Verfügbarkeit: Behavioral measures of neurotoxicity :

Behavioral measures of neurotoxicity :: report of a symposium /

Gespeichert in:

Bibliographische Detailangaben
Körperschaften:	U.S. National Committee for the International Union of Psychological Science, National Research Council (U.S.). Commission on Behavioral and Social Sciences and Education, National Research Council (U.S.), Workshop on Behavioral Aspects of Neurotoxicity: Critical Issues
Weitere Verfasser:	Russell, Roger W., Flattau, Pamela Ebert, Pope, Andrew MacPherson, 1950-
Format:	Regierungsdokument Elektronisch Tagungsbericht E-Book
Sprache:	English
Veröffentlicht:	Washington, D.C. : National Academy Press, 1990.
Schlagworte:	Neurotoxicology > Congresses. Behavioral toxicology > Congresses. Nervous system > Diseases > Environmental aspects > Congresses. Neuropsychological tests > Congresses. Diseases. Nervous system > Diseases. Neurotoxic agents. Human behavior. Environmental toxicology > Congresses. Disease Behavior and Behavior Mechanisms Noxae Publication Formats Psychiatry and Psychology Publication Characteristics Toxic Actions Chemical Actions and Uses Chemicals and Drugs Nervous System Diseases Neurotoxins Behavior Congresses Neurotoxicologie > Congrès. Écotoxicologie > Congrès. Système nerveux > Maladies > Aspect de l'environnement > Congrès. Tests neuropsychologiques > Congrès. Toxicologie du comportement > Congrès. Maladies. Système nerveux > Maladies. Neurotoxines. Comportement humain. human behavior. HEALTH & FITNESS > Diseases > Nervous System (incl. Brain) MEDICAL > Neurology. Neurotoxic agents Nervous system > Diseases Human behavior Environmental toxicology Diseases Behavioral toxicology Neuropsychological tests Neurotoxicology Umweltchemikalie Neurotoxizität Verhaltenstest Kongress Nervengift Toxizitätstest Congress proceedings (reports) Conference papers and proceedings Conference papers and proceedings. Actes de congrès.
Online-Zugang:	Volltext
Beschreibung:	"[Sponsored by] U.S. National Committee for the International Union of Psychological Science, Commission on Behavioral and Social Sciences and Education, National Research Council." Based on the Workshop on Behavioral Aspects of Neurotoxicity, Critical Issues, held in Aug. 1988 at the Australian National University in Canberra.
Beschreibung:	1 online resource (xiii, 432 pages) : illustrations
Format:	Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Bibliographie:	Includes bibliographical references and index.
ISBN:	0585148937 9780585148939 1280214503 9781280214509 9786610214501 6610214506 0309559650 9780309559652

Internformat

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245	0	0	\|a Behavioral measures of neurotoxicity : \|b report of a symposium / \|c Roger W. Russell, Pamela Ebert Flattau, and Andrew M. Pope, editors.
260			\|a Washington, D.C. : \|b National Academy Press, \|c 1990.
300			\|a 1 online resource (xiii, 432 pages) : \|b illustrations
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500			\|a Based on the Workshop on Behavioral Aspects of Neurotoxicity, Critical Issues, held in Aug. 1988 at the Australian National University in Canberra.
504			\|a Includes bibliographical references and index.
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546			\|a English.
505	0		\|a Behavioral Measures of Neurotoxicity -- Copyright -- SYMPOSIUM CONTRIBUTORS -- PREFACE -- Contents -- INTRODUCTION -- IDENTIFICATION OF BEHAVIORAL TOXIC AGENTS -- MECHANISMS AND SITES OF ACTION -- THE MEASUREMENT OF BEHAVIOR -- THE LIFE SPAN: WHEN TO MEASURE? -- APPROACHES TO RESEARCH -- REGIONAL REQUIREMENTS -- COMMUNICATION -- CONCLUSION -- REFERENCES -- ARE NEUROTOXINS DRIVING US CRAZY? PLANETARY OBSERVATIONS ON THE CAUSES OF NEURODEGENERATIVE DISEASES OF OLD AGE -- CLINICAL FEATURES OF WESTERN PACIFIC ALS/P-D -- WHAT IS THE CAUSE OF WESTERN PACIFIC ALS/P-D? -- CYCADS: POISONOUS PLANTS USED FOR MEDICINE AND FOOD -- FROM LATHYRISM TO CYCADISM -- LINKING CYCADS TO ALS IN IRIAN JAYA AND JAPAN -- TIMING OF CYCAD EXPOSURE -- RELEVANCE FOR VETERANS OF THE PACIFIC WAR -- TOXIC COMPONENTS OF CYCADS -- SUMMARY -- REFERENCES -- PART I ASSESSMENT OF NEUROBEHAVIORAL TESTS NOW IN USE -- Methods in Behavioral Toxicology: Current Test Batteries and Need for Development -- TEST BATTERIES NOW IN USE -- Epidemiological and Field Studies -- BEHAVIORAL TOXICOLOGY IN CLINICAL PRACTICE -- BASES OF TEST SELECTION -- THE NEUROBEHAVIORAL CORE TEST BATTERY -- FUTURE DIRECTIONS: SOME CRUCIAL ISSUES -- Neuropsychological Description/Definition of Neurotoxic Syndrome(s) -- Natural History of the Neurotoxic Effects -- Dilemma Between Conservative and Progressive Approaches -- Further Questions of Test Selection -- Simple or Complex Tasks? -- Reliability of Tests and Stability of Functions -- Changes in Personality, Mood, and Affect -- Other Areas for Method Development -- SUMMARY -- References -- The Current Status of Test Development in Neurobehavioral Toxicology -- RESEARCH DESIGN AND TEST SELECTION -- REASONS FOR TEST SELECTION -- RECENT APPROACHES TO TEST BATTERY DESIGN -- Neurobehavioral Core Test Battery -- The Computerized Battery Approach.
505	8		\|a Model or Theory-Based Tests and Test Batteries -- INFLUENCE ON TESTING SELECTION OF DIFFERENT OBJECTIVES FOR TESTING -- EXPECTED DIRECTIONS IN TEST DEVELOPMENT -- REMAINING BARRIERS TO TEST DEVELOPMENT -- RECOMMENDATIONS FOR FURTHER RESEARCH OR DEVELOPMENT -- References -- Human Neurobehavioral Toxicology Testing -- RATIONALES FOR DEVELOPING TEST BATTERIES -- Finland's Institute of Occupational Health Approach -- Problem-Based Approach -- Approach Recommended by the World Health Organization -- Neurobehavioral Evaluation System Approach -- TARGET ORGAN EFFECTS -- Neurotoxic Chemicals -- Exposure Populations -- Behaviors Affected by Many Chemicals -- NIOSH Recommendations -- Recommendations of the American Conference of Governmental Industrial Hygienists -- POTENTIAL OF TEST BATTERIES TO ASSESS TARGET ORGAN HEALTH EFFECTS -- DEVELOPMENT EFFORTS UNDER WAY -- NOTES -- ACKNOWLEDGMENT AND DISCLAIMER -- References -- Neurobehavioral Tests: Problems, Potential, and Prospects -- TESTS CURRENTLY IN USE -- SOME SPECIFIC POINTS -- Methods in Behavioral Toxicology (Hanninen) -- Current Status of Test Development (Williamson) -- Human Neurobehavioral Tests (Anger) -- THE ADEQUACY OF CURRENT TESTS -- SOME NEW DEVELOPMENTS IN COMPUTER-BASED ASSESSMENT -- Cognitive Componential Models -- Inferential Systems -- IMPLICATIONS FOR NEUROBEHAVIORAL ASSESSMENT -- References -- PART II ASSESSMENT OF ANIMAL MODELS: WHAT HAS WORKED AND WHAT IS NEEDED -- Exposure to Neurotoxins Throughout the Life Span: Animal Models for Linking Neurochemical Effects to Behavioral Consequences -- NEUROCHEMICAL CHANGES DURING DEVELOPMENT AND AGING -- THE CHOLINERGIC SYSTEM IN BEHAVIOR -- EFFECTS OF PRENATAL EXPOSURE TO DFP: FROM BIRTH TO WEANING -- EFFECTS OF EARLY POSTNATAL EXPOSURE TO DFP -- EFFECTS OF EXPOSURE TO DFP: SENESCENT RATS -- Genetic (Strain-Specific) Differences in Effects.
505	8		\|a Subchronic Intoxication During Senescence -- Time-Course Recovery of mAChRs Following Down-Regulation in Brain of Senescent Rats -- CONCLUSION -- References -- Animal Models of Dementia: Their Relevance to Neurobehavioral Toxicology Testing -- ANIMAL MODELS OF DEMENTIA -- ENVIRONMENTAL CHALLENGES -- PHARMACOLOGICAL CHALLENGES -- MEASURING BEHAVIORAL EFFECTS: SPECIFIC PARADIGMS -- Inhibitory (Passive) Avoidance -- Active Avoidance Tasks -- Operant Conditioning -- Maze Learning -- Other Measures -- CONCLUSION -- ACKNOWLEDGMENTS -- References -- Bridging Experimental Animal and Human Behavioral Toxicology Studies -- THE SCOPE AND AGENDA OF BEHAVIORAL TOXICOLOGY -- STATE OF DEVELOPMENT -- BARRIERS TO ADVANCEMENT -- ACCELERATING THE PACE -- References -- Methods and Issues in Evaluating the Neurotoxic Effects of Organic Solvents -- ACUTE SOLVENT EFFECTS -- APPLICATION OF ANIMAL BEHAVIORAL METHODS -- Acute Effects of Single Exposures -- Acute Effects in the Context of Chronic Exposures -- Reinforcing Properties of Organic Solvents -- CHRONIC SOLVENT EFFECTS ON THE PERIPHERAL NERVOUS SYSTEM -- The Role of Animal Studies -- Neurobehavioral Methods for Screening Sensory and Motor Effects -- Problems in the Interpretation of Human Studies -- Animal Models of Cognitive Effects -- REFERENCES -- Animal Models: What Has Worked and What Is Needed -- References -- PART III CHEMICAL TIME BOMBS: ENVIRONMENTAL CAUSES OF NEURODEGENERATIVE DISEASES -- On the Identification and Measurement of Chemical Time Bombs: A Behavior Development Perspective -- METHODOLOGICAL CONSIDERATIONS -- APPROACHES TO DETECTING BEHAVIORALLY TOXIC SUBSTANCES -- A POTENTIAL TIME BOMB? -- NEW METHODS FOR MEASURING BEHAVIORAL TOXICITY -- ADDITIONAL APPROACHES AND NEW DIRECTIONS -- Multiple Behaviors Can Be Studied -- Comparative Developmental Studies Can Be Undertaken.
505	8		\|a Knowledge Concerning Neurocircuitry and Neurochemistry of the Response Is Accumulating -- ACKNOWLEDGMENT -- References -- Neurobehavioral Time Bombs: Their Nature and Their Mechanisms -- Relations Between Behavior and Chemical Environment -- CHOLINESTERASE IN PROGRESSIVE DEGENERATIVE DEMENTIAS -- Preclinical Studies of Acetylcholinesterase and Behavior -- Acetylcholinesterase in Behavioral Disorders -- THE TRUTH ABOUT A FALSE TRANSMITTER -- NEUROTROPHIC FACTORS AND BEHAVIOR -- Neurotrophic Factors -- Neurotrophic Factors and Their Environments -- Roles During Neuronal Development and Beyond -- Recovery from Morphological Lesions -- Brain Transplants -- Nerve Growth Factor, Brain Implants, and Behavior -- Behavioral Recovery from Brain Lesions -- CONTRIBUTIONS IN THE FUTURE -- NOTE -- References -- Neurobehavioral Toxicity of Selected Environmental Chemicals: Clinical and Subclinical Aspects -- CLINICAL VERSUS SUBCLINICAL NEUROTOXICITY -- NEUROBEHAVIORAL EFFECTS OF SELECTED INDUSTRIAL CHEMICALS -- Effects in the Developing Nervous System -- Lead -- Mercury -- Polychlorinated Biphenyls -- EFFECTS IN THE ADULT NERVOUS SYSTEM -- Aluminum -- Organic Solvents -- CONCLUSION -- Lack of Consistency -- Lack of Developmental Perspective -- Uncertain Health Significance -- References -- The Health Effects of Environmental Lead Exposure: Closing Pandora's Box -- HISTORY OF THE PRESENT PERSPECTIVE ON THE ENVIRONMENTAL NEUROTOXICITY OF LEAD -- OVERVIEW OF MODERN STUDIES -- Prospective Studies -- Reproductive Effects -- Early Behavioral Effects of Perinatal Lead Exposure -- Retrospective Studies on Correlation of Lead Body Burden and Behavior in Grade School Children -- Later Behavioral Concomitants of Increased Lead Burden -- Effects of Lead on Other Neuropsychological Endpoints -- Other Health Effects of Environmental Lead Exposure -- CRITICAL ISSUES.
505	8		\|a Markers of Lead Exposure -- Statistical Interpretation -- Adequacy of Behavioral Methodology -- Does Lead Contribute to Aging? -- Overview of Cost to Society -- Have Regulatory Agencies Been Slow to Act? -- CLOSING PANDORA'S BOX -- References -- Chemical Time Bombs: Environmental Causes of Neurodegenerative Diseases -- ESTABLISHING CRITERIA FOR CHEMICAL NEUROTOXICITY -- CLASSIFYING CHEMICALLY INDUCED HUMAN NEUROTOXIC DISORDERS -- THE MATURE NERVOUS SYSTEM AS CHEMICAL TARGET -- DEVELOPING NERVOUS SYSTEM AS CHEMICAL TARGET -- Scientific Basis for Neurobehavioral Toxicity Testing -- CONCLUSION -- Reference -- PART IV BEHAVIORAL ASPECTS OF NEUROTOXICITY: REGIONAL ISSUES -- Neurobehavioral Toxicity Testing in China -- INTRODUCTION -- OVERVIEW OF RESEARCH ACTIVITIES -- Carbon Disulfide -- Lead -- Simulated Video Display Terminal (VDT) Operation -- Static Magnetic Fields (SMF) -- NATIONAL AND INTERNATIONAL COOPERATION -- Mood States -- Performance Tests -- EXPECTED DIRECTIONS: BARRIERS AND RECOMMENDATIONS -- Developments in the Near Future -- Developing and Validating Test Methods -- Generating New Measuring Instruments -- Building a Computerized Evaluation System -- Limitations and Barriers -- Variation of Test Sensitivity from Study to Study -- Bias of Learning Effect -- Controlling Confounding Factors -- Interpreting Results Obtained from Neurobehavioral Tests -- Comments and Recommendations -- Training and Education -- Exploring the Possibility of Combining Quantitative Biochemical Markers and Neurobehavioral Testing -- Development, Validation, and Characterization of Methods -- SUMMARY -- Status of Research and Development of Neurobehavioral Toxicity Tests in China -- Expected Directions in the Development of Behavioral Tests of Neurotoxicity -- Problems and Recommendations -- References.
650		0	\|a Neurotoxicology \|v Congresses.
650		0	\|a Behavioral toxicology \|v Congresses.
650		0	\|a Nervous system \|x Diseases \|x Environmental aspects \|v Congresses.
650		0	\|a Neuropsychological tests \|v Congresses.
650		0	\|a Diseases. \|0 http://id.loc.gov/authorities/subjects/sh85038411
650		0	\|a Nervous system \|x Diseases. \|0 http://id.loc.gov/authorities/subjects/sh85090924
650		0	\|a Neurotoxic agents. \|0 http://id.loc.gov/authorities/subjects/sh85091181
650		0	\|a Human behavior. \|0 http://id.loc.gov/authorities/subjects/sh85062839
650		0	\|a Environmental toxicology \|v Congresses.
650		0	\|a Nervous system \|x Diseases \|x Environmental aspects \|x Congresses.
650		0	\|a Neuropsychological tests \|x Congresses.
650		2	\|a Disease
650		2	\|a Behavior and Behavior Mechanisms
650		2	\|a Noxae
650		2	\|a Publication Formats
650		2	\|a Psychiatry and Psychology
650		2	\|a Publication Characteristics
650		2	\|a Toxic Actions
650		2	\|a Chemical Actions and Uses
650		2	\|a Chemicals and Drugs
650		2	\|a Nervous System Diseases
650		2	\|a Neurotoxins
650		2	\|a Behavior
650		2	\|a Congresses
650		6	\|a Neurotoxicologie \|v Congrès.
650		6	\|a Écotoxicologie \|v Congrès.
650		6	\|a Système nerveux \|x Maladies \|x Aspect de l'environnement \|x Congrès.
650		6	\|a Tests neuropsychologiques \|x Congrès.
650		6	\|a Toxicologie du comportement \|v Congrès.
650		6	\|a Système nerveux \|x Maladies \|x Aspect de l'environnement \|v Congrès.
650		6	\|a Tests neuropsychologiques \|v Congrès.
650		6	\|a Maladies.
650		6	\|a Système nerveux \|x Maladies.
650		6	\|a Neurotoxines.
650		6	\|a Comportement humain.
650		7	\|a human behavior. \|2 aat
650		7	\|a HEALTH & FITNESS \|x Diseases \|x Nervous System (incl. Brain) \|2 bisacsh
650		7	\|a MEDICAL \|x Neurology. \|2 bisacsh
650		7	\|a Neurotoxic agents \|2 fast
650		7	\|a Nervous system \|x Diseases \|2 fast
650		7	\|a Human behavior \|2 fast
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650		7	\|a Diseases \|2 fast
650		7	\|a Behavioral toxicology \|2 fast
650		7	\|a Neuropsychological tests \|2 fast
650		7	\|a Neurotoxicology \|2 fast
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655		2	\|a Congress
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655		7	\|a Actes de congrès. \|2 rvmgf
700	1		\|a Russell, Roger W.
700	1		\|a Flattau, Pamela Ebert.
700	1		\|a Pope, Andrew MacPherson, \|d 1950- \|1 https://id.oclc.org/worldcat/entity/E39PCjFyR4RCKGhy6Bf8DXWRXb \|0 http://id.loc.gov/authorities/names/n87820748
710	2		\|a U.S. National Committee for the International Union of Psychological Science. \|0 http://id.loc.gov/authorities/names/n88290637
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710	2		\|a National Research Council (U.S.) \|0 http://id.loc.gov/authorities/names/n79036113
711	2		\|a Workshop on Behavioral Aspects of Neurotoxicity: Critical Issues \|d (1988 : \|c Australian National University) \|0 http://id.loc.gov/authorities/names/n88290636
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contents	Behavioral Measures of Neurotoxicity -- Copyright -- SYMPOSIUM CONTRIBUTORS -- PREFACE -- Contents -- INTRODUCTION -- IDENTIFICATION OF BEHAVIORAL TOXIC AGENTS -- MECHANISMS AND SITES OF ACTION -- THE MEASUREMENT OF BEHAVIOR -- THE LIFE SPAN: WHEN TO MEASURE? -- APPROACHES TO RESEARCH -- REGIONAL REQUIREMENTS -- COMMUNICATION -- CONCLUSION -- REFERENCES -- ARE NEUROTOXINS DRIVING US CRAZY? PLANETARY OBSERVATIONS ON THE CAUSES OF NEURODEGENERATIVE DISEASES OF OLD AGE -- CLINICAL FEATURES OF WESTERN PACIFIC ALS/P-D -- WHAT IS THE CAUSE OF WESTERN PACIFIC ALS/P-D? -- CYCADS: POISONOUS PLANTS USED FOR MEDICINE AND FOOD -- FROM LATHYRISM TO CYCADISM -- LINKING CYCADS TO ALS IN IRIAN JAYA AND JAPAN -- TIMING OF CYCAD EXPOSURE -- RELEVANCE FOR VETERANS OF THE PACIFIC WAR -- TOXIC COMPONENTS OF CYCADS -- SUMMARY -- REFERENCES -- PART I ASSESSMENT OF NEUROBEHAVIORAL TESTS NOW IN USE -- Methods in Behavioral Toxicology: Current Test Batteries and Need for Development -- TEST BATTERIES NOW IN USE -- Epidemiological and Field Studies -- BEHAVIORAL TOXICOLOGY IN CLINICAL PRACTICE -- BASES OF TEST SELECTION -- THE NEUROBEHAVIORAL CORE TEST BATTERY -- FUTURE DIRECTIONS: SOME CRUCIAL ISSUES -- Neuropsychological Description/Definition of Neurotoxic Syndrome(s) -- Natural History of the Neurotoxic Effects -- Dilemma Between Conservative and Progressive Approaches -- Further Questions of Test Selection -- Simple or Complex Tasks? -- Reliability of Tests and Stability of Functions -- Changes in Personality, Mood, and Affect -- Other Areas for Method Development -- SUMMARY -- References -- The Current Status of Test Development in Neurobehavioral Toxicology -- RESEARCH DESIGN AND TEST SELECTION -- REASONS FOR TEST SELECTION -- RECENT APPROACHES TO TEST BATTERY DESIGN -- Neurobehavioral Core Test Battery -- The Computerized Battery Approach. Model or Theory-Based Tests and Test Batteries -- INFLUENCE ON TESTING SELECTION OF DIFFERENT OBJECTIVES FOR TESTING -- EXPECTED DIRECTIONS IN TEST DEVELOPMENT -- REMAINING BARRIERS TO TEST DEVELOPMENT -- RECOMMENDATIONS FOR FURTHER RESEARCH OR DEVELOPMENT -- References -- Human Neurobehavioral Toxicology Testing -- RATIONALES FOR DEVELOPING TEST BATTERIES -- Finland's Institute of Occupational Health Approach -- Problem-Based Approach -- Approach Recommended by the World Health Organization -- Neurobehavioral Evaluation System Approach -- TARGET ORGAN EFFECTS -- Neurotoxic Chemicals -- Exposure Populations -- Behaviors Affected by Many Chemicals -- NIOSH Recommendations -- Recommendations of the American Conference of Governmental Industrial Hygienists -- POTENTIAL OF TEST BATTERIES TO ASSESS TARGET ORGAN HEALTH EFFECTS -- DEVELOPMENT EFFORTS UNDER WAY -- NOTES -- ACKNOWLEDGMENT AND DISCLAIMER -- References -- Neurobehavioral Tests: Problems, Potential, and Prospects -- TESTS CURRENTLY IN USE -- SOME SPECIFIC POINTS -- Methods in Behavioral Toxicology (Hanninen) -- Current Status of Test Development (Williamson) -- Human Neurobehavioral Tests (Anger) -- THE ADEQUACY OF CURRENT TESTS -- SOME NEW DEVELOPMENTS IN COMPUTER-BASED ASSESSMENT -- Cognitive Componential Models -- Inferential Systems -- IMPLICATIONS FOR NEUROBEHAVIORAL ASSESSMENT -- References -- PART II ASSESSMENT OF ANIMAL MODELS: WHAT HAS WORKED AND WHAT IS NEEDED -- Exposure to Neurotoxins Throughout the Life Span: Animal Models for Linking Neurochemical Effects to Behavioral Consequences -- NEUROCHEMICAL CHANGES DURING DEVELOPMENT AND AGING -- THE CHOLINERGIC SYSTEM IN BEHAVIOR -- EFFECTS OF PRENATAL EXPOSURE TO DFP: FROM BIRTH TO WEANING -- EFFECTS OF EARLY POSTNATAL EXPOSURE TO DFP -- EFFECTS OF EXPOSURE TO DFP: SENESCENT RATS -- Genetic (Strain-Specific) Differences in Effects. Subchronic Intoxication During Senescence -- Time-Course Recovery of mAChRs Following Down-Regulation in Brain of Senescent Rats -- CONCLUSION -- References -- Animal Models of Dementia: Their Relevance to Neurobehavioral Toxicology Testing -- ANIMAL MODELS OF DEMENTIA -- ENVIRONMENTAL CHALLENGES -- PHARMACOLOGICAL CHALLENGES -- MEASURING BEHAVIORAL EFFECTS: SPECIFIC PARADIGMS -- Inhibitory (Passive) Avoidance -- Active Avoidance Tasks -- Operant Conditioning -- Maze Learning -- Other Measures -- CONCLUSION -- ACKNOWLEDGMENTS -- References -- Bridging Experimental Animal and Human Behavioral Toxicology Studies -- THE SCOPE AND AGENDA OF BEHAVIORAL TOXICOLOGY -- STATE OF DEVELOPMENT -- BARRIERS TO ADVANCEMENT -- ACCELERATING THE PACE -- References -- Methods and Issues in Evaluating the Neurotoxic Effects of Organic Solvents -- ACUTE SOLVENT EFFECTS -- APPLICATION OF ANIMAL BEHAVIORAL METHODS -- Acute Effects of Single Exposures -- Acute Effects in the Context of Chronic Exposures -- Reinforcing Properties of Organic Solvents -- CHRONIC SOLVENT EFFECTS ON THE PERIPHERAL NERVOUS SYSTEM -- The Role of Animal Studies -- Neurobehavioral Methods for Screening Sensory and Motor Effects -- Problems in the Interpretation of Human Studies -- Animal Models of Cognitive Effects -- REFERENCES -- Animal Models: What Has Worked and What Is Needed -- References -- PART III CHEMICAL TIME BOMBS: ENVIRONMENTAL CAUSES OF NEURODEGENERATIVE DISEASES -- On the Identification and Measurement of Chemical Time Bombs: A Behavior Development Perspective -- METHODOLOGICAL CONSIDERATIONS -- APPROACHES TO DETECTING BEHAVIORALLY TOXIC SUBSTANCES -- A POTENTIAL TIME BOMB? -- NEW METHODS FOR MEASURING BEHAVIORAL TOXICITY -- ADDITIONAL APPROACHES AND NEW DIRECTIONS -- Multiple Behaviors Can Be Studied -- Comparative Developmental Studies Can Be Undertaken. Knowledge Concerning Neurocircuitry and Neurochemistry of the Response Is Accumulating -- ACKNOWLEDGMENT -- References -- Neurobehavioral Time Bombs: Their Nature and Their Mechanisms -- Relations Between Behavior and Chemical Environment -- CHOLINESTERASE IN PROGRESSIVE DEGENERATIVE DEMENTIAS -- Preclinical Studies of Acetylcholinesterase and Behavior -- Acetylcholinesterase in Behavioral Disorders -- THE TRUTH ABOUT A FALSE TRANSMITTER -- NEUROTROPHIC FACTORS AND BEHAVIOR -- Neurotrophic Factors -- Neurotrophic Factors and Their Environments -- Roles During Neuronal Development and Beyond -- Recovery from Morphological Lesions -- Brain Transplants -- Nerve Growth Factor, Brain Implants, and Behavior -- Behavioral Recovery from Brain Lesions -- CONTRIBUTIONS IN THE FUTURE -- NOTE -- References -- Neurobehavioral Toxicity of Selected Environmental Chemicals: Clinical and Subclinical Aspects -- CLINICAL VERSUS SUBCLINICAL NEUROTOXICITY -- NEUROBEHAVIORAL EFFECTS OF SELECTED INDUSTRIAL CHEMICALS -- Effects in the Developing Nervous System -- Lead -- Mercury -- Polychlorinated Biphenyls -- EFFECTS IN THE ADULT NERVOUS SYSTEM -- Aluminum -- Organic Solvents -- CONCLUSION -- Lack of Consistency -- Lack of Developmental Perspective -- Uncertain Health Significance -- References -- The Health Effects of Environmental Lead Exposure: Closing Pandora's Box -- HISTORY OF THE PRESENT PERSPECTIVE ON THE ENVIRONMENTAL NEUROTOXICITY OF LEAD -- OVERVIEW OF MODERN STUDIES -- Prospective Studies -- Reproductive Effects -- Early Behavioral Effects of Perinatal Lead Exposure -- Retrospective Studies on Correlation of Lead Body Burden and Behavior in Grade School Children -- Later Behavioral Concomitants of Increased Lead Burden -- Effects of Lead on Other Neuropsychological Endpoints -- Other Health Effects of Environmental Lead Exposure -- CRITICAL ISSUES. Markers of Lead Exposure -- Statistical Interpretation -- Adequacy of Behavioral Methodology -- Does Lead Contribute to Aging? -- Overview of Cost to Society -- Have Regulatory Agencies Been Slow to Act? -- CLOSING PANDORA'S BOX -- References -- Chemical Time Bombs: Environmental Causes of Neurodegenerative Diseases -- ESTABLISHING CRITERIA FOR CHEMICAL NEUROTOXICITY -- CLASSIFYING CHEMICALLY INDUCED HUMAN NEUROTOXIC DISORDERS -- THE MATURE NERVOUS SYSTEM AS CHEMICAL TARGET -- DEVELOPING NERVOUS SYSTEM AS CHEMICAL TARGET -- Scientific Basis for Neurobehavioral Toxicity Testing -- CONCLUSION -- Reference -- PART IV BEHAVIORAL ASPECTS OF NEUROTOXICITY: REGIONAL ISSUES -- Neurobehavioral Toxicity Testing in China -- INTRODUCTION -- OVERVIEW OF RESEARCH ACTIVITIES -- Carbon Disulfide -- Lead -- Simulated Video Display Terminal (VDT) Operation -- Static Magnetic Fields (SMF) -- NATIONAL AND INTERNATIONAL COOPERATION -- Mood States -- Performance Tests -- EXPECTED DIRECTIONS: BARRIERS AND RECOMMENDATIONS -- Developments in the Near Future -- Developing and Validating Test Methods -- Generating New Measuring Instruments -- Building a Computerized Evaluation System -- Limitations and Barriers -- Variation of Test Sensitivity from Study to Study -- Bias of Learning Effect -- Controlling Confounding Factors -- Interpreting Results Obtained from Neurobehavioral Tests -- Comments and Recommendations -- Training and Education -- Exploring the Possibility of Combining Quantitative Biochemical Markers and Neurobehavioral Testing -- Development, Validation, and Characterization of Methods -- SUMMARY -- Status of Research and Development of Neurobehavioral Toxicity Tests in China -- Expected Directions in the Development of Behavioral Tests of Neurotoxicity -- Problems and Recommendations -- References.
ctrlnum	(OCoLC)43477106
dewey-full	616.8
dewey-hundreds	600 - Technology (Applied sciences)
dewey-ones	616 - Diseases
dewey-raw	616.8
dewey-search	616.8
dewey-sort	3616.8
dewey-tens	610 - Medicine and health
discipline	Medizin
format	Government Document Electronic Conference Proceeding eBook
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Russell, Pamela Ebert Flattau, and Andrew M. Pope, editors.</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="a">Washington, D.C. :</subfield><subfield code="b">National Academy Press,</subfield><subfield code="c">1990.</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource (xiii, 432 pages) :</subfield><subfield code="b">illustrations</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="340" ind1=" " ind2=" "><subfield code="g">polychrome.</subfield><subfield code="2">rdacc</subfield><subfield code="0">http://rdaregistry.info/termList/RDAColourContent/1003</subfield></datafield><datafield tag="347" ind1=" " ind2=" "><subfield code="a">data file</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">"[Sponsored by] U.S. National Committee for the International Union of Psychological Science, Commission on Behavioral and Social Sciences and Education, National Research Council."</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Based on the Workshop on Behavioral Aspects of Neurotoxicity, Critical Issues, held in Aug. 1988 at the Australian National University in Canberra.</subfield></datafield><datafield tag="504" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references and index.</subfield></datafield><datafield tag="506" ind1=" " ind2=" "><subfield code="3">Use copy</subfield><subfield code="f">Restrictions unspecified</subfield><subfield code="2">star</subfield><subfield code="5">MiAaHDL</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="a">Electronic reproduction.</subfield><subfield code="b">[Place of publication not identified] :</subfield><subfield code="c">HathiTrust Digital Library,</subfield><subfield code="d">2010.</subfield><subfield code="5">MiAaHDL</subfield></datafield><datafield tag="538" ind1=" " ind2=" "><subfield code="a">Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.</subfield><subfield code="u">http://purl.oclc.org/DLF/benchrepro0212</subfield><subfield code="5">MiAaHDL</subfield></datafield><datafield tag="583" ind1="1" ind2=" "><subfield code="a">digitized</subfield><subfield code="c">2010</subfield><subfield code="h">HathiTrust Digital Library</subfield><subfield code="l">committed to preserve</subfield><subfield code="2">pda</subfield><subfield code="5">MiAaHDL</subfield></datafield><datafield tag="588" ind1="0" ind2=" "><subfield code="a">Print version record.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English.</subfield></datafield><datafield tag="505" ind1="0" ind2=" "><subfield code="a">Behavioral Measures of Neurotoxicity -- Copyright -- SYMPOSIUM CONTRIBUTORS -- PREFACE -- Contents -- INTRODUCTION -- IDENTIFICATION OF BEHAVIORAL TOXIC AGENTS -- MECHANISMS AND SITES OF ACTION -- THE MEASUREMENT OF BEHAVIOR -- THE LIFE SPAN: WHEN TO MEASURE? -- APPROACHES TO RESEARCH -- REGIONAL REQUIREMENTS -- COMMUNICATION -- CONCLUSION -- REFERENCES -- ARE NEUROTOXINS DRIVING US CRAZY? PLANETARY OBSERVATIONS ON THE CAUSES OF NEURODEGENERATIVE DISEASES OF OLD AGE -- CLINICAL FEATURES OF WESTERN PACIFIC ALS/P-D -- WHAT IS THE CAUSE OF WESTERN PACIFIC ALS/P-D? -- CYCADS: POISONOUS PLANTS USED FOR MEDICINE AND FOOD -- FROM LATHYRISM TO CYCADISM -- LINKING CYCADS TO ALS IN IRIAN JAYA AND JAPAN -- TIMING OF CYCAD EXPOSURE -- RELEVANCE FOR VETERANS OF THE PACIFIC WAR -- TOXIC COMPONENTS OF CYCADS -- SUMMARY -- REFERENCES -- PART I ASSESSMENT OF NEUROBEHAVIORAL TESTS NOW IN USE -- Methods in Behavioral Toxicology: Current Test Batteries and Need for Development -- TEST BATTERIES NOW IN USE -- Epidemiological and Field Studies -- BEHAVIORAL TOXICOLOGY IN CLINICAL PRACTICE -- BASES OF TEST SELECTION -- THE NEUROBEHAVIORAL CORE TEST BATTERY -- FUTURE DIRECTIONS: SOME CRUCIAL ISSUES -- Neuropsychological Description/Definition of Neurotoxic Syndrome(s) -- Natural History of the Neurotoxic Effects -- Dilemma Between Conservative and Progressive Approaches -- Further Questions of Test Selection -- Simple or Complex Tasks? -- Reliability of Tests and Stability of Functions -- Changes in Personality, Mood, and Affect -- Other Areas for Method Development -- SUMMARY -- References -- The Current Status of Test Development in Neurobehavioral Toxicology -- RESEARCH DESIGN AND TEST SELECTION -- REASONS FOR TEST SELECTION -- RECENT APPROACHES TO TEST BATTERY DESIGN -- Neurobehavioral Core Test Battery -- The Computerized Battery Approach.</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">Model or Theory-Based Tests and Test Batteries -- INFLUENCE ON TESTING SELECTION OF DIFFERENT OBJECTIVES FOR TESTING -- EXPECTED DIRECTIONS IN TEST DEVELOPMENT -- REMAINING BARRIERS TO TEST DEVELOPMENT -- RECOMMENDATIONS FOR FURTHER RESEARCH OR DEVELOPMENT -- References -- Human Neurobehavioral Toxicology Testing -- RATIONALES FOR DEVELOPING TEST BATTERIES -- Finland's Institute of Occupational Health Approach -- Problem-Based Approach -- Approach Recommended by the World Health Organization -- Neurobehavioral Evaluation System Approach -- TARGET ORGAN EFFECTS -- Neurotoxic Chemicals -- Exposure Populations -- Behaviors Affected by Many Chemicals -- NIOSH Recommendations -- Recommendations of the American Conference of Governmental Industrial Hygienists -- POTENTIAL OF TEST BATTERIES TO ASSESS TARGET ORGAN HEALTH EFFECTS -- DEVELOPMENT EFFORTS UNDER WAY -- NOTES -- ACKNOWLEDGMENT AND DISCLAIMER -- References -- Neurobehavioral Tests: Problems, Potential, and Prospects -- TESTS CURRENTLY IN USE -- SOME SPECIFIC POINTS -- Methods in Behavioral Toxicology (Hanninen) -- Current Status of Test Development (Williamson) -- Human Neurobehavioral Tests (Anger) -- THE ADEQUACY OF CURRENT TESTS -- SOME NEW DEVELOPMENTS IN COMPUTER-BASED ASSESSMENT -- Cognitive Componential Models -- Inferential Systems -- IMPLICATIONS FOR NEUROBEHAVIORAL ASSESSMENT -- References -- PART II ASSESSMENT OF ANIMAL MODELS: WHAT HAS WORKED AND WHAT IS NEEDED -- Exposure to Neurotoxins Throughout the Life Span: Animal Models for Linking Neurochemical Effects to Behavioral Consequences -- NEUROCHEMICAL CHANGES DURING DEVELOPMENT AND AGING -- THE CHOLINERGIC SYSTEM IN BEHAVIOR -- EFFECTS OF PRENATAL EXPOSURE TO DFP: FROM BIRTH TO WEANING -- EFFECTS OF EARLY POSTNATAL EXPOSURE TO DFP -- EFFECTS OF EXPOSURE TO DFP: SENESCENT RATS -- Genetic (Strain-Specific) Differences in Effects.</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">Subchronic Intoxication During Senescence -- Time-Course Recovery of mAChRs Following Down-Regulation in Brain of Senescent Rats -- CONCLUSION -- References -- Animal Models of Dementia: Their Relevance to Neurobehavioral Toxicology Testing -- ANIMAL MODELS OF DEMENTIA -- ENVIRONMENTAL CHALLENGES -- PHARMACOLOGICAL CHALLENGES -- MEASURING BEHAVIORAL EFFECTS: SPECIFIC PARADIGMS -- Inhibitory (Passive) Avoidance -- Active Avoidance Tasks -- Operant Conditioning -- Maze Learning -- Other Measures -- CONCLUSION -- ACKNOWLEDGMENTS -- References -- Bridging Experimental Animal and Human Behavioral Toxicology Studies -- THE SCOPE AND AGENDA OF BEHAVIORAL TOXICOLOGY -- STATE OF DEVELOPMENT -- BARRIERS TO ADVANCEMENT -- ACCELERATING THE PACE -- References -- Methods and Issues in Evaluating the Neurotoxic Effects of Organic Solvents -- ACUTE SOLVENT EFFECTS -- APPLICATION OF ANIMAL BEHAVIORAL METHODS -- Acute Effects of Single Exposures -- Acute Effects in the Context of Chronic Exposures -- Reinforcing Properties of Organic Solvents -- CHRONIC SOLVENT EFFECTS ON THE PERIPHERAL NERVOUS SYSTEM -- The Role of Animal Studies -- Neurobehavioral Methods for Screening Sensory and Motor Effects -- Problems in the Interpretation of Human Studies -- Animal Models of Cognitive Effects -- REFERENCES -- Animal Models: What Has Worked and What Is Needed -- References -- PART III CHEMICAL TIME BOMBS: ENVIRONMENTAL CAUSES OF NEURODEGENERATIVE DISEASES -- On the Identification and Measurement of Chemical Time Bombs: A Behavior Development Perspective -- METHODOLOGICAL CONSIDERATIONS -- APPROACHES TO DETECTING BEHAVIORALLY TOXIC SUBSTANCES -- A POTENTIAL TIME BOMB? -- NEW METHODS FOR MEASURING BEHAVIORAL TOXICITY -- ADDITIONAL APPROACHES AND NEW DIRECTIONS -- Multiple Behaviors Can Be Studied -- Comparative Developmental Studies Can Be Undertaken.</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">Knowledge Concerning Neurocircuitry and Neurochemistry of the Response Is Accumulating -- ACKNOWLEDGMENT -- References -- Neurobehavioral Time Bombs: Their Nature and Their Mechanisms -- Relations Between Behavior and Chemical Environment -- CHOLINESTERASE IN PROGRESSIVE DEGENERATIVE DEMENTIAS -- Preclinical Studies of Acetylcholinesterase and Behavior -- Acetylcholinesterase in Behavioral Disorders -- THE TRUTH ABOUT A FALSE TRANSMITTER -- NEUROTROPHIC FACTORS AND BEHAVIOR -- Neurotrophic Factors -- Neurotrophic Factors and Their 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Behavioral Effects of Perinatal Lead Exposure -- Retrospective Studies on Correlation of Lead Body Burden and Behavior in Grade School Children -- Later Behavioral Concomitants of Increased Lead Burden -- Effects of Lead on Other Neuropsychological Endpoints -- Other Health Effects of Environmental Lead Exposure -- CRITICAL ISSUES.</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">Markers of Lead Exposure -- Statistical Interpretation -- Adequacy of Behavioral Methodology -- Does Lead Contribute to Aging? -- Overview of Cost to Society -- Have Regulatory Agencies Been Slow to Act? -- CLOSING PANDORA'S BOX -- References -- Chemical Time Bombs: Environmental Causes of Neurodegenerative Diseases -- ESTABLISHING CRITERIA FOR CHEMICAL NEUROTOXICITY -- CLASSIFYING CHEMICALLY INDUCED HUMAN NEUROTOXIC DISORDERS -- THE MATURE NERVOUS SYSTEM AS CHEMICAL TARGET -- DEVELOPING NERVOUS SYSTEM AS CHEMICAL TARGET -- Scientific Basis for Neurobehavioral Toxicity Testing -- 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spelling	Behavioral measures of neurotoxicity : report of a symposium / Roger W. Russell, Pamela Ebert Flattau, and Andrew M. Pope, editors. Washington, D.C. : National Academy Press, 1990. 1 online resource (xiii, 432 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier polychrome. rdacc http://rdaregistry.info/termList/RDAColourContent/1003 data file "[Sponsored by] U.S. National Committee for the International Union of Psychological Science, Commission on Behavioral and Social Sciences and Education, National Research Council." Based on the Workshop on Behavioral Aspects of Neurotoxicity, Critical Issues, held in Aug. 1988 at the Australian National University in Canberra. Includes bibliographical references and index. Use copy Restrictions unspecified star MiAaHDL Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010. MiAaHDL Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL Print version record. English. Behavioral Measures of Neurotoxicity -- Copyright -- SYMPOSIUM CONTRIBUTORS -- PREFACE -- Contents -- INTRODUCTION -- IDENTIFICATION OF BEHAVIORAL TOXIC AGENTS -- MECHANISMS AND SITES OF ACTION -- THE MEASUREMENT OF BEHAVIOR -- THE LIFE SPAN: WHEN TO MEASURE? -- APPROACHES TO RESEARCH -- REGIONAL REQUIREMENTS -- COMMUNICATION -- CONCLUSION -- REFERENCES -- ARE NEUROTOXINS DRIVING US CRAZY? PLANETARY OBSERVATIONS ON THE CAUSES OF NEURODEGENERATIVE DISEASES OF OLD AGE -- CLINICAL FEATURES OF WESTERN PACIFIC ALS/P-D -- WHAT IS THE CAUSE OF WESTERN PACIFIC ALS/P-D? -- CYCADS: POISONOUS PLANTS USED FOR MEDICINE AND FOOD -- FROM LATHYRISM TO CYCADISM -- LINKING CYCADS TO ALS IN IRIAN JAYA AND JAPAN -- TIMING OF CYCAD EXPOSURE -- RELEVANCE FOR VETERANS OF THE PACIFIC WAR -- TOXIC COMPONENTS OF CYCADS -- SUMMARY -- REFERENCES -- PART I ASSESSMENT OF NEUROBEHAVIORAL TESTS NOW IN USE -- Methods in Behavioral Toxicology: Current Test Batteries and Need for Development -- TEST BATTERIES NOW IN USE -- Epidemiological and Field Studies -- BEHAVIORAL TOXICOLOGY IN CLINICAL PRACTICE -- BASES OF TEST SELECTION -- THE NEUROBEHAVIORAL CORE TEST BATTERY -- FUTURE DIRECTIONS: SOME CRUCIAL ISSUES -- Neuropsychological Description/Definition of Neurotoxic Syndrome(s) -- Natural History of the Neurotoxic Effects -- Dilemma Between Conservative and Progressive Approaches -- Further Questions of Test Selection -- Simple or Complex Tasks? -- Reliability of Tests and Stability of Functions -- Changes in Personality, Mood, and Affect -- Other Areas for Method Development -- SUMMARY -- References -- The Current Status of Test Development in Neurobehavioral Toxicology -- RESEARCH DESIGN AND TEST SELECTION -- REASONS FOR TEST SELECTION -- RECENT APPROACHES TO TEST BATTERY DESIGN -- Neurobehavioral Core Test Battery -- The Computerized Battery Approach. Model or Theory-Based Tests and Test Batteries -- INFLUENCE ON TESTING SELECTION OF DIFFERENT OBJECTIVES FOR TESTING -- EXPECTED DIRECTIONS IN TEST DEVELOPMENT -- REMAINING BARRIERS TO TEST DEVELOPMENT -- RECOMMENDATIONS FOR FURTHER RESEARCH OR DEVELOPMENT -- References -- Human Neurobehavioral Toxicology Testing -- RATIONALES FOR DEVELOPING TEST BATTERIES -- Finland's Institute of Occupational Health Approach -- Problem-Based Approach -- Approach Recommended by the World Health Organization -- Neurobehavioral Evaluation System Approach -- TARGET ORGAN EFFECTS -- Neurotoxic Chemicals -- Exposure Populations -- Behaviors Affected by Many Chemicals -- NIOSH Recommendations -- Recommendations of the American Conference of Governmental Industrial Hygienists -- POTENTIAL OF TEST BATTERIES TO ASSESS TARGET ORGAN HEALTH EFFECTS -- DEVELOPMENT EFFORTS UNDER WAY -- NOTES -- ACKNOWLEDGMENT AND DISCLAIMER -- References -- Neurobehavioral Tests: Problems, Potential, and Prospects -- TESTS CURRENTLY IN USE -- SOME SPECIFIC POINTS -- Methods in Behavioral Toxicology (Hanninen) -- Current Status of Test Development (Williamson) -- Human Neurobehavioral Tests (Anger) -- THE ADEQUACY OF CURRENT TESTS -- SOME NEW DEVELOPMENTS IN COMPUTER-BASED ASSESSMENT -- Cognitive Componential Models -- Inferential Systems -- IMPLICATIONS FOR NEUROBEHAVIORAL ASSESSMENT -- References -- PART II ASSESSMENT OF ANIMAL MODELS: WHAT HAS WORKED AND WHAT IS NEEDED -- Exposure to Neurotoxins Throughout the Life Span: Animal Models for Linking Neurochemical Effects to Behavioral Consequences -- NEUROCHEMICAL CHANGES DURING DEVELOPMENT AND AGING -- THE CHOLINERGIC SYSTEM IN BEHAVIOR -- EFFECTS OF PRENATAL EXPOSURE TO DFP: FROM BIRTH TO WEANING -- EFFECTS OF EARLY POSTNATAL EXPOSURE TO DFP -- EFFECTS OF EXPOSURE TO DFP: SENESCENT RATS -- Genetic (Strain-Specific) Differences in Effects. Subchronic Intoxication During Senescence -- Time-Course Recovery of mAChRs Following Down-Regulation in Brain of Senescent Rats -- CONCLUSION -- References -- Animal Models of Dementia: Their Relevance to Neurobehavioral Toxicology Testing -- ANIMAL MODELS OF DEMENTIA -- ENVIRONMENTAL CHALLENGES -- PHARMACOLOGICAL CHALLENGES -- MEASURING BEHAVIORAL EFFECTS: SPECIFIC PARADIGMS -- Inhibitory (Passive) Avoidance -- Active Avoidance Tasks -- Operant Conditioning -- Maze Learning -- Other Measures -- CONCLUSION -- ACKNOWLEDGMENTS -- References -- Bridging Experimental Animal and Human Behavioral Toxicology Studies -- THE SCOPE AND AGENDA OF BEHAVIORAL TOXICOLOGY -- STATE OF DEVELOPMENT -- BARRIERS TO ADVANCEMENT -- ACCELERATING THE PACE -- References -- Methods and Issues in Evaluating the Neurotoxic Effects of Organic Solvents -- ACUTE SOLVENT EFFECTS -- APPLICATION OF ANIMAL BEHAVIORAL METHODS -- Acute Effects of Single Exposures -- Acute Effects in the Context of Chronic Exposures -- Reinforcing Properties of Organic Solvents -- CHRONIC SOLVENT EFFECTS ON THE PERIPHERAL NERVOUS SYSTEM -- The Role of Animal Studies -- Neurobehavioral Methods for Screening Sensory and Motor Effects -- Problems in the Interpretation of Human Studies -- Animal Models of Cognitive Effects -- REFERENCES -- Animal Models: What Has Worked and What Is Needed -- References -- PART III CHEMICAL TIME BOMBS: ENVIRONMENTAL CAUSES OF NEURODEGENERATIVE DISEASES -- On the Identification and Measurement of Chemical Time Bombs: A Behavior Development Perspective -- METHODOLOGICAL CONSIDERATIONS -- APPROACHES TO DETECTING BEHAVIORALLY TOXIC SUBSTANCES -- A POTENTIAL TIME BOMB? -- NEW METHODS FOR MEASURING BEHAVIORAL TOXICITY -- ADDITIONAL APPROACHES AND NEW DIRECTIONS -- Multiple Behaviors Can Be Studied -- Comparative Developmental Studies Can Be Undertaken. Knowledge Concerning Neurocircuitry and Neurochemistry of the Response Is Accumulating -- ACKNOWLEDGMENT -- References -- Neurobehavioral Time Bombs: Their Nature and Their Mechanisms -- Relations Between Behavior and Chemical Environment -- CHOLINESTERASE IN PROGRESSIVE DEGENERATIVE DEMENTIAS -- Preclinical Studies of Acetylcholinesterase and Behavior -- Acetylcholinesterase in Behavioral Disorders -- THE TRUTH ABOUT A FALSE TRANSMITTER -- NEUROTROPHIC FACTORS AND BEHAVIOR -- Neurotrophic Factors -- Neurotrophic Factors and Their Environments -- Roles During Neuronal Development and Beyond -- Recovery from Morphological Lesions -- Brain Transplants -- Nerve Growth Factor, Brain Implants, and Behavior -- Behavioral Recovery from Brain Lesions -- CONTRIBUTIONS IN THE FUTURE -- NOTE -- References -- Neurobehavioral Toxicity of Selected Environmental Chemicals: Clinical and Subclinical Aspects -- CLINICAL VERSUS SUBCLINICAL NEUROTOXICITY -- NEUROBEHAVIORAL EFFECTS OF SELECTED INDUSTRIAL CHEMICALS -- Effects in the Developing Nervous System -- Lead -- Mercury -- Polychlorinated Biphenyls -- EFFECTS IN THE ADULT NERVOUS SYSTEM -- Aluminum -- Organic Solvents -- CONCLUSION -- Lack of Consistency -- Lack of Developmental Perspective -- Uncertain Health Significance -- References -- The Health Effects of Environmental Lead Exposure: Closing Pandora's Box -- HISTORY OF THE PRESENT PERSPECTIVE ON THE ENVIRONMENTAL NEUROTOXICITY OF LEAD -- OVERVIEW OF MODERN STUDIES -- Prospective Studies -- Reproductive Effects -- Early Behavioral Effects of Perinatal Lead Exposure -- Retrospective Studies on Correlation of Lead Body Burden and Behavior in Grade School Children -- Later Behavioral Concomitants of Increased Lead Burden -- Effects of Lead on Other Neuropsychological Endpoints -- Other Health Effects of Environmental Lead Exposure -- CRITICAL ISSUES. Markers of Lead Exposure -- Statistical Interpretation -- Adequacy of Behavioral Methodology -- Does Lead Contribute to Aging? -- Overview of Cost to Society -- Have Regulatory Agencies Been Slow to Act? -- CLOSING PANDORA'S BOX -- References -- Chemical Time Bombs: Environmental Causes of Neurodegenerative Diseases -- ESTABLISHING CRITERIA FOR CHEMICAL NEUROTOXICITY -- CLASSIFYING CHEMICALLY INDUCED HUMAN NEUROTOXIC DISORDERS -- THE MATURE NERVOUS SYSTEM AS CHEMICAL TARGET -- DEVELOPING NERVOUS SYSTEM AS CHEMICAL TARGET -- Scientific Basis for Neurobehavioral Toxicity Testing -- CONCLUSION -- Reference -- PART IV BEHAVIORAL ASPECTS OF NEUROTOXICITY: REGIONAL ISSUES -- Neurobehavioral Toxicity Testing in China -- INTRODUCTION -- OVERVIEW OF RESEARCH ACTIVITIES -- Carbon Disulfide -- Lead -- Simulated Video Display Terminal (VDT) Operation -- Static Magnetic Fields (SMF) -- NATIONAL AND INTERNATIONAL COOPERATION -- Mood States -- Performance Tests -- EXPECTED DIRECTIONS: BARRIERS AND RECOMMENDATIONS -- Developments in the Near Future -- Developing and Validating Test Methods -- Generating New Measuring Instruments -- Building a Computerized Evaluation System -- Limitations and Barriers -- Variation of Test Sensitivity from Study to Study -- Bias of Learning Effect -- Controlling Confounding Factors -- Interpreting Results Obtained from Neurobehavioral Tests -- Comments and Recommendations -- Training and Education -- Exploring the Possibility of Combining Quantitative Biochemical Markers and Neurobehavioral Testing -- Development, Validation, and Characterization of Methods -- SUMMARY -- Status of Research and Development of Neurobehavioral Toxicity Tests in China -- Expected Directions in the Development of Behavioral Tests of Neurotoxicity -- Problems and Recommendations -- References. Neurotoxicology Congresses. Behavioral toxicology Congresses. Nervous system Diseases Environmental aspects Congresses. Neuropsychological tests Congresses. Diseases. http://id.loc.gov/authorities/subjects/sh85038411 Nervous system Diseases. http://id.loc.gov/authorities/subjects/sh85090924 Neurotoxic agents. http://id.loc.gov/authorities/subjects/sh85091181 Human behavior. http://id.loc.gov/authorities/subjects/sh85062839 Environmental toxicology Congresses. Disease Behavior and Behavior Mechanisms Noxae Publication Formats Psychiatry and Psychology Publication Characteristics Toxic Actions Chemical Actions and Uses Chemicals and Drugs Nervous System Diseases Neurotoxins Behavior Congresses Neurotoxicologie Congrès. Écotoxicologie Congrès. Système nerveux Maladies Aspect de l'environnement Congrès. Tests neuropsychologiques Congrès. Toxicologie du comportement Congrès. Maladies. Système nerveux Maladies. Neurotoxines. Comportement humain. human behavior. aat HEALTH & FITNESS Diseases Nervous System (incl. Brain) bisacsh MEDICAL Neurology. bisacsh Neurotoxic agents fast Nervous system Diseases fast Human behavior fast Environmental toxicology fast Diseases fast Behavioral toxicology fast Neuropsychological tests fast Neurotoxicology fast Umweltchemikalie gnd http://d-nb.info/gnd/4117281-4 Neurotoxizität gnd http://d-nb.info/gnd/4123836-9 Verhaltenstest gnd http://d-nb.info/gnd/4245686-1 Kongress gnd Nervengift gnd http://d-nb.info/gnd/4171484-2 Toxizitätstest gnd http://d-nb.info/gnd/4060540-1 Congress proceedings (reports) aat Conference papers and proceedings fast Conference papers and proceedings. lcgft http://id.loc.gov/authorities/genreForms/gf2014026068 Actes de congrès. rvmgf Russell, Roger W. Flattau, Pamela Ebert. Pope, Andrew MacPherson, 1950- https://id.oclc.org/worldcat/entity/E39PCjFyR4RCKGhy6Bf8DXWRXb http://id.loc.gov/authorities/names/n87820748 U.S. National Committee for the International Union of Psychological Science. http://id.loc.gov/authorities/names/n88290637 National Research Council (U.S.). Commission on Behavioral and Social Sciences and Education. http://id.loc.gov/authorities/names/n82095643 National Research Council (U.S.) http://id.loc.gov/authorities/names/n79036113 Workshop on Behavioral Aspects of Neurotoxicity: Critical Issues (1988 : Australian National University) http://id.loc.gov/authorities/names/n88290636 Print version: Behavioral measures of neurotoxicity. Washington, D.C. : National Academy Press, 1990 0309040477 (DLC) 90006565 (OCoLC)22005935 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=14461 Volltext
spellingShingle	Behavioral measures of neurotoxicity : report of a symposium / Behavioral Measures of Neurotoxicity -- Copyright -- SYMPOSIUM CONTRIBUTORS -- PREFACE -- Contents -- INTRODUCTION -- IDENTIFICATION OF BEHAVIORAL TOXIC AGENTS -- MECHANISMS AND SITES OF ACTION -- THE MEASUREMENT OF BEHAVIOR -- THE LIFE SPAN: WHEN TO MEASURE? -- APPROACHES TO RESEARCH -- REGIONAL REQUIREMENTS -- COMMUNICATION -- CONCLUSION -- REFERENCES -- ARE NEUROTOXINS DRIVING US CRAZY? PLANETARY OBSERVATIONS ON THE CAUSES OF NEURODEGENERATIVE DISEASES OF OLD AGE -- CLINICAL FEATURES OF WESTERN PACIFIC ALS/P-D -- WHAT IS THE CAUSE OF WESTERN PACIFIC ALS/P-D? -- CYCADS: POISONOUS PLANTS USED FOR MEDICINE AND FOOD -- FROM LATHYRISM TO CYCADISM -- LINKING CYCADS TO ALS IN IRIAN JAYA AND JAPAN -- TIMING OF CYCAD EXPOSURE -- RELEVANCE FOR VETERANS OF THE PACIFIC WAR -- TOXIC COMPONENTS OF CYCADS -- SUMMARY -- REFERENCES -- PART I ASSESSMENT OF NEUROBEHAVIORAL TESTS NOW IN USE -- Methods in Behavioral Toxicology: Current Test Batteries and Need for Development -- TEST BATTERIES NOW IN USE -- Epidemiological and Field Studies -- BEHAVIORAL TOXICOLOGY IN CLINICAL PRACTICE -- BASES OF TEST SELECTION -- THE NEUROBEHAVIORAL CORE TEST BATTERY -- FUTURE DIRECTIONS: SOME CRUCIAL ISSUES -- Neuropsychological Description/Definition of Neurotoxic Syndrome(s) -- Natural History of the Neurotoxic Effects -- Dilemma Between Conservative and Progressive Approaches -- Further Questions of Test Selection -- Simple or Complex Tasks? -- Reliability of Tests and Stability of Functions -- Changes in Personality, Mood, and Affect -- Other Areas for Method Development -- SUMMARY -- References -- The Current Status of Test Development in Neurobehavioral Toxicology -- RESEARCH DESIGN AND TEST SELECTION -- REASONS FOR TEST SELECTION -- RECENT APPROACHES TO TEST BATTERY DESIGN -- Neurobehavioral Core Test Battery -- The Computerized Battery Approach. Model or Theory-Based Tests and Test Batteries -- INFLUENCE ON TESTING SELECTION OF DIFFERENT OBJECTIVES FOR TESTING -- EXPECTED DIRECTIONS IN TEST DEVELOPMENT -- REMAINING BARRIERS TO TEST DEVELOPMENT -- RECOMMENDATIONS FOR FURTHER RESEARCH OR DEVELOPMENT -- References -- Human Neurobehavioral Toxicology Testing -- RATIONALES FOR DEVELOPING TEST BATTERIES -- Finland's Institute of Occupational Health Approach -- Problem-Based Approach -- Approach Recommended by the World Health Organization -- Neurobehavioral Evaluation System Approach -- TARGET ORGAN EFFECTS -- Neurotoxic Chemicals -- Exposure Populations -- Behaviors Affected by Many Chemicals -- NIOSH Recommendations -- Recommendations of the American Conference of Governmental Industrial Hygienists -- POTENTIAL OF TEST BATTERIES TO ASSESS TARGET ORGAN HEALTH EFFECTS -- DEVELOPMENT EFFORTS UNDER WAY -- NOTES -- ACKNOWLEDGMENT AND DISCLAIMER -- References -- Neurobehavioral Tests: Problems, Potential, and Prospects -- TESTS CURRENTLY IN USE -- SOME SPECIFIC POINTS -- Methods in Behavioral Toxicology (Hanninen) -- Current Status of Test Development (Williamson) -- Human Neurobehavioral Tests (Anger) -- THE ADEQUACY OF CURRENT TESTS -- SOME NEW DEVELOPMENTS IN COMPUTER-BASED ASSESSMENT -- Cognitive Componential Models -- Inferential Systems -- IMPLICATIONS FOR NEUROBEHAVIORAL ASSESSMENT -- References -- PART II ASSESSMENT OF ANIMAL MODELS: WHAT HAS WORKED AND WHAT IS NEEDED -- Exposure to Neurotoxins Throughout the Life Span: Animal Models for Linking Neurochemical Effects to Behavioral Consequences -- NEUROCHEMICAL CHANGES DURING DEVELOPMENT AND AGING -- THE CHOLINERGIC SYSTEM IN BEHAVIOR -- EFFECTS OF PRENATAL EXPOSURE TO DFP: FROM BIRTH TO WEANING -- EFFECTS OF EARLY POSTNATAL EXPOSURE TO DFP -- EFFECTS OF EXPOSURE TO DFP: SENESCENT RATS -- Genetic (Strain-Specific) Differences in Effects. Subchronic Intoxication During Senescence -- Time-Course Recovery of mAChRs Following Down-Regulation in Brain of Senescent Rats -- CONCLUSION -- References -- Animal Models of Dementia: Their Relevance to Neurobehavioral Toxicology Testing -- ANIMAL MODELS OF DEMENTIA -- ENVIRONMENTAL CHALLENGES -- PHARMACOLOGICAL CHALLENGES -- MEASURING BEHAVIORAL EFFECTS: SPECIFIC PARADIGMS -- Inhibitory (Passive) Avoidance -- Active Avoidance Tasks -- Operant Conditioning -- Maze Learning -- Other Measures -- CONCLUSION -- ACKNOWLEDGMENTS -- References -- Bridging Experimental Animal and Human Behavioral Toxicology Studies -- THE SCOPE AND AGENDA OF BEHAVIORAL TOXICOLOGY -- STATE OF DEVELOPMENT -- BARRIERS TO ADVANCEMENT -- ACCELERATING THE PACE -- References -- Methods and Issues in Evaluating the Neurotoxic Effects of Organic Solvents -- ACUTE SOLVENT EFFECTS -- APPLICATION OF ANIMAL BEHAVIORAL METHODS -- Acute Effects of Single Exposures -- Acute Effects in the Context of Chronic Exposures -- Reinforcing Properties of Organic Solvents -- CHRONIC SOLVENT EFFECTS ON THE PERIPHERAL NERVOUS SYSTEM -- The Role of Animal Studies -- Neurobehavioral Methods for Screening Sensory and Motor Effects -- Problems in the Interpretation of Human Studies -- Animal Models of Cognitive Effects -- REFERENCES -- Animal Models: What Has Worked and What Is Needed -- References -- PART III CHEMICAL TIME BOMBS: ENVIRONMENTAL CAUSES OF NEURODEGENERATIVE DISEASES -- On the Identification and Measurement of Chemical Time Bombs: A Behavior Development Perspective -- METHODOLOGICAL CONSIDERATIONS -- APPROACHES TO DETECTING BEHAVIORALLY TOXIC SUBSTANCES -- A POTENTIAL TIME BOMB? -- NEW METHODS FOR MEASURING BEHAVIORAL TOXICITY -- ADDITIONAL APPROACHES AND NEW DIRECTIONS -- Multiple Behaviors Can Be Studied -- Comparative Developmental Studies Can Be Undertaken. Knowledge Concerning Neurocircuitry and Neurochemistry of the Response Is Accumulating -- ACKNOWLEDGMENT -- References -- Neurobehavioral Time Bombs: Their Nature and Their Mechanisms -- Relations Between Behavior and Chemical Environment -- CHOLINESTERASE IN PROGRESSIVE DEGENERATIVE DEMENTIAS -- Preclinical Studies of Acetylcholinesterase and Behavior -- Acetylcholinesterase in Behavioral Disorders -- THE TRUTH ABOUT A FALSE TRANSMITTER -- NEUROTROPHIC FACTORS AND BEHAVIOR -- Neurotrophic Factors -- Neurotrophic Factors and Their Environments -- Roles During Neuronal Development and Beyond -- Recovery from Morphological Lesions -- Brain Transplants -- Nerve Growth Factor, Brain Implants, and Behavior -- Behavioral Recovery from Brain Lesions -- CONTRIBUTIONS IN THE FUTURE -- NOTE -- References -- Neurobehavioral Toxicity of Selected Environmental Chemicals: Clinical and Subclinical Aspects -- CLINICAL VERSUS SUBCLINICAL NEUROTOXICITY -- NEUROBEHAVIORAL EFFECTS OF SELECTED INDUSTRIAL CHEMICALS -- Effects in the Developing Nervous System -- Lead -- Mercury -- Polychlorinated Biphenyls -- EFFECTS IN THE ADULT NERVOUS SYSTEM -- Aluminum -- Organic Solvents -- CONCLUSION -- Lack of Consistency -- Lack of Developmental Perspective -- Uncertain Health Significance -- References -- The Health Effects of Environmental Lead Exposure: Closing Pandora's Box -- HISTORY OF THE PRESENT PERSPECTIVE ON THE ENVIRONMENTAL NEUROTOXICITY OF LEAD -- OVERVIEW OF MODERN STUDIES -- Prospective Studies -- Reproductive Effects -- Early Behavioral Effects of Perinatal Lead Exposure -- Retrospective Studies on Correlation of Lead Body Burden and Behavior in Grade School Children -- Later Behavioral Concomitants of Increased Lead Burden -- Effects of Lead on Other Neuropsychological Endpoints -- Other Health Effects of Environmental Lead Exposure -- CRITICAL ISSUES. Markers of Lead Exposure -- Statistical Interpretation -- Adequacy of Behavioral Methodology -- Does Lead Contribute to Aging? -- Overview of Cost to Society -- Have Regulatory Agencies Been Slow to Act? -- CLOSING PANDORA'S BOX -- References -- Chemical Time Bombs: Environmental Causes of Neurodegenerative Diseases -- ESTABLISHING CRITERIA FOR CHEMICAL NEUROTOXICITY -- CLASSIFYING CHEMICALLY INDUCED HUMAN NEUROTOXIC DISORDERS -- THE MATURE NERVOUS SYSTEM AS CHEMICAL TARGET -- DEVELOPING NERVOUS SYSTEM AS CHEMICAL TARGET -- Scientific Basis for Neurobehavioral Toxicity Testing -- CONCLUSION -- Reference -- PART IV BEHAVIORAL ASPECTS OF NEUROTOXICITY: REGIONAL ISSUES -- Neurobehavioral Toxicity Testing in China -- INTRODUCTION -- OVERVIEW OF RESEARCH ACTIVITIES -- Carbon Disulfide -- Lead -- Simulated Video Display Terminal (VDT) Operation -- Static Magnetic Fields (SMF) -- NATIONAL AND INTERNATIONAL COOPERATION -- Mood States -- Performance Tests -- EXPECTED DIRECTIONS: BARRIERS AND RECOMMENDATIONS -- Developments in the Near Future -- Developing and Validating Test Methods -- Generating New Measuring Instruments -- Building a Computerized Evaluation System -- Limitations and Barriers -- Variation of Test Sensitivity from Study to Study -- Bias of Learning Effect -- Controlling Confounding Factors -- Interpreting Results Obtained from Neurobehavioral Tests -- Comments and Recommendations -- Training and Education -- Exploring the Possibility of Combining Quantitative Biochemical Markers and Neurobehavioral Testing -- Development, Validation, and Characterization of Methods -- SUMMARY -- Status of Research and Development of Neurobehavioral Toxicity Tests in China -- Expected Directions in the Development of Behavioral Tests of Neurotoxicity -- Problems and Recommendations -- References. Neurotoxicology Congresses. Behavioral toxicology Congresses. Nervous system Diseases Environmental aspects Congresses. Neuropsychological tests Congresses. Diseases. http://id.loc.gov/authorities/subjects/sh85038411 Nervous system Diseases. http://id.loc.gov/authorities/subjects/sh85090924 Neurotoxic agents. http://id.loc.gov/authorities/subjects/sh85091181 Human behavior. http://id.loc.gov/authorities/subjects/sh85062839 Environmental toxicology Congresses. Disease Behavior and Behavior Mechanisms Noxae Publication Formats Psychiatry and Psychology Publication Characteristics Toxic Actions Chemical Actions and Uses Chemicals and Drugs Nervous System Diseases Neurotoxins Behavior Congresses Neurotoxicologie Congrès. Écotoxicologie Congrès. Système nerveux Maladies Aspect de l'environnement Congrès. Tests neuropsychologiques Congrès. Toxicologie du comportement Congrès. Maladies. Système nerveux Maladies. Neurotoxines. Comportement humain. human behavior. aat HEALTH & FITNESS Diseases Nervous System (incl. Brain) bisacsh MEDICAL Neurology. bisacsh Neurotoxic agents fast Nervous system Diseases fast Human behavior fast Environmental toxicology fast Diseases fast Behavioral toxicology fast Neuropsychological tests fast Neurotoxicology fast Umweltchemikalie gnd http://d-nb.info/gnd/4117281-4 Neurotoxizität gnd http://d-nb.info/gnd/4123836-9 Verhaltenstest gnd http://d-nb.info/gnd/4245686-1 Kongress gnd Nervengift gnd http://d-nb.info/gnd/4171484-2 Toxizitätstest gnd http://d-nb.info/gnd/4060540-1
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title	Behavioral measures of neurotoxicity : report of a symposium /
title_auth	Behavioral measures of neurotoxicity : report of a symposium /
title_exact_search	Behavioral measures of neurotoxicity : report of a symposium /
title_full	Behavioral measures of neurotoxicity : report of a symposium / Roger W. Russell, Pamela Ebert Flattau, and Andrew M. Pope, editors.
title_fullStr	Behavioral measures of neurotoxicity : report of a symposium / Roger W. Russell, Pamela Ebert Flattau, and Andrew M. Pope, editors.
title_full_unstemmed	Behavioral measures of neurotoxicity : report of a symposium / Roger W. Russell, Pamela Ebert Flattau, and Andrew M. Pope, editors.
title_short	Behavioral measures of neurotoxicity :
title_sort	behavioral measures of neurotoxicity report of a symposium
title_sub	report of a symposium /
topic	Neurotoxicology Congresses. Behavioral toxicology Congresses. Nervous system Diseases Environmental aspects Congresses. Neuropsychological tests Congresses. Diseases. http://id.loc.gov/authorities/subjects/sh85038411 Nervous system Diseases. http://id.loc.gov/authorities/subjects/sh85090924 Neurotoxic agents. http://id.loc.gov/authorities/subjects/sh85091181 Human behavior. http://id.loc.gov/authorities/subjects/sh85062839 Environmental toxicology Congresses. Disease Behavior and Behavior Mechanisms Noxae Publication Formats Psychiatry and Psychology Publication Characteristics Toxic Actions Chemical Actions and Uses Chemicals and Drugs Nervous System Diseases Neurotoxins Behavior Congresses Neurotoxicologie Congrès. Écotoxicologie Congrès. Système nerveux Maladies Aspect de l'environnement Congrès. Tests neuropsychologiques Congrès. Toxicologie du comportement Congrès. Maladies. Système nerveux Maladies. Neurotoxines. Comportement humain. human behavior. aat HEALTH & FITNESS Diseases Nervous System (incl. Brain) bisacsh MEDICAL Neurology. bisacsh Neurotoxic agents fast Nervous system Diseases fast Human behavior fast Environmental toxicology fast Diseases fast Behavioral toxicology fast Neuropsychological tests fast Neurotoxicology fast Umweltchemikalie gnd http://d-nb.info/gnd/4117281-4 Neurotoxizität gnd http://d-nb.info/gnd/4123836-9 Verhaltenstest gnd http://d-nb.info/gnd/4245686-1 Kongress gnd Nervengift gnd http://d-nb.info/gnd/4171484-2 Toxizitätstest gnd http://d-nb.info/gnd/4060540-1
topic_facet	Neurotoxicology Congresses. Behavioral toxicology Congresses. Nervous system Diseases Environmental aspects Congresses. Neuropsychological tests Congresses. Diseases. Nervous system Diseases. Neurotoxic agents. Human behavior. Environmental toxicology Congresses. Disease Behavior and Behavior Mechanisms Noxae Publication Formats Psychiatry and Psychology Publication Characteristics Toxic Actions Chemical Actions and Uses Chemicals and Drugs Nervous System Diseases Neurotoxins Behavior Congresses Neurotoxicologie Congrès. Écotoxicologie Congrès. Système nerveux Maladies Aspect de l'environnement Congrès. Tests neuropsychologiques Congrès. Toxicologie du comportement Congrès. Maladies. Système nerveux Maladies. Neurotoxines. Comportement humain. human behavior. HEALTH & FITNESS Diseases Nervous System (incl. Brain) MEDICAL Neurology. Neurotoxic agents Nervous system Diseases Human behavior Environmental toxicology Diseases Behavioral toxicology Neuropsychological tests Neurotoxicology Umweltchemikalie Neurotoxizität Verhaltenstest Kongress Nervengift Toxizitätstest Congress proceedings (reports) Conference papers and proceedings Conference papers and proceedings. Actes de congrès.
url	https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=14461
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