NMR-based metabolomics: methods and protocols
This book provides broad coverage of nuclear magnetic resonance (NMR) spectroscopy-based methods and applications for the analysis of metabolites in a wide range of biological samples, from biofluids, cells, animal models, human, to plants and foods. The applications range from mechanistic understan...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
2019
|
| Ausgabe: | 1st ed. 2019 |
| Schriftenreihe: | Methods in Molecular Biology
2037 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | This book provides broad coverage of nuclear magnetic resonance (NMR) spectroscopy-based methods and applications for the analysis of metabolites in a wide range of biological samples, from biofluids, cells, animal models, human, to plants and foods. The applications range from mechanistic understanding, biomarker discovery, environmental studies, and drug discovery to nutrition, while NMR methods include global, targeted, and isotope tracer-based techniques. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, NMR-Based Metabolomics: Methods and Protocols serves as a wealth of information for beginners as well as advanced practitioners and also as stepping stones for further advances in the field of metabolomics |
| Beschreibung: | Overview of NMR Spectroscopy-Based Metabolomics: Opportunities and Challenges -- Analysis of Plasma, Serum, and Whole Blood Metabolites Using 1H NMR Spectroscopy -- Lipid Profiling Using 1H-NMR Spectroscopy -- High Resolution Magic Angle Spinning (HRMAS) NMR Methods in Metabolomics -- Practical Guidelines for 13C-Based NMR Metabolomics -- Analysis of Coenzymes and Antioxidants in Tissue and Blood Using 1D 1H NMR Spectroscopy -- UHPLC-QTOF-MS/MS-SPE-NMR: A Solution to the Metabolomics Grand Challenge of Higher-Throughput, Confident Metabolite Identifications -- Fast NMR Methods for Identification of Resonances and Metabolic Pathways -- Stable Isotope-Resolved Metabolomics by NMR -- Tracking Metabolic Rewiring of Cancer Metabolism in Humans Using Isotope-Resolved NMR -- NMR-Based Metabolomics in Cardiac Research -- Breast Cancer Metabolomics Using NMR -- NMR-Based Urinary Metabolomics Applications -- NMR-Based Metabolomics in Gallbladder Cancer Research -- Biomarker Discovery Using NMR-Based Metabolomics of Tissue -- NMR Metabolomics Protocols for Drug Discovery -- Practical Aspects of the Analysis of Low- and High-Field NMR Data from Environmental Samples -- NMR-Based Metabolomics of Food -- Plant Metabolomics Using NMR Spectroscopy -- Fast Quantitative 2D NMR for Untargeted and Targeted Metabolomics -- Targeted Metabolomics with Quantitative Dissolution Dynamic Nuclear Polarization -- Metabolic Profiling Using In Vivo High Field Flow NMR -- Tools for Enhanced NMR-Based Metabolomics Analysis -- Automated Tools for the Analysis of 1D and 2D NMR Spectra -- Processing and Analysis of Untargeted Multi-Cohort NMR Data -- Advanced Statistical Methods for NMR-Based Metabolomics |
| Beschreibung: | 1 Online-Ressource (XIV, 489 Seiten) Illustrationen |
| ISBN: | 9781493996902 |
| DOI: | 10.1007/978-1-4939-9690-2 |
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| spelling | NMR-based metabolomics methods and protocols edited by G. A. Nagana Gowda, Daniel Raftery 1st ed. 2019 New York, NY Springer New York 2019 1 Online-Ressource (XIV, 489 Seiten) Illustrationen txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 2037 Overview of NMR Spectroscopy-Based Metabolomics: Opportunities and Challenges -- Analysis of Plasma, Serum, and Whole Blood Metabolites Using 1H NMR Spectroscopy -- Lipid Profiling Using 1H-NMR Spectroscopy -- High Resolution Magic Angle Spinning (HRMAS) NMR Methods in Metabolomics -- Practical Guidelines for 13C-Based NMR Metabolomics -- Analysis of Coenzymes and Antioxidants in Tissue and Blood Using 1D 1H NMR Spectroscopy -- UHPLC-QTOF-MS/MS-SPE-NMR: A Solution to the Metabolomics Grand Challenge of Higher-Throughput, Confident Metabolite Identifications -- Fast NMR Methods for Identification of Resonances and Metabolic Pathways -- Stable Isotope-Resolved Metabolomics by NMR -- Tracking Metabolic Rewiring of Cancer Metabolism in Humans Using Isotope-Resolved NMR -- NMR-Based Metabolomics in Cardiac Research -- Breast Cancer Metabolomics Using NMR -- NMR-Based Urinary Metabolomics Applications -- NMR-Based Metabolomics in Gallbladder Cancer Research -- Biomarker Discovery Using NMR-Based Metabolomics of Tissue -- NMR Metabolomics Protocols for Drug Discovery -- Practical Aspects of the Analysis of Low- and High-Field NMR Data from Environmental Samples -- NMR-Based Metabolomics of Food -- Plant Metabolomics Using NMR Spectroscopy -- Fast Quantitative 2D NMR for Untargeted and Targeted Metabolomics -- Targeted Metabolomics with Quantitative Dissolution Dynamic Nuclear Polarization -- Metabolic Profiling Using In Vivo High Field Flow NMR -- Tools for Enhanced NMR-Based Metabolomics Analysis -- Automated Tools for the Analysis of 1D and 2D NMR Spectra -- Processing and Analysis of Untargeted Multi-Cohort NMR Data -- Advanced Statistical Methods for NMR-Based Metabolomics This book provides broad coverage of nuclear magnetic resonance (NMR) spectroscopy-based methods and applications for the analysis of metabolites in a wide range of biological samples, from biofluids, cells, animal models, human, to plants and foods. The applications range from mechanistic understanding, biomarker discovery, environmental studies, and drug discovery to nutrition, while NMR methods include global, targeted, and isotope tracer-based techniques. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, NMR-Based Metabolomics: Methods and Protocols serves as a wealth of information for beginners as well as advanced practitioners and also as stepping stones for further advances in the field of metabolomics Metabolism Spectroscopy Nagana Gowda, G. A. (DE-588)1196024219 edt Raftery, Daniel (DE-588)1196024553 edt Erscheint auch als Druck-Ausgabe 978-1-4939-9692-6 https://doi.org/10.1007/978-1-4939-9690-2 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | NMR-based metabolomics methods and protocols Metabolism Spectroscopy |
| title | NMR-based metabolomics methods and protocols |
| title_auth | NMR-based metabolomics methods and protocols |
| title_exact_search | NMR-based metabolomics methods and protocols |
| title_exact_search_txtP | NMR-based metabolomics methods and protocols |
| title_full | NMR-based metabolomics methods and protocols edited by G. A. Nagana Gowda, Daniel Raftery |
| title_fullStr | NMR-based metabolomics methods and protocols edited by G. A. Nagana Gowda, Daniel Raftery |
| title_full_unstemmed | NMR-based metabolomics methods and protocols edited by G. A. Nagana Gowda, Daniel Raftery |
| title_short | NMR-based metabolomics |
| title_sort | nmr based metabolomics methods and protocols |
| title_sub | methods and protocols |
| topic | Metabolism Spectroscopy |
| topic_facet | Metabolism Spectroscopy |
| url | https://doi.org/10.1007/978-1-4939-9690-2 |
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