Enzymes and drugs:
Cover -- Title Page -- Contents -- Preface -- Introduction -- Chapter 1. Enzyme Kinetics, Inhibition and Activation -- 1.1. Michaelis and Menten theory -- 1.2. Irreversible inhibitors -- 1.3. Reversible inhibitors in a Michaelian system -- 1.3.1. Reversible competitive inhibitors -- 1.3.2. Reversibl...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
London, UK
ISTE Ltd
2024
Hoboken, NJ Wiley |
| Schriftenreihe: | Chemistry series
|
| Schlagworte: | |
| Online-Zugang: | DE-91 |
| Zusammenfassung: | Cover -- Title Page -- Contents -- Preface -- Introduction -- Chapter 1. Enzyme Kinetics, Inhibition and Activation -- 1.1. Michaelis and Menten theory -- 1.2. Irreversible inhibitors -- 1.3. Reversible inhibitors in a Michaelian system -- 1.3.1. Reversible competitive inhibitors -- 1.3.2. Reversible non-competitive inhibitors -- 1.3.3. Reversible uncompetitive inhibitors -- 1.4. Allostery: inhibitors and activators -- 1.4.1. Allosteric enzyme kinetics -- 1.4.2. Mechanism of allosteric enzyme regulation -- 1.5. References -- Chapter 2. Targeted Viral and Microbial Enzymes -- 2.1. Viral targets -- 2.1.1. Herpes group viruses: DNA-dependent DNA polymerases (EC 2) -- 2.1.2. Influenza virus: exo-alpha-sialidase or neuraminidase (EC 3) -- 2.1.3. HIV protease (EC 3) -- 2.1.4. HIV reverse transcriptase (RNA/DNA-dependent DNA polymerase - EC 2) -- 2.1.5. HIV integrase (EC 2) -- 2.1.6. Hepatitis C virus (HCV): RNA-dependent RNA polymerase (NS5B - EC 2) and viral protease (NS3-4A - EC 3) -- 2.2. Bacterial targets -- 2.2.1. Specific target (action mainly focused on the Mycobacterium tuberculosis species) -- 2.2.2. General actions -- 2.3. Fungal targets -- 2.3.1. 1,3-beta-glucan synthase (EC 2) -- 2.3.2. Squalene mono-oxygenase (EC 1) -- 2.3.3. 14-sterol demethylase (EC 1) -- 2.3.4. Thymidylate synthase (EC 2) -- 2.4. Parasite targets -- 2.4.1. Ornithine decarboxylase (EC 4) -- 2.4.2. Heme polymerase (EC 2) -- 2.5. References -- Chapter 3. Targeted Human Enzymes -- 3.1. Treatment via effectors -- 3.1.1. Ophthalmology -- 3.1.2. Neurology -- 3.1.3. Metabolism and endocrinology -- 3.1.4. Cardiovascular and immunology -- 3.1.5. Oncology -- 3.1.6. Phosphatome and Kinome -- 3.2. Enzyme replacement therapy -- 3.2.1. Gout -- 3.2.2. Acute leukemia and non-Hodgkin's lymphoma -- 3.2.3. Hypophosphatasia -- 3.2.4. Chronic obstructive pulmonary disease -- 3.3. References. |
| Beschreibung: | Online-Ressource Illustrationen, Diagramme |
| ISBN: | 9781394299072 9781394299089 |
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| 520 | 3 | |a Cover -- Title Page -- Contents -- Preface -- Introduction -- Chapter 1. Enzyme Kinetics, Inhibition and Activation -- 1.1. Michaelis and Menten theory -- 1.2. Irreversible inhibitors -- 1.3. Reversible inhibitors in a Michaelian system -- 1.3.1. Reversible competitive inhibitors -- 1.3.2. Reversible non-competitive inhibitors -- 1.3.3. Reversible uncompetitive inhibitors -- 1.4. Allostery: inhibitors and activators -- 1.4.1. Allosteric enzyme kinetics -- 1.4.2. Mechanism of allosteric enzyme regulation -- 1.5. References -- Chapter 2. Targeted Viral and Microbial Enzymes -- 2.1. Viral targets -- 2.1.1. Herpes group viruses: DNA-dependent DNA polymerases (EC 2) -- 2.1.2. Influenza virus: exo-alpha-sialidase or neuraminidase (EC 3) -- 2.1.3. HIV protease (EC 3) -- 2.1.4. HIV reverse transcriptase (RNA/DNA-dependent DNA polymerase - EC 2) -- 2.1.5. HIV integrase (EC 2) -- 2.1.6. Hepatitis C virus (HCV): RNA-dependent RNA polymerase (NS5B - EC 2) and viral protease (NS3-4A - EC 3) -- 2.2. Bacterial targets -- 2.2.1. Specific target (action mainly focused on the Mycobacterium tuberculosis species) -- 2.2.2. General actions -- 2.3. Fungal targets -- 2.3.1. 1,3-beta-glucan synthase (EC 2) -- 2.3.2. Squalene mono-oxygenase (EC 1) -- 2.3.3. 14-sterol demethylase (EC 1) -- 2.3.4. Thymidylate synthase (EC 2) -- 2.4. Parasite targets -- 2.4.1. Ornithine decarboxylase (EC 4) -- 2.4.2. Heme polymerase (EC 2) -- 2.5. References -- Chapter 3. Targeted Human Enzymes -- 3.1. Treatment via effectors -- 3.1.1. Ophthalmology -- 3.1.2. Neurology -- 3.1.3. Metabolism and endocrinology -- 3.1.4. Cardiovascular and immunology -- 3.1.5. Oncology -- 3.1.6. Phosphatome and Kinome -- 3.2. Enzyme replacement therapy -- 3.2.1. Gout -- 3.2.2. Acute leukemia and non-Hodgkin's lymphoma -- 3.2.3. Hypophosphatasia -- 3.2.4. Chronic obstructive pulmonary disease -- 3.3. References. | |
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Datensatz im Suchindex
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| id | DE-604.BV049753432 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-20T07:56:58Z |
| institution | BVB |
| isbn | 9781394299072 9781394299089 |
| language | English |
| oclc_num | 1443579939 |
| open_access_boolean | |
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| owner_facet | DE-91G DE-BY-TUM |
| physical | Online-Ressource Illustrationen, Diagramme |
| psigel | ZDB-30-PQE ZDB-30-PQE TUM_Einzelkauf_2024 |
| publishDate | 2024 |
| publishDateSearch | 2024 |
| publishDateSort | 2024 |
| publisher | ISTE Ltd Wiley |
| record_format | marc |
| series2 | Chemistry series |
| spelling | Kirkiacharian, Serge Verfasser aut Enzymes and drugs Serge Kirkiacharian, Julien Dumond London, UK ISTE Ltd 2024 Hoboken, NJ Wiley Online-Ressource Illustrationen, Diagramme txt rdacontent c rdamedia cr rdacarrier Chemistry series Cover -- Title Page -- Contents -- Preface -- Introduction -- Chapter 1. Enzyme Kinetics, Inhibition and Activation -- 1.1. Michaelis and Menten theory -- 1.2. Irreversible inhibitors -- 1.3. Reversible inhibitors in a Michaelian system -- 1.3.1. Reversible competitive inhibitors -- 1.3.2. Reversible non-competitive inhibitors -- 1.3.3. Reversible uncompetitive inhibitors -- 1.4. Allostery: inhibitors and activators -- 1.4.1. Allosteric enzyme kinetics -- 1.4.2. Mechanism of allosteric enzyme regulation -- 1.5. References -- Chapter 2. Targeted Viral and Microbial Enzymes -- 2.1. Viral targets -- 2.1.1. Herpes group viruses: DNA-dependent DNA polymerases (EC 2) -- 2.1.2. Influenza virus: exo-alpha-sialidase or neuraminidase (EC 3) -- 2.1.3. HIV protease (EC 3) -- 2.1.4. HIV reverse transcriptase (RNA/DNA-dependent DNA polymerase - EC 2) -- 2.1.5. HIV integrase (EC 2) -- 2.1.6. Hepatitis C virus (HCV): RNA-dependent RNA polymerase (NS5B - EC 2) and viral protease (NS3-4A - EC 3) -- 2.2. Bacterial targets -- 2.2.1. Specific target (action mainly focused on the Mycobacterium tuberculosis species) -- 2.2.2. General actions -- 2.3. Fungal targets -- 2.3.1. 1,3-beta-glucan synthase (EC 2) -- 2.3.2. Squalene mono-oxygenase (EC 1) -- 2.3.3. 14-sterol demethylase (EC 1) -- 2.3.4. Thymidylate synthase (EC 2) -- 2.4. Parasite targets -- 2.4.1. Ornithine decarboxylase (EC 4) -- 2.4.2. Heme polymerase (EC 2) -- 2.5. References -- Chapter 3. Targeted Human Enzymes -- 3.1. Treatment via effectors -- 3.1.1. Ophthalmology -- 3.1.2. Neurology -- 3.1.3. Metabolism and endocrinology -- 3.1.4. Cardiovascular and immunology -- 3.1.5. Oncology -- 3.1.6. Phosphatome and Kinome -- 3.2. Enzyme replacement therapy -- 3.2.1. Gout -- 3.2.2. Acute leukemia and non-Hodgkin's lymphoma -- 3.2.3. Hypophosphatasia -- 3.2.4. Chronic obstructive pulmonary disease -- 3.3. References. Enzym (DE-588)4014988-2 gnd rswk-swf Arzneimittel (DE-588)4003115-9 gnd rswk-swf Enzym (DE-588)4014988-2 s Arzneimittel (DE-588)4003115-9 s DE-604 Dumond, Julien Verfasser aut Erscheint auch als Druck-Ausgabe 978-1-78630-939-6 |
| spellingShingle | Kirkiacharian, Serge Dumond, Julien Enzymes and drugs Enzym (DE-588)4014988-2 gnd Arzneimittel (DE-588)4003115-9 gnd |
| subject_GND | (DE-588)4014988-2 (DE-588)4003115-9 |
| title | Enzymes and drugs |
| title_auth | Enzymes and drugs |
| title_exact_search | Enzymes and drugs |
| title_full | Enzymes and drugs Serge Kirkiacharian, Julien Dumond |
| title_fullStr | Enzymes and drugs Serge Kirkiacharian, Julien Dumond |
| title_full_unstemmed | Enzymes and drugs Serge Kirkiacharian, Julien Dumond |
| title_short | Enzymes and drugs |
| title_sort | enzymes and drugs |
| topic | Enzym (DE-588)4014988-2 gnd Arzneimittel (DE-588)4003115-9 gnd |
| topic_facet | Enzym Arzneimittel |
| work_keys_str_mv | AT kirkiacharianserge enzymesanddrugs AT dumondjulien enzymesanddrugs |