Myeloproliferative Neoplasms: Critical Concepts and Management
Myeloproliferative neoplasms (MPNs) are clonal stem cell diseases that, under the World Health Organization classification, are subcategorized into eight clinicopathologic entities. The current book focuses on three of these categories: polycythemia vera, essential thrombocythemia, and primary myelo...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2012
|
| Ausgabe: | 1st ed. 2012 |
| Schriftenreihe: | Hematologic Malignancies
|
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | Myeloproliferative neoplasms (MPNs) are clonal stem cell diseases that, under the World Health Organization classification, are subcategorized into eight clinicopathologic entities. The current book focuses on three of these categories: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. A number of important questions regarding the diagnosis, prognosis, and treatment of these diseases have arisen following the discovery of the JAK2 V617F mutation in the majority of patients with bcr/abl-negative MPNs. This book comprises evidence-based reviews and expert consensus results. It offers comprehensive coverage of relevant laboratory and clinical advances and places great emphasis on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field |
| Beschreibung: | 1 Online-Ressource (VIII, 240 Seiten 22 illus., 13 illus. in color.) |
| ISBN: | 9783642249891 |
| DOI: | 10.1007/978-3-642-24989-1 |
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| spelling | Myeloproliferative Neoplasms Critical Concepts and Management edited by Tiziano Barbui, Ayalew Tefferi 1st ed. 2012 Berlin, Heidelberg Springer Berlin Heidelberg 2012 1 Online-Ressource (VIII, 240 Seiten 22 illus., 13 illus. in color.) txt rdacontent c rdamedia cr rdacarrier Hematologic Malignancies Myeloproliferative neoplasms (MPNs) are clonal stem cell diseases that, under the World Health Organization classification, are subcategorized into eight clinicopathologic entities. The current book focuses on three of these categories: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. A number of important questions regarding the diagnosis, prognosis, and treatment of these diseases have arisen following the discovery of the JAK2 V617F mutation in the majority of patients with bcr/abl-negative MPNs. This book comprises evidence-based reviews and expert consensus results. It offers comprehensive coverage of relevant laboratory and clinical advances and places great emphasis on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field Hematology Internal Medicine Oncology Internal medicine Oncology Myeloproliferatives Syndrom (DE-588)4301911-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Myeloproliferatives Syndrom (DE-588)4301911-0 s DE-604 Barbui, Tiziano edt Tefferi, Ayalew edt Erscheint auch als Druck-Ausgabe 9783642249884 Erscheint auch als Druck-Ausgabe 9783642249907 Erscheint auch als Druck-Ausgabe 9783662520277 https://doi.org/10.1007/978-3-642-24989-1 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Myeloproliferative Neoplasms Critical Concepts and Management Hematology Internal Medicine Oncology Internal medicine Oncology Myeloproliferatives Syndrom (DE-588)4301911-0 gnd |
| subject_GND | (DE-588)4301911-0 (DE-588)4143413-4 |
| title | Myeloproliferative Neoplasms Critical Concepts and Management |
| title_auth | Myeloproliferative Neoplasms Critical Concepts and Management |
| title_exact_search | Myeloproliferative Neoplasms Critical Concepts and Management |
| title_exact_search_txtP | Myeloproliferative Neoplasms Critical Concepts and Management |
| title_full | Myeloproliferative Neoplasms Critical Concepts and Management edited by Tiziano Barbui, Ayalew Tefferi |
| title_fullStr | Myeloproliferative Neoplasms Critical Concepts and Management edited by Tiziano Barbui, Ayalew Tefferi |
| title_full_unstemmed | Myeloproliferative Neoplasms Critical Concepts and Management edited by Tiziano Barbui, Ayalew Tefferi |
| title_short | Myeloproliferative Neoplasms |
| title_sort | myeloproliferative neoplasms critical concepts and management |
| title_sub | Critical Concepts and Management |
| topic | Hematology Internal Medicine Oncology Internal medicine Oncology Myeloproliferatives Syndrom (DE-588)4301911-0 gnd |
| topic_facet | Hematology Internal Medicine Oncology Internal medicine Oncology Myeloproliferatives Syndrom Aufsatzsammlung |
| url | https://doi.org/10.1007/978-3-642-24989-1 |
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