer And Social Concerns -- INFERTILITY -- Treatments For Infertility -- In Vitro Fertilization And Embryo Transfer -- Gamete Intrafallopian Transfer -- Donated Gametes Or Concepti -- CONTRACEPTION -- AGRICULTURE -- BIODIVERSITY -- PRIMATES FOR RESEARCH -- REFERENCES -- Chapter 2 Advances In The Practice And Science Base Of Medical, Assisted Conception -- DEVELOPMENTS IN HUMAN IN VITRO FERTILIZATION [ 1 ] -- DEVELOPMENTS IN ASSISTED CONCEPTION IN FOOD-PRODUCING ANIMALS [ 2 ] -- GAMETOGENESIS AND GAMETES -- Induction Of Gametogenesis And Superovulation [ 3 ] -- Biology And Maturation [ 4 ] -- Intratesticular And Intraovarian Paracrine Control [ 5 ] -- Assessment Of Gametes [ 6 ] -- FERTILIZATION [ 7 ] -- PREIMPLANTATION DEVELOPMENT [ 8 ] -- Metabolic Substrates And Pathways -- Gene Expression In Early Embryonic Development -- Regulative Potential Of Micromanipulated Embryos -- IMPLANTATION [ 9 ] -- ENDNOTES -- Chapter 3 Barriers To Progress In In Vitro Fertilization And Embryo Transfer.
505	8		\|a ETHICAL AND SOCIAL ISSUES -- The Federal Government And Embryo Research -- Domestic And Foreign Decisions On Embryo Research -- OTHER BARRIERS TO SCIENTIFIC PROGRESS -- Deficiencies In The Science Base -- Research Funding -- Lack Of Communication Among Researchers -- Societal Concerns -- Sources Of Research Material -- REFERENCES -- Chapter 4 Research Agenda And Recommendations -- RESEARCH AGENDA -- Basic Science -- Male Gametogenesis -- Female Gametogenesis -- Fertilization -- Preimplantation Development -- Implantation -- Technological Advances -- Clinical Research Opportunities -- CONCLUSIONS AND RECOMMENDATIONS -- Developing Research Policy -- Basic Science Foundations -- Applied Research -- Clinical Research Opportunities -- Improving Communications -- Appendix A Committee On Basic Science Foundations Of Medically Assisted Conception -- TECHNOLOGIES FOR ASSISTED CONCEPTION/EMBRYO TRANSFER IN AGRICULTURAL AND VETERINARY PRACTICE -- Introduction -- Artificial Insemination -- Superovulation -- Embryo Transfer -- Freezing Of Embryos -- Sexing Of Embryos -- Sexing By Y Chromosome Specific Dna Hybridization -- Multiplication Of Embryos -- Nuclear Transfer -- In Vitro Production Of Embryos -- Oocyte Maturation -- In Vitro Fertilization -- Development Of Embryos In Vitro -- Gene Transfer -- Conclusions -- References -- OVARIAN STIMULATION IN NON-HUMAN PRIMATES -- Introduction -- The Menstrual Cycle -- Regulation Of Folliculogenesis -- Ovarian Stimulation -- Problems With Stimulated Ovarian Function -- Solutions For Problems With Stimulated Ovarian Function -- Acknowledgement -- References -- RESPONSES TO GONADOTROPINS IN DOMESTIC ANIMALS -- Introduction -- Superovulation In Domestic Animals -- Superovulation Of Cattle -- Superovulation Of Sheep And Goats -- Effects Of Exogenous Gonadotropins On Horses -- Ovulation Induction In Pigs.
505	8		\|a Recommendations For Future Directions In Research -- Summary -- References -- MEMBRANE MODELS: EVOLUTION FROM THE FLUID-MOSAIC STANDBY ROY HAMMERSTEDT -- Introduction -- Complexity Of The Cell Surface -- Asymmetry Of Cell Surfaces -- Lipid Domains -- Relative Speed Of Membrane Events -- Spatial Relationships On The Membrane Surface -- Summary -- Acknowledgements -- References -- MAMMALIAN OOCYTE MATURATION: MECHANISMS FOR REGULATION AND PROSPECTS FOR PRACTICAL APPLICATION OF IN VITRO TECHNOLOGY -- The Ovarian Follicle As The Support System For Oocyte Development In Vivo -- Identification Of Molecules And Pathways That Participate In The Maintenance Of Meiotic Arrest -- Induction Of Oocyte Maturation -- Similarities Between Mechanisms That Govern Meiotic and Mitotic Cell Division -- Murine Oocyte Growth And Development In Culture -- Prospects For The Practical Utilization Of Oocyte Culture Systems -- Expansion Of Populations Of Rare Or Agriculturally Important Mammals -- Acknowledgments -- References -- INTRAGONADAL CONTROL OF TESTIS FUNCTION -- Introduction -- Summary And Conclusions -- References -- PARACRINE REGULATION IN THE OVARY -- Introduction -- Intraovarian Steroids -- The Role Of Ovarian Growth Factors -- Other Regulatory Peptides In The Ovarian Follicle -- Summary Of Current Efforts And Future Perspectives -- Acknowledgements -- Literature Cited -- EXPERIMENTAL APPROACHES TO THE STUDY OF EARLY DEVELOPMENTAL FAILURE IN HUMAN REPRODUCTION -- Early Developmental Failure In The Human -- The Frequency Of Chromosomal Anomalies In Human Oocytes After Ovarian Hyperstimulation -- Developmental Failure During The Perifertilization Period -- Summary -- Acknowledgement -- References -- Figure Legends -- THE FERTILIZING SPERM: STRUCTURE, MATURATION AND FUNCTION -- Introduction -- Sperm Structure.
505	8		\|a Common Themes In The Cellular Sequence Of Gamete Interaction -- A General Model For Mammallan Gamete Interaction -- Common Themes During Epididymal Transit -- For What Types Of Studies Are Model Systems Appropriate? -- Summary -- Reviews to consult for detailed information and references -- MOLECULAR EVENTS PRE-AND POST-FERTILIZATION OF MOUSE EGGS: OOCYTE MATURATION, EGG ACTIVATION, AND POLYSPERMY BLOCK -- Introduction -- Acquisition Of Meiotic Competence -- Oocyte Maturation -- 1. Role Of Camp And Protein Phosphorylation -- 2. Maturation Promoting Factor -- 3. Acquisition And Maintenance Of Sperm Decondensing Activity -- Fertilization And Egg Activation -- 1. Block To Polyspermy -- Unresolved Questions And Future Directions -- Acknowledgements -- References -- GLYCOLYTIC PATHWAY IN PREIMPLANTATION MAMMALIAN EMBRYOS -- Introduction -- Evidence That Metabolic Pathways Are Respricted In Oogenesis And Early Mammalian Development -- Morphology Of The Mitochondria During Oogenesis And Preimplantation Development -- Nutritional Studies With Chemically Defined Media -- Uptake Of Metabolic Substrates -- Metabolic Fate Of Substrates -- A Caveat-Be Alert For Artifacts -- Metabolic Fate Of Glucose -- Control Of Glycolysis -- Conclusion -- References -- REGULATIVE POTENTLAL OF MICROMANIPULATED EMBRYOS -- Introduction -- Uses Of Micromanipulation -- Types Of Manipulation -- Regulation In Mammalian Embryos -- Use Of Micromanipulation In Studying Regulation In Laboratory And Domestic Species -- Preimplantation Development -- Regulation And Cell Potential During Cleavage And Blastulation -- How Is Relation Accomplished? -- References -- UTERINE RECEPTIVITY, MATERNAL RECOGNITION OF PREGNANCY AND EARLY EMBRYONIC LOSS -- Summary -- Magnitude Of Embryonic Losses -- Causes Of Embryonic Loss -- Implantation And Placentation.
505	8		\|a Asynchrony Of Embryo And Mother Is Related To Early Embryonic Loss -- The Necessity Of The Uterine Environment -- Maternal Recognition Of Pregnancy And Pregnancy Failure -- Immunological Rejection Of Embryos -- Natural Asynchrony And Embryonic Loss -- References -- Legend to Figure -- TOWARDS A CELLULAR AND MOLECULAR UNDERSTANDING OF IMPLANTATION IN THE HUMAN: IMPLICATIONS FOR ASSISTED REPRODUCTIVE... -- Introduction -- Preparation And Characterization Of Human Cytotrophoblasts -- Trophoblast Aggregation -- Trophoblast Fusion -- Trophoblast Interactions With Extracellular Matrix -- Relationship Between Morphologic And Functional Differentiation Of The Trophoblast -- Interactions Between Trophoblast And Endometrium -- Cytotrophoblast Interactions With Endometrial Explants -- Cytotrophoblast Interactions With Endometrial Glandular Epithelium And Stroma -- Trophoblast Invasion Into The Endometrium -- Paracrine Interactions During Implantation -- A Working Model For Implantation In The Human And Future Directions For Research -- Acknowledgements -- References.
546			\|a English.
650		0	\|a Fertilization in vitro. \|0 http://id.loc.gov/authorities/subjects/sh85047905
650		0	\|a Fertilization in vitro, Human. \|0 http://id.loc.gov/authorities/subjects/sh85047906
650		0	\|a Reproductive technology. \|0 http://id.loc.gov/authorities/subjects/sh88005586
650		0	\|a Artificial insemination. \|0 http://id.loc.gov/authorities/subjects/sh85008174
650		0	\|a Human reproductive technology. \|0 http://id.loc.gov/authorities/subjects/sh88005587
650		0	\|a Embryo transplantation. \|0 http://id.loc.gov/authorities/subjects/sh85042720
650		0	\|a Research. \|0 http://id.loc.gov/authorities/subjects/sh85113021
650		0	\|a Risk. \|0 http://id.loc.gov/authorities/subjects/sh85114195
650		0	\|a Risk assessment. \|0 http://id.loc.gov/authorities/subjects/sh87002638
650		0	\|a Agriculture. \|0 http://id.loc.gov/authorities/subjects/sh85002415
650		0	\|a Animal experimentation. \|0 http://id.loc.gov/authorities/subjects/sh85005173
650		0	\|a Contraception. \|0 http://id.loc.gov/authorities/subjects/sh85031589
650		0	\|a Federal government. \|0 http://id.loc.gov/authorities/subjects/sh85047611
650		0	\|a Goal (Psychology) \|0 http://id.loc.gov/authorities/subjects/sh85055484
650		0	\|a Political science. \|0 http://id.loc.gov/authorities/subjects/sh85104440
650		0	\|a Politics, Practical. \|0 http://id.loc.gov/authorities/subjects/sh85104466
650		0	\|a Infertility. \|0 http://id.loc.gov/authorities/subjects/sh85066087
650		0	\|a International cooperation. \|0 http://id.loc.gov/authorities/subjects/sh85067385
650		0	\|a Methodology. \|0 http://id.loc.gov/authorities/subjects/sh85084414
650		0	\|a Sex preselection. \|0 http://id.loc.gov/authorities/subjects/sh85120660
650		0	\|a Social control. \|0 http://id.loc.gov/authorities/subjects/sh85123931
650	1	2	\|a Embryo Transfer
650	1	2	\|a Fertilization in Vitro
650	1	2	\|a Embryo Research
650	1	2	\|a Embryo, Mammalian
650	1	2	\|a Research
650	1	2	\|a Risk
650	1	2	\|a Risk Assessment
650		2	\|a Technology Assessment, Biomedical
650		2	\|a Insemination, Artificial \|0 https://id.nlm.nih.gov/mesh/D007315
650		2	\|a Reproductive Techniques, Assisted \|0 https://id.nlm.nih.gov/mesh/D027724
650	2	2	\|a Reproductive Techniques
650	2	2	\|a Agriculture
650	2	2	\|a Animal Experimentation
650	2	2	\|a Animal Welfare
650	2	2	\|a Biomedical Research
650	2	2	\|a Contraception
650	2	2	\|a Federal Government
650	2	2	\|a Financial Support
650	2	2	\|a Goals
650	2	2	\|a Government
650	2	2	\|a Government Regulation
650	2	2	\|a Infertility
650	2	2	\|a International Cooperation
650	2	2	\|a Internationality
650	2	2	\|a Methods
650	2	2	\|a Public Policy
650	2	2	\|a Sex Preselection
650	2	2	\|a Social Control, Formal
651		2	\|a United States
650		6	\|a Fécondation in vitro.
650		6	\|a Reproduction \|x Innovations.
650		6	\|a Insémination artificielle.
650		6	\|a Procréation médicalement assistée.
650		6	\|a Embryons \|x Transplantation.
650		6	\|a Recherche.
650		6	\|a Risque.
650		6	\|a Évaluation du risque.
650		6	\|a Agriculture.
650		6	\|a Expérimentation animale.
650		6	\|a Contraception.
650		6	\|a Gouvernement fédéral.
650		6	\|a But (Psychologie)
650		6	\|a Institutions politiques.
650		6	\|a Infertilité.
650		6	\|a Coopération internationale.
650		6	\|a Méthodologie.
650		6	\|a Sexe des enfants \|x Choix.
650		6	\|a Contrôle social.
650		7	\|a research (function) \|2 aat
650		7	\|a risk assessment. \|2 aat
650		7	\|a farming (activity or system) \|2 aat
650		7	\|a federal government. \|2 aat
650		7	\|a governments (administrative bodies) \|2 aat
650		7	\|a methodology. \|2 aat
650		7	\|a agriculture (discipline) \|2 aat
650		7	\|a HEALTH & FITNESS \|x Infertility. \|2 bisacsh
650		7	\|a Social control \|2 fast
650		7	\|a Sex preselection \|2 fast
650		7	\|a Risk assessment \|2 fast
650		7	\|a Risk \|2 fast
650		7	\|a Research \|2 fast
650		7	\|a Politics, Practical \|2 fast
650		7	\|a Political science \|2 fast
650		7	\|a Methodology \|2 fast
650		7	\|a International cooperation \|2 fast
650		7	\|a Infertility \|2 fast
650		7	\|a Goal (Psychology) \|2 fast
650		7	\|a Federal government \|2 fast
650		7	\|a Embryo transplantation \|2 fast
650		7	\|a Contraception \|2 fast
650		7	\|a Animal experimentation \|2 fast
650		7	\|a Agriculture \|2 fast
650		7	\|a Artificial insemination \|2 fast
650		7	\|a Fertilization in vitro \|2 fast
650		7	\|a Fertilization in vitro, Human \|2 fast
650		7	\|a Human reproductive technology \|2 fast
650		7	\|a Reproductive technology \|2 fast
700	1		\|a Ryan, Kenneth J., \|d 1926-2002. \|1 https://id.oclc.org/worldcat/entity/E39PBJtxgy4mhHT7r3jXMfKmVC \|0 http://id.loc.gov/authorities/names/n80032109
710	2		\|a Institute of Medicine (U.S.). \|b Division of Health Sciences Policy. \|0 http://id.loc.gov/authorities/names/n79066824
710	2		\|a National Research Council (U.S.). \|b Board on Agriculture. \|0 http://id.loc.gov/authorities/names/n85128793
776	0	8	\|i Print version: \|a Committee on the Basic Science Foundations of Medically Assisted Conception. \|t Medically assisted conception. \|d Washington, D.C. : National Academy Press, 1989 \|z 0309041287 \|w (DLC) 89063252 \|w (OCoLC)22548545
830		0	\|a IOM publication ; \|v 89-008. \|0 http://id.loc.gov/authorities/names/n42031273
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contents	Medically Assisted Conception -- Copyright -- Contents -- Acknowledgements -- Preface -- SCOPE OF THE STUDY -- Summary -- SOCIAL CONCERNS THAT CAN BE ADDRESSED BY IVFET -- BARRIERS TO PROGRESS IN IN VITRO FERTILIZATION AND EMBRYO TRANSFER -- Ethical And Social Issues -- The Federal Government And Embryo Research -- Domestic And Foreign Decisions Concerning Embryo Research -- Other Barriers To Scientific Progress -- RESEARCH AGENDA -- Basic Science -- Male Gametogenesis -- Female Gametogenesis -- Fertilization -- Preimplantation Development -- Implantation -- Technological Advances -- Clinical Research Opportunities -- CONCLUSIONS AND RECOMMENDATIONS -- Developing Research Policy -- Basic Science Foundations -- Applied Research -- Clinical Research Opportunities -- Improving Communications -- REFERENCES -- Chapter 1 In Vitro Fertilization And Embryo Transfer And Social Concerns -- INFERTILITY -- Treatments For Infertility -- In Vitro Fertilization And Embryo Transfer -- Gamete Intrafallopian Transfer -- Donated Gametes Or Concepti -- CONTRACEPTION -- AGRICULTURE -- BIODIVERSITY -- PRIMATES FOR RESEARCH -- REFERENCES -- Chapter 2 Advances In The Practice And Science Base Of Medical, Assisted Conception -- DEVELOPMENTS IN HUMAN IN VITRO FERTILIZATION [ 1 ] -- DEVELOPMENTS IN ASSISTED CONCEPTION IN FOOD-PRODUCING ANIMALS [ 2 ] -- GAMETOGENESIS AND GAMETES -- Induction Of Gametogenesis And Superovulation [ 3 ] -- Biology And Maturation [ 4 ] -- Intratesticular And Intraovarian Paracrine Control [ 5 ] -- Assessment Of Gametes [ 6 ] -- FERTILIZATION [ 7 ] -- PREIMPLANTATION DEVELOPMENT [ 8 ] -- Metabolic Substrates And Pathways -- Gene Expression In Early Embryonic Development -- Regulative Potential Of Micromanipulated Embryos -- IMPLANTATION [ 9 ] -- ENDNOTES -- Chapter 3 Barriers To Progress In In Vitro Fertilization And Embryo Transfer. ETHICAL AND SOCIAL ISSUES -- The Federal Government And Embryo Research -- Domestic And Foreign Decisions On Embryo Research -- OTHER BARRIERS TO SCIENTIFIC PROGRESS -- Deficiencies In The Science Base -- Research Funding -- Lack Of Communication Among Researchers -- Societal Concerns -- Sources Of Research Material -- REFERENCES -- Chapter 4 Research Agenda And Recommendations -- RESEARCH AGENDA -- Basic Science -- Male Gametogenesis -- Female Gametogenesis -- Fertilization -- Preimplantation Development -- Implantation -- Technological Advances -- Clinical Research Opportunities -- CONCLUSIONS AND RECOMMENDATIONS -- Developing Research Policy -- Basic Science Foundations -- Applied Research -- Clinical Research Opportunities -- Improving Communications -- Appendix A Committee On Basic Science Foundations Of Medically Assisted Conception -- TECHNOLOGIES FOR ASSISTED CONCEPTION/EMBRYO TRANSFER IN AGRICULTURAL AND VETERINARY PRACTICE -- Introduction -- Artificial Insemination -- Superovulation -- Embryo Transfer -- Freezing Of Embryos -- Sexing Of Embryos -- Sexing By Y Chromosome Specific Dna Hybridization -- Multiplication Of Embryos -- Nuclear Transfer -- In Vitro Production Of Embryos -- Oocyte Maturation -- In Vitro Fertilization -- Development Of Embryos In Vitro -- Gene Transfer -- Conclusions -- References -- OVARIAN STIMULATION IN NON-HUMAN PRIMATES -- Introduction -- The Menstrual Cycle -- Regulation Of Folliculogenesis -- Ovarian Stimulation -- Problems With Stimulated Ovarian Function -- Solutions For Problems With Stimulated Ovarian Function -- Acknowledgement -- References -- RESPONSES TO GONADOTROPINS IN DOMESTIC ANIMALS -- Introduction -- Superovulation In Domestic Animals -- Superovulation Of Cattle -- Superovulation Of Sheep And Goats -- Effects Of Exogenous Gonadotropins On Horses -- Ovulation Induction In Pigs. Recommendations For Future Directions In Research -- Summary -- References -- MEMBRANE MODELS: EVOLUTION FROM THE FLUID-MOSAIC STANDBY ROY HAMMERSTEDT -- Introduction -- Complexity Of The Cell Surface -- Asymmetry Of Cell Surfaces -- Lipid Domains -- Relative Speed Of Membrane Events -- Spatial Relationships On The Membrane Surface -- Summary -- Acknowledgements -- References -- MAMMALIAN OOCYTE MATURATION: MECHANISMS FOR REGULATION AND PROSPECTS FOR PRACTICAL APPLICATION OF IN VITRO TECHNOLOGY -- The Ovarian Follicle As The Support System For Oocyte Development In Vivo -- Identification Of Molecules And Pathways That Participate In The Maintenance Of Meiotic Arrest -- Induction Of Oocyte Maturation -- Similarities Between Mechanisms That Govern Meiotic and Mitotic Cell Division -- Murine Oocyte Growth And Development In Culture -- Prospects For The Practical Utilization Of Oocyte Culture Systems -- Expansion Of Populations Of Rare Or Agriculturally Important Mammals -- Acknowledgments -- References -- INTRAGONADAL CONTROL OF TESTIS FUNCTION -- Introduction -- Summary And Conclusions -- References -- PARACRINE REGULATION IN THE OVARY -- Introduction -- Intraovarian Steroids -- The Role Of Ovarian Growth Factors -- Other Regulatory Peptides In The Ovarian Follicle -- Summary Of Current Efforts And Future Perspectives -- Acknowledgements -- Literature Cited -- EXPERIMENTAL APPROACHES TO THE STUDY OF EARLY DEVELOPMENTAL FAILURE IN HUMAN REPRODUCTION -- Early Developmental Failure In The Human -- The Frequency Of Chromosomal Anomalies In Human Oocytes After Ovarian Hyperstimulation -- Developmental Failure During The Perifertilization Period -- Summary -- Acknowledgement -- References -- Figure Legends -- THE FERTILIZING SPERM: STRUCTURE, MATURATION AND FUNCTION -- Introduction -- Sperm Structure. Common Themes In The Cellular Sequence Of Gamete Interaction -- A General Model For Mammallan Gamete Interaction -- Common Themes During Epididymal Transit -- For What Types Of Studies Are Model Systems Appropriate? -- Summary -- Reviews to consult for detailed information and references -- MOLECULAR EVENTS PRE-AND POST-FERTILIZATION OF MOUSE EGGS: OOCYTE MATURATION, EGG ACTIVATION, AND POLYSPERMY BLOCK -- Introduction -- Acquisition Of Meiotic Competence -- Oocyte Maturation -- 1. Role Of Camp And Protein Phosphorylation -- 2. Maturation Promoting Factor -- 3. Acquisition And Maintenance Of Sperm Decondensing Activity -- Fertilization And Egg Activation -- 1. Block To Polyspermy -- Unresolved Questions And Future Directions -- Acknowledgements -- References -- GLYCOLYTIC PATHWAY IN PREIMPLANTATION MAMMALIAN EMBRYOS -- Introduction -- Evidence That Metabolic Pathways Are Respricted In Oogenesis And Early Mammalian Development -- Morphology Of The Mitochondria During Oogenesis And Preimplantation Development -- Nutritional Studies With Chemically Defined Media -- Uptake Of Metabolic Substrates -- Metabolic Fate Of Substrates -- A Caveat-Be Alert For Artifacts -- Metabolic Fate Of Glucose -- Control Of Glycolysis -- Conclusion -- References -- REGULATIVE POTENTLAL OF MICROMANIPULATED EMBRYOS -- Introduction -- Uses Of Micromanipulation -- Types Of Manipulation -- Regulation In Mammalian Embryos -- Use Of Micromanipulation In Studying Regulation In Laboratory And Domestic Species -- Preimplantation Development -- Regulation And Cell Potential During Cleavage And Blastulation -- How Is Relation Accomplished? -- References -- UTERINE RECEPTIVITY, MATERNAL RECOGNITION OF PREGNANCY AND EARLY EMBRYONIC LOSS -- Summary -- Magnitude Of Embryonic Losses -- Causes Of Embryonic Loss -- Implantation And Placentation. Asynchrony Of Embryo And Mother Is Related To Early Embryonic Loss -- The Necessity Of The Uterine Environment -- Maternal Recognition Of Pregnancy And Pregnancy Failure -- Immunological Rejection Of Embryos -- Natural Asynchrony And Embryonic Loss -- References -- Legend to Figure -- TOWARDS A CELLULAR AND MOLECULAR UNDERSTANDING OF IMPLANTATION IN THE HUMAN: IMPLICATIONS FOR ASSISTED REPRODUCTIVE... -- Introduction -- Preparation And Characterization Of Human Cytotrophoblasts -- Trophoblast Aggregation -- Trophoblast Fusion -- Trophoblast Interactions With Extracellular Matrix -- Relationship Between Morphologic And Functional Differentiation Of The Trophoblast -- Interactions Between Trophoblast And Endometrium -- Cytotrophoblast Interactions With Endometrial Explants -- Cytotrophoblast Interactions With Endometrial Glandular Epithelium And Stroma -- Trophoblast Invasion Into The Endometrium -- Paracrine Interactions During Implantation -- A Working Model For Implantation In The Human And Future Directions For Research -- Acknowledgements -- References.
ctrlnum	(OCoLC)45733567
dewey-full	618.1/78059
dewey-hundreds	600 - Technology (Applied sciences)
dewey-ones	618 - Gynecology, obstetrics, pediatrics, geriatrics
dewey-raw	618.1/78059
dewey-search	618.1/78059
dewey-sort	3618.1 578059
dewey-tens	610 - Medicine and health
discipline	Medizin
format	Electronic eBook
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code="a">Committee on the Basic Science Foundations of Medically Assisted Conception.</subfield><subfield code="0">http://id.loc.gov/authorities/names/n88008492</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Medically assisted conception :</subfield><subfield code="b">an agenda for research : report of a study /</subfield><subfield code="c">by a committee of the Institute of Medicine, Division of Health Sciences Policy, National Research Council, Board on Agriculture.</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="a">Washington, D.C. :</subfield><subfield code="b">National Academy Press,</subfield><subfield code="c">1989.</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource (viii, 361 pages) :</subfield><subfield code="b">illustrations</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield 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Basic Science Foundation of Medically Assisted Conception.</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Committee chairman: Kenneth J. Ryan.</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">" ... project received support from the National Academy of Sciences Basic Science Fund and the U.S. Department of Agriculture (contract 59-32U4-8-63/R)."</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">On cover: Report of a study and workshop papers.</subfield></datafield><datafield tag="504" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references.</subfield></datafield><datafield tag="588" ind1="0" ind2=" "><subfield code="a">Print version record.</subfield></datafield><datafield tag="506" ind1=" " ind2=" "><subfield code="3">Use copy</subfield><subfield code="f">Restrictions unspecified</subfield><subfield code="2">star</subfield><subfield code="5">MiAaHDL</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="a">Electronic reproduction.</subfield><subfield code="b">[Place of publication not identified] :</subfield><subfield code="c">HathiTrust Digital Library,</subfield><subfield code="d">2010.</subfield><subfield code="5">MiAaHDL</subfield></datafield><datafield tag="538" ind1=" " ind2=" "><subfield code="a">Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.</subfield><subfield code="u">http://purl.oclc.org/DLF/benchrepro0212</subfield><subfield code="5">MiAaHDL</subfield></datafield><datafield tag="583" ind1="1" ind2=" "><subfield code="a">digitized</subfield><subfield code="c">2010</subfield><subfield code="h">HathiTrust Digital Library</subfield><subfield code="l">committed to preserve</subfield><subfield code="2">pda</subfield><subfield code="5">MiAaHDL</subfield></datafield><datafield tag="505" ind1="0" ind2=" "><subfield code="a">Medically Assisted Conception -- Copyright -- Contents -- Acknowledgements -- Preface -- SCOPE OF THE STUDY -- Summary -- SOCIAL CONCERNS THAT CAN BE ADDRESSED BY IVFET -- BARRIERS TO PROGRESS IN IN VITRO FERTILIZATION AND EMBRYO TRANSFER -- Ethical And Social Issues -- The Federal Government And Embryo Research -- Domestic And Foreign Decisions Concerning Embryo Research -- Other Barriers To Scientific Progress -- RESEARCH AGENDA -- Basic Science -- Male Gametogenesis -- Female Gametogenesis -- Fertilization -- Preimplantation Development -- Implantation -- Technological Advances -- Clinical Research Opportunities -- CONCLUSIONS AND RECOMMENDATIONS -- Developing Research Policy -- Basic Science Foundations -- Applied Research -- Clinical Research Opportunities -- Improving Communications -- REFERENCES -- Chapter 1 In Vitro Fertilization And Embryo Transfer And Social Concerns -- INFERTILITY -- Treatments For Infertility -- In Vitro Fertilization And Embryo Transfer -- Gamete Intrafallopian Transfer -- Donated Gametes Or Concepti -- CONTRACEPTION -- AGRICULTURE -- BIODIVERSITY -- PRIMATES FOR RESEARCH -- REFERENCES -- Chapter 2 Advances In The Practice And Science Base Of Medical, Assisted Conception -- DEVELOPMENTS IN HUMAN IN VITRO FERTILIZATION [ 1 ] -- DEVELOPMENTS IN ASSISTED CONCEPTION IN FOOD-PRODUCING ANIMALS [ 2 ] -- GAMETOGENESIS AND GAMETES -- Induction Of Gametogenesis And Superovulation [ 3 ] -- Biology And Maturation [ 4 ] -- Intratesticular And Intraovarian Paracrine Control [ 5 ] -- Assessment Of Gametes [ 6 ] -- FERTILIZATION [ 7 ] -- PREIMPLANTATION DEVELOPMENT [ 8 ] -- Metabolic Substrates And Pathways -- Gene Expression In Early Embryonic Development -- Regulative Potential Of Micromanipulated Embryos -- IMPLANTATION [ 9 ] -- ENDNOTES -- Chapter 3 Barriers To Progress In In Vitro Fertilization And Embryo Transfer.</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">ETHICAL AND SOCIAL ISSUES -- The Federal Government And Embryo Research -- Domestic And Foreign Decisions On Embryo Research -- OTHER BARRIERS TO SCIENTIFIC PROGRESS -- Deficiencies In The Science Base -- Research Funding -- Lack Of Communication Among Researchers -- Societal Concerns -- Sources Of Research Material -- REFERENCES -- Chapter 4 Research Agenda And Recommendations -- RESEARCH AGENDA -- Basic Science -- Male Gametogenesis -- Female Gametogenesis -- Fertilization -- Preimplantation Development -- Implantation -- Technological Advances -- Clinical Research Opportunities -- CONCLUSIONS AND RECOMMENDATIONS -- Developing Research Policy -- Basic Science Foundations -- Applied Research -- Clinical Research Opportunities -- Improving Communications -- Appendix A Committee On Basic Science Foundations Of Medically Assisted Conception -- TECHNOLOGIES FOR ASSISTED CONCEPTION/EMBRYO TRANSFER IN AGRICULTURAL AND VETERINARY PRACTICE -- Introduction -- Artificial Insemination -- Superovulation -- Embryo Transfer -- Freezing Of Embryos -- Sexing Of Embryos -- Sexing By Y Chromosome Specific Dna Hybridization -- Multiplication Of Embryos -- Nuclear Transfer -- In Vitro Production Of Embryos -- Oocyte Maturation -- In Vitro Fertilization -- Development Of Embryos In Vitro -- Gene Transfer -- Conclusions -- References -- OVARIAN STIMULATION IN NON-HUMAN PRIMATES -- Introduction -- The Menstrual Cycle -- Regulation Of Folliculogenesis -- Ovarian Stimulation -- Problems With Stimulated Ovarian Function -- Solutions For Problems With Stimulated Ovarian Function -- Acknowledgement -- References -- RESPONSES TO GONADOTROPINS IN DOMESTIC ANIMALS -- Introduction -- Superovulation In Domestic Animals -- Superovulation Of Cattle -- Superovulation Of Sheep And Goats -- Effects Of Exogenous Gonadotropins On Horses -- Ovulation Induction In Pigs.</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">Recommendations For Future Directions In Research -- Summary -- References -- MEMBRANE MODELS: EVOLUTION FROM THE FLUID-MOSAIC STANDBY ROY HAMMERSTEDT -- Introduction -- Complexity Of The Cell Surface -- Asymmetry Of Cell Surfaces -- Lipid Domains -- Relative Speed Of Membrane Events -- Spatial Relationships On The Membrane Surface -- Summary -- Acknowledgements -- References -- MAMMALIAN OOCYTE MATURATION: MECHANISMS FOR REGULATION AND PROSPECTS FOR PRACTICAL APPLICATION OF IN VITRO TECHNOLOGY -- The Ovarian Follicle As The Support System For Oocyte Development In Vivo -- Identification Of Molecules And Pathways That Participate In The Maintenance Of Meiotic Arrest -- Induction Of Oocyte Maturation -- Similarities Between Mechanisms That Govern Meiotic and Mitotic Cell Division -- Murine Oocyte Growth And Development In Culture -- Prospects For The Practical Utilization Of Oocyte Culture Systems -- Expansion Of Populations Of Rare Or Agriculturally Important Mammals -- Acknowledgments -- References -- INTRAGONADAL CONTROL OF TESTIS FUNCTION -- Introduction -- Summary And Conclusions -- References -- PARACRINE REGULATION IN THE OVARY -- Introduction -- Intraovarian Steroids -- The Role Of Ovarian Growth Factors -- Other Regulatory Peptides In The Ovarian Follicle -- Summary Of Current Efforts And Future Perspectives -- Acknowledgements -- Literature Cited -- EXPERIMENTAL APPROACHES TO THE STUDY OF EARLY DEVELOPMENTAL FAILURE IN HUMAN REPRODUCTION -- Early Developmental Failure In The Human -- The Frequency Of Chromosomal Anomalies In Human Oocytes After Ovarian Hyperstimulation -- Developmental Failure During The Perifertilization Period -- Summary -- Acknowledgement -- References -- Figure Legends -- THE FERTILIZING SPERM: STRUCTURE, MATURATION AND FUNCTION -- Introduction -- Sperm Structure.</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">Common Themes In The Cellular Sequence Of Gamete Interaction -- A General Model For Mammallan Gamete Interaction -- Common Themes During Epididymal Transit -- For What Types Of Studies Are Model Systems Appropriate? -- Summary -- Reviews to consult for detailed information and references -- MOLECULAR EVENTS PRE-AND POST-FERTILIZATION OF MOUSE EGGS: OOCYTE MATURATION, EGG ACTIVATION, AND POLYSPERMY BLOCK -- Introduction -- Acquisition Of Meiotic Competence -- Oocyte Maturation -- 1. Role Of Camp And Protein Phosphorylation -- 2. Maturation Promoting Factor -- 3. Acquisition And Maintenance Of Sperm Decondensing Activity -- Fertilization And Egg Activation -- 1. Block To Polyspermy -- Unresolved Questions And Future Directions -- Acknowledgements -- References -- GLYCOLYTIC PATHWAY IN PREIMPLANTATION MAMMALIAN EMBRYOS -- Introduction -- Evidence That Metabolic Pathways Are Respricted In Oogenesis And Early Mammalian Development -- Morphology Of The Mitochondria During Oogenesis And Preimplantation Development -- Nutritional Studies With Chemically Defined Media -- Uptake Of Metabolic Substrates -- Metabolic Fate Of Substrates -- A Caveat-Be Alert For Artifacts -- Metabolic Fate Of Glucose -- Control Of Glycolysis -- Conclusion -- References -- REGULATIVE POTENTLAL OF MICROMANIPULATED EMBRYOS -- Introduction -- Uses Of Micromanipulation -- Types Of Manipulation -- Regulation In Mammalian Embryos -- Use Of Micromanipulation In Studying Regulation In Laboratory And Domestic Species -- Preimplantation Development -- Regulation And Cell Potential During Cleavage And Blastulation -- How Is Relation Accomplished? -- References -- UTERINE RECEPTIVITY, 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id	ZDB-4-EBA-ocm45733567
illustrated	Illustrated
indexdate	2024-11-27T13:15:10Z
institution	BVB
institution_GND	http://id.loc.gov/authorities/names/n88008492 http://id.loc.gov/authorities/names/n79066824 http://id.loc.gov/authorities/names/n85128793
isbn	0585154163 9780585154169 9780309559836 0309559839 1280214287 9781280214288 9786610214280 661021428X
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spelling	Committee on the Basic Science Foundations of Medically Assisted Conception. http://id.loc.gov/authorities/names/n88008492 Medically assisted conception : an agenda for research : report of a study / by a committee of the Institute of Medicine, Division of Health Sciences Policy, National Research Council, Board on Agriculture. Washington, D.C. : National Academy Press, 1989. 1 online resource (viii, 361 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier polychrome. rdacc http://rdaregistry.info/termList/RDAColourContent/1003 text file rdaft http://rdaregistry.info/termList/fileType/1002 IOM ; 89-08 Report prepared by the Committee on the Basic Science Foundation of Medically Assisted Conception. Committee chairman: Kenneth J. Ryan. " ... project received support from the National Academy of Sciences Basic Science Fund and the U.S. Department of Agriculture (contract 59-32U4-8-63/R)." On cover: Report of a study and workshop papers. Includes bibliographical references. Print version record. Use copy Restrictions unspecified star MiAaHDL Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010. MiAaHDL Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL Medically Assisted Conception -- Copyright -- Contents -- Acknowledgements -- Preface -- SCOPE OF THE STUDY -- Summary -- SOCIAL CONCERNS THAT CAN BE ADDRESSED BY IVFET -- BARRIERS TO PROGRESS IN IN VITRO FERTILIZATION AND EMBRYO TRANSFER -- Ethical And Social Issues -- The Federal Government And Embryo Research -- Domestic And Foreign Decisions Concerning Embryo Research -- Other Barriers To Scientific Progress -- RESEARCH AGENDA -- Basic Science -- Male Gametogenesis -- Female Gametogenesis -- Fertilization -- Preimplantation Development -- Implantation -- Technological Advances -- Clinical Research Opportunities -- CONCLUSIONS AND RECOMMENDATIONS -- Developing Research Policy -- Basic Science Foundations -- Applied Research -- Clinical Research Opportunities -- Improving Communications -- REFERENCES -- Chapter 1 In Vitro Fertilization And Embryo Transfer And Social Concerns -- INFERTILITY -- Treatments For Infertility -- In Vitro Fertilization And Embryo Transfer -- Gamete Intrafallopian Transfer -- Donated Gametes Or Concepti -- CONTRACEPTION -- AGRICULTURE -- BIODIVERSITY -- PRIMATES FOR RESEARCH -- REFERENCES -- Chapter 2 Advances In The Practice And Science Base Of Medical, Assisted Conception -- DEVELOPMENTS IN HUMAN IN VITRO FERTILIZATION [ 1 ] -- DEVELOPMENTS IN ASSISTED CONCEPTION IN FOOD-PRODUCING ANIMALS [ 2 ] -- GAMETOGENESIS AND GAMETES -- Induction Of Gametogenesis And Superovulation [ 3 ] -- Biology And Maturation [ 4 ] -- Intratesticular And Intraovarian Paracrine Control [ 5 ] -- Assessment Of Gametes [ 6 ] -- FERTILIZATION [ 7 ] -- PREIMPLANTATION DEVELOPMENT [ 8 ] -- Metabolic Substrates And Pathways -- Gene Expression In Early Embryonic Development -- Regulative Potential Of Micromanipulated Embryos -- IMPLANTATION [ 9 ] -- ENDNOTES -- Chapter 3 Barriers To Progress In In Vitro Fertilization And Embryo Transfer. ETHICAL AND SOCIAL ISSUES -- The Federal Government And Embryo Research -- Domestic And Foreign Decisions On Embryo Research -- OTHER BARRIERS TO SCIENTIFIC PROGRESS -- Deficiencies In The Science Base -- Research Funding -- Lack Of Communication Among Researchers -- Societal Concerns -- Sources Of Research Material -- REFERENCES -- Chapter 4 Research Agenda And Recommendations -- RESEARCH AGENDA -- Basic Science -- Male Gametogenesis -- Female Gametogenesis -- Fertilization -- Preimplantation Development -- Implantation -- Technological Advances -- Clinical Research Opportunities -- CONCLUSIONS AND RECOMMENDATIONS -- Developing Research Policy -- Basic Science Foundations -- Applied Research -- Clinical Research Opportunities -- Improving Communications -- Appendix A Committee On Basic Science Foundations Of Medically Assisted Conception -- TECHNOLOGIES FOR ASSISTED CONCEPTION/EMBRYO TRANSFER IN AGRICULTURAL AND VETERINARY PRACTICE -- Introduction -- Artificial Insemination -- Superovulation -- Embryo Transfer -- Freezing Of Embryos -- Sexing Of Embryos -- Sexing By Y Chromosome Specific Dna Hybridization -- Multiplication Of Embryos -- Nuclear Transfer -- In Vitro Production Of Embryos -- Oocyte Maturation -- In Vitro Fertilization -- Development Of Embryos In Vitro -- Gene Transfer -- Conclusions -- References -- OVARIAN STIMULATION IN NON-HUMAN PRIMATES -- Introduction -- The Menstrual Cycle -- Regulation Of Folliculogenesis -- Ovarian Stimulation -- Problems With Stimulated Ovarian Function -- Solutions For Problems With Stimulated Ovarian Function -- Acknowledgement -- References -- RESPONSES TO GONADOTROPINS IN DOMESTIC ANIMALS -- Introduction -- Superovulation In Domestic Animals -- Superovulation Of Cattle -- Superovulation Of Sheep And Goats -- Effects Of Exogenous Gonadotropins On Horses -- Ovulation Induction In Pigs. Recommendations For Future Directions In Research -- Summary -- References -- MEMBRANE MODELS: EVOLUTION FROM THE FLUID-MOSAIC STANDBY ROY HAMMERSTEDT -- Introduction -- Complexity Of The Cell Surface -- Asymmetry Of Cell Surfaces -- Lipid Domains -- Relative Speed Of Membrane Events -- Spatial Relationships On The Membrane Surface -- Summary -- Acknowledgements -- References -- MAMMALIAN OOCYTE MATURATION: MECHANISMS FOR REGULATION AND PROSPECTS FOR PRACTICAL APPLICATION OF IN VITRO TECHNOLOGY -- The Ovarian Follicle As The Support System For Oocyte Development In Vivo -- Identification Of Molecules And Pathways That Participate In The Maintenance Of Meiotic Arrest -- Induction Of Oocyte Maturation -- Similarities Between Mechanisms That Govern Meiotic and Mitotic Cell Division -- Murine Oocyte Growth And Development In Culture -- Prospects For The Practical Utilization Of Oocyte Culture Systems -- Expansion Of Populations Of Rare Or Agriculturally Important Mammals -- Acknowledgments -- References -- INTRAGONADAL CONTROL OF TESTIS FUNCTION -- Introduction -- Summary And Conclusions -- References -- PARACRINE REGULATION IN THE OVARY -- Introduction -- Intraovarian Steroids -- The Role Of Ovarian Growth Factors -- Other Regulatory Peptides In The Ovarian Follicle -- Summary Of Current Efforts And Future Perspectives -- Acknowledgements -- Literature Cited -- EXPERIMENTAL APPROACHES TO THE STUDY OF EARLY DEVELOPMENTAL FAILURE IN HUMAN REPRODUCTION -- Early Developmental Failure In The Human -- The Frequency Of Chromosomal Anomalies In Human Oocytes After Ovarian Hyperstimulation -- Developmental Failure During The Perifertilization Period -- Summary -- Acknowledgement -- References -- Figure Legends -- THE FERTILIZING SPERM: STRUCTURE, MATURATION AND FUNCTION -- Introduction -- Sperm Structure. Common Themes In The Cellular Sequence Of Gamete Interaction -- A General Model For Mammallan Gamete Interaction -- Common Themes During Epididymal Transit -- For What Types Of Studies Are Model Systems Appropriate? -- Summary -- Reviews to consult for detailed information and references -- MOLECULAR EVENTS PRE-AND POST-FERTILIZATION OF MOUSE EGGS: OOCYTE MATURATION, EGG ACTIVATION, AND POLYSPERMY BLOCK -- Introduction -- Acquisition Of Meiotic Competence -- Oocyte Maturation -- 1. Role Of Camp And Protein Phosphorylation -- 2. Maturation Promoting Factor -- 3. Acquisition And Maintenance Of Sperm Decondensing Activity -- Fertilization And Egg Activation -- 1. Block To Polyspermy -- Unresolved Questions And Future Directions -- Acknowledgements -- References -- GLYCOLYTIC PATHWAY IN PREIMPLANTATION MAMMALIAN EMBRYOS -- Introduction -- Evidence That Metabolic Pathways Are Respricted In Oogenesis And Early Mammalian Development -- Morphology Of The Mitochondria During Oogenesis And Preimplantation Development -- Nutritional Studies With Chemically Defined Media -- Uptake Of Metabolic Substrates -- Metabolic Fate Of Substrates -- A Caveat-Be Alert For Artifacts -- Metabolic Fate Of Glucose -- Control Of Glycolysis -- Conclusion -- References -- REGULATIVE POTENTLAL OF MICROMANIPULATED EMBRYOS -- Introduction -- Uses Of Micromanipulation -- Types Of Manipulation -- Regulation In Mammalian Embryos -- Use Of Micromanipulation In Studying Regulation In Laboratory And Domestic Species -- Preimplantation Development -- Regulation And Cell Potential During Cleavage And Blastulation -- How Is Relation Accomplished? -- References -- UTERINE RECEPTIVITY, MATERNAL RECOGNITION OF PREGNANCY AND EARLY EMBRYONIC LOSS -- Summary -- Magnitude Of Embryonic Losses -- Causes Of Embryonic Loss -- Implantation And Placentation. Asynchrony Of Embryo And Mother Is Related To Early Embryonic Loss -- The Necessity Of The Uterine Environment -- Maternal Recognition Of Pregnancy And Pregnancy Failure -- Immunological Rejection Of Embryos -- Natural Asynchrony And Embryonic Loss -- References -- Legend to Figure -- TOWARDS A CELLULAR AND MOLECULAR UNDERSTANDING OF IMPLANTATION IN THE HUMAN: IMPLICATIONS FOR ASSISTED REPRODUCTIVE... -- Introduction -- Preparation And Characterization Of Human Cytotrophoblasts -- Trophoblast Aggregation -- Trophoblast Fusion -- Trophoblast Interactions With Extracellular Matrix -- Relationship Between Morphologic And Functional Differentiation Of The Trophoblast -- Interactions Between Trophoblast And Endometrium -- Cytotrophoblast Interactions With Endometrial Explants -- Cytotrophoblast Interactions With Endometrial Glandular Epithelium And Stroma -- Trophoblast Invasion Into The Endometrium -- Paracrine Interactions During Implantation -- A Working Model For Implantation In The Human And Future Directions For Research -- Acknowledgements -- References. English. Fertilization in vitro. http://id.loc.gov/authorities/subjects/sh85047905 Fertilization in vitro, Human. http://id.loc.gov/authorities/subjects/sh85047906 Reproductive technology. http://id.loc.gov/authorities/subjects/sh88005586 Artificial insemination. http://id.loc.gov/authorities/subjects/sh85008174 Human reproductive technology. http://id.loc.gov/authorities/subjects/sh88005587 Embryo transplantation. http://id.loc.gov/authorities/subjects/sh85042720 Research. http://id.loc.gov/authorities/subjects/sh85113021 Risk. http://id.loc.gov/authorities/subjects/sh85114195 Risk assessment. http://id.loc.gov/authorities/subjects/sh87002638 Agriculture. http://id.loc.gov/authorities/subjects/sh85002415 Animal experimentation. http://id.loc.gov/authorities/subjects/sh85005173 Contraception. http://id.loc.gov/authorities/subjects/sh85031589 Federal government. http://id.loc.gov/authorities/subjects/sh85047611 Goal (Psychology) http://id.loc.gov/authorities/subjects/sh85055484 Political science. http://id.loc.gov/authorities/subjects/sh85104440 Politics, Practical. http://id.loc.gov/authorities/subjects/sh85104466 Infertility. http://id.loc.gov/authorities/subjects/sh85066087 International cooperation. http://id.loc.gov/authorities/subjects/sh85067385 Methodology. http://id.loc.gov/authorities/subjects/sh85084414 Sex preselection. http://id.loc.gov/authorities/subjects/sh85120660 Social control. http://id.loc.gov/authorities/subjects/sh85123931 Embryo Transfer Fertilization in Vitro Embryo Research Embryo, Mammalian Research Risk Risk Assessment Technology Assessment, Biomedical Insemination, Artificial https://id.nlm.nih.gov/mesh/D007315 Reproductive Techniques, Assisted https://id.nlm.nih.gov/mesh/D027724 Reproductive Techniques Agriculture Animal Experimentation Animal Welfare Biomedical Research Contraception Federal Government Financial Support Goals Government Government Regulation Infertility International Cooperation Internationality Methods Public Policy Sex Preselection Social Control, Formal United States Fécondation in vitro. Reproduction Innovations. Insémination artificielle. Procréation médicalement assistée. Embryons Transplantation. Recherche. Risque. Évaluation du risque. Agriculture. Expérimentation animale. Contraception. Gouvernement fédéral. But (Psychologie) Institutions politiques. Infertilité. Coopération internationale. Méthodologie. Sexe des enfants Choix. Contrôle social. research (function) aat risk assessment. aat farming (activity or system) aat federal government. aat governments (administrative bodies) aat methodology. aat agriculture (discipline) aat HEALTH & FITNESS Infertility. bisacsh Social control fast Sex preselection fast Risk assessment fast Risk fast Research fast Politics, Practical fast Political science fast Methodology fast International cooperation fast Infertility fast Goal (Psychology) fast Federal government fast Embryo transplantation fast Contraception fast Animal experimentation fast Agriculture fast Artificial insemination fast Fertilization in vitro fast Fertilization in vitro, Human fast Human reproductive technology fast Reproductive technology fast Ryan, Kenneth J., 1926-2002. https://id.oclc.org/worldcat/entity/E39PBJtxgy4mhHT7r3jXMfKmVC http://id.loc.gov/authorities/names/n80032109 Institute of Medicine (U.S.). Division of Health Sciences Policy. http://id.loc.gov/authorities/names/n79066824 National Research Council (U.S.). Board on Agriculture. http://id.loc.gov/authorities/names/n85128793 Print version: Committee on the Basic Science Foundations of Medically Assisted Conception. Medically assisted conception. Washington, D.C. : National Academy Press, 1989 0309041287 (DLC) 89063252 (OCoLC)22548545 IOM publication ; 89-008. http://id.loc.gov/authorities/names/n42031273 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=14514 Volltext
spellingShingle	Medically assisted conception : an agenda for research : report of a study / IOM publication ; Medically Assisted Conception -- Copyright -- Contents -- Acknowledgements -- Preface -- SCOPE OF THE STUDY -- Summary -- SOCIAL CONCERNS THAT CAN BE ADDRESSED BY IVFET -- BARRIERS TO PROGRESS IN IN VITRO FERTILIZATION AND EMBRYO TRANSFER -- Ethical And Social Issues -- The Federal Government And Embryo Research -- Domestic And Foreign Decisions Concerning Embryo Research -- Other Barriers To Scientific Progress -- RESEARCH AGENDA -- Basic Science -- Male Gametogenesis -- Female Gametogenesis -- Fertilization -- Preimplantation Development -- Implantation -- Technological Advances -- Clinical Research Opportunities -- CONCLUSIONS AND RECOMMENDATIONS -- Developing Research Policy -- Basic Science Foundations -- Applied Research -- Clinical Research Opportunities -- Improving Communications -- REFERENCES -- Chapter 1 In Vitro Fertilization And Embryo Transfer And Social Concerns -- INFERTILITY -- Treatments For Infertility -- In Vitro Fertilization And Embryo Transfer -- Gamete Intrafallopian Transfer -- Donated Gametes Or Concepti -- CONTRACEPTION -- AGRICULTURE -- BIODIVERSITY -- PRIMATES FOR RESEARCH -- REFERENCES -- Chapter 2 Advances In The Practice And Science Base Of Medical, Assisted Conception -- DEVELOPMENTS IN HUMAN IN VITRO FERTILIZATION [ 1 ] -- DEVELOPMENTS IN ASSISTED CONCEPTION IN FOOD-PRODUCING ANIMALS [ 2 ] -- GAMETOGENESIS AND GAMETES -- Induction Of Gametogenesis And Superovulation [ 3 ] -- Biology And Maturation [ 4 ] -- Intratesticular And Intraovarian Paracrine Control [ 5 ] -- Assessment Of Gametes [ 6 ] -- FERTILIZATION [ 7 ] -- PREIMPLANTATION DEVELOPMENT [ 8 ] -- Metabolic Substrates And Pathways -- Gene Expression In Early Embryonic Development -- Regulative Potential Of Micromanipulated Embryos -- IMPLANTATION [ 9 ] -- ENDNOTES -- Chapter 3 Barriers To Progress In In Vitro Fertilization And Embryo Transfer. ETHICAL AND SOCIAL ISSUES -- The Federal Government And Embryo Research -- Domestic And Foreign Decisions On Embryo Research -- OTHER BARRIERS TO SCIENTIFIC PROGRESS -- Deficiencies In The Science Base -- Research Funding -- Lack Of Communication Among Researchers -- Societal Concerns -- Sources Of Research Material -- REFERENCES -- Chapter 4 Research Agenda And Recommendations -- RESEARCH AGENDA -- Basic Science -- Male Gametogenesis -- Female Gametogenesis -- Fertilization -- Preimplantation Development -- Implantation -- Technological Advances -- Clinical Research Opportunities -- CONCLUSIONS AND RECOMMENDATIONS -- Developing Research Policy -- Basic Science Foundations -- Applied Research -- Clinical Research Opportunities -- Improving Communications -- Appendix A Committee On Basic Science Foundations Of Medically Assisted Conception -- TECHNOLOGIES FOR ASSISTED CONCEPTION/EMBRYO TRANSFER IN AGRICULTURAL AND VETERINARY PRACTICE -- Introduction -- Artificial Insemination -- Superovulation -- Embryo Transfer -- Freezing Of Embryos -- Sexing Of Embryos -- Sexing By Y Chromosome Specific Dna Hybridization -- Multiplication Of Embryos -- Nuclear Transfer -- In Vitro Production Of Embryos -- Oocyte Maturation -- In Vitro Fertilization -- Development Of Embryos In Vitro -- Gene Transfer -- Conclusions -- References -- OVARIAN STIMULATION IN NON-HUMAN PRIMATES -- Introduction -- The Menstrual Cycle -- Regulation Of Folliculogenesis -- Ovarian Stimulation -- Problems With Stimulated Ovarian Function -- Solutions For Problems With Stimulated Ovarian Function -- Acknowledgement -- References -- RESPONSES TO GONADOTROPINS IN DOMESTIC ANIMALS -- Introduction -- Superovulation In Domestic Animals -- Superovulation Of Cattle -- Superovulation Of Sheep And Goats -- Effects Of Exogenous Gonadotropins On Horses -- Ovulation Induction In Pigs. Recommendations For Future Directions In Research -- Summary -- References -- MEMBRANE MODELS: EVOLUTION FROM THE FLUID-MOSAIC STANDBY ROY HAMMERSTEDT -- Introduction -- Complexity Of The Cell Surface -- Asymmetry Of Cell Surfaces -- Lipid Domains -- Relative Speed Of Membrane Events -- Spatial Relationships On The Membrane Surface -- Summary -- Acknowledgements -- References -- MAMMALIAN OOCYTE MATURATION: MECHANISMS FOR REGULATION AND PROSPECTS FOR PRACTICAL APPLICATION OF IN VITRO TECHNOLOGY -- The Ovarian Follicle As The Support System For Oocyte Development In Vivo -- Identification Of Molecules And Pathways That Participate In The Maintenance Of Meiotic Arrest -- Induction Of Oocyte Maturation -- Similarities Between Mechanisms That Govern Meiotic and Mitotic Cell Division -- Murine Oocyte Growth And Development In Culture -- Prospects For The Practical Utilization Of Oocyte Culture Systems -- Expansion Of Populations Of Rare Or Agriculturally Important Mammals -- Acknowledgments -- References -- INTRAGONADAL CONTROL OF TESTIS FUNCTION -- Introduction -- Summary And Conclusions -- References -- PARACRINE REGULATION IN THE OVARY -- Introduction -- Intraovarian Steroids -- The Role Of Ovarian Growth Factors -- Other Regulatory Peptides In The Ovarian Follicle -- Summary Of Current Efforts And Future Perspectives -- Acknowledgements -- Literature Cited -- EXPERIMENTAL APPROACHES TO THE STUDY OF EARLY DEVELOPMENTAL FAILURE IN HUMAN REPRODUCTION -- Early Developmental Failure In The Human -- The Frequency Of Chromosomal Anomalies In Human Oocytes After Ovarian Hyperstimulation -- Developmental Failure During The Perifertilization Period -- Summary -- Acknowledgement -- References -- Figure Legends -- THE FERTILIZING SPERM: STRUCTURE, MATURATION AND FUNCTION -- Introduction -- Sperm Structure. Common Themes In The Cellular Sequence Of Gamete Interaction -- A General Model For Mammallan Gamete Interaction -- Common Themes During Epididymal Transit -- For What Types Of Studies Are Model Systems Appropriate? -- Summary -- Reviews to consult for detailed information and references -- MOLECULAR EVENTS PRE-AND POST-FERTILIZATION OF MOUSE EGGS: OOCYTE MATURATION, EGG ACTIVATION, AND POLYSPERMY BLOCK -- Introduction -- Acquisition Of Meiotic Competence -- Oocyte Maturation -- 1. Role Of Camp And Protein Phosphorylation -- 2. Maturation Promoting Factor -- 3. Acquisition And Maintenance Of Sperm Decondensing Activity -- Fertilization And Egg Activation -- 1. Block To Polyspermy -- Unresolved Questions And Future Directions -- Acknowledgements -- References -- GLYCOLYTIC PATHWAY IN PREIMPLANTATION MAMMALIAN EMBRYOS -- Introduction -- Evidence That Metabolic Pathways Are Respricted In Oogenesis And Early Mammalian Development -- Morphology Of The Mitochondria During Oogenesis And Preimplantation Development -- Nutritional Studies With Chemically Defined Media -- Uptake Of Metabolic Substrates -- Metabolic Fate Of Substrates -- A Caveat-Be Alert For Artifacts -- Metabolic Fate Of Glucose -- Control Of Glycolysis -- Conclusion -- References -- REGULATIVE POTENTLAL OF MICROMANIPULATED EMBRYOS -- Introduction -- Uses Of Micromanipulation -- Types Of Manipulation -- Regulation In Mammalian Embryos -- Use Of Micromanipulation In Studying Regulation In Laboratory And Domestic Species -- Preimplantation Development -- Regulation And Cell Potential During Cleavage And Blastulation -- How Is Relation Accomplished? -- References -- UTERINE RECEPTIVITY, MATERNAL RECOGNITION OF PREGNANCY AND EARLY EMBRYONIC LOSS -- Summary -- Magnitude Of Embryonic Losses -- Causes Of Embryonic Loss -- Implantation And Placentation. Asynchrony Of Embryo And Mother Is Related To Early Embryonic Loss -- The Necessity Of The Uterine Environment -- Maternal Recognition Of Pregnancy And Pregnancy Failure -- Immunological Rejection Of Embryos -- Natural Asynchrony And Embryonic Loss -- References -- Legend to Figure -- TOWARDS A CELLULAR AND MOLECULAR UNDERSTANDING OF IMPLANTATION IN THE HUMAN: IMPLICATIONS FOR ASSISTED REPRODUCTIVE... -- Introduction -- Preparation And Characterization Of Human Cytotrophoblasts -- Trophoblast Aggregation -- Trophoblast Fusion -- Trophoblast Interactions With Extracellular Matrix -- Relationship Between Morphologic And Functional Differentiation Of The Trophoblast -- Interactions Between Trophoblast And Endometrium -- Cytotrophoblast Interactions With Endometrial Explants -- Cytotrophoblast Interactions With Endometrial Glandular Epithelium And Stroma -- Trophoblast Invasion Into The Endometrium -- Paracrine Interactions During Implantation -- A Working Model For Implantation In The Human And Future Directions For Research -- Acknowledgements -- References. Fertilization in vitro. http://id.loc.gov/authorities/subjects/sh85047905 Fertilization in vitro, Human. http://id.loc.gov/authorities/subjects/sh85047906 Reproductive technology. http://id.loc.gov/authorities/subjects/sh88005586 Artificial insemination. http://id.loc.gov/authorities/subjects/sh85008174 Human reproductive technology. http://id.loc.gov/authorities/subjects/sh88005587 Embryo transplantation. http://id.loc.gov/authorities/subjects/sh85042720 Research. http://id.loc.gov/authorities/subjects/sh85113021 Risk. http://id.loc.gov/authorities/subjects/sh85114195 Risk assessment. http://id.loc.gov/authorities/subjects/sh87002638 Agriculture. http://id.loc.gov/authorities/subjects/sh85002415 Animal experimentation. http://id.loc.gov/authorities/subjects/sh85005173 Contraception. http://id.loc.gov/authorities/subjects/sh85031589 Federal government. http://id.loc.gov/authorities/subjects/sh85047611 Goal (Psychology) http://id.loc.gov/authorities/subjects/sh85055484 Political science. http://id.loc.gov/authorities/subjects/sh85104440 Politics, Practical. http://id.loc.gov/authorities/subjects/sh85104466 Infertility. http://id.loc.gov/authorities/subjects/sh85066087 International cooperation. http://id.loc.gov/authorities/subjects/sh85067385 Methodology. http://id.loc.gov/authorities/subjects/sh85084414 Sex preselection. http://id.loc.gov/authorities/subjects/sh85120660 Social control. http://id.loc.gov/authorities/subjects/sh85123931 Embryo Transfer Fertilization in Vitro Embryo Research Embryo, Mammalian Research Risk Risk Assessment Technology Assessment, Biomedical Insemination, Artificial https://id.nlm.nih.gov/mesh/D007315 Reproductive Techniques, Assisted https://id.nlm.nih.gov/mesh/D027724 Reproductive Techniques Agriculture Animal Experimentation Animal Welfare Biomedical Research Contraception Federal Government Financial Support Goals Government Government Regulation Infertility International Cooperation Internationality Methods Public Policy Sex Preselection Social Control, Formal Fécondation in vitro. Reproduction Innovations. Insémination artificielle. Procréation médicalement assistée. Embryons Transplantation. Recherche. Risque. Évaluation du risque. Agriculture. Expérimentation animale. Contraception. Gouvernement fédéral. But (Psychologie) Institutions politiques. Infertilité. Coopération internationale. Méthodologie. Sexe des enfants Choix. Contrôle social. research (function) aat risk assessment. aat farming (activity or system) aat federal government. aat governments (administrative bodies) aat methodology. aat agriculture (discipline) aat HEALTH & FITNESS Infertility. bisacsh Social control fast Sex preselection fast Risk assessment fast Risk fast Research fast Politics, Practical fast Political science fast Methodology fast International cooperation fast Infertility fast Goal (Psychology) fast Federal government fast Embryo transplantation fast Contraception fast Animal experimentation fast Agriculture fast Artificial insemination fast Fertilization in vitro fast Fertilization in vitro, Human fast Human reproductive technology fast Reproductive technology fast
subject_GND	http://id.loc.gov/authorities/subjects/sh85047905 http://id.loc.gov/authorities/subjects/sh85047906 http://id.loc.gov/authorities/subjects/sh88005586 http://id.loc.gov/authorities/subjects/sh85008174 http://id.loc.gov/authorities/subjects/sh88005587 http://id.loc.gov/authorities/subjects/sh85042720 http://id.loc.gov/authorities/subjects/sh85113021 http://id.loc.gov/authorities/subjects/sh85114195 http://id.loc.gov/authorities/subjects/sh87002638 http://id.loc.gov/authorities/subjects/sh85002415 http://id.loc.gov/authorities/subjects/sh85005173 http://id.loc.gov/authorities/subjects/sh85031589 http://id.loc.gov/authorities/subjects/sh85047611 http://id.loc.gov/authorities/subjects/sh85055484 http://id.loc.gov/authorities/subjects/sh85104440 http://id.loc.gov/authorities/subjects/sh85104466 http://id.loc.gov/authorities/subjects/sh85066087 http://id.loc.gov/authorities/subjects/sh85067385 http://id.loc.gov/authorities/subjects/sh85084414 http://id.loc.gov/authorities/subjects/sh85120660 http://id.loc.gov/authorities/subjects/sh85123931 https://id.nlm.nih.gov/mesh/D007315 https://id.nlm.nih.gov/mesh/D027724
title	Medically assisted conception : an agenda for research : report of a study /
title_auth	Medically assisted conception : an agenda for research : report of a study /
title_exact_search	Medically assisted conception : an agenda for research : report of a study /
title_full	Medically assisted conception : an agenda for research : report of a study / by a committee of the Institute of Medicine, Division of Health Sciences Policy, National Research Council, Board on Agriculture.
title_fullStr	Medically assisted conception : an agenda for research : report of a study / by a committee of the Institute of Medicine, Division of Health Sciences Policy, National Research Council, Board on Agriculture.
title_full_unstemmed	Medically assisted conception : an agenda for research : report of a study / by a committee of the Institute of Medicine, Division of Health Sciences Policy, National Research Council, Board on Agriculture.
title_short	Medically assisted conception :
title_sort	medically assisted conception an agenda for research report of a study
title_sub	an agenda for research : report of a study /
topic	Fertilization in vitro. http://id.loc.gov/authorities/subjects/sh85047905 Fertilization in vitro, Human. http://id.loc.gov/authorities/subjects/sh85047906 Reproductive technology. http://id.loc.gov/authorities/subjects/sh88005586 Artificial insemination. http://id.loc.gov/authorities/subjects/sh85008174 Human reproductive technology. http://id.loc.gov/authorities/subjects/sh88005587 Embryo transplantation. http://id.loc.gov/authorities/subjects/sh85042720 Research. http://id.loc.gov/authorities/subjects/sh85113021 Risk. http://id.loc.gov/authorities/subjects/sh85114195 Risk assessment. http://id.loc.gov/authorities/subjects/sh87002638 Agriculture. http://id.loc.gov/authorities/subjects/sh85002415 Animal experimentation. http://id.loc.gov/authorities/subjects/sh85005173 Contraception. http://id.loc.gov/authorities/subjects/sh85031589 Federal government. http://id.loc.gov/authorities/subjects/sh85047611 Goal (Psychology) http://id.loc.gov/authorities/subjects/sh85055484 Political science. http://id.loc.gov/authorities/subjects/sh85104440 Politics, Practical. http://id.loc.gov/authorities/subjects/sh85104466 Infertility. http://id.loc.gov/authorities/subjects/sh85066087 International cooperation. http://id.loc.gov/authorities/subjects/sh85067385 Methodology. http://id.loc.gov/authorities/subjects/sh85084414 Sex preselection. http://id.loc.gov/authorities/subjects/sh85120660 Social control. http://id.loc.gov/authorities/subjects/sh85123931 Embryo Transfer Fertilization in Vitro Embryo Research Embryo, Mammalian Research Risk Risk Assessment Technology Assessment, Biomedical Insemination, Artificial https://id.nlm.nih.gov/mesh/D007315 Reproductive Techniques, Assisted https://id.nlm.nih.gov/mesh/D027724 Reproductive Techniques Agriculture Animal Experimentation Animal Welfare Biomedical Research Contraception Federal Government Financial Support Goals Government Government Regulation Infertility International Cooperation Internationality Methods Public Policy Sex Preselection Social Control, Formal Fécondation in vitro. Reproduction Innovations. Insémination artificielle. Procréation médicalement assistée. Embryons Transplantation. Recherche. Risque. Évaluation du risque. Agriculture. Expérimentation animale. Contraception. Gouvernement fédéral. But (Psychologie) Institutions politiques. Infertilité. Coopération internationale. Méthodologie. Sexe des enfants Choix. Contrôle social. research (function) aat risk assessment. aat farming (activity or system) aat federal government. aat governments (administrative bodies) aat methodology. aat agriculture (discipline) aat HEALTH & FITNESS Infertility. bisacsh Social control fast Sex preselection fast Risk assessment fast Risk fast Research fast Politics, Practical fast Political science fast Methodology fast International cooperation fast Infertility fast Goal (Psychology) fast Federal government fast Embryo transplantation fast Contraception fast Animal experimentation fast Agriculture fast Artificial insemination fast Fertilization in vitro fast Fertilization in vitro, Human fast Human reproductive technology fast Reproductive technology fast
topic_facet	Fertilization in vitro. Fertilization in vitro, Human. Reproductive technology. Artificial insemination. Human reproductive technology. Embryo transplantation. Research. Risk. Risk assessment. Agriculture. Animal experimentation. Contraception. Federal government. Goal (Psychology) Political science. Politics, Practical. Infertility. International cooperation. Methodology. Sex preselection. Social control. Embryo Transfer Fertilization in Vitro Embryo Research Embryo, Mammalian Research Risk Risk Assessment Technology Assessment, Biomedical Insemination, Artificial Reproductive Techniques, Assisted Reproductive Techniques Agriculture Animal Experimentation Animal Welfare Biomedical Research Contraception Federal Government Financial Support Goals Government Government Regulation Infertility International Cooperation Internationality Methods Public Policy Sex Preselection Social Control, Formal United States Fécondation in vitro. Reproduction Innovations. Insémination artificielle. Procréation médicalement assistée. Embryons Transplantation. Recherche. Risque. Évaluation du risque. Expérimentation animale. Gouvernement fédéral. But (Psychologie) Institutions politiques. Infertilité. Coopération internationale. Méthodologie. Sexe des enfants Choix. Contrôle social. research (function) risk assessment. farming (activity or system) federal government. governments (administrative bodies) methodology. agriculture (discipline) HEALTH & FITNESS Infertility. Social control Sex preselection Risk assessment Politics, Practical Political science Methodology International cooperation Federal government Embryo transplantation Animal experimentation Artificial insemination Fertilization in vitro Fertilization in vitro, Human Human reproductive technology Reproductive technology
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work_keys_str_mv	AT committeeonthebasicsciencefoundationsofmedicallyassistedconception medicallyassistedconceptionanagendaforresearchreportofastudy AT ryankennethj medicallyassistedconceptionanagendaforresearchreportofastudy AT instituteofmedicineusdivisionofhealthsciencespolicy medicallyassistedconceptionanagendaforresearchreportofastudy AT nationalresearchcouncilusboardonagriculture medicallyassistedconceptionanagendaforresearchreportofastudy

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