First in Fly: ‹i›Drosophila‹/i› Research and Biological Discovery
A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large num...
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge, MA
Harvard University Press
[2018]
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| Schlagworte: | |
| Online-Zugang: | FAW01 FAB01 FCO01 FHA01 FKE01 FLA01 UPA01 Volltext |
| Zusammenfassung: | A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. Written by a leader in the Drosophila research community, First in Fly celebrates key insights uncovered by investigators using this model organism. Stephanie Elizabeth Mohr draws on these "first in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease |
| Beschreibung: | Description based on online resource; title from PDF title page (publisher's Web site, viewed 24. Aug 2021) |
| Beschreibung: | 1 online resource (270 pages) 21 line illustrations, 1 table |
| ISBN: | 9780674984721 |
| DOI: | 10.4159/9780674984721 |
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| 520 | |a A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. Written by a leader in the Drosophila research community, First in Fly celebrates key insights uncovered by investigators using this model organism. Stephanie Elizabeth Mohr draws on these "first in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease | ||
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| isbn | 9780674984721 |
| language | English |
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| spelling | Mohr, Stephanie Elizabeth Verfasser aut First in Fly ‹i›Drosophila‹/i› Research and Biological Discovery Stephanie Elizabeth Mohr Cambridge, MA Harvard University Press [2018] © 2018 1 online resource (270 pages) 21 line illustrations, 1 table txt rdacontent c rdamedia cr rdacarrier Description based on online resource; title from PDF title page (publisher's Web site, viewed 24. Aug 2021) A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. Written by a leader in the Drosophila research community, First in Fly celebrates key insights uncovered by investigators using this model organism. Stephanie Elizabeth Mohr draws on these "first in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease In English SCIENCE / Life Sciences / Genetics & Genomics bisacsh Animal models in research Drosophila melanogaster Genetics Drosophila melanogaster Physiology https://doi.org/10.4159/9780674984721 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Mohr, Stephanie Elizabeth First in Fly ‹i›Drosophila‹/i› Research and Biological Discovery SCIENCE / Life Sciences / Genetics & Genomics bisacsh Animal models in research Drosophila melanogaster Genetics Drosophila melanogaster Physiology |
| title | First in Fly ‹i›Drosophila‹/i› Research and Biological Discovery |
| title_auth | First in Fly ‹i›Drosophila‹/i› Research and Biological Discovery |
| title_exact_search | First in Fly ‹i›Drosophila‹/i› Research and Biological Discovery |
| title_exact_search_txtP | First in Fly ‹i›Drosophila‹/i› Research and Biological Discovery |
| title_full | First in Fly ‹i›Drosophila‹/i› Research and Biological Discovery Stephanie Elizabeth Mohr |
| title_fullStr | First in Fly ‹i›Drosophila‹/i› Research and Biological Discovery Stephanie Elizabeth Mohr |
| title_full_unstemmed | First in Fly ‹i›Drosophila‹/i› Research and Biological Discovery Stephanie Elizabeth Mohr |
| title_short | First in Fly |
| title_sort | first in fly i drosophila i research and biological discovery |
| title_sub | ‹i›Drosophila‹/i› Research and Biological Discovery |
| topic | SCIENCE / Life Sciences / Genetics & Genomics bisacsh Animal models in research Drosophila melanogaster Genetics Drosophila melanogaster Physiology |
| topic_facet | SCIENCE / Life Sciences / Genetics & Genomics Animal models in research Drosophila melanogaster Genetics Drosophila melanogaster Physiology |
| url | https://doi.org/10.4159/9780674984721 |
| work_keys_str_mv | AT mohrstephanieelizabeth firstinflyidrosophilairesearchandbiologicaldiscovery |