The systemic effects of advanced cancer: a textbook on cancer-associated cachexia
Gespeichert in:
Weitere Verfasser: | |
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Format: | Buch |
Sprache: | English |
Veröffentlicht: |
Cham
Springer
[2022]
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Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis Klappentext |
Beschreibung: | vi, 203 Seiten Illustrationen |
ISBN: | 9783031072727 |
Internformat
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Datensatz im Suchindex
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adam_text | A Systemic View of Metastatic Disease: Inter-Organ Crosstalk and Therapeutic Implications............................................ 1 Swarnali Acharyya Part I Systemic Regulation in Metastatic Disease Systemic Regulation of Metastatic Disease by Extracellular Vesicles and Particles.................................................... Gang Wang, Candia Μ. Kenific, Grace Lieberman, Haiying Zhang, and David Lyden Bone Metastases: Systemic Regulation and Impact on Host........... Sukanya Suresh and Theresa A. Guise Targeting Metastatic Disease: Challenges and New Opportunities........................................................................ Haitian Hu, Zeping Hu, and Hanqiu Zheng Part II 41 51 Cachexia: A Debilitating Systemic Effect of Cancer Signaling Pathways That Promote Muscle Catabolism in Cachexia............................................................................................. J. E. Gilda and S. Cohen The Role of Interleukin-6/GP130 Cytokines in Cancer Cachexia... Daenique H. A. Jengelley and Teresa A. Zimmers NF-kB Signaling in the Macroenvironment of Cancer Cachexia.................................................................................... Benjamin R. Pryce and Denis C. Guttridge Part III 9 71 97 119 Therapy-Induced Muscle Wasting Therapy-Induced Toxicides Associated with the Onset of Cachexia................................................................................. Joshua R. Huot, Fabrizio Pin, and Andrea Bonetto 139 Bone-Muscle Crosstalk in Advanced Cancer and
Chemotherapy................................................................................ David L. Waning 155 V
vi Part IV Contents Preventing and Targeting Cachexia in Cancer New Developments in Targeting Cancer Cachexia............................ Janice Miller, Michael I. Ramage, and Richard J. E. Skipworth Exercise: A Critical Component of Cachexia Prevention and Therapy in Cancer............................................................................ Emidio E. Pistilli, Hannah E. Wilson, and David A. Stanton 171 193
Swarnali Acharyya Editor The Systemic Effects of Advanced Cancer A Textbook on Cancer-Associated Cachexia This textbook discusses the systemic consequences of cancer, covering a range of topics from tumor-promoting systemic effects to the development of cachexia, as summarized in the introductory chapter 1. Part I of this textbook focuses on tumor-promoting systemic effects and begins with a chapter on how tumor-derived extracellular vesicles and particles lay the foundation for future metastases (Chapter 2). Chapter 3 discusses how metastatic cells that have colonized the bone impact the local bone microenvironment, neighboring muscles, and host physiology. Chapter 4 summarizes the available strategies for targeting metastatic cancer and emphasizes the need to incorporate a systemic view of the disease. Following this overview of the systemic effects of cancer progression, Part II of the textbook discusses cancer-induced cachexia, a debilitating systemic effect of advanced cancer. Chapters 5-7 examine the key signaling pathways (interleukin-6/GP130, NF-кВ, and muscle proteolysis) that drive the development of cancer cachexia. Chapters 8 and 9 in Part III of this textbook explore how toxicities from anti-cancer therapy are associated with the onset of cachexia in cancer patients, and provide insight into potential approaches to simultaneously target both cancer and cachexia. Chapters 10 and 11 (Part IV) conclude this textbook by outlining promising approaches for the diagnosis and treatment of cachexia as well as strategies to prevent the development of cachexia through
exercise. An understanding of the systemic effects of cancer is essential for the design of effective anti-cancer and anti-cachexia treatment strategies. As such, this textbook provides key information for both students and scientists engaged in cancer research and oncology.
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adam_txt |
A Systemic View of Metastatic Disease: Inter-Organ Crosstalk and Therapeutic Implications. 1 Swarnali Acharyya Part I Systemic Regulation in Metastatic Disease Systemic Regulation of Metastatic Disease by Extracellular Vesicles and Particles. Gang Wang, Candia Μ. Kenific, Grace Lieberman, Haiying Zhang, and David Lyden Bone Metastases: Systemic Regulation and Impact on Host. Sukanya Suresh and Theresa A. Guise Targeting Metastatic Disease: Challenges and New Opportunities. Haitian Hu, Zeping Hu, and Hanqiu Zheng Part II 41 51 Cachexia: A Debilitating Systemic Effect of Cancer Signaling Pathways That Promote Muscle Catabolism in Cachexia. J. E. Gilda and S. Cohen The Role of Interleukin-6/GP130 Cytokines in Cancer Cachexia. Daenique H. A. Jengelley and Teresa A. Zimmers NF-kB Signaling in the Macroenvironment of Cancer Cachexia. Benjamin R. Pryce and Denis C. Guttridge Part III 9 71 97 119 Therapy-Induced Muscle Wasting Therapy-Induced Toxicides Associated with the Onset of Cachexia. Joshua R. Huot, Fabrizio Pin, and Andrea Bonetto 139 Bone-Muscle Crosstalk in Advanced Cancer and
Chemotherapy. David L. Waning 155 V
vi Part IV Contents Preventing and Targeting Cachexia in Cancer New Developments in Targeting Cancer Cachexia. Janice Miller, Michael I. Ramage, and Richard J. E. Skipworth Exercise: A Critical Component of Cachexia Prevention and Therapy in Cancer. Emidio E. Pistilli, Hannah E. Wilson, and David A. Stanton 171 193
Swarnali Acharyya Editor The Systemic Effects of Advanced Cancer A Textbook on Cancer-Associated Cachexia This textbook discusses the systemic consequences of cancer, covering a range of topics from tumor-promoting systemic effects to the development of cachexia, as summarized in the introductory chapter 1. Part I of this textbook focuses on tumor-promoting systemic effects and begins with a chapter on how tumor-derived extracellular vesicles and particles lay the foundation for future metastases (Chapter 2). Chapter 3 discusses how metastatic cells that have colonized the bone impact the local bone microenvironment, neighboring muscles, and host physiology. Chapter 4 summarizes the available strategies for targeting metastatic cancer and emphasizes the need to incorporate a systemic view of the disease. Following this overview of the systemic effects of cancer progression, Part II of the textbook discusses cancer-induced cachexia, a debilitating systemic effect of advanced cancer. Chapters 5-7 examine the key signaling pathways (interleukin-6/GP130, NF-кВ, and muscle proteolysis) that drive the development of cancer cachexia. Chapters 8 and 9 in Part III of this textbook explore how toxicities from anti-cancer therapy are associated with the onset of cachexia in cancer patients, and provide insight into potential approaches to simultaneously target both cancer and cachexia. Chapters 10 and 11 (Part IV) conclude this textbook by outlining promising approaches for the diagnosis and treatment of cachexia as well as strategies to prevent the development of cachexia through
exercise. An understanding of the systemic effects of cancer is essential for the design of effective anti-cancer and anti-cachexia treatment strategies. As such, this textbook provides key information for both students and scientists engaged in cancer research and oncology. |
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dewey-ones | 571 - Physiology & related subjects 616 - Diseases |
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dewey-search | 571.978 616.994 |
dewey-sort | 3571.978 |
dewey-tens | 570 - Biology 610 - Medicine and health |
discipline | Biologie Medizin |
discipline_str_mv | Biologie Medizin |
format | Book |
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spelling | The systemic effects of advanced cancer a textbook on cancer-associated cachexia Swarnali Acharyya, editor Cham Springer [2022] vi, 203 Seiten Illustrationen txt rdacontent n rdamedia nc rdacarrier Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Kachexie (DE-588)4234273-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Krebs Medizin (DE-588)4073781-0 s Kachexie (DE-588)4234273-9 s DE-604 Acharyya, Swarnali ca. 20./21. Jh. (DE-588)1314285912 edt Erscheint auch als Online-Ausgabe 978-3-031-09518-4 Digitalisierung UB Augsburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=034729095&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Augsburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=034729095&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
spellingShingle | The systemic effects of advanced cancer a textbook on cancer-associated cachexia Krebs Medizin (DE-588)4073781-0 gnd Kachexie (DE-588)4234273-9 gnd |
subject_GND | (DE-588)4073781-0 (DE-588)4234273-9 (DE-588)4143413-4 |
title | The systemic effects of advanced cancer a textbook on cancer-associated cachexia |
title_auth | The systemic effects of advanced cancer a textbook on cancer-associated cachexia |
title_exact_search | The systemic effects of advanced cancer a textbook on cancer-associated cachexia |
title_exact_search_txtP | The systemic effects of advanced cancer a textbook on cancer-associated cachexia |
title_full | The systemic effects of advanced cancer a textbook on cancer-associated cachexia Swarnali Acharyya, editor |
title_fullStr | The systemic effects of advanced cancer a textbook on cancer-associated cachexia Swarnali Acharyya, editor |
title_full_unstemmed | The systemic effects of advanced cancer a textbook on cancer-associated cachexia Swarnali Acharyya, editor |
title_short | The systemic effects of advanced cancer |
title_sort | the systemic effects of advanced cancer a textbook on cancer associated cachexia |
title_sub | a textbook on cancer-associated cachexia |
topic | Krebs Medizin (DE-588)4073781-0 gnd Kachexie (DE-588)4234273-9 gnd |
topic_facet | Krebs Medizin Kachexie Aufsatzsammlung |
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