Rheumatoid arthritis: methods and protocols
This volume provides a summary of the standard laboratory protocols and methodology commonly used in basic and translational studies in the field of rheumatoid arthritis (RA) treatment. Chapters detail including basic RA models, evaluation of disease activity and immunological status, systemic drug...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
2018
|
| Ausgabe: | 1st ed. 2018 |
| Schriftenreihe: | Methods in Molecular Biology
1868 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | This volume provides a summary of the standard laboratory protocols and methodology commonly used in basic and translational studies in the field of rheumatoid arthritis (RA) treatment. Chapters detail including basic RA models, evaluation of disease activity and immunological status, systemic drug delivery, and new research tools. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Rheumatoid Arthritis: Methods and Protocols aims to be a basic manual for clinical researchers who are just getting started in the field of intervention study |
| Beschreibung: | Collagen-induced Arthritis Models -- Human Xenograft Model -- Long-term Constant Subcutaneous Drug Administration -- Clinical Scoring of Disease Activity in Animal Models -- Histological Analysis of Arthritic Joints -- Preparation of Joint Extracts -- Production of Immunizing Antigen Proteoliposome Using Cell-free Protein Synthesis System -- Re-construction of Protein/Liposome Complex -- Production of Neutralizing Antibody -- Autoantibody Profiling Using Human Autoantigen Protein Array and AlphaScreen -- Generation of Specific Aptamers -- Production of Lentiviral Particles -- RNA Interference Ex Vivo -- Lentiviral-mediated Systemic RNA Interference in vivo -- Mesenchymal Stem Cell Engineering -- Screening of Ca2+ Influx in Lymphocytes -- Single-cell Ca2+ Imaging -- Electrophysiological Methods to Measure Ca2+ Current -- The Functional Assessment of T cells -- Release of Antibodies and Cytokines from B cells -- Evaluation of Autoreactive Responses -- Bone-resorption Activity in Mature Osteoclasts -- Animal Models of Vasculitis -- Design an Intervention Study -- Assessment of Disease Activity, Structural Damage, and Function in Rheumatoid Arthritis |
| Beschreibung: | 1 Online-Ressource (IX, 253 Seiten) Illustrationen |
| ISBN: | 9781493988020 |
| DOI: | 10.1007/978-1-4939-8802-0 |
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| edition | 1st ed. 2018 |
| format | Electronic eBook |
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| index_date | 2024-07-03T18:44:15Z |
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| isbn | 9781493988020 |
| language | English |
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| spelling | Rheumatoid arthritis methods and protocols edited by Shuang Liu 1st ed. 2018 New York, NY Springer New York 2018 1 Online-Ressource (IX, 253 Seiten) Illustrationen txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 1868 Collagen-induced Arthritis Models -- Human Xenograft Model -- Long-term Constant Subcutaneous Drug Administration -- Clinical Scoring of Disease Activity in Animal Models -- Histological Analysis of Arthritic Joints -- Preparation of Joint Extracts -- Production of Immunizing Antigen Proteoliposome Using Cell-free Protein Synthesis System -- Re-construction of Protein/Liposome Complex -- Production of Neutralizing Antibody -- Autoantibody Profiling Using Human Autoantigen Protein Array and AlphaScreen -- Generation of Specific Aptamers -- Production of Lentiviral Particles -- RNA Interference Ex Vivo -- Lentiviral-mediated Systemic RNA Interference in vivo -- Mesenchymal Stem Cell Engineering -- Screening of Ca2+ Influx in Lymphocytes -- Single-cell Ca2+ Imaging -- Electrophysiological Methods to Measure Ca2+ Current -- The Functional Assessment of T cells -- Release of Antibodies and Cytokines from B cells -- Evaluation of Autoreactive Responses -- Bone-resorption Activity in Mature Osteoclasts -- Animal Models of Vasculitis -- Design an Intervention Study -- Assessment of Disease Activity, Structural Damage, and Function in Rheumatoid Arthritis This volume provides a summary of the standard laboratory protocols and methodology commonly used in basic and translational studies in the field of rheumatoid arthritis (RA) treatment. Chapters detail including basic RA models, evaluation of disease activity and immunological status, systemic drug delivery, and new research tools. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Rheumatoid Arthritis: Methods and Protocols aims to be a basic manual for clinical researchers who are just getting started in the field of intervention study Molecular biology Liu, Shuang ca. 20./21. Jh. (DE-588)1246979322 edt Erscheint auch als Druck-Ausgabe 978-1-4939-8801-3 Erscheint auch als Druck-Ausgabe 978-1-4939-8803-7 Erscheint auch als Druck-Ausgabe 978-1-4939-9393-2 https://doi.org/10.1007/978-1-4939-8802-0 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Rheumatoid arthritis methods and protocols Molecular biology |
| title | Rheumatoid arthritis methods and protocols |
| title_auth | Rheumatoid arthritis methods and protocols |
| title_exact_search | Rheumatoid arthritis methods and protocols |
| title_exact_search_txtP | Rheumatoid arthritis methods and protocols |
| title_full | Rheumatoid arthritis methods and protocols edited by Shuang Liu |
| title_fullStr | Rheumatoid arthritis methods and protocols edited by Shuang Liu |
| title_full_unstemmed | Rheumatoid arthritis methods and protocols edited by Shuang Liu |
| title_short | Rheumatoid arthritis |
| title_sort | rheumatoid arthritis methods and protocols |
| title_sub | methods and protocols |
| topic | Molecular biology |
| topic_facet | Molecular biology |
| url | https://doi.org/10.1007/978-1-4939-8802-0 |
| work_keys_str_mv | AT liushuang rheumatoidarthritismethodsandprotocols |