The Power of Prions: The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases
The remarkable family of proteins that can make us very ill-but can also be linked to long-term memory, immunity, and the origin of lifeOver the last decade, scientists have discovered the importance and widespread presence in the body of a remarkable family of proteins known as prion proteins. Rese...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
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Princeton, NJ
Princeton University Press
[2024]
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| Zusammenfassung: | The remarkable family of proteins that can make us very ill-but can also be linked to long-term memory, immunity, and the origin of lifeOver the last decade, scientists have discovered the importance and widespread presence in the body of a remarkable family of proteins known as prion proteins. Research links various types of prion proteins to neurodegenerative diseases such as Parkinson's and Alzheimer's-and this has fueled the search for new drugs that could halt the progression of these terrible disorders. Other discoveries have revealed the essential roles prion proteins play in memory and immunity, and-in an extraordinary finding-the part they may have played in the beginnings of life on our planet. In this engaging and accessible book, Michel Brahic tells the story of these amazing and versatile proteins.Brahic, a leading researcher on diseases of the central nervous system, first describes the discovery of prions and their role in infection, beginning with early work on the animal disease scrapie and a mysterious human illness in New Guinea, apparently transmitted by cannibalism. Prions were eventually identified and named by Stanley Prusiner in the 1980s. (Brahic tells us Prusiner's alternate name for prion was "piaf.") Prion proteins were then revealed as the cause of other illnesses, from "mad cow" disease and its human counterpart, Creutzfeldt-Jakob disease, to such noninfectious brain disorders as Parkinson's and Alzheimer's. While the prion proteins responsible for diseases are definitively "bad," Brahic also explains that these abnormal prions are rare exceptions. Most of the time, prion proteins actually serve "good" and vital functions-and they may even have been present at the origin of life itself |
| Beschreibung: | Description based on online resource; title from PDF title page (publisher's Web site, viewed 20. Nov 2024) |
| Beschreibung: | 1 Online-Ressource (192 pages) 11 b/w illus |
| ISBN: | 9780691252407 |
| DOI: | 10.1515/9780691252407 |
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| 520 | |a The remarkable family of proteins that can make us very ill-but can also be linked to long-term memory, immunity, and the origin of lifeOver the last decade, scientists have discovered the importance and widespread presence in the body of a remarkable family of proteins known as prion proteins. Research links various types of prion proteins to neurodegenerative diseases such as Parkinson's and Alzheimer's-and this has fueled the search for new drugs that could halt the progression of these terrible disorders. Other discoveries have revealed the essential roles prion proteins play in memory and immunity, and-in an extraordinary finding-the part they may have played in the beginnings of life on our planet. In this engaging and accessible book, Michel Brahic tells the story of these amazing and versatile proteins.Brahic, a leading researcher on diseases of the central nervous system, first describes the discovery of prions and their role in infection, beginning with early work on the animal disease scrapie and a mysterious human illness in New Guinea, apparently transmitted by cannibalism. Prions were eventually identified and named by Stanley Prusiner in the 1980s. (Brahic tells us Prusiner's alternate name for prion was "piaf.") Prion proteins were then revealed as the cause of other illnesses, from "mad cow" disease and its human counterpart, Creutzfeldt-Jakob disease, to such noninfectious brain disorders as Parkinson's and Alzheimer's. While the prion proteins responsible for diseases are definitively "bad," Brahic also explains that these abnormal prions are rare exceptions. Most of the time, prion proteins actually serve "good" and vital functions-and they may even have been present at the origin of life itself | ||
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| spelling | Brahic, Michel Verfasser aut The Power of Prions The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases Michel Brahic Princeton, NJ Princeton University Press [2024] 2024 1 Online-Ressource (192 pages) 11 b/w illus txt rdacontent c rdamedia cr rdacarrier Description based on online resource; title from PDF title page (publisher's Web site, viewed 20. Nov 2024) The remarkable family of proteins that can make us very ill-but can also be linked to long-term memory, immunity, and the origin of lifeOver the last decade, scientists have discovered the importance and widespread presence in the body of a remarkable family of proteins known as prion proteins. Research links various types of prion proteins to neurodegenerative diseases such as Parkinson's and Alzheimer's-and this has fueled the search for new drugs that could halt the progression of these terrible disorders. Other discoveries have revealed the essential roles prion proteins play in memory and immunity, and-in an extraordinary finding-the part they may have played in the beginnings of life on our planet. In this engaging and accessible book, Michel Brahic tells the story of these amazing and versatile proteins.Brahic, a leading researcher on diseases of the central nervous system, first describes the discovery of prions and their role in infection, beginning with early work on the animal disease scrapie and a mysterious human illness in New Guinea, apparently transmitted by cannibalism. Prions were eventually identified and named by Stanley Prusiner in the 1980s. (Brahic tells us Prusiner's alternate name for prion was "piaf.") Prion proteins were then revealed as the cause of other illnesses, from "mad cow" disease and its human counterpart, Creutzfeldt-Jakob disease, to such noninfectious brain disorders as Parkinson's and Alzheimer's. While the prion proteins responsible for diseases are definitively "bad," Brahic also explains that these abnormal prions are rare exceptions. Most of the time, prion proteins actually serve "good" and vital functions-and they may even have been present at the origin of life itself In English SCIENCE / Life Sciences / Neuroscience bisacsh Nervous system Degeneration Nervous system Diseases Prion diseases Prions https://doi.org/10.1515/9780691252407?locatt=mode:legacy Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Brahic, Michel The Power of Prions The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases SCIENCE / Life Sciences / Neuroscience bisacsh Nervous system Degeneration Nervous system Diseases Prion diseases Prions |
| title | The Power of Prions The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases |
| title_auth | The Power of Prions The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases |
| title_exact_search | The Power of Prions The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases |
| title_full | The Power of Prions The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases Michel Brahic |
| title_fullStr | The Power of Prions The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases Michel Brahic |
| title_full_unstemmed | The Power of Prions The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases Michel Brahic |
| title_short | The Power of Prions |
| title_sort | the power of prions the strange and essential proteins that can cause alzheimer s parkinson s and other diseases |
| title_sub | The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases |
| topic | SCIENCE / Life Sciences / Neuroscience bisacsh Nervous system Degeneration Nervous system Diseases Prion diseases Prions |
| topic_facet | SCIENCE / Life Sciences / Neuroscience Nervous system Degeneration Nervous system Diseases Prion diseases Prions |
| url | https://doi.org/10.1515/9780691252407?locatt=mode:legacy |
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