Targeted drug delivery: methods and protocols
This volume looks at the latest techniques used to enable therapeutic molecules to be targeted for site-specific delivery. The chapters in this book discuss topics such as approaches to express biologically derived and synthetic nanocarriers; strategies to assist in nanocarrier targeting to specific...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer US
2018
|
| Ausgabe: | 1st ed. 2018 |
| Schriftenreihe: | Methods in Molecular Biology
1831 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | This volume looks at the latest techniques used to enable therapeutic molecules to be targeted for site-specific delivery. The chapters in this book discuss topics such as approaches to express biologically derived and synthetic nanocarriers; strategies to assist in nanocarrier targeting to specific cells and tissues; and methods for evaluating delivery and efficiency for new classes of agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Targeted Drug Delivery: Methods and Protocols is a valuable resource for anyone interested in understanding the diversity of methods used in this evolving field |
| Beschreibung: | Synthesis of Cationic Polymer Libraries for Gene Delivery using Diglycidyl Ethers -- Generation of Ultra-Small PLGA Nanoparticles by Sequential Centrifugation -- Construction of Bacteria-Based Cargo Carriers for Targeted Cancer Therapy -- Production of Extracellular Vesicles Loaded with Therapeutic Cargo -- Delivery of Cytotoxic Mesenchymal Stem Cells with Biodegradable Scaffolds for Treatment of Postoperative Brain Cancer -- Nanoparticles for Targeted Drug Delivery to Cancer Stem-Like Cells and Tumor -- Exploiting Phage Display for Development of Novel Cellular Targeting Strategies -- CD44 Targeted Lipid Nanoparticles for MicroRNA Therapy -- Ultrasound and Microbubble-Mediated Blood-Brain Barrier Disruption for Targeted Delivery of Therapeutics to the Brain -- In Vitro Validation of Targeting and Comparison to Mathematical Modeling -- Enzyme-Linked Immunosorbent Assay to Quantify Targeting Molecules on Nanoparticles -- Tunable Collagen Microfluidic Platform to Study Nanoparticle Transport in the Tumor Microenvironment -- Utilizing the Lung as a Model to Study Nanoparticle Based Drug Delivery Systems -- Non-Enzymatic Tissue Homogenization for Biodistribution Analysis -- Methods and Study Designs for Characterizing the Pharmacokinetics and Pharmacodynamics of Carrier-Mediated Agents |
| Beschreibung: | 1 Online-Ressource (XI, 230 Seiten) Illustrationen |
| ISBN: | 9781493986613 |
| DOI: | 10.1007/978-1-4939-8661-3 |
Internformat
MARC
| LEADER | 00000nmm a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV047619042 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 211130s2018 |||| o||u| ||||||eng d | ||
| 020 | |a 9781493986613 |c Online |9 978-1-4939-8661-3 | ||
| 024 | 7 | |a 10.1007/978-1-4939-8661-3 |2 doi | |
| 035 | |a (ZDB-2-PRO)978-1-4939-8661-3 | ||
| 035 | |a (OCoLC)1286872607 | ||
| 035 | |a (DE-599)BVBBV047619042 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 |a DE-91 | ||
| 082 | 0 | |a 615 | |
| 084 | |a VX 8560 |0 (DE-625)147831:253 |2 rvk | ||
| 245 | 1 | 0 | |a Targeted drug delivery |b methods and protocols |c edited by Rachael W. Sirianni, Bahareh Behkam |
| 250 | |a 1st ed. 2018 | ||
| 264 | 1 | |a New York, NY |b Springer US |c 2018 | |
| 300 | |a 1 Online-Ressource (XI, 230 Seiten) |b Illustrationen | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 490 | 0 | |a Methods in Molecular Biology | |
| 490 | 0 | |a 1831 | |
| 500 | |a Synthesis of Cationic Polymer Libraries for Gene Delivery using Diglycidyl Ethers -- Generation of Ultra-Small PLGA Nanoparticles by Sequential Centrifugation -- Construction of Bacteria-Based Cargo Carriers for Targeted Cancer Therapy -- Production of Extracellular Vesicles Loaded with Therapeutic Cargo -- Delivery of Cytotoxic Mesenchymal Stem Cells with Biodegradable Scaffolds for Treatment of Postoperative Brain Cancer -- Nanoparticles for Targeted Drug Delivery to Cancer Stem-Like Cells and Tumor -- Exploiting Phage Display for Development of Novel Cellular Targeting Strategies -- CD44 Targeted Lipid Nanoparticles for MicroRNA Therapy -- Ultrasound and Microbubble-Mediated Blood-Brain Barrier Disruption for Targeted Delivery of Therapeutics to the Brain -- In Vitro Validation of Targeting and Comparison to Mathematical Modeling -- Enzyme-Linked Immunosorbent Assay to Quantify Targeting Molecules on Nanoparticles -- Tunable Collagen Microfluidic Platform to Study Nanoparticle Transport in the Tumor Microenvironment -- Utilizing the Lung as a Model to Study Nanoparticle Based Drug Delivery Systems -- Non-Enzymatic Tissue Homogenization for Biodistribution Analysis -- Methods and Study Designs for Characterizing the Pharmacokinetics and Pharmacodynamics of Carrier-Mediated Agents | ||
| 520 | |a This volume looks at the latest techniques used to enable therapeutic molecules to be targeted for site-specific delivery. The chapters in this book discuss topics such as approaches to express biologically derived and synthetic nanocarriers; strategies to assist in nanocarrier targeting to specific cells and tissues; and methods for evaluating delivery and efficiency for new classes of agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Targeted Drug Delivery: Methods and Protocols is a valuable resource for anyone interested in understanding the diversity of methods used in this evolving field | ||
| 650 | 4 | |a Pharmacology | |
| 700 | 1 | |a Sirianni, Rachael |d ca. 20./21. Jh. |0 (DE-588)1246793849 |4 edt | |
| 700 | 1 | |a Behkam, Bahareh |d ca. 20./21. Jh. |0 (DE-588)1246794055 |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 978-1-4939-8659-0 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 978-1-4939-8660-6 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 978-1-4939-9357-4 |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-1-4939-8661-3 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
| 912 | |a ZDB-2-PRO | ||
| 999 | |a oai:aleph.bib-bvb.de:BVB01-033003725 | ||
| 966 | e | |u https://doi.org/10.1007/978-1-4939-8661-3 |l UBR01 |p ZDB-2-PRO |x Verlag |3 Volltext | |
| 966 | e | |u https://doi.org/10.1007/978-1-4939-8661-3 |l TUM01 |p ZDB-2-PRO |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804183055529672705 |
|---|---|
| adam_txt | |
| any_adam_object | |
| any_adam_object_boolean | |
| author2 | Sirianni, Rachael ca. 20./21. Jh Behkam, Bahareh ca. 20./21. Jh |
| author2_role | edt edt |
| author2_variant | r s rs b b bb |
| author_GND | (DE-588)1246793849 (DE-588)1246794055 |
| author_facet | Sirianni, Rachael ca. 20./21. Jh Behkam, Bahareh ca. 20./21. Jh |
| building | Verbundindex |
| bvnumber | BV047619042 |
| classification_rvk | VX 8560 |
| collection | ZDB-2-PRO |
| ctrlnum | (ZDB-2-PRO)978-1-4939-8661-3 (OCoLC)1286872607 (DE-599)BVBBV047619042 |
| dewey-full | 615 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615 |
| dewey-search | 615 |
| dewey-sort | 3615 |
| dewey-tens | 610 - Medicine and health |
| discipline | Chemie / Pharmazie Medizin |
| discipline_str_mv | Chemie / Pharmazie Medizin |
| doi_str_mv | 10.1007/978-1-4939-8661-3 |
| edition | 1st ed. 2018 |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03946nmm a2200469zc 4500</leader><controlfield tag="001">BV047619042</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">211130s2018 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781493986613</subfield><subfield code="c">Online</subfield><subfield code="9">978-1-4939-8661-3</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/978-1-4939-8661-3</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-2-PRO)978-1-4939-8661-3</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1286872607</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV047619042</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield><subfield code="a">DE-91</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">615</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VX 8560</subfield><subfield code="0">(DE-625)147831:253</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Targeted drug delivery</subfield><subfield code="b">methods and protocols</subfield><subfield code="c">edited by Rachael W. Sirianni, Bahareh Behkam</subfield></datafield><datafield tag="250" ind1=" " ind2=" "><subfield code="a">1st ed. 2018</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">New York, NY</subfield><subfield code="b">Springer US</subfield><subfield code="c">2018</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (XI, 230 Seiten)</subfield><subfield code="b">Illustrationen</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Methods in Molecular Biology</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">1831</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Synthesis of Cationic Polymer Libraries for Gene Delivery using Diglycidyl Ethers -- Generation of Ultra-Small PLGA Nanoparticles by Sequential Centrifugation -- Construction of Bacteria-Based Cargo Carriers for Targeted Cancer Therapy -- Production of Extracellular Vesicles Loaded with Therapeutic Cargo -- Delivery of Cytotoxic Mesenchymal Stem Cells with Biodegradable Scaffolds for Treatment of Postoperative Brain Cancer -- Nanoparticles for Targeted Drug Delivery to Cancer Stem-Like Cells and Tumor -- Exploiting Phage Display for Development of Novel Cellular Targeting Strategies -- CD44 Targeted Lipid Nanoparticles for MicroRNA Therapy -- Ultrasound and Microbubble-Mediated Blood-Brain Barrier Disruption for Targeted Delivery of Therapeutics to the Brain -- In Vitro Validation of Targeting and Comparison to Mathematical Modeling -- Enzyme-Linked Immunosorbent Assay to Quantify Targeting Molecules on Nanoparticles -- Tunable Collagen Microfluidic Platform to Study Nanoparticle Transport in the Tumor Microenvironment -- Utilizing the Lung as a Model to Study Nanoparticle Based Drug Delivery Systems -- Non-Enzymatic Tissue Homogenization for Biodistribution Analysis -- Methods and Study Designs for Characterizing the Pharmacokinetics and Pharmacodynamics of Carrier-Mediated Agents</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">This volume looks at the latest techniques used to enable therapeutic molecules to be targeted for site-specific delivery. The chapters in this book discuss topics such as approaches to express biologically derived and synthetic nanocarriers; strategies to assist in nanocarrier targeting to specific cells and tissues; and methods for evaluating delivery and efficiency for new classes of agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Targeted Drug Delivery: Methods and Protocols is a valuable resource for anyone interested in understanding the diversity of methods used in this evolving field</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacology</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sirianni, Rachael</subfield><subfield code="d">ca. 20./21. Jh.</subfield><subfield code="0">(DE-588)1246793849</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Behkam, Bahareh</subfield><subfield code="d">ca. 20./21. Jh.</subfield><subfield code="0">(DE-588)1246794055</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">978-1-4939-8659-0</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">978-1-4939-8660-6</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">978-1-4939-9357-4</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1007/978-1-4939-8661-3</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-PRO</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-033003725</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-4939-8661-3</subfield><subfield code="l">UBR01</subfield><subfield code="p">ZDB-2-PRO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-4939-8661-3</subfield><subfield code="l">TUM01</subfield><subfield code="p">ZDB-2-PRO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| id | DE-604.BV047619042 |
| illustrated | Not Illustrated |
| index_date | 2024-07-03T18:42:15Z |
| indexdate | 2024-07-10T09:17:22Z |
| institution | BVB |
| isbn | 9781493986613 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-033003725 |
| oclc_num | 1286872607 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-91 DE-BY-TUM |
| owner_facet | DE-355 DE-BY-UBR DE-91 DE-BY-TUM |
| physical | 1 Online-Ressource (XI, 230 Seiten) Illustrationen |
| psigel | ZDB-2-PRO |
| publishDate | 2018 |
| publishDateSearch | 2018 |
| publishDateSort | 2018 |
| publisher | Springer US |
| record_format | marc |
| series2 | Methods in Molecular Biology 1831 |
| spelling | Targeted drug delivery methods and protocols edited by Rachael W. Sirianni, Bahareh Behkam 1st ed. 2018 New York, NY Springer US 2018 1 Online-Ressource (XI, 230 Seiten) Illustrationen txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 1831 Synthesis of Cationic Polymer Libraries for Gene Delivery using Diglycidyl Ethers -- Generation of Ultra-Small PLGA Nanoparticles by Sequential Centrifugation -- Construction of Bacteria-Based Cargo Carriers for Targeted Cancer Therapy -- Production of Extracellular Vesicles Loaded with Therapeutic Cargo -- Delivery of Cytotoxic Mesenchymal Stem Cells with Biodegradable Scaffolds for Treatment of Postoperative Brain Cancer -- Nanoparticles for Targeted Drug Delivery to Cancer Stem-Like Cells and Tumor -- Exploiting Phage Display for Development of Novel Cellular Targeting Strategies -- CD44 Targeted Lipid Nanoparticles for MicroRNA Therapy -- Ultrasound and Microbubble-Mediated Blood-Brain Barrier Disruption for Targeted Delivery of Therapeutics to the Brain -- In Vitro Validation of Targeting and Comparison to Mathematical Modeling -- Enzyme-Linked Immunosorbent Assay to Quantify Targeting Molecules on Nanoparticles -- Tunable Collagen Microfluidic Platform to Study Nanoparticle Transport in the Tumor Microenvironment -- Utilizing the Lung as a Model to Study Nanoparticle Based Drug Delivery Systems -- Non-Enzymatic Tissue Homogenization for Biodistribution Analysis -- Methods and Study Designs for Characterizing the Pharmacokinetics and Pharmacodynamics of Carrier-Mediated Agents This volume looks at the latest techniques used to enable therapeutic molecules to be targeted for site-specific delivery. The chapters in this book discuss topics such as approaches to express biologically derived and synthetic nanocarriers; strategies to assist in nanocarrier targeting to specific cells and tissues; and methods for evaluating delivery and efficiency for new classes of agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Targeted Drug Delivery: Methods and Protocols is a valuable resource for anyone interested in understanding the diversity of methods used in this evolving field Pharmacology Sirianni, Rachael ca. 20./21. Jh. (DE-588)1246793849 edt Behkam, Bahareh ca. 20./21. Jh. (DE-588)1246794055 edt Erscheint auch als Druck-Ausgabe 978-1-4939-8659-0 Erscheint auch als Druck-Ausgabe 978-1-4939-8660-6 Erscheint auch als Druck-Ausgabe 978-1-4939-9357-4 https://doi.org/10.1007/978-1-4939-8661-3 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Targeted drug delivery methods and protocols Pharmacology |
| title | Targeted drug delivery methods and protocols |
| title_auth | Targeted drug delivery methods and protocols |
| title_exact_search | Targeted drug delivery methods and protocols |
| title_exact_search_txtP | Targeted drug delivery methods and protocols |
| title_full | Targeted drug delivery methods and protocols edited by Rachael W. Sirianni, Bahareh Behkam |
| title_fullStr | Targeted drug delivery methods and protocols edited by Rachael W. Sirianni, Bahareh Behkam |
| title_full_unstemmed | Targeted drug delivery methods and protocols edited by Rachael W. Sirianni, Bahareh Behkam |
| title_short | Targeted drug delivery |
| title_sort | targeted drug delivery methods and protocols |
| title_sub | methods and protocols |
| topic | Pharmacology |
| topic_facet | Pharmacology |
| url | https://doi.org/10.1007/978-1-4939-8661-3 |
| work_keys_str_mv | AT siriannirachael targeteddrugdeliverymethodsandprotocols AT behkambahareh targeteddrugdeliverymethodsandprotocols |