Prions: a challenge for science, medicine and public health system
In the past decades, the public has been forced to revise its perception of the apparent triumph of modern hygiene and medical microbiology over infectious diseases. Not only have older infections reemerged but new epidemics, like AIDS, have lead to public uncertainty. With the onset of the bovine s...
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Schriftenreihe: | Contributions to microbiology
vol. 7 |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | In the past decades, the public has been forced to revise its perception of the apparent triumph of modern hygiene and medical microbiology over infectious diseases. Not only have older infections reemerged but new epidemics, like AIDS, have lead to public uncertainty. With the onset of the bovine spongiform encephalopathy epidemic in Great Britain, novel infectious agents came into the public spotlight, ones that do not cause classical inflammation but a slow and irreversible degeneration of the central nervous system. Sensational from a scientific point of view, these agents, called proteinaceous infectious organisms or prions, were shown to be self-replicating without nucleic acid sequences to encode genomic information.In this volume, leading scientists deal with the medical, scientific and public health questions that prion infections raise. Besides the 'prion or virus' discussion, the structures of prions and their molecular biological analysis as well as the questions of strain variations and species barrier are presented. The etiological, clinical and diagnostic aspects of transmissible spongiform encephalopathies are given special attention. The epidemiology of human and animal prion diseases, disease management and possibilities for inactivation of prions are discussed from a public health perspective. Directed at scientists, physicians and the public health sector, the monograph uses a multidisciplinary approach to present the latest findings on prion infection |
| Beschreibung: | 1 Online-Ressource (viii, 164 Seiten) illustrations |
| ISBN: | 0585440565 331800622X 9780585440569 9783318006223 |
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| 520 | 3 | |a In the past decades, the public has been forced to revise its perception of the apparent triumph of modern hygiene and medical microbiology over infectious diseases. Not only have older infections reemerged but new epidemics, like AIDS, have lead to public uncertainty. With the onset of the bovine spongiform encephalopathy epidemic in Great Britain, novel infectious agents came into the public spotlight, ones that do not cause classical inflammation but a slow and irreversible degeneration of the central nervous system. Sensational from a scientific point of view, these agents, called proteinaceous infectious organisms or prions, were shown to be self-replicating without nucleic acid sequences to encode genomic information.In this volume, leading scientists deal with the medical, scientific and public health questions that prion infections raise. Besides the 'prion or virus' discussion, the structures of prions and their molecular biological analysis as well as the questions of strain variations and species barrier are presented. The etiological, clinical and diagnostic aspects of transmissible spongiform encephalopathies are given special attention. The epidemiology of human and animal prion diseases, disease management and possibilities for inactivation of prions are discussed from a public health perspective. Directed at scientists, physicians and the public health sector, the monograph uses a multidisciplinary approach to present the latest findings on prion infection | |
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| spelling | Prions a challenge for science, medicine and public health system volume editors, Holger F. Rabenau, Jindrich Cinatl, Hans Wilhelm Doerr Basel ; New York Karger ©2001 1 Online-Ressource (viii, 164 Seiten) illustrations txt rdacontent c rdamedia cr rdacarrier Contributions to microbiology vol. 7 In the past decades, the public has been forced to revise its perception of the apparent triumph of modern hygiene and medical microbiology over infectious diseases. Not only have older infections reemerged but new epidemics, like AIDS, have lead to public uncertainty. With the onset of the bovine spongiform encephalopathy epidemic in Great Britain, novel infectious agents came into the public spotlight, ones that do not cause classical inflammation but a slow and irreversible degeneration of the central nervous system. Sensational from a scientific point of view, these agents, called proteinaceous infectious organisms or prions, were shown to be self-replicating without nucleic acid sequences to encode genomic information.In this volume, leading scientists deal with the medical, scientific and public health questions that prion infections raise. Besides the 'prion or virus' discussion, the structures of prions and their molecular biological analysis as well as the questions of strain variations and species barrier are presented. The etiological, clinical and diagnostic aspects of transmissible spongiform encephalopathies are given special attention. The epidemiology of human and animal prion diseases, disease management and possibilities for inactivation of prions are discussed from a public health perspective. Directed at scientists, physicians and the public health sector, the monograph uses a multidisciplinary approach to present the latest findings on prion infection Prion Diseases Prions Maladies à prions Prions (Virologie) HEALTH & FITNESS Diseases MEDICAL Neurology Prion diseases Spongiöse subakute Encephalopathie (DE-588)4277502-4 gnd rswk-swf Jakob-Creutzfeldt-Syndrom (DE-588)4220958-4 gnd rswk-swf Prion (DE-588)4353535-5 gnd rswk-swf Prionkrankheit (DE-588)4711087-9 gnd rswk-swf Electronic books (DE-588)4143413-4 Aufsatzsammlung gnd-content Prion (DE-588)4353535-5 s DE-604 Jakob-Creutzfeldt-Syndrom (DE-588)4220958-4 s Prionkrankheit (DE-588)4711087-9 s Spongiöse subakute Encephalopathie (DE-588)4277502-4 s Cinatl, Jindrich Sonstige oth Doerr, Hans Wilhelm Sonstige oth Rabenau, Holger F. Sonstige oth Erscheint auch als Druck-Ausgabe Prions Basel ; New York : Karger, ©2001 3805571240 https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=78904 Verlag kostenfrei Volltext |
| spellingShingle | Prions a challenge for science, medicine and public health system Prion Diseases Prions Maladies à prions Prions (Virologie) HEALTH & FITNESS Diseases MEDICAL Neurology Prion diseases Spongiöse subakute Encephalopathie (DE-588)4277502-4 gnd Jakob-Creutzfeldt-Syndrom (DE-588)4220958-4 gnd Prion (DE-588)4353535-5 gnd Prionkrankheit (DE-588)4711087-9 gnd |
| subject_GND | (DE-588)4277502-4 (DE-588)4220958-4 (DE-588)4353535-5 (DE-588)4711087-9 (DE-588)4143413-4 |
| title | Prions a challenge for science, medicine and public health system |
| title_auth | Prions a challenge for science, medicine and public health system |
| title_exact_search | Prions a challenge for science, medicine and public health system |
| title_exact_search_txtP | Prions a challenge for science, medicine and public health system |
| title_full | Prions a challenge for science, medicine and public health system volume editors, Holger F. Rabenau, Jindrich Cinatl, Hans Wilhelm Doerr |
| title_fullStr | Prions a challenge for science, medicine and public health system volume editors, Holger F. Rabenau, Jindrich Cinatl, Hans Wilhelm Doerr |
| title_full_unstemmed | Prions a challenge for science, medicine and public health system volume editors, Holger F. Rabenau, Jindrich Cinatl, Hans Wilhelm Doerr |
| title_short | Prions |
| title_sort | prions a challenge for science medicine and public health system |
| title_sub | a challenge for science, medicine and public health system |
| topic | Prion Diseases Prions Maladies à prions Prions (Virologie) HEALTH & FITNESS Diseases MEDICAL Neurology Prion diseases Spongiöse subakute Encephalopathie (DE-588)4277502-4 gnd Jakob-Creutzfeldt-Syndrom (DE-588)4220958-4 gnd Prion (DE-588)4353535-5 gnd Prionkrankheit (DE-588)4711087-9 gnd |
| topic_facet | Prion Diseases Prions Maladies à prions Prions (Virologie) HEALTH & FITNESS MEDICAL Prion diseases Spongiöse subakute Encephalopathie Jakob-Creutzfeldt-Syndrom Prion Prionkrankheit Aufsatzsammlung |
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