DNA nanotechnology for cell research: from bioanalysis to biomedicine
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| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Weinheim, Germany
Wiley-VCH
[2024]
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| Schlagworte: | |
| Online-Zugang: | http://www.wiley-vch.de/publish/dt/books/ISBN978-3-527-35173-2/ Inhaltsverzeichnis |
| Beschreibung: | xvi, 528 Seiten Illustrationen, Diagramme 24.4 cm x 17 cm, 1182 g |
| ISBN: | 9783527351732 3527351736 |
Internformat
MARC
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| 020 | |a 3527351736 |9 3-527-35173-6 | ||
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| 024 | 3 | |a 9783527351732 | |
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| 084 | |8 1\p |a 540 |2 23sdnb | ||
| 245 | 1 | 0 | |a DNA nanotechnology for cell research |b from bioanalysis to biomedicine |c edited by Zhou Nie |
| 264 | 1 | |a Weinheim, Germany |b Wiley-VCH |c [2024] | |
| 300 | |a xvi, 528 Seiten |b Illustrationen, Diagramme |c 24.4 cm x 17 cm, 1182 g | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 0 | 7 | |a Nanotechnologie |0 (DE-588)4327470-5 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Cytologie |0 (DE-588)4070177-3 |2 gnd |9 rswk-swf |
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| 650 | 0 | 7 | |a DNS |0 (DE-588)4070512-2 |2 gnd |9 rswk-swf |
| 653 | |a Biomolecules (DNA, RNA, Peptides, etc.) | ||
| 653 | |a Biomoleküle (DNA, RNA, Peptide) | ||
| 653 | |a Biotechnologie i. d. Biowissenschaften | ||
| 653 | |a Biotechnology | ||
| 653 | |a Biowissenschaften | ||
| 653 | |a Chemie | ||
| 653 | |a Chemistry | ||
| 653 | |a Life Sciences | ||
| 653 | |a Nanobiotechnologie | ||
| 653 | |a Nanobiotechnology | ||
| 653 | |a Nanotechnologie | ||
| 653 | |a Nanotechnology | ||
| 653 | |a CHB1: Biomoleküle (DNA, RNA, Peptide) | ||
| 653 | |a LS35: Biotechnologie i. d. Biowissenschaften | ||
| 653 | |a NT50: Nanobiotechnologie | ||
| 653 | |a Biotechnologie | ||
| 653 | |a DNA | ||
| 653 | |a DNS | ||
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| 689 | 0 | 1 | |a Nanotechnologie |0 (DE-588)4327470-5 |D s |
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| 700 | 1 | |a Nie, Zhou |0 (DE-588)132732525X |4 edt | |
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| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-034975743 | |
Datensatz im Suchindex
| _version_ | 1810687939155329024 |
|---|---|
| adam_text |
CONTENTS
PREFACE
XV
PART
I
DNA
NANOTECHNOLOGY
FOR
CELLULAR
RECOGNITION
(CELL
SELEX,
CELL
SURFACE
ENGINEERING)
1
1
DEVELOPING
DNA
APTAMER
TOOLBOX
FOR
CELL
RESEARCH
3
LIANG
YUE,
SHAN
WANG,
AND
WEIHONG
TAN
1.1
CELLS
AND
THEIR
COMPLEXITY
3
1.2
FEATURES
AND
ADVANTAGES
OF
DNA
APTAMERS
4
1.3
ON-DEMAND
SYNTHESIS
AND
SCREENING
OF
DNA
APTAMERS
5
1.4
TOWARD
A
TOOLBOX
OF
DNA
APTAMERS
FOR
CELLULAR
APPLICATIONS
9
1.4.1
CHEMICAL
MODIFICATIONS
VIA
SOLID-SUPPORTED
SYNTHESIS
STRATEGY
10
1.4.2
CHEMICAL
MODIFICATIONS
THROUGH
COVALENT
CONJUGATION
13
1.4.3
SELF-ASSEMBLY
SYSTEMS
BASED
ON
CHEMICALLY
MODIFIED
DNA
APTAMERS
15
1.4.4
DNA
APTAMERS
ENGINEERED
WITH
NANOTECHNOLOGY
19
1.5
SUMMARY
AND
OUTLOOK
21
ACKNOWLEDGMENTS
22
REFERENCES
22
2
BACTERIAL
DETECTION
WITH
FUNCTIONAL
NUCLEIC
ACIDS:
ESCHERICHIA
COLI
AS
A
CASE
STUDY
31
YASH
PATEL
AND
YINGFU
LI
2.1
GENERAL
INTRODUCTION
TO
BACTERIA
31
2.2
E.COLI
32
2.3
CONVENTIONAL
METHODS
FOR
GENERAL
E.
COLI
DETECTION
33
2.3.1
SORBITOL
MACCONKEY
AGAR
34
2.3.2
PCR
34
2.4
BIOSENSORS
FOR
E.
COLI
DETECTION
35
2.4.1
PROTEIN
BIOSENSORS
FOR
E.
COLI
DETECTION
35
2.4.2
FUNCTIONAL
NUCLEIC
ACID-BASED
SENSORS
FOR
E.
COLI
DETECTION
36
2.4.2.1
DNAZYME-BASED
BIOSENSORS
FOR
E.
COLI
DETECTION
36
VI
|
CONTENTS
2.4.2.2
2.5
APTAMER-BASED
SENSORS
FOR
E.
COLI
DETECTION
39
CONCLUSION
41
REFERENCES
42
3
FROM
LIGAND-BINDING
APTAMERS
TO
MOLECULAR
SWITCHES
47
SANSHU
LI,
XIAOJUN
ZHANG,
TAO
LUO,
XUEJIAO
LIU,
TINGTING
ZHAI,
AND
HONGZHOU
GU
3.1
3.2
3.3
APTAMERS
CAN
BE
GENERATED
BY
SELEX
47
VARIOUS
SUBTYPES
OF
SELEX
HAVE
BEEN
INVENTED
48
RIBOSWITCHES
ARE
NATURAL
RNA
APTAMERS
CARRYING
EXPRESSION
PLATFORMS
49
3.4
3.5
3.6
RIBOSWITCHES
USE
VARIOUS
MECHANISMS
TO
REGULATE
GENE
EXPRESSION
52
RIBOSWITCHES
ARE
POTENTIAL
DRUG
TARGETS
55
FUSING
APTAMER
WITH
EXPRESSION
PLATFORM
TO
CONSTRUCT
ARTIFICIAL
RNA
SWITCHES
55
3.7
CONCLUSIONS
57
ACKNOWLEDGMENTS
57
REFERENCES
57
4
DNA
NANOTECHNOLOGY-BASED
MICROFLUIDICS
FOR
LIQUID
BIOPSY
63
QI
NIU,
SHANQING
HUANG,
CHAOYONG
YANG,
AND
LINGLING
WU
4.1
4.2
INTRODUCTION
63
DNA
NANOTECHNOLOGY-BASED MICROFLUIDICS
FOR
ISOLATION
OF
CIRCULATING
TARGETS
65
4.2.1
4.2.1.1
4.2.1.2
4.2.1.3
4.2.2
4.2.2.1
4.2.2.2
4.3
APTAMER-MODIFIED
MICRO/NANO-SUBSTRATE
MICROFLUIDIC CHIP
65
INORGANIC
NANOSTRUCTURED
"
HARD
SUBSTRATES
"
66
ORGANIC
NANOSTRUCTURED
"
SOFT
SUBSTRATES
"
66
MULTIVALENT
APTAMER-FUNCTIONALIZED
MICRO/NANO-SUBSTRATES
69
DNA
FRAMEWORK-SUPPORTED
AFFINITY
SUBSTRATE
MICROFLUIDIC
CHIP
73
DNA
FRAMEWORK-SUPPORTED
APTAMER
SUBSTRATES
73
DNA
FRAMEWORK-SUPPORTED
ANTIBODY
SUBSTRATES
75
DNA
NANOTECHNOLOGY-BASED
MICROFLUIDICS
FOR
RELEASE
AND
DETECTION
OF
CIRCULATING
TARGETS
77
4.3.1
4.3.1.1
4.3.1.2
4.3.2
4.3.2.1
4.3.2.2
4.3.3
4.3.3.1
4.3.3.2
4.4
4.4.1
EFFICIENT
RELEASE
77
APTAMER
CONFORMATION
ALTERATION
77
DETACHING
APTAMERS
FROM
CAPTURE
INTERFACE
79
ANALYSIS
AND
DESTRUCTION
OF
CTCS
81
CTC
DETECTION
AND
IN-DEPTH
ANALYSIS
81
CTC
DESTRUCTION
FOR
THERAPY
83
SENSITIVE
DETECTION
OF
EVS
85
SIGNAL
TRANSDUCTION
FOR
EV
DETECTION
85
SIGNAL
AMPLIFICATION
85
DNA-ASSISTED
MICROFLUIDICS
FOR
SINGLE-CELL/VESICLE
ANALYSIS
88
SINGLE-CELL
ANALYSIS
BY
SEQUENCING
89
CONTENTS
VII
4.4.2
4.4.3
4.5
SINGLE-CELL
ANALYSIS
BY
SPECTROSCOPY
93
SINGLE-VESICLE
ANALYSIS
95
SUMMARY
AND
OUTLOOK
97
REFERENCES
98
5
SPATIOTEMPORAL-CONTROLLED
CELL
MEMBRANE
ENGINEERING
USING
DNA
NANOTECHNOLOGY
105
WENXUE
XIE,
CONG
REN,
MINJIE
LIN,
AND
HANG
XING
5.1
5.2
5.2.1
BACKGROUND
105
DNA
MODIFICATIONS
ON
THE
EXTERNAL
CELL
MEMBRANE
SURFACE
107
STRATEGIES
TO
INCORPORATE
DNA
ONTO
EXTERNAL
CELL
MEMBRANE
SURFACE
107
5.2.1.1
5.2.1.2
5.2.2
5.2.2.1
5.2.2.2
5.2.2.3
5.3
5.3.1
5.3.1.1
NONSPECIFIC
DNA
MODIFICATION
STRATEGIES
107
SPECIFIC
DNA
MODIFICATION
STRATEGIES
111
APPLICATIONS
OF
EXTERNAL
MEMBRANE-MODIFIED
DNA
114
SENSING
AND
IMAGING
ON
CELL
MEMBRANE
USING
DNA
PROBES
114
DNA-MEDIATED
CELL
ASSEMBLY
AND
COMMUNICATION
117
CELL
PROTECTION
USING
DNA
STRUCTURES
ON
MEMBRANE
119
DNA
MODIFICATIONS
ON
THE
INTERNAL
CELL
MEMBRANE
SURFACE
120
TRANSMEMBRANE
MODIFICATION
OF
DNA
121
TRANSMEMBRANE
MODIFICATION
USING
SINGLE-STRANDED
AND
DOUBLE-STRANDED
DNA
121
5.3.1.2
5.3.2
5.3.2.1
5.3.2.2
5.3.3
5.4
TRANSMEMBRANE
MODIFICATION
USING
DNA
NANOSTRUCTURES
122
INNER
LEAFLET
MODIFICATION
APPROACHES
124
SMALL-MOLECULE
LIGAND
TARGETING
APPROACH
125
CELL-PENETRATING
PEPTIDE
APPROACH
127
LIPOSOME
FUSION-BASED
TRANSPORT
(LIFT)
APPROACH
129
PERSPECTIVES
130
ACKNOWLEDGMENTS
132
REFERENCES
132
PART
II
DNA
NANOTECHNOLOGY
FOR
CELL
IMAGING
AND
INTRACELLULAR
SENSING
141
6
METAL-DEPENDENT
DNAZYMES
FOR
CELL
SURFACE
ENGINEERING
AND
INTRACELLULAR
BIOIMAGING
143
RUO-CAN
QIAN,
YUTING
WU,
ZHENGLIN
YANG,
WEIJIE
GUO,
ZE-RUI
ZHOU,
AND
YI
LU
6.1
CELLULAR
SURFACE
ENGINEERING
AND
INTRACELLULAR
BIOIMAGING
SHOW
GREAT
POTENTIAL
IN
BIOLOGICAL
AND
MEDICAL
RESEARCH
143
6.2
METAL-SPECIFIC
DNAZYMES:
A
SUITABLE
CHOICE
FOR
ARTIFICIAL
MANIPULATION
OF
LIVING
CELLS
144
6.3
6.3.1
CELL
SURFACE
ENGINEERING
BY
PROGRAMMABLE
DNAZYMES
145
CELL
SURFACE
ENGINEERING
USING
DNAZYME-BASED
CONTROL
SWITCHES
145
VIII
|
CONTENTS
6.3.2
DYNAMIC
INTER
AND
INTRA-CELLULAR
REGULATION
USING
ENGINEERED
DNAZYME
MOLECULAR
MACHINES
147
6.3.3
CELL
SURFACE
IMAGING
OF
EXTRACELLULAR
SIGNALING
MOLECULE
USING
DNAZYME
SENSORS
149
6.4
INTRACELLULAR
IMAGING
OF
METAL
IONS
WITH
DNAZYME-BASED
BIOSENSORS
150
6.4.1
DNAZYME-BASED
CATALYTIC
BEACON
FOR
INTRACELLULAR
IMAGING
150
6.4.2
CAGED
DNAZYMES
FOR
TEMPORALLY
CONTROLLED
IMAGING
154
6.4.3
DNAZYME-BASED
SENSING
WITH
SIGNAL
AMPLIFICATION
159
6.4.4
GENETICALLY
ENCODED
SENSORS
FOR
METAL
SENSING
IN
LIVING
CELLS
159
6.5
CONCLUSION
161
ACKNOWLEDGMENTS
161
REFERENCES
161
7
DNA
NANOMOTORS
FOR
BIOIMAGING
IN
LIVING
CELLS
169
HANYONG
PENG,
AIJIAO
YUAN,
HANG
XIAO,
ZI
YE,
LEJUN
LIAO,
SHULIN
ZHAO,
AND
X.
CHRIS
LE
REFERENCES
184
8
ILLUMINATING
RNA
IN
LIVE
CELLS
WITH
INORGANIC
NANOPARTICLES-BASED
DNA
SENSOR
TECHNOLOGY
189
FANGZHI
YU,
XIANGFEI
LI,
XIULIN
YI,
AND
LELE
LI
8.1
RNA
DETECTION
AND
IMAGING
189
8.2
RNA
IMAGING
BASED
ON
DIRECT
HYBRIDIZATION
190
8.3
RNA
IMAGING
BASED
ON
STRAND
DISPLACEMENT
REACTIONS
192
8.4
SIGNAL-AMPLIFIED
RNA
IMAGING
194
8.4.1
HCR-BASED
DNA
NANOSENSORS
FOR
AMPLIFIED
RNA
IMAGING
194
8.4.2
CHA-BASED
DNA
NANOSENSORS
FOR
AMPLIFIED
RNA
IMAGING
196
8.4.3
AMPLIFIED
RNA
IMAGING
BASED
ON
DNA
NANOMACHINES
198
8.5
SPATIOTEMPORALLY
CONTROLLED
RNA
IMAGING
IN
LIVE
CELLS
203
8.6
CONCLUSION
206
ACKNOWLEDGMENT
207
REFERENCES
207
9
BUILDING
DNA
COMPUTING
SYSTEM
FOR
SMART
BIOSENSING
AND
CLINICAL
DIAGNOSIS
211
JIAO
YANG
AND
DA
HAN
9.1
DNA
COMPUTING
211
9.1.1
DNA
LOGIC
GATES
BASED
ON
FUNCTIONAL
DNA
MOTIFS
212
9.1.2
DNA
LOGIC
GATES
BASED
ON
DNA
CASCADING
REACTIONS
215
9.2
DNA-BASED
COMPUTING
DEVICES
FOR
BIOSENSING
217
9.2.1
IN
VITRO
BIOSENSING
217
9.2.2
CELLULAR
BIOSENSING
220
CONTENTS
|
IX
9.3
DNA
COMPUTING
FOR
CLINICAL
DIAGNOSIS
223
9.4
CONCLUSION
226
REFERENCES
226
10
INTELLIGENT
SENSE-ON-DEMAND
DNA
CIRCUITS
FOR
AMPLIFIED
BIOIMAGING
IN
LIVING
CELLS
233
YUQIU
HE,
ZEYUE
WANG,
YUQIAN
JIANG,
AND
FUAN
WANG
10.1
DNA
CIRCUIT:
THE
PROMISING
TECHNIQUE
FOR
BIOIMAGING
233
10.2
NONENZYMATIC
DNA
CIRCUITS
234
10.2.1
HYBRIDIZATION
CHAIN
REACTION
(HCR)
234
10.2.2
CATALYTIC
HAIRPIN
ASSEMBLY
(CHA)
235
10.2.3
ENTROPY-DRIVEN
DNA
CATALYTIC
REACTION
(EDR)
236
10.2.4
DNAZYME-POWERED
CATALYTIC
REACTION
(DZR)
236
10.3
INTELLIGENT
INTEGRATED
DNA
CIRCUITS
FOR
AMPLIFIED
BIOIMAGING
237
10.3.1
HYBRIDIZATION-DEPENDENT
CASCADE
DNA
CIRCUITS
237
10.3.2
DNAZYME-ASSISTED
TANDEM
DNA
CIRCUITS
239
10.3.3
AUTOCATALYSIS-DRIVEN
FEEDBACK
DNA
CIRCUITS
241
10.4
STIMULI-RESPONSIVE
DNA
CIRCUITS
FOR
RELIABLE
BIOIMAGING
243
10.4.1
PHOTO-RESPONSIVE
DNA
CIRCUITS
FOR
AMPLIFIED
BIOIMAGING
243
10.4.2
ENZYME-ACTIVATED
DNA
CIRCUITS
FOR
AMPLIFIED
BIOIMAGING
245
10.4.3
RNA-STIMULATED
DNA
CIRCUITS
FOR
AMPLIFIED
BIOIMAGING
246
10.4.4
OTHER
STRATEGIES
FOR
REGULATING
DNA
CIRCUITS
249
10.5
CONCLUSION
AND
PERSPECTIVES
251
ACKNOWLEDGMENTS
252
REFERENCES
252
11
DNA
NANOSCAFFOLDS
FOR
BIOMACROMOLECULES
ORGANIZATION
AND
BIOIMAGING
APPLICATIONS
259
YUANFANG
CHEN,
JIAYI
LI,
AND
YUHE
R.
YANG
11.1
INTRODUCTION
259
11.2
ASSEMBLY
OF
DNA-SCAFFOLDED
BIOMACROMOLECULES
259
11.3
APPLICATION
OF
DNA
NANOSCAFFOLD
FOR
REGULATION
OF
ENZYME
CASCADE
REACTION
261
11.3.1
DISTANCE
CONTROL
OF
ENZYME
CASCADE
261
11.3.2
ENZYME
COMPARTMENTALIZATION
263
11.3.3
DIRECTED
SUBSTRATE
CHANNELING
WITH
SWINGING
ARMS
264
11.3.4
SCAFFOLDED
ENZYME
CASCADE
IN
LIVING
CELLS
265
11.4
DNA
NANOSTRUCTURES
EMPOWERED
BIOIMAGING
TECHNOLOGIES
267
11.4.1
DNA
NANOSTRUCTURES
SCAFFOLDED
FLUOROPHORE
EXPANSION
267
11.4.2
DNA-PAINT-BASED
SUPER-RESOLUTION
FLUORESCENCE
IMAGING
269
11.4.3
DNA
NANOSTRUCTURES-AS
SIS
TED
CRYOGENIC
ELECTRON
MICROSCOPY
CHARACTERIZATION
269
11.5
SUMMARY
AND
OUTLOOK
270
REFERENCES
271
X
CONTENTS
PART
III
DNA
NANOTECHNOLOGY
FOR
REGULATION
OF
CELLULAR
FUNCTIONS
279
12
ADOPTING
NUCLEIC
ACID
NANOTECHNOLOGY
FOR
GENETIC
REGULATION
INVIVO
281
FRIEDRICH
C.
SIMMET
12.1
12.2
INTRODUCTION
281
TOEHOLD-MEDIATED
STRAND
DISPLACEMENT:
SWITCHING
NUCLEIC
ACIDS
WITH
NUCLEIC
ACIDS
282
12.3
12.3.1
12.3.2
12.3.3
12.3.4
12.3.5
12.3.6
12.4
TOEHOLD
RIBOREGULATORS
AND
RELATED
SYSTEMS
283
RIBOSWITCHES
283
TRANSLATIONAL
SWITCHING
WITH
TOEHOLD
SWITCHES
284
TOEHOLD
SWITCHING
IN
EUKARYOTES
285
TRANSCRIPTIONAL
SWITCHING
286
APPLICATIONS
AS
SENSORS
286
APPLICATIONS
IN
BIOCOMPUTING
287
APPLYING
NUCLEIC
ACID
NANOTECHNOLOGY
TO
CRISPR
AND
RNA
INTERFERENCE
288
12.4.1
12.4.2
12.4.3
12.4.4
12.4.5
12.5
CRISPR
TECHNIQUES
288
SWITCHABLE
GUIDE
RNAS
289
IMPLEMENTING
MORE
COMPLEX
PROGRAMS
IN
MAMMALIAN
CELLS
291
COMBINING
CRISPR
WITH
ORIGAMI
292
MICRORNAS
AND
RNA
INTERFERENCE
292
DELIVERY
OF
NUCLEIC
ACID
DEVICES,
IN
VIVO
PRODUCTION,
AND
CHALLENGES
FOR
IN
VIVO
OPERATION
293
12.5.1
12.5.2
12.5.3
12.6
DELIVERY
293
IN
VIVO
PRODUCTION
293
CHALLENGES
294
CONCLUSION
AND
OUTLOOK
294
ACKNOWLEDGMENTS
295
REFERENCES
295
13
CELL
MEMBRANE
FUNCTIONALIZATION
VIA
NUCLEIC
ACID
TOOLS
FOR
VISUALIZATION
AND
REGULATION
OF
CELLULAR
RECEPTORS
303
SHAN
CHEN,
JINGYING
LI,
AND
HUANGHAO
YANG
13.1
NUCLEIC
ACID-BASED
FUNCTIONALIZATION
STRATEGIES:
FROM
RECEPTOR
INFORMATION
TO
DNA
PROBES
303
13.2
13.3
13.4
UNCOVERING
MOLECULAR
INFORMATION
OF
CELLULAR
RECEPTORS
307
GOVERNING
CELLULAR
RECEPTORS-MEDIATED
SIGNAL
TRANSDUCTION
313
CONCLUSION
318
ACKNOWLEDGMENTS
318
REFERENCES
318
CONTENTS
|
XI
14
HARNESSING
DNA
NANOTECHNOLOGY
FOR
NONGENETIC
MANIPULATION
AND
FUNCTIONALIZATION
OF
CELL
SURFACE
RECEPTOR
325
HEXIN
NAN,
HONG-HUI
WANG,
AND
ZHOU
NIE
14.1
INTRODUCTION
325
14.2
PRINCIPLE
OF
DNA-ENABLED
MOLECULAR
ENGINEERING
FOR
RECEPTOR
REGULATION
329
14.2.1
RECOGNITION
MODULE
FOR
RECEPTOR
MANIPULATION
330
14.2.2
SPATIAL
SCAFFOLD
MODULE
FOR
RECEPTOR
ORGANIZATION
330
14.2.3
DYNAMIC
ASSEMBLY
MODULE
FOR
KINETIC
CONTROL
OF
RECEPTOR
331
14.3
DNA
NANODEVICES
FOR
PROGRAMMING
RECEPTOR
FUNCTION
332
14.3.1
BIVALENT
APTAMER
MIMICKING
NATURAL
LIGAND
TO
INDUCE
RECEPTOR
DIMERIZATION
332
14.3.2
DNA
NANODEVICES
TO
CUSTOMIZE
RECEPTOR RESPONSIVENESS
333
14.3.3
LIGHT-RESPONSIVE
DNA
NANODEVICES
FOR
SPATIOTEMPORAL
RECEPTOR
REGULATION
335
14.3.4
DNA
NANODEVICES
FOR
VISUALIZATION
OF
RECEPTOR
ACTIVATION
337
14.4
ELABORATE
AND
INTELLIGENT
DNA
NANODEVICES
REPROGRAMMING
RECEPTOR
FUNCTION
339
14.4.1
MECHANICAL
CONTROL
OVER
RECEPTOR-MEDIATED
CELLULAR
BEHAVIOR
339
14.4.2
PRECISE
CELL
TARGETING
FOR
SELECTIVE
RECEPTOR
MODULATION
341
14.4.3
SPATIAL
ORGANIZATION
OF
NANOSCALE
RECEPTOR
DISTRIBUTION
344
14.5
CONCLUSIONS
AND
PERSPECTIVES
347
ACKNOWLEDGMENTS
348
REFERENCES
348
15
DNA-BASED
CELL
SURFACE
ENGINEERING
FOR
PROGRAMMING
MULTIPLE
CELL-CELL
INTERACTIONS
355
MINGSHU
XIAO,
YUEYANG
SUN,
LI
LI,
AND
HAO
PEI
15.1
DNA
NANOTECHNOLOGY:
THE
TOOL
OF
CHOICE
FOR
PROGRAMMING
CELL-CELL
INTERACTIONS
355
15.2
MODIFYING
CELL
SURFACE
WITH
DNA
356
15.3
PROGRAMMING
CELL-CELL
INTERACTIONS
BY
DNA
NANOTECHNOLOGY
359
15.3.1
LIGAND-RECEPTOR
BINDING-BASED
CELL-CELL
INTERACTIONS
359
15.3.2
DNA
HYBRIDIZATION-BASED
CELL-CELL
INTERACTIONS
362
15.3.3
DNA
CIRCUIT-REGULATED
CELL-CELL
INTERACTIONS
364
15.4
CONCLUSION
366
ACKNOWLEDGMENTS
367
REFERENCES
367
XII
CONTENTS
16
DESIGNER
DNA
NANOSTRUCTURES
AND
THEIR
CELLULAR
UPTAKE
BEHAVIORS
375
JING
YE,
DONGLEI
YANG,
CHENZHI
SHI,
FEI
ZHOU,
AND
PENGFEI
WANG
16.1
16.2
16.2.1
16.2.2
16.2.3
16.2.4
16.3
16.3.1
16.3.2
16.3.3
16.3.4
16.3.5
16.4
16.4.1
16.4.2
16.4.3
INTRODUCTION
375
DNA
NANOTECHNOLOGY
376
THE
BEGINNING
OF
DNA
NANOTECHNOLOGY
376
DNA
ORIGAMI
377
SINGLE-STRANDED
DNA
TILES
378
DYNAMIC
DNA
STRUCTURES
379
PATHWAYS
OF
CELL
ENDOCYTOSIS
381
CLATHRIN-MEDIATED
ENDOCYTOSIS
381
CLATHRIN-INDEPENDENT
ENDOCYTOSIS
382
PHAGOCYTOSIS
384
MACROPINOCYTOSIS
384
CAVEOLIN-MEDIATED
ENDOCYTOSIS
385
ANALYSIS
OF
DNA
NANOSTRUCTURES
'
CELLULAR
UPTAKE
BEHAVIORS
386
EFFECT
OF
SIZE
AND
SHAPE
ON
CELLULAR
UPTAKE
386
EFFECT
OF
SURFACE
MODIFICATIONS
ON
CELLULAR
UPTAKE
389
EFFECT
OF
OTHER
ASPECTS
ON
CELLULAR
UPTAKE
392
REFERENCES
395
PART
IV
DNA
NANOTECHNOLOGY
FOR
CELL-TARGETED
MEDICAL
APPLICATIONS
401
17
TOWARD
PRODUCTION
OF
NUCLEIC
ACID
NANOSTRUCTURES
IN
LIFE
CELLS
AND
THEIR
BIOMEDICAL
APPLICATIONS
403
MENGXI
ZHENG,
VICTORIA
E.
PALUZZI,
CUIZHENG
ZHANG,
AND
CHENGDE
MAO
17.1
17.1.1
17.1.2
17.2
17.2.1
17.2.2
17.3
17.4
DNA
NANOSTRUCTURES
403
STRATEGIES
OF
DNA
NANOSTRUCTURES
CONSTRUCTION
403
PRODUCTION
OF
SSDNA
NANOSTRUCTURES
IN
LIVING
CELLS
404
RNA
NANOSTRUCTURES
406
STRATEGIES
OF
RNA
NANOSTRUCTURES
CONSTRUCTION
406
PRODUCTION
OF
SSRNA
NANOSTRUCTURES
IN
LIVING
CELLS
407
APPLICATIONS
409
CONCLUSION
412
REFERENCES
412
18
ENGINEERING
NUCLEIC
ACID
STRUCTURES
FOR
PROGRAMMABLE
INTRACELLULAR
BIOCOMPUTATION
415
NA
WU,
PENGYAN
HAO,
CHUNHAI
FAN,
AND
YONGXI
ZHAO
REFERENCES
432
CONTENTS
XIII
19
DNA
SUPRAMOLECULAR
HYDROGELS
FOR
BIOMEDICAL
APPLICATIONS
437
ZIWEI
SHI,
YUANCHEN
DONG,
AND
DONGSHENG
LIU
19.1
19.2
19.2.1
19.2.2
19.2.2.1
INTRODUCTION
437
CLASSIFICATION
AND
PREPARATION
OF
DNA
SUPRAMOLECULAR
HYDROGELS
438
PURE
DNA
SUPRAMOLECULAR
HYDROGELS
438
HYBRID
SUPRAMOLECULAR
DNA
HYDROGELS
440
HYBRID
SUPRAMOLECULAR
DNA
HYDROGELS
DOPED
WITH
ORGANIC
POLYMERS
440
19.2.2.2
HYBRID
SUPRAMOLECULAR
DNA
HYDROGELS
DOPED
WITH
INORGANIC
NANOMATERIALS
442
19.2.2.3
19.3
19.3.1
19.3.2
19.3.3
19.3.4
19.3.5
19.3.5.1
19.3.5.2
19.4
DNA-BASED
DOUBLE
NETWORK
HYDROGELS
443
BIOMEDICAL
APPLICATION
OF
DNA
SUPRAMOLECULAR
HYDROGELS
443
DNA
SUPRAMOLECULAR
HYDROGELS
FOR
BIO-SENSING
443
DNA
SUPRAMOLECULAR
HYDROGELS
FOR
DRUG
DELIVERY
446
DNA
SUPRAMOLECULAR
HYDROGELS
FOR
IMMUNOTHERAPY
449
DNA
SUPRAMOLECULAR
HYDROGELS
FOR
3D
CELL
CULTURE
451
DNA
SUPRAMOLECULAR
HYDROGELS
FOR
TISSUE
ENGINEERING
454
CONSTRUCTION
OF
ARTIFICIAL
TISSUES
IN
VITRO
454
TISSUE
ENGINEERING
456
CONCLUSIONS
AND
PERSPECTIVES
458
REFERENCES
459
20
ROLLING
CIRCLE
AMPLIFICATION-BASED
DNA
NANOTECHNOLOGY
FOR
CELL
RESEARCH
467
NACHUAN
SONG,
YIWEN
CHU,
XUN
YOU,
AND
DAYONG
YANG
20.1
20.2
20.2.1
20.2.2
20.2.3
20.3
20.4
20.5
INTRODUCTION
467
PRINCIPLE
AND
SYNTHETIC
METHODS
OF
RCA
468
PRINCIPLE
468
DNA
HYDROGEL
469
DNA
NANOPARTICLES
469
RCA-BASED
DNA
NANOTECHNOLOGY
FOR
CELL
SEPARATION
469
RCA-BASED
DNA
NANOTECHNOLOGY
FOR
NUCLEIC
ACID
DRUG
DELIVERY
475
CONCLUSION
484
ACKNOWLEDGMENT
485
REFERENCES
485
21
PRECISE
INTEGRATION
OF
THERAPEUTICS
IN
DNA-BASED
NANOMATERIALS
FOR
CANCER
TREATMENTS
489
YIMENG
LI,
LIJUAN
ZHU,
AND
CHUAN
ZHANG
21.1
21.1.1
DNA-BASED
NANOMATERIALS
IN
BIOMEDICINE
490
PROPERTIES
OF
DNA-BASED
NANOMATERIALS
491
XIV
CONTENTS
INDEX
515
21.1.2
21.1.2.1
21.1.2.2
21.1.2.3
21.1.2.4
21.1.3
ARCHITECTURES
OF
DNA-BASED
NANOMATERIALS
492
DNA
POLYHEDRA
492
SPHERICAL
NUCLEIC
ACID
(SNA)
493
DNA
ORIGAMI
494
DNA
HYDROGEL
494
INTERACTIONS
BETWEEN
DNA-BASED
DRUG
DELIVERY
SYSTEMS
(DDSS)
AND
CELLS
495
21.1.3.1
21.1.3.2
21.2
21.2.1
21.2.2
21.2.2.1
ENDOCYTOSIS
OF
DNA-BASED
ARCHITECTURES
495
FATE
OF
DNA-BASED
ARCHITECTURES
IN
CELLS
498
STRATEGIES
ON
CONSTRUCTING
DNA-BASED
DDSS
498
DNA-BASED
DDSS
ENGINEERED
THROUGH
NON-COVALENT
INTERACTIONS
499
DNA-BASED
DDSS
ENGINEERED
THROUGH
COVALENT
INTERACTIONS
502
INTEGRATION
OF
THERAPEUTIC
NUCLEOSIDE
ANALOGS
(NAS)
INTO
NUCLEIC
ACID
STRANDS
502
21.2.2.2
21.2.2.3
GRAFTING
THE
CHEMOTHERAPEUTICS
ON
DNA
BACKBONE
504
DIRECTLY
CONJUGATING
THERAPEUTIC
AGENTS
ON
TERMINUS
OF
DNA
STRANDS
504
21.3
PRECISE
INTEGRATION
OF
THERAPEUTICS
INTO
DNA-BASED
DDSS
TO
ACHIEVE
SYNERGISTIC
CANCER
TREATMENT
507
21.3.1
21.3.2
CHEMOGENES
507
CHEMOGENE-BASED
DNA
NANOMATERIALS
508
REFERENCES
511 |
| adam_txt | |
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| author2 | Nie, Zhou |
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| author_GND | (DE-588)132732525X |
| author_facet | Nie, Zhou |
| building | Verbundindex |
| bvnumber | BV049631930 |
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| ctrlnum | (OCoLC)1437847469 (DE-599)DNB1305294459 |
| discipline | Biologie |
| discipline_str_mv | Biologie |
| format | Book |
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV049631930 |
| illustrated | Illustrated |
| index_date | 2024-07-03T23:38:28Z |
| indexdate | 2024-09-20T04:29:42Z |
| institution | BVB |
| institution_GND | (DE-588)16179388-5 |
| isbn | 9783527351732 3527351736 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-034975743 |
| oclc_num | 1437847469 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-19 DE-BY-UBM |
| owner_facet | DE-355 DE-BY-UBR DE-19 DE-BY-UBM |
| physical | xvi, 528 Seiten Illustrationen, Diagramme 24.4 cm x 17 cm, 1182 g |
| publishDate | 2024 |
| publishDateSearch | 2024 |
| publishDateSort | 2024 |
| publisher | Wiley-VCH |
| record_format | marc |
| spelling | DNA nanotechnology for cell research from bioanalysis to biomedicine edited by Zhou Nie Weinheim, Germany Wiley-VCH [2024] xvi, 528 Seiten Illustrationen, Diagramme 24.4 cm x 17 cm, 1182 g txt rdacontent n rdamedia nc rdacarrier Nanotechnologie (DE-588)4327470-5 gnd rswk-swf Cytologie (DE-588)4070177-3 gnd rswk-swf Nanobiotechnologie (DE-588)7657744-2 gnd rswk-swf DNS (DE-588)4070512-2 gnd rswk-swf Biomolecules (DNA, RNA, Peptides, etc.) Biomoleküle (DNA, RNA, Peptide) Biotechnologie i. d. Biowissenschaften Biotechnology Biowissenschaften Chemie Chemistry Life Sciences Nanobiotechnologie Nanobiotechnology Nanotechnologie Nanotechnology CHB1: Biomoleküle (DNA, RNA, Peptide) LS35: Biotechnologie i. d. Biowissenschaften NT50: Nanobiotechnologie Biotechnologie DNA DNS (DE-588)4143413-4 Aufsatzsammlung gnd-content DNS (DE-588)4070512-2 s Nanotechnologie (DE-588)4327470-5 s DE-604 Nanobiotechnologie (DE-588)7657744-2 s Cytologie (DE-588)4070177-3 s Nie, Zhou (DE-588)132732525X edt Wiley-VCH (DE-588)16179388-5 pbl Erscheint auch als Online-Ausgabe, PDF 978-3-527-84079-3 Erscheint auch als Online-Ausgabe, EPUB 978-3-527-84080-9 Erscheint auch als Online-Ausgabe 978-3-527-84081-6 X:MVB http://www.wiley-vch.de/publish/dt/books/ISBN978-3-527-35173-2/ DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=034975743&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p vlb 20231007 DE-101 https://d-nb.info/provenance/plan#vlb |
| spellingShingle | DNA nanotechnology for cell research from bioanalysis to biomedicine Nanotechnologie (DE-588)4327470-5 gnd Cytologie (DE-588)4070177-3 gnd Nanobiotechnologie (DE-588)7657744-2 gnd DNS (DE-588)4070512-2 gnd |
| subject_GND | (DE-588)4327470-5 (DE-588)4070177-3 (DE-588)7657744-2 (DE-588)4070512-2 (DE-588)4143413-4 |
| title | DNA nanotechnology for cell research from bioanalysis to biomedicine |
| title_auth | DNA nanotechnology for cell research from bioanalysis to biomedicine |
| title_exact_search | DNA nanotechnology for cell research from bioanalysis to biomedicine |
| title_exact_search_txtP | DNA nanotechnology for cell research from bioanalysis to biomedicine |
| title_full | DNA nanotechnology for cell research from bioanalysis to biomedicine edited by Zhou Nie |
| title_fullStr | DNA nanotechnology for cell research from bioanalysis to biomedicine edited by Zhou Nie |
| title_full_unstemmed | DNA nanotechnology for cell research from bioanalysis to biomedicine edited by Zhou Nie |
| title_short | DNA nanotechnology for cell research |
| title_sort | dna nanotechnology for cell research from bioanalysis to biomedicine |
| title_sub | from bioanalysis to biomedicine |
| topic | Nanotechnologie (DE-588)4327470-5 gnd Cytologie (DE-588)4070177-3 gnd Nanobiotechnologie (DE-588)7657744-2 gnd DNS (DE-588)4070512-2 gnd |
| topic_facet | Nanotechnologie Cytologie Nanobiotechnologie DNS Aufsatzsammlung |
| url | http://www.wiley-vch.de/publish/dt/books/ISBN978-3-527-35173-2/ http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=034975743&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT niezhou dnananotechnologyforcellresearchfrombioanalysistobiomedicine AT wileyvch dnananotechnologyforcellresearchfrombioanalysistobiomedicine |