Unreliable: bias, fraud, and the reproducibility crisis in biomedical research
"Scientists specializing in the in-depth analysis of the published scientific literature have to the conclusion that a large part of the scientific literature covers results that cannot be replicated in other independent laboratories. Scientists take this to mean that the results are unreliable...
Saved in:
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
New York
Columbia University Press
[2025]
|
| Subjects: | |
| Summary: | "Scientists specializing in the in-depth analysis of the published scientific literature have to the conclusion that a large part of the scientific literature covers results that cannot be replicated in other independent laboratories. Scientists take this to mean that the results are unreliable or untrue. In this book, biomedical researcher Csaba Szabo summarizes the causes and consequences of this so-called "reproducibility crisis" in biomedical research. The range of causes is wide, from the specificities of the methods used, through various pitfalls in the design of experiments and analysis of experimental data (e.g., confirmation bias), plagiarism and deliberate data falsification, to the systematic publication of fictitious experiments that have never been performed. Through a few blatant examples - e.g. Anil Potti (Duke University); Piero Anversa (Harvard University) - Szabo describes the damaging impact that blatant fraud can have on the development of an entire field of science, and introduces some of the maverick "science investigators" - often working in anonymity - who devote their lives to tracking down and exposing scientific fraudsters. The book also answers the questions (a) what individual and systemic factors are involved in allowing these phenomena to occur, (b) why the appropriate steps have not been taken to control them, and (c) what the implications of the crisis are for the future of medicine and, within it, for the development of new drugs"-- |
| Physical Description: | XI, 314 Seiten Illustrationen, Diagramme 24 cm |
| ISBN: | 9780231216234 |
Staff View
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV050229031 | ||
| 003 | DE-604 | ||
| 005 | 20250515 | ||
| 007 | t| | ||
| 008 | 250401s2025 xx a||| b||| 00||| eng d | ||
| 020 | |a 9780231216234 |9 978-0-231-21623-4 | ||
| 035 | |a (DE-599)BVBBV050229031 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-703 | ||
| 100 | 1 | |a Szabó, Csaba |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Unreliable |b bias, fraud, and the reproducibility crisis in biomedical research |c Csaba Szabo |
| 264 | 1 | |a New York |b Columbia University Press |c [2025] | |
| 300 | |a XI, 314 Seiten |b Illustrationen, Diagramme |c 24 cm | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 505 | 8 | |a Careers and career pressures in biomedical science -- Hypercompetition for research grants -- "Doing science" : from hypothesis to publication -- Scientific fraud -- and fraudulent fraudsters -- A broken scientific publishing system -- The way forward | |
| 520 | 3 | |a "Scientists specializing in the in-depth analysis of the published scientific literature have to the conclusion that a large part of the scientific literature covers results that cannot be replicated in other independent laboratories. Scientists take this to mean that the results are unreliable or untrue. In this book, biomedical researcher Csaba Szabo summarizes the causes and consequences of this so-called "reproducibility crisis" in biomedical research. The range of causes is wide, from the specificities of the methods used, through various pitfalls in the design of experiments and analysis of experimental data (e.g., confirmation bias), plagiarism and deliberate data falsification, to the systematic publication of fictitious experiments that have never been performed. Through a few blatant examples - e.g. Anil Potti (Duke University); Piero Anversa (Harvard University) - Szabo describes the damaging impact that blatant fraud can have on the development of an entire field of science, and introduces some of the maverick "science investigators" - often working in anonymity - who devote their lives to tracking down and exposing scientific fraudsters. The book also answers the questions (a) what individual and systemic factors are involved in allowing these phenomena to occur, (b) why the appropriate steps have not been taken to control them, and (c) what the implications of the crisis are for the future of medicine and, within it, for the development of new drugs"-- | |
| 653 | 0 | |a Reproducible research | |
| 653 | 0 | |a Fraud in science | |
| 653 | 0 | |a Reproducibility of Results | |
| 653 | 0 | |a Biomedical Research | |
| 653 | 0 | |a Bias | |
| 653 | 0 | |a Scientific Misconduct | |
| 653 | 0 | |a Reproductibilité (Sciences) | |
| 653 | 0 | |a Erreurs systématiques | |
| 653 | 0 | |a Fraude scientifique | |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-035563880 | |
Record in the Search Index
| _version_ | 1832195346200002560 |
|---|---|
| adam_text | |
| any_adam_object | |
| author | Szabó, Csaba |
| author_facet | Szabó, Csaba |
| author_role | aut |
| author_sort | Szabó, Csaba |
| author_variant | c s cs |
| building | Verbundindex |
| bvnumber | BV050229031 |
| contents | Careers and career pressures in biomedical science -- Hypercompetition for research grants -- "Doing science" : from hypothesis to publication -- Scientific fraud -- and fraudulent fraudsters -- A broken scientific publishing system -- The way forward |
| ctrlnum | (DE-599)BVBBV050229031 |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>00000nam a2200000 c 4500</leader><controlfield tag="001">BV050229031</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20250515</controlfield><controlfield tag="007">t|</controlfield><controlfield tag="008">250401s2025 xx a||| b||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780231216234</subfield><subfield code="9">978-0-231-21623-4</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV050229031</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-703</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Szabó, Csaba</subfield><subfield code="e">Verfasser</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Unreliable</subfield><subfield code="b">bias, fraud, and the reproducibility crisis in biomedical research</subfield><subfield code="c">Csaba Szabo</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">New York</subfield><subfield code="b">Columbia University Press</subfield><subfield code="c">[2025]</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XI, 314 Seiten</subfield><subfield code="b">Illustrationen, Diagramme</subfield><subfield code="c">24 cm</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">Careers and career pressures in biomedical science -- Hypercompetition for research grants -- "Doing science" : from hypothesis to publication -- Scientific fraud -- and fraudulent fraudsters -- A broken scientific publishing system -- The way forward</subfield></datafield><datafield tag="520" ind1="3" ind2=" "><subfield code="a">"Scientists specializing in the in-depth analysis of the published scientific literature have to the conclusion that a large part of the scientific literature covers results that cannot be replicated in other independent laboratories. Scientists take this to mean that the results are unreliable or untrue. In this book, biomedical researcher Csaba Szabo summarizes the causes and consequences of this so-called "reproducibility crisis" in biomedical research. The range of causes is wide, from the specificities of the methods used, through various pitfalls in the design of experiments and analysis of experimental data (e.g., confirmation bias), plagiarism and deliberate data falsification, to the systematic publication of fictitious experiments that have never been performed. Through a few blatant examples - e.g. Anil Potti (Duke University); Piero Anversa (Harvard University) - Szabo describes the damaging impact that blatant fraud can have on the development of an entire field of science, and introduces some of the maverick "science investigators" - often working in anonymity - who devote their lives to tracking down and exposing scientific fraudsters. The book also answers the questions (a) what individual and systemic factors are involved in allowing these phenomena to occur, (b) why the appropriate steps have not been taken to control them, and (c) what the implications of the crisis are for the future of medicine and, within it, for the development of new drugs"--</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Reproducible research</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Fraud in science</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Reproducibility of Results</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Biomedical Research</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Bias</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Scientific Misconduct</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Reproductibilité (Sciences)</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Erreurs systématiques</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Fraude scientifique</subfield></datafield><datafield tag="943" ind1="1" ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-035563880</subfield></datafield></record></collection> |
| id | DE-604.BV050229031 |
| illustrated | Illustrated |
| indexdate | 2025-05-15T14:00:44Z |
| institution | BVB |
| isbn | 9780231216234 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-035563880 |
| open_access_boolean | |
| owner | DE-703 |
| owner_facet | DE-703 |
| physical | XI, 314 Seiten Illustrationen, Diagramme 24 cm |
| publishDate | 2025 |
| publishDateSearch | 2025 |
| publishDateSort | 2025 |
| publisher | Columbia University Press |
| record_format | marc |
| spelling | Szabó, Csaba Verfasser aut Unreliable bias, fraud, and the reproducibility crisis in biomedical research Csaba Szabo New York Columbia University Press [2025] XI, 314 Seiten Illustrationen, Diagramme 24 cm txt rdacontent n rdamedia nc rdacarrier Careers and career pressures in biomedical science -- Hypercompetition for research grants -- "Doing science" : from hypothesis to publication -- Scientific fraud -- and fraudulent fraudsters -- A broken scientific publishing system -- The way forward "Scientists specializing in the in-depth analysis of the published scientific literature have to the conclusion that a large part of the scientific literature covers results that cannot be replicated in other independent laboratories. Scientists take this to mean that the results are unreliable or untrue. In this book, biomedical researcher Csaba Szabo summarizes the causes and consequences of this so-called "reproducibility crisis" in biomedical research. The range of causes is wide, from the specificities of the methods used, through various pitfalls in the design of experiments and analysis of experimental data (e.g., confirmation bias), plagiarism and deliberate data falsification, to the systematic publication of fictitious experiments that have never been performed. Through a few blatant examples - e.g. Anil Potti (Duke University); Piero Anversa (Harvard University) - Szabo describes the damaging impact that blatant fraud can have on the development of an entire field of science, and introduces some of the maverick "science investigators" - often working in anonymity - who devote their lives to tracking down and exposing scientific fraudsters. The book also answers the questions (a) what individual and systemic factors are involved in allowing these phenomena to occur, (b) why the appropriate steps have not been taken to control them, and (c) what the implications of the crisis are for the future of medicine and, within it, for the development of new drugs"-- Reproducible research Fraud in science Reproducibility of Results Biomedical Research Bias Scientific Misconduct Reproductibilité (Sciences) Erreurs systématiques Fraude scientifique |
| spellingShingle | Szabó, Csaba Unreliable bias, fraud, and the reproducibility crisis in biomedical research Careers and career pressures in biomedical science -- Hypercompetition for research grants -- "Doing science" : from hypothesis to publication -- Scientific fraud -- and fraudulent fraudsters -- A broken scientific publishing system -- The way forward |
| title | Unreliable bias, fraud, and the reproducibility crisis in biomedical research |
| title_alt | Bias, fraud, and the reproducibility crisis in biomedical research |
| title_auth | Unreliable bias, fraud, and the reproducibility crisis in biomedical research |
| title_exact_search | Unreliable bias, fraud, and the reproducibility crisis in biomedical research |
| title_full | Unreliable bias, fraud, and the reproducibility crisis in biomedical research Csaba Szabo |
| title_fullStr | Unreliable bias, fraud, and the reproducibility crisis in biomedical research Csaba Szabo |
| title_full_unstemmed | Unreliable bias, fraud, and the reproducibility crisis in biomedical research Csaba Szabo |
| title_short | Unreliable |
| title_sort | unreliable bias fraud and the reproducibility crisis in biomedical research |
| title_sub | bias, fraud, and the reproducibility crisis in biomedical research |
| work_keys_str_mv | AT szabocsaba unreliablebiasfraudandthereproducibilitycrisisinbiomedicalresearch |