Pathology of the Pancreas: a practical approach
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| Format: | Buch |
| Sprache: | English |
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Springer
[2021]
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| Ausgabe: | Second edition |
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| Beschreibung: | xv, 442 Seiten Illustrationen |
| ISBN: | 9783030498504 |
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Datensatz im Suchindex
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| adam_text | Contents Part I 1 General Principles Embryology, Anatomy, and Histology.............................................. 1.1 Introduction................................................................................ 1.2 Embryology................................................................................ 1.3 Anatomy...................................................................................... 1.4 Histology.................................................................................... References............................................................................................. Further Reading................................................................................... 2 Pancreatic Specimen Types................................................................ 2.1 Pancreatoduodenectomy Specimens....................................... 2.2 Distal Pancreatectomy Specimens............................................ 2.3 Total Pancreatectomy Specimens.............................................. 2.4 Duodenum-Preserving Pancreatic Resection Specimens........ 2.5 Complex Multivisceral En Bloc Resection Specimens.......... 2.6 Central Pancreatectomy Specimens.......................................... 2.7 Enucleation Specimens............................................................. 2.8 Specimens Following Frey, Beger, or Puestow Procedures... 2.9 Laparoscopic and Robot-Assisted Resection Specimens .... 2.10 Pancreas Allograft..................................................................... Further
Reading................................................................................... 3 Specimen Dissection and Sampling.................................................. Handling of Fresh Specimens.................................................. Specimen Fixation..................................................................... Macroscopic Examination of Pancreatoduodenectomy Specimens................................................................................... 3.4 Dissection of Distal Pancreatectomy Specimens.................... 3.5 Dissection of Total Pancreatectomy Specimens.................... 3.6 Dissection of Multivisceral En Bloc Resection Specimens....... 3.7 Dissection of Other Pancreatic Specimen Types.................... 3.8 Handling of Pancreatic Biopsies............................................. 3.9 Reporting Checklist of Macroscopic Findings...................... References............................................................................................. 3.1 3.2 3.3 4 The Pancreatic Multidisciplinary Team......................................... 4.1 4.2 Discussion of Postoperative Cases............................................. Discussion of Pretreatment Cases............................................. З З З 5 11 23 23 25 25 26 27 27 28 28 29 29 30 31 31 33 33 35 35 55 56 56 56 59 59 59 61 61 62 ix
Contents x 4.3 Other Roles and Responsibilities................................................ Reference............................................................................................... Part II 63 63 Exocrine Pancreas: Non-Cystic Common Minor Changes.................................................................. 5.1 Acinar Cell Nodules..................................................................... 5.2 Acinar Dilatation......................................................................... 5.3 Acinar to Ductal Metaplasia...................................................... 5.4 Duct Epithelial Metaplasia.......................................................... 5.5 Lobulocentric Atrophy................................................................. 5.6 Age-Related Alterations............................................................... 5.7 Fatty Replacement....................................................................... 5.8 Changes in Islets......................................................................... 5.9 Autolytic Change......................................................................... References.............................................................................................. 67 6 Hereditary Exocrine Disorders......................................................... 6.1 Cystic Fibrosis............................................................................ 6.2 Hereditary Hemochromatosis................................................... 6.3 Hereditary
Pancreatitis................................................................ 6.4 Inherited Pancreatic Cancer........................................................ 6.5 Familial Pancreatic Cancer........................................................ 6.6 Screening High-Risk Individuals............................................... References............................................................................................. 77 77 5 7 67 67 68 69 7(1 72 72 73 74 76 78 79 82 83 83 84 Inflammatory Disorders..................................................................... 87 7.1 Acute Pancreatitis...................................................................... 87 7.2 Chronic Pancreatitis.................................................................... 93 7.3 Other Inflammatory Diseases of the Pancreas.............................128 7.4 Pancreatitis in Children.............................................................. 132 7.5 Reporting Checklist.................................................................... 133 References............................................................................................. 134 8 Pancreatic Intraepithelial Neoplasia............................................... 137 8.1 WHO Classification.................................................................... 138 8.2 Classification and Microscopy.................................................. 138 8.3 Variants of PanIN....................................................................... 139 8.4
Associations............................................................................... 140 8.5 Lobulocentric Atrophy............................................................... 140 8.6 Differential Diagnosis............................................................... 140 References............................................................................................. լ 43 Further Reading................................................................................... I43 9 Ductal Adenocarcinoma....................................................................145 9.1 Definition and Terminology........................................................ I45 9.2 Epidemiology.............................................. 145 9.3 Etiology................................................................................... լ46 9.4 Clinical Features................................... լ 47
Contents xi 9.5 9.6 9.7 9.8 9.9 9.10 9.11 9.12 9.13 9.14 9.15 9.16 9.17 Macroscopy.................................................................................. 147 Microscopy .................................................................................. 150 Grading......................................................................................... 154 Morphological Patterns............................................................... 155 Immunohistochemistry............................................................... 159 Tumor Propagation........................................................................161 Staging........................................................................................... 164 Differential Diagnosis................................................................. 170 Treatment and Prognosis............................................................. 179 Histological Subtypes of Ductal Adenocarcinoma.................. 181 Carcinoma with Mixed Differentiation..................................... 191 Mixed Acinar-Ductal Carcinoma................................................ 191 Ductal Adenocarcinoma Following Neoadjuvant Treatment.............................................................................. 191 9.18 Diagnostic Molecular Pathology................................................ 197 9.19 Reporting Checklist..................................................................... 198 References................................................................................................ 199 10 Acinar Cell
Carcinoma......................................................................... 203 10.1 WHO Classification.................................................................... 203 10.2 Terminology.................................................................................203 10.3 Epidemiology.............................................................................. 203 10.4 Clinical Features........................................................................ 203 10.5 Macroscopy.................................................................................204 10.6 Microscopy................................................................................. 205 10.7 Histochemistry.............................................................................207 10.8 Immunohistochemistry..............................................................207 10.9 Molecular Pathology.................................................................. 209 10.10 Variants....................................................................................... 209 10.11 Differential Diagnosis................................................................210 10.12 Staging......................................................................................... 213 10.13 Prognosis and Management....................................................... 213 10.14 Reporting Checklist.................................................................... 213 References............................................................................................... 213 Further
Reading..................................................................................... 214 11 Non-Epithelial Neoplasia.................................................................... 215 11.1 Mesenchymal Neoplasms of the Pancreas................................ 216 11.2 Lymphoma...................................................................................221 References............................................................................................... 223 12 Secondary Neoplasia.............................................................................225 12.1 Definition..................................................................................... 225 12.2 Clinical Features........................................................................ 225 12.3 Macroscopy.................................................................................226 12.4 Microscopy.................................................................................227 12.5 Differential Diagnosis................................................................228 12.6 Synchronous Primary and Metastatic Cancer......................... 231 References............................................................................................... 234
Contents xii 13 Congenital and Developmental Abnormalities................................. 235 13.1 Pancreas Annulare....................................................................... 235 13.2 Pancreas Divisum......................................................................... 235 13.3 Pancreatobiliary Maljunction...................................................... 237 13.4 Pancreatic Heterotopia................................................................. 237 13.5 Ectopic Tissue in the Pancreas.................................................... 239 13.6 Benign Glandular Inclusions in Abdominal Lymph Nodes............................................................................... 241 References................................................................................................ 242 Part III Exocrine Pancreas: Cystic 14 Cystic Lesions: Classification and Sampling.................................. 245 14.1 Classification............................................................................... 245 14.2 Sampling of Cystic Lesions........................................................246 References............................................................................................... 248 15 Serous Cystic Neoplasia...................................................................... 249 15.1 WHO Classification.................................................................... 249 15.2 Terminology.................................................................................249 15.3
Epidemiology............................................................................... 249 15.4 Clinical Features........................................................................ 249 15.5 Classification............................................................................... 250 15.6 Macroscopy................................................................................. 250 15.7 Microscopy................................................................................. 252 15.8 Histochemistry.............................................................................255 15.9 Immunohistochemistry.............................................................. 255 15.10 Molecular Pathology.................................................................. 255 15.11 Rare Variants...............................................................................255 15.12 Differential Diagnosis................................................................ 258 15.13 Prognosis and Management....................................................... 259 15.14 Reporting Checklist.................................................................... 259 References............................................................................................... 259 Further Reading..................................................................................... 260 16 Mucinous Cystic Neoplasia................................................................ 261 16.1 WHO Classification.................................................................. 261 16.2
Terminology...............................................................................261 16.3 Epidemiology.............................................................................261 16.4 Clinical Features...................................................................... 261 16.5 Macroscopy................................................................................. 262 16.6 Microscopy ................................................................................ 264 16.7 Immunohistochemistry.............................................................. 268 16.8 Molecular Pathology.................................................................. 269 16.9 Variants........................................................... 269 16.10 Differential Diagnosis................................................................ 269 16.11 Staging.......................................... 27Q 16.12 Prognosis and Management....................................................... 270 16.13 Reporting Checklist.................................................................... 270 References....................................... շ7 q Further Reading...................................... 27]
Contents xiii 17 Intraductal Papillary Neoplasia........................................................ 273 17.1 WHO Classification.................................................................. 273 17.2 Intraductal Papillary Mucinous Neoplasm (IPMN)................273 17.3 Intraductal Oncocytic Papillary Neoplasm (IOPN).............. 286 17.4 Intraductal Tubulopapillary Neoplasm (ITPN)...................... 287 17.5 Staging....................................................................................... 289 17.6 Prognosis...................................................................................289 17.7 Management.............................................................................. 290 17.8 Reporting Checklist..................................................................291 References.............................................................................................. 292 Further Reading................................................................................... 293 18 Solid Pseudopapillary Neoplasia....................................................... 295 18.1 WHO Classification................................................................. 295 18.2 Terminology.............................................................................. 295 18.3 Epidemiology............................................................................ 295 18.4 Clinical Features...................................................................... 295 18.5
Macroscopy.............................................................................. 296 18.6 Microscopy.............................................................................. 297 18.7 Immunohistochemistry........................................................... 300 18.8 Molecular Pathology............................................................... 301 18.9 Variants.................................................................................... 301 18.10 Differential Diagnosis............................................................. 302 18.11 Staging....................................................................................... 303 18.12 Prognosis and Management..................................................... 303 18.13 Reporting Checklist.................................................................. 303 References.............................................................................................. 303 Further Reading.................................................................................... 304 19 Other Cystic Lesions........................................................................... 305 19.1 Acinar Cystic Transformation (Acinar Cell Cystadenoma)...................................................... 305 19.2 Mucinous Epithelium-Lined Cysts........................................ 308 19.3 Pancreatobiliary Epithelium-Lined Cysts.............................. 309 19.4 Squamous Epithelium-Lined Cysts........................................ 310 19.5 Other Cystic
Lesions............................................................... 315 References.............................................................................................. 316 Part IV 20 Endocrine Pancreas Endocrine Neoplasia........................................................................... 321 20.1 Terminology and Classification................................................ 321 20.2 Epidemiology............................................................................. 322 20.3 Clinical Features.......................................................................322 20.4 Macroscopy............................................................................... 326 20.5 Microscopy............................................................................... 327 20.6 Classification............................................................................. 334 20.7 Immunohistochemistry............................................................ 335 20.8 Staging....................................................................................... 337 20.9 Differential Diagnosis.............................................................. 339
Contents xiv 20.10 Mixed Neuroendocrine—Non-Neuroendocrine Neoplasm (MİNEN)......................................................... 344 20.11 Prognosis.................................................................................... 345 20.12 Inherited Syndromes................................................................... 346 20.13 Glucagon Cell Hyperplasia and Neoplasia.............................. 348 20.14 Insulinomatosis ........................................................................... 348 20.15 Endocrine Microadenoma and Endocrine Microadenomatosis......................................................... 350 20.16 Reporting Checklist..................................................................... 350 References................................................................................................ 353 Further Reading...................................................................................... 354 21 Endocrine Cell Hyperplasia................................................................ 355 21.1 Definition......................................................................................355 21.2 Beta-Cell Hyperplasia................................................................ 357 21.3 Alpha-Cell Hyperplasia.............................................................. 357 21.4 PP-Cell Hyperplasia..................................................................... 357 References................................................................................................ 358 Part V 22 Pathology of Pancreas
Transplantation ........................................... 361 René P. Michel 22.1 Introduction................................................................................. 361 22.2 Role of the Pathologist in Pancreas Transplantation............. 362 22.3 Pathologic Alterations Related to Operative Complications, and Examination and Findings in Failed Allografts.................................................................... 363 22.4 Core Biopsy Specimens in Pancreas Transplantation: Procedures and Technical Aspects................................. 365 22.5 Pancreas Allograft Rejection...................................................... 368 22.6 Infections in Pancreas Allografts................................................ 380 22.7 Recurrent Autoimmune Isletitis (Insulitis) and Diabetes Mellitus.....................................................382 22.8 Acute Islet Cell Toxicity from Calcineurin Inhibitors............ 382 22.9 Reporting Checklists................................................................... 382 References................................................................................................ 384 Part VI 23 Transplant Pathology Frozen Section The Role of Frozen Section................................................................ 389 23.1 Excluding a Metastasis...............................................................389 23.2 Pancreatic Ductal Adenocarcinoma Versus Chronic Pancreatitis.................................................................... 393 23.3 Assessing Margin
Status.............................................................398 References............................................................................................... 400
Contents XV Part VII 24 Cytology The Role of Cytology.......................................................................... 403 Μ. Priyanthi Kumarasinghe and Ian Yusoff 24.1 Tissue Acquisition...................................................................... 404 24.2 Sample Preparation.................................................................... 405 24.3 Microscopic Evaluation.............................................................. 407 24.4 Metastases................................................................................... 431 24.5 Molecular Testing inPancreatobiliary Cytology....................... 431 References............................................................................................... 431 Appendix: WHO Classification of Tumors of the Pancreas 2019.................................................................................... 433 Index................................................................................................................ 435
Fiona Campbell · Caroline S. Verbeke Pathology of the Pancreas A Practical Approach Second Edition This updated volume provides a practical guide to pancreatic pathology that covers recent changes in concepts and classifications. Potential pit falls and mimics in pancreatic pathology are highlighted and illustrated, and guidance is provided regarding how to recognise and avoid them. There is a new chapter on transplant pathology, and more than 200 new macroscopic and microscopic images have been added. Pathology of the Pancreas: A Practical Approach aims to enable readers to recognise the various pathological entities and provide the key informa tion in their pathology reports, which is necessary for the individual patient’s further management. The book provides the diagnostic patholo gist with a comprehensive, well-illustrated, and extensively cross-refer enced approach to pancreatic pathology.
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| adam_txt |
Contents Part I 1 General Principles Embryology, Anatomy, and Histology. 1.1 Introduction. 1.2 Embryology. 1.3 Anatomy. 1.4 Histology. References. Further Reading. 2 Pancreatic Specimen Types. 2.1 Pancreatoduodenectomy Specimens. 2.2 Distal Pancreatectomy Specimens. 2.3 Total Pancreatectomy Specimens. 2.4 Duodenum-Preserving Pancreatic Resection Specimens. 2.5 Complex Multivisceral En Bloc Resection Specimens. 2.6 Central Pancreatectomy Specimens. 2.7 Enucleation Specimens. 2.8 Specimens Following Frey, Beger, or Puestow Procedures. 2.9 Laparoscopic and Robot-Assisted Resection Specimens . 2.10 Pancreas Allograft. Further
Reading. 3 Specimen Dissection and Sampling. Handling of Fresh Specimens. Specimen Fixation. Macroscopic Examination of Pancreatoduodenectomy Specimens. 3.4 Dissection of Distal Pancreatectomy Specimens. 3.5 Dissection of Total Pancreatectomy Specimens. 3.6 Dissection of Multivisceral En Bloc Resection Specimens. 3.7 Dissection of Other Pancreatic Specimen Types. 3.8 Handling of Pancreatic Biopsies. 3.9 Reporting Checklist of Macroscopic Findings. References. 3.1 3.2 3.3 4 The Pancreatic Multidisciplinary Team. 4.1 4.2 Discussion of Postoperative Cases. Discussion of Pretreatment Cases. З З З 5 11 23 23 25 25 26 27 27 28 28 29 29 30 31 31 33 33 35 35 55 56 56 56 59 59 59 61 61 62 ix
Contents x 4.3 Other Roles and Responsibilities. Reference. Part II 63 63 Exocrine Pancreas: Non-Cystic Common Minor Changes. 5.1 Acinar Cell Nodules. 5.2 Acinar Dilatation. 5.3 Acinar to Ductal Metaplasia. 5.4 Duct Epithelial Metaplasia. 5.5 Lobulocentric Atrophy. 5.6 Age-Related Alterations. 5.7 Fatty Replacement. 5.8 Changes in Islets. 5.9 Autolytic Change. References. 67 6 Hereditary Exocrine Disorders. 6.1 Cystic Fibrosis. 6.2 Hereditary Hemochromatosis. 6.3 Hereditary
Pancreatitis. 6.4 Inherited Pancreatic Cancer. 6.5 Familial Pancreatic Cancer. 6.6 Screening High-Risk Individuals. References. 77 77 5 7 67 67 68 69 7(1 72 72 73 74 76 78 79 82 83 83 84 Inflammatory Disorders. 87 7.1 Acute Pancreatitis. 87 7.2 Chronic Pancreatitis. 93 7.3 Other Inflammatory Diseases of the Pancreas.128 7.4 Pancreatitis in Children. 132 7.5 Reporting Checklist. 133 References. 134 8 Pancreatic Intraepithelial Neoplasia. 137 8.1 WHO Classification. 138 8.2 Classification and Microscopy. 138 8.3 Variants of PanIN. 139 8.4
Associations. 140 8.5 Lobulocentric Atrophy. 140 8.6 Differential Diagnosis. 140 References. լ 43 Further Reading. I43 9 Ductal Adenocarcinoma.145 9.1 Definition and Terminology. I45 9.2 Epidemiology. 145 9.3 Etiology. " լ46 9.4 Clinical Features. լ 47
Contents xi 9.5 9.6 9.7 9.8 9.9 9.10 9.11 9.12 9.13 9.14 9.15 9.16 9.17 Macroscopy. 147 Microscopy . 150 Grading. 154 Morphological Patterns. 155 Immunohistochemistry. 159 Tumor Propagation.161 Staging. 164 Differential Diagnosis. 170 Treatment and Prognosis. 179 Histological Subtypes of Ductal Adenocarcinoma. 181 Carcinoma with Mixed Differentiation. 191 Mixed Acinar-Ductal Carcinoma. 191 Ductal Adenocarcinoma Following Neoadjuvant Treatment. 191 9.18 Diagnostic Molecular Pathology. 197 9.19 Reporting Checklist. 198 References. 199 10 Acinar Cell
Carcinoma. 203 10.1 WHO Classification. 203 10.2 Terminology.203 10.3 Epidemiology. 203 10.4 Clinical Features. 203 10.5 Macroscopy.204 10.6 Microscopy. 205 10.7 Histochemistry.207 10.8 Immunohistochemistry.207 10.9 Molecular Pathology. 209 10.10 Variants. 209 10.11 Differential Diagnosis.210 10.12 Staging. 213 10.13 Prognosis and Management. 213 10.14 Reporting Checklist. 213 References. 213 Further
Reading. 214 11 Non-Epithelial Neoplasia. 215 11.1 Mesenchymal Neoplasms of the Pancreas. 216 11.2 Lymphoma.221 References. 223 12 Secondary Neoplasia.225 12.1 Definition. 225 12.2 Clinical Features. 225 12.3 Macroscopy.226 12.4 Microscopy.227 12.5 Differential Diagnosis.228 12.6 Synchronous Primary and Metastatic Cancer. 231 References. 234
Contents xii 13 Congenital and Developmental Abnormalities. 235 13.1 Pancreas Annulare. 235 13.2 Pancreas Divisum. 235 13.3 Pancreatobiliary Maljunction. 237 13.4 Pancreatic Heterotopia. 237 13.5 Ectopic Tissue in the Pancreas. 239 13.6 Benign Glandular Inclusions in Abdominal Lymph Nodes. 241 References. 242 Part III Exocrine Pancreas: Cystic 14 Cystic Lesions: Classification and Sampling. 245 14.1 Classification. 245 14.2 Sampling of Cystic Lesions.246 References. 248 15 Serous Cystic Neoplasia. 249 15.1 WHO Classification. 249 15.2 Terminology.249 15.3
Epidemiology. 249 15.4 Clinical Features. 249 15.5 Classification. 250 15.6 Macroscopy. 250 15.7 Microscopy. 252 15.8 Histochemistry.255 15.9 Immunohistochemistry. 255 15.10 Molecular Pathology. 255 15.11 Rare Variants.255 15.12 Differential Diagnosis. 258 15.13 Prognosis and Management. 259 15.14 Reporting Checklist. 259 References. 259 Further Reading. 260 16 Mucinous Cystic Neoplasia. 261 16.1 WHO Classification. 261 16.2
Terminology.261 16.3 Epidemiology.261 16.4 Clinical Features. 261 16.5 Macroscopy. 262 16.6 Microscopy . 264 16.7 Immunohistochemistry. 268 16.8 Molecular Pathology. 269 16.9 Variants. 269 16.10 Differential Diagnosis. 269 16.11 Staging. 27Q 16.12 Prognosis and Management. 270 16.13 Reporting Checklist. 270 References. շ7 q Further Reading. 27]
Contents xiii 17 Intraductal Papillary Neoplasia. 273 17.1 WHO Classification. 273 17.2 Intraductal Papillary Mucinous Neoplasm (IPMN).273 17.3 Intraductal Oncocytic Papillary Neoplasm (IOPN). 286 17.4 Intraductal Tubulopapillary Neoplasm (ITPN). 287 17.5 Staging. 289 17.6 Prognosis.289 17.7 Management. 290 17.8 Reporting Checklist.291 References. 292 Further Reading. 293 18 Solid Pseudopapillary Neoplasia. 295 18.1 WHO Classification. 295 18.2 Terminology. 295 18.3 Epidemiology. 295 18.4 Clinical Features. 295 18.5
Macroscopy. 296 18.6 Microscopy. 297 18.7 Immunohistochemistry. 300 18.8 Molecular Pathology. 301 18.9 Variants. 301 18.10 Differential Diagnosis. 302 18.11 Staging. 303 18.12 Prognosis and Management. 303 18.13 Reporting Checklist. 303 References. 303 Further Reading. 304 19 Other Cystic Lesions. 305 19.1 Acinar Cystic Transformation (Acinar Cell Cystadenoma). 305 19.2 Mucinous Epithelium-Lined Cysts. 308 19.3 Pancreatobiliary Epithelium-Lined Cysts. 309 19.4 Squamous Epithelium-Lined Cysts. 310 19.5 Other Cystic
Lesions. 315 References. 316 Part IV 20 Endocrine Pancreas Endocrine Neoplasia. 321 20.1 Terminology and Classification. 321 20.2 Epidemiology. 322 20.3 Clinical Features.322 20.4 Macroscopy. 326 20.5 Microscopy. 327 20.6 Classification. 334 20.7 Immunohistochemistry. 335 20.8 Staging. 337 20.9 Differential Diagnosis. 339
Contents xiv 20.10 Mixed Neuroendocrine—Non-Neuroendocrine Neoplasm (MİNEN). 344 20.11 Prognosis. 345 20.12 Inherited Syndromes. 346 20.13 Glucagon Cell Hyperplasia and Neoplasia. 348 20.14 Insulinomatosis . 348 20.15 Endocrine Microadenoma and Endocrine Microadenomatosis. 350 20.16 Reporting Checklist. 350 References. 353 Further Reading. 354 21 Endocrine Cell Hyperplasia. 355 21.1 Definition.355 21.2 Beta-Cell Hyperplasia. 357 21.3 Alpha-Cell Hyperplasia. 357 21.4 PP-Cell Hyperplasia. 357 References. 358 Part V 22 Pathology of Pancreas
Transplantation . 361 René P. Michel 22.1 Introduction. 361 22.2 Role of the Pathologist in Pancreas Transplantation. 362 22.3 Pathologic Alterations Related to Operative Complications, and Examination and Findings in Failed Allografts. 363 22.4 Core Biopsy Specimens in Pancreas Transplantation: Procedures and Technical Aspects. 365 22.5 Pancreas Allograft Rejection. 368 22.6 Infections in Pancreas Allografts. 380 22.7 Recurrent Autoimmune Isletitis (Insulitis) and Diabetes Mellitus.382 22.8 Acute Islet Cell Toxicity from Calcineurin Inhibitors. 382 22.9 Reporting Checklists. 382 References. 384 Part VI 23 Transplant Pathology Frozen Section The Role of Frozen Section. 389 23.1 Excluding a Metastasis.389 23.2 Pancreatic Ductal Adenocarcinoma Versus Chronic Pancreatitis. 393 23.3 Assessing Margin
Status.398 References. 400
Contents XV Part VII 24 Cytology The Role of Cytology. 403 Μ. Priyanthi Kumarasinghe and Ian Yusoff 24.1 Tissue Acquisition. 404 24.2 Sample Preparation. 405 24.3 Microscopic Evaluation. 407 24.4 Metastases. 431 24.5 Molecular Testing inPancreatobiliary Cytology. 431 References. 431 Appendix: WHO Classification of Tumors of the Pancreas 2019. 433 Index. 435
Fiona Campbell · Caroline S. Verbeke Pathology of the Pancreas A Practical Approach Second Edition This updated volume provides a practical guide to pancreatic pathology that covers recent changes in concepts and classifications. Potential pit falls and mimics in pancreatic pathology are highlighted and illustrated, and guidance is provided regarding how to recognise and avoid them. There is a new chapter on transplant pathology, and more than 200 new macroscopic and microscopic images have been added. Pathology of the Pancreas: A Practical Approach aims to enable readers to recognise the various pathological entities and provide the key informa tion in their pathology reports, which is necessary for the individual patient’s further management. The book provides the diagnostic patholo gist with a comprehensive, well-illustrated, and extensively cross-refer enced approach to pancreatic pathology. |
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| author | Campbell, Fiona Verbeke, Caroline Sophie |
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| edition | Second edition |
| format | Book |
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| id | DE-604.BV048466428 |
| illustrated | Illustrated |
| index_date | 2024-07-03T20:35:27Z |
| indexdate | 2024-07-10T09:38:55Z |
| institution | BVB |
| isbn | 9783030498504 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-033844324 |
| oclc_num | 1298707726 |
| open_access_boolean | |
| owner | DE-19 DE-BY-UBM DE-384 |
| owner_facet | DE-19 DE-BY-UBM DE-384 |
| physical | xv, 442 Seiten Illustrationen |
| publishDate | 2021 |
| publishDateSearch | 2021 |
| publishDateSort | 2021 |
| publisher | Springer |
| record_format | marc |
| spelling | Campbell, Fiona Verfasser aut Pathology of the Pancreas a practical approach Fiona Campbell, Caroline S. Verbeke Second edition Cham Springer [2021] xv, 442 Seiten Illustrationen txt rdacontent n rdamedia nc rdacarrier Pathology Imaging / Radiology Radiology Bauchspeicheldrüsenkrankheit (DE-588)4004727-1 gnd rswk-swf Bauchspeicheldrüsenkrankheit (DE-588)4004727-1 s DE-604 Verbeke, Caroline Sophie (DE-588)107720101X aut Erscheint auch als Online-Ausgabe 978-3-030-49848-1 Digitalisierung UB Augsburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=033844324&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Augsburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=033844324&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Campbell, Fiona Verbeke, Caroline Sophie Pathology of the Pancreas a practical approach Pathology Imaging / Radiology Radiology Bauchspeicheldrüsenkrankheit (DE-588)4004727-1 gnd |
| subject_GND | (DE-588)4004727-1 |
| title | Pathology of the Pancreas a practical approach |
| title_auth | Pathology of the Pancreas a practical approach |
| title_exact_search | Pathology of the Pancreas a practical approach |
| title_exact_search_txtP | Pathology of the Pancreas a practical approach |
| title_full | Pathology of the Pancreas a practical approach Fiona Campbell, Caroline S. Verbeke |
| title_fullStr | Pathology of the Pancreas a practical approach Fiona Campbell, Caroline S. Verbeke |
| title_full_unstemmed | Pathology of the Pancreas a practical approach Fiona Campbell, Caroline S. Verbeke |
| title_short | Pathology of the Pancreas |
| title_sort | pathology of the pancreas a practical approach |
| title_sub | a practical approach |
| topic | Pathology Imaging / Radiology Radiology Bauchspeicheldrüsenkrankheit (DE-588)4004727-1 gnd |
| topic_facet | Pathology Imaging / Radiology Radiology Bauchspeicheldrüsenkrankheit |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=033844324&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=033844324&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT campbellfiona pathologyofthepancreasapracticalapproach AT verbekecarolinesophie pathologyofthepancreasapracticalapproach |