Update on the management of non-obstructive azoospermia: current evidence and unmet needs
Azoospermia, defined as the absence of sperm in the ejaculate after examination of the centrifuged specimens, affects about 1% of the male population and 10–15% of infertile men. In about two-thirds of cases, this is caused by severe spermatogenic dysfunction, and it is commonly termed "nonobst...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Basel
MDPI - Multidisciplinary Digital Publishing Institute
[2022]
|
| Schlagworte: | |
| Online-Zugang: | kostenfrei kostenfrei |
| Zusammenfassung: | Azoospermia, defined as the absence of sperm in the ejaculate after examination of the centrifuged specimens, affects about 1% of the male population and 10–15% of infertile men. In about two-thirds of cases, this is caused by severe spermatogenic dysfunction, and it is commonly termed "nonobstructive azoospermia" (NOA) to differentiate it from the less severe form of azoospermia caused by the obstruction of the seminal tract (obstructive azoospermia—OA), the latter affecting the remaining one-third of cases. Managing patients with NOA is challenging due to the severity of spermatogenic dysfunction and the lack of medical treatments, with surgical retrieval of testicular sperm being the only way of enabling some of these patients to father their own biological children. In-depth clinical knowledge is key for supporting clinical reasoning and decision making when counselling patients with NOA, and surgical skill is required to maximize the outcome of surgical procedures that aim to retrieve testicular sperm. The present book is a collection of scientific papers published in a Special Issue of the Journal of Clinical Medicine, authored by some of the most influential researchers in the field. The Special Issue, and thus also this book, were conceived to provide early career reproductive urologists and endocrinologists with an update of the scientific evidence in the field, together with surgical tips. |
| Beschreibung: | Titelrückseite: This is a reprint of articles from the Special Issue published online in the open access journal Journal of Clinical Medicine (ISSN 2077-0383) (available at: https://www.mdpi.com/journal/jcm/special_issues/NOA_Management). |
| Beschreibung: | 1 Online-Ressource (157 Seiten) |
| ISBN: | 9783036534343 |
| DOI: | 10.3390/books978-3-0365-3434-3 |
Internformat
MARC
| LEADER | 00000nam a22000001c 4500 | ||
|---|---|---|---|
| 001 | BV048421785 | ||
| 003 | DE-604 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 220825s2022 xx o|||| 00||| eng d | ||
| 020 | |a 9783036534343 |9 978-3-0365-3434-3 | ||
| 024 | 7 | |a 10.3390/books978-3-0365-3434-3 |2 doi | |
| 035 | |a (OCoLC)1344239027 | ||
| 035 | |a (DE-599)HEB497451832 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-12 |a DE-210 |a DE-521 |a DE-1102 |a DE-1046 |a DE-1028 |a DE-1050 |a DE-573 |a DE-M347 |a DE-92 |a DE-1051 |a DE-898 |a DE-859 |a DE-860 |a DE-1049 |a DE-861 |a DE-863 |a DE-862 |a DE-Re13 |a DE-Y3 |a DE-255 |a DE-Y7 |a DE-Y2 |a DE-70 |a DE-2174 |a DE-127 |a DE-22 |a DE-155 |a DE-91 |a DE-384 |a DE-473 |a DE-19 |a DE-355 |a DE-703 |a DE-20 |a DE-706 |a DE-824 |a DE-29 |a DE-739 | ||
| 084 | |a YK 9694 |0 (DE-625)153808:13003 |2 rvk | ||
| 084 | |a YM 2567 |0 (DE-625)153826:12974 |2 rvk | ||
| 245 | 1 | 0 | |a Update on the management of non-obstructive azoospermia |b current evidence and unmet needs |c editors Giovanni M. Colpi, Ettore Caroppo |
| 264 | 1 | |a Basel |b MDPI - Multidisciplinary Digital Publishing Institute |c [2022] | |
| 264 | 2 | |a The Hague |b OAPEN FOUNDATION | |
| 264 | 4 | |c © 2022 | |
| 300 | |a 1 Online-Ressource (157 Seiten) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 500 | |a Titelrückseite: This is a reprint of articles from the Special Issue published online in the open access journal Journal of Clinical Medicine (ISSN 2077-0383) (available at: https://www.mdpi.com/journal/jcm/special_issues/NOA_Management). | ||
| 520 | 3 | |a Azoospermia, defined as the absence of sperm in the ejaculate after examination of the centrifuged specimens, affects about 1% of the male population and 10–15% of infertile men. In about two-thirds of cases, this is caused by severe spermatogenic dysfunction, and it is commonly termed "nonobstructive azoospermia" (NOA) to differentiate it from the less severe form of azoospermia caused by the obstruction of the seminal tract (obstructive azoospermia—OA), the latter affecting the remaining one-third of cases. Managing patients with NOA is challenging due to the severity of spermatogenic dysfunction and the lack of medical treatments, with surgical retrieval of testicular sperm being the only way of enabling some of these patients to father their own biological children. In-depth clinical knowledge is key for supporting clinical reasoning and decision making when counselling patients with NOA, and surgical skill is required to maximize the outcome of surgical procedures that aim to retrieve testicular sperm. The present book is a collection of scientific papers published in a Special Issue of the Journal of Clinical Medicine, authored by some of the most influential researchers in the field. The Special Issue, and thus also this book, were conceived to provide early career reproductive urologists and endocrinologists with an update of the scientific evidence in the field, together with surgical tips. | |
| 650 | 0 | 7 | |a Azoospermie |0 (DE-588)4143820-6 |2 gnd |9 rswk-swf |
| 653 | |a nonobstructive azoospermia | ||
| 653 | |a micro-TESE | ||
| 653 | |a FSH treatment | ||
| 653 | |a hormonal treatment | ||
| 653 | |a testosterone level | ||
| 653 | |a microdissection testicular sperm extraction | ||
| 653 | |a non-obstructive azoospermia | ||
| 653 | |a management | ||
| 653 | |a infertility | ||
| 653 | |a intracytoplasmic sperm injection | ||
| 653 | |a testicular azoospermia | ||
| 653 | |a sperm selection | ||
| 653 | |a sperm | ||
| 653 | |a cryopreservation | ||
| 653 | |a in vitro maturation | ||
| 653 | |a azoospermia | ||
| 653 | |a diagnosis | ||
| 653 | |a male infertility | ||
| 653 | |a spermatogenic failure | ||
| 653 | |a testis biopsy | ||
| 653 | |a sperm retrieval | ||
| 653 | |a genetic testing | ||
| 653 | |a endocrine evaluation | ||
| 653 | |a review | ||
| 653 | |a hypogonadism | ||
| 653 | |a Sertoli cell-only syndrome | ||
| 653 | |a testicular spermatozoa | ||
| 653 | |a processing | ||
| 653 | |a microfluidics | ||
| 653 | |a new technologies | ||
| 653 | |a genetics | ||
| 653 | |a exome | ||
| 653 | |a WES | ||
| 653 | |a Y chromosome | ||
| 653 | |a cancer | ||
| 653 | |a NOA | ||
| 653 | |a genes | ||
| 653 | |a general health | ||
| 653 | |a ICSI | ||
| 653 | |a offspring health | ||
| 653 | |a microTESE | ||
| 653 | |a prediction model | ||
| 655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
| 689 | 0 | 0 | |a Azoospermie |0 (DE-588)4143820-6 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Colpi, Giovanni M. |0 (DE-588)1266351922 |4 edt | |
| 700 | 1 | |a Caroppo, Ettore |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe, Hardcover |z 978-3-0365-3433-6 |
| 856 | 4 | 0 | |u https://directory.doabooks.org/handle/20.500.12854/81136 |x Verlag |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u https://doi.org/10.3390/books978-3-0365-3434-3 |x Verlag |z kostenfrei |3 Volltext |
| 912 | |a ZDB-94-OAB | ||
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-033800072 | |
Datensatz im Suchindex
| _version_ | 1822082593691009024 |
|---|---|
| adam_text | |
| adam_txt | |
| any_adam_object | |
| any_adam_object_boolean | |
| author2 | Colpi, Giovanni M. Caroppo, Ettore |
| author2_role | edt edt |
| author2_variant | g m c gm gmc e c ec |
| author_GND | (DE-588)1266351922 |
| author_facet | Colpi, Giovanni M. Caroppo, Ettore |
| building | Verbundindex |
| bvnumber | BV048421785 |
| classification_rvk | YK 9694 YM 2567 |
| collection | ZDB-94-OAB |
| ctrlnum | (OCoLC)1344239027 (DE-599)HEB497451832 |
| discipline | Medizin |
| discipline_str_mv | Medizin |
| doi_str_mv | 10.3390/books978-3-0365-3434-3 |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>00000nam a22000001c 4500</leader><controlfield tag="001">BV048421785</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">220825s2022 xx o|||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9783036534343</subfield><subfield code="9">978-3-0365-3434-3</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.3390/books978-3-0365-3434-3</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1344239027</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)HEB497451832</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-12</subfield><subfield code="a">DE-210</subfield><subfield code="a">DE-521</subfield><subfield code="a">DE-1102</subfield><subfield code="a">DE-1046</subfield><subfield code="a">DE-1028</subfield><subfield code="a">DE-1050</subfield><subfield code="a">DE-573</subfield><subfield code="a">DE-M347</subfield><subfield code="a">DE-92</subfield><subfield code="a">DE-1051</subfield><subfield code="a">DE-898</subfield><subfield code="a">DE-859</subfield><subfield code="a">DE-860</subfield><subfield code="a">DE-1049</subfield><subfield code="a">DE-861</subfield><subfield code="a">DE-863</subfield><subfield code="a">DE-862</subfield><subfield code="a">DE-Re13</subfield><subfield code="a">DE-Y3</subfield><subfield code="a">DE-255</subfield><subfield code="a">DE-Y7</subfield><subfield code="a">DE-Y2</subfield><subfield code="a">DE-70</subfield><subfield code="a">DE-2174</subfield><subfield code="a">DE-127</subfield><subfield code="a">DE-22</subfield><subfield code="a">DE-155</subfield><subfield code="a">DE-91</subfield><subfield code="a">DE-384</subfield><subfield code="a">DE-473</subfield><subfield code="a">DE-19</subfield><subfield code="a">DE-355</subfield><subfield code="a">DE-703</subfield><subfield code="a">DE-20</subfield><subfield code="a">DE-706</subfield><subfield code="a">DE-824</subfield><subfield code="a">DE-29</subfield><subfield code="a">DE-739</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">YK 9694</subfield><subfield code="0">(DE-625)153808:13003</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">YM 2567</subfield><subfield code="0">(DE-625)153826:12974</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Update on the management of non-obstructive azoospermia</subfield><subfield code="b">current evidence and unmet needs</subfield><subfield code="c">editors Giovanni M. Colpi, Ettore Caroppo</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Basel</subfield><subfield code="b">MDPI - Multidisciplinary Digital Publishing Institute</subfield><subfield code="c">[2022]</subfield></datafield><datafield tag="264" ind1=" " ind2="2"><subfield code="a">The Hague</subfield><subfield code="b">OAPEN FOUNDATION</subfield></datafield><datafield tag="264" ind1=" " ind2="4"><subfield code="c">© 2022</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (157 Seiten)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Titelrückseite: This is a reprint of articles from the Special Issue published online in the open access journal Journal of Clinical Medicine (ISSN 2077-0383) (available at: https://www.mdpi.com/journal/jcm/special_issues/NOA_Management).</subfield></datafield><datafield tag="520" ind1="3" ind2=" "><subfield code="a">Azoospermia, defined as the absence of sperm in the ejaculate after examination of the centrifuged specimens, affects about 1% of the male population and 10–15% of infertile men. In about two-thirds of cases, this is caused by severe spermatogenic dysfunction, and it is commonly termed "nonobstructive azoospermia" (NOA) to differentiate it from the less severe form of azoospermia caused by the obstruction of the seminal tract (obstructive azoospermia—OA), the latter affecting the remaining one-third of cases. Managing patients with NOA is challenging due to the severity of spermatogenic dysfunction and the lack of medical treatments, with surgical retrieval of testicular sperm being the only way of enabling some of these patients to father their own biological children. In-depth clinical knowledge is key for supporting clinical reasoning and decision making when counselling patients with NOA, and surgical skill is required to maximize the outcome of surgical procedures that aim to retrieve testicular sperm. The present book is a collection of scientific papers published in a Special Issue of the Journal of Clinical Medicine, authored by some of the most influential researchers in the field. The Special Issue, and thus also this book, were conceived to provide early career reproductive urologists and endocrinologists with an update of the scientific evidence in the field, together with surgical tips.</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Azoospermie</subfield><subfield code="0">(DE-588)4143820-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">nonobstructive azoospermia</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">micro-TESE</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">FSH treatment</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">hormonal treatment</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">testosterone level</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">microdissection testicular sperm extraction</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">non-obstructive azoospermia</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">management</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">infertility</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">intracytoplasmic sperm injection</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">testicular azoospermia</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">sperm selection</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">sperm</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cryopreservation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">in vitro maturation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">azoospermia</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">diagnosis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">male infertility</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">spermatogenic failure</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">testis biopsy</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">sperm retrieval</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">genetic testing</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">endocrine evaluation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">review</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">hypogonadism</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Sertoli cell-only syndrome</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">testicular spermatozoa</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">processing</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">microfluidics</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">new technologies</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">genetics</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">exome</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">WES</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Y chromosome</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cancer</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">NOA</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">genes</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">general health</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ICSI</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">offspring health</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">microTESE</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">prediction model</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4143413-4</subfield><subfield code="a">Aufsatzsammlung</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Azoospermie</subfield><subfield code="0">(DE-588)4143820-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Colpi, Giovanni M.</subfield><subfield code="0">(DE-588)1266351922</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Caroppo, Ettore</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe, Hardcover</subfield><subfield code="z">978-3-0365-3433-6</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://directory.doabooks.org/handle/20.500.12854/81136</subfield><subfield code="x">Verlag</subfield><subfield code="z">kostenfrei</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.3390/books978-3-0365-3434-3</subfield><subfield code="x">Verlag</subfield><subfield code="z">kostenfrei</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-94-OAB</subfield></datafield><datafield tag="943" ind1="1" ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-033800072</subfield></datafield></record></collection> |
| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV048421785 |
| illustrated | Not Illustrated |
| index_date | 2024-07-03T20:27:52Z |
| indexdate | 2025-01-23T23:02:51Z |
| institution | BVB |
| isbn | 9783036534343 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-033800072 |
| oclc_num | 1344239027 |
| open_access_boolean | 1 |
| owner | DE-12 DE-210 DE-521 DE-1102 DE-1046 DE-1028 DE-1050 DE-573 DE-M347 DE-92 DE-1051 DE-898 DE-BY-UBR DE-859 DE-860 DE-1049 DE-861 DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-Re13 DE-BY-UBR DE-Y3 DE-255 DE-Y7 DE-Y2 DE-70 DE-2174 DE-127 DE-22 DE-BY-UBG DE-155 DE-BY-UBR DE-91 DE-BY-TUM DE-384 DE-473 DE-BY-UBG DE-19 DE-BY-UBM DE-355 DE-BY-UBR DE-703 DE-20 DE-706 DE-824 DE-29 DE-739 |
| owner_facet | DE-12 DE-210 DE-521 DE-1102 DE-1046 DE-1028 DE-1050 DE-573 DE-M347 DE-92 DE-1051 DE-898 DE-BY-UBR DE-859 DE-860 DE-1049 DE-861 DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-Re13 DE-BY-UBR DE-Y3 DE-255 DE-Y7 DE-Y2 DE-70 DE-2174 DE-127 DE-22 DE-BY-UBG DE-155 DE-BY-UBR DE-91 DE-BY-TUM DE-384 DE-473 DE-BY-UBG DE-19 DE-BY-UBM DE-355 DE-BY-UBR DE-703 DE-20 DE-706 DE-824 DE-29 DE-739 |
| physical | 1 Online-Ressource (157 Seiten) |
| psigel | ZDB-94-OAB |
| publishDate | 2022 |
| publishDateSearch | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | marc |
| spelling | Update on the management of non-obstructive azoospermia current evidence and unmet needs editors Giovanni M. Colpi, Ettore Caroppo Basel MDPI - Multidisciplinary Digital Publishing Institute [2022] The Hague OAPEN FOUNDATION © 2022 1 Online-Ressource (157 Seiten) txt rdacontent c rdamedia cr rdacarrier Titelrückseite: This is a reprint of articles from the Special Issue published online in the open access journal Journal of Clinical Medicine (ISSN 2077-0383) (available at: https://www.mdpi.com/journal/jcm/special_issues/NOA_Management). Azoospermia, defined as the absence of sperm in the ejaculate after examination of the centrifuged specimens, affects about 1% of the male population and 10–15% of infertile men. In about two-thirds of cases, this is caused by severe spermatogenic dysfunction, and it is commonly termed "nonobstructive azoospermia" (NOA) to differentiate it from the less severe form of azoospermia caused by the obstruction of the seminal tract (obstructive azoospermia—OA), the latter affecting the remaining one-third of cases. Managing patients with NOA is challenging due to the severity of spermatogenic dysfunction and the lack of medical treatments, with surgical retrieval of testicular sperm being the only way of enabling some of these patients to father their own biological children. In-depth clinical knowledge is key for supporting clinical reasoning and decision making when counselling patients with NOA, and surgical skill is required to maximize the outcome of surgical procedures that aim to retrieve testicular sperm. The present book is a collection of scientific papers published in a Special Issue of the Journal of Clinical Medicine, authored by some of the most influential researchers in the field. The Special Issue, and thus also this book, were conceived to provide early career reproductive urologists and endocrinologists with an update of the scientific evidence in the field, together with surgical tips. Azoospermie (DE-588)4143820-6 gnd rswk-swf nonobstructive azoospermia micro-TESE FSH treatment hormonal treatment testosterone level microdissection testicular sperm extraction non-obstructive azoospermia management infertility intracytoplasmic sperm injection testicular azoospermia sperm selection sperm cryopreservation in vitro maturation azoospermia diagnosis male infertility spermatogenic failure testis biopsy sperm retrieval genetic testing endocrine evaluation review hypogonadism Sertoli cell-only syndrome testicular spermatozoa processing microfluidics new technologies genetics exome WES Y chromosome cancer NOA genes general health ICSI offspring health microTESE prediction model (DE-588)4143413-4 Aufsatzsammlung gnd-content Azoospermie (DE-588)4143820-6 s DE-604 Colpi, Giovanni M. (DE-588)1266351922 edt Caroppo, Ettore edt Erscheint auch als Druck-Ausgabe, Hardcover 978-3-0365-3433-6 https://directory.doabooks.org/handle/20.500.12854/81136 Verlag kostenfrei Volltext https://doi.org/10.3390/books978-3-0365-3434-3 Verlag kostenfrei Volltext |
| spellingShingle | Update on the management of non-obstructive azoospermia current evidence and unmet needs Azoospermie (DE-588)4143820-6 gnd |
| subject_GND | (DE-588)4143820-6 (DE-588)4143413-4 |
| title | Update on the management of non-obstructive azoospermia current evidence and unmet needs |
| title_auth | Update on the management of non-obstructive azoospermia current evidence and unmet needs |
| title_exact_search | Update on the management of non-obstructive azoospermia current evidence and unmet needs |
| title_exact_search_txtP | Update on the management of non-obstructive azoospermia current evidence and unmet needs |
| title_full | Update on the management of non-obstructive azoospermia current evidence and unmet needs editors Giovanni M. Colpi, Ettore Caroppo |
| title_fullStr | Update on the management of non-obstructive azoospermia current evidence and unmet needs editors Giovanni M. Colpi, Ettore Caroppo |
| title_full_unstemmed | Update on the management of non-obstructive azoospermia current evidence and unmet needs editors Giovanni M. Colpi, Ettore Caroppo |
| title_short | Update on the management of non-obstructive azoospermia |
| title_sort | update on the management of non obstructive azoospermia current evidence and unmet needs |
| title_sub | current evidence and unmet needs |
| topic | Azoospermie (DE-588)4143820-6 gnd |
| topic_facet | Azoospermie Aufsatzsammlung |
| url | https://directory.doabooks.org/handle/20.500.12854/81136 https://doi.org/10.3390/books978-3-0365-3434-3 |
| work_keys_str_mv | AT colpigiovannim updateonthemanagementofnonobstructiveazoospermiacurrentevidenceandunmetneeds AT caroppoettore updateonthemanagementofnonobstructiveazoospermiacurrentevidenceandunmetneeds |