Understanding DNA ancestry:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Cambridge ; New York ; Port Melbourne ; New Delhi ; Singapore
Cambridge University Press
2022
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| Schriftenreihe: | Understanding life
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | xiii, 152 Seiten Illustrationen, Diagramme |
| ISBN: | 9781108816038 9781108841986 |
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Datensatz im Suchindex
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|---|---|
| adam_text | Contents Foreword Acknowledgments 1 page xv xvi Introduction 1 Familial and Historical Genealogy The Birth of Genome Sequencing Goal for the Book The Varieties of Ancestry Structure of the Book 2 2 3 4 6 2 The Business of DNA Ancestry The First DNA Ancestry Company Growth of the Digital Ancestry Sector Ancestry and Health Expanding the Types of Genetic Tests Behind Consumer Interest in Ancestry Tests 3 What Our Genomes Tell Us about the Geographical Origins and Movements of Early Human Populations A Hypothetical Case of Isolated Populations The Evolution of Homo sapiens Genetic Diversity in the Human Population 4 The Science behind DNA Ancestry Testing Allele Frequencies and Gene Variants 8 8 9 11 13 14 17 18 20 22 26 26
xii CONTENTS Patents on Inferring Ancestry from DNA Ancestry Markers Validation of Ancestry Inference Reference Panels Allele Frequencies in Populations Stages for Inferring Ancestry 5 Ancestry Informative Markers Forensic Applications of Genetic Markers From Forensic to Ancestry Markers Mitochondrial DNA Markers Y Chromosome Ancestral Markers Autosomal SNP Ancestry Markers G Ancestry DNA Population Reference Panels Proprietary Reference Panels Validation of Reference Panels 7 41 42 43 44 45 46 50 51 55 Comparing a Donor’s DNA toReference Panel Populations BO DNA Variants Population-Specific Variants Population Frequencies of Variantsand FST Statistics 60 63 66 8 Probing Your DNA Analysis of Customer DNA and Microarrays Optical Fibers and DNA Probes 9 Forensic Applications of Ancestry DNA Results Discovery of DNA Identification Method The Grim Sleeper The Golden State Killer Identity by Descent Phenotyping 10 27 29 33 34 35 36 73 74 76 79 79 80 81 83 86 Privacy, Personal Identity, and Legal Issues 88 Ownership of One s Cells and Genetic Information Ancestry Companies and the Privacy of Genetic Data 88 90
CONTENTS Advertising Claims Forensic Applications and Privacy Personal Identity through DNA Tests Race and DNA Ancestry 11 Discovering Unknown, Missing, or Mistaken Relatives DNA and Paternity Claims Hidden Family Secrets Family Ethnicity: Hidden Secrets Secret Sperm Breaking the Pure Ethnic Descent xiii 92 93 98 102 108 106 110 112 113 115 12 Accuracy, Consistency, and Validation of DNA Ancestry Tests 118 Comparing Different Company Ancestry Results DNA Markers and Ancestry Regions Ancestry Tests with Twins Self-Declared Ancestry vs. Genomic Ancestry 118 120 121 124 13 Conclusion Summary of Common Misunderstandings References Index 128 129 131 146
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| adam_txt |
Contents Foreword Acknowledgments 1 page xv xvi Introduction 1 Familial and Historical Genealogy The Birth of Genome Sequencing Goal for the Book The Varieties of Ancestry Structure of the Book 2 2 3 4 6 2 The Business of DNA Ancestry The First DNA Ancestry Company Growth of the Digital Ancestry Sector Ancestry and Health Expanding the Types of Genetic Tests Behind Consumer Interest in Ancestry Tests 3 What Our Genomes Tell Us about the Geographical Origins and Movements of Early Human Populations A Hypothetical Case of Isolated Populations The Evolution of Homo sapiens Genetic Diversity in the Human Population 4 The Science behind DNA Ancestry Testing Allele Frequencies and Gene Variants 8 8 9 11 13 14 17 18 20 22 26 26
xii CONTENTS Patents on Inferring Ancestry from DNA Ancestry Markers Validation of Ancestry Inference Reference Panels Allele Frequencies in Populations Stages for Inferring Ancestry 5 Ancestry Informative Markers Forensic Applications of Genetic Markers From Forensic to Ancestry Markers Mitochondrial DNA Markers Y Chromosome Ancestral Markers Autosomal SNP Ancestry Markers G Ancestry DNA Population Reference Panels Proprietary Reference Panels Validation of Reference Panels 7 41 42 43 44 45 46 50 51 55 Comparing a Donor’s DNA toReference Panel Populations BO DNA Variants Population-Specific Variants Population Frequencies of Variantsand FST Statistics 60 63 66 8 Probing Your DNA Analysis of Customer DNA and Microarrays Optical Fibers and DNA Probes 9 Forensic Applications of Ancestry DNA Results Discovery of DNA Identification Method The Grim Sleeper The Golden State Killer Identity by Descent Phenotyping 10 27 29 33 34 35 36 73 74 76 79 79 80 81 83 86 Privacy, Personal Identity, and Legal Issues 88 Ownership of One's Cells and Genetic Information Ancestry Companies and the Privacy of Genetic Data 88 90
CONTENTS Advertising Claims Forensic Applications and Privacy Personal Identity through DNA Tests Race and DNA Ancestry 11 Discovering Unknown, Missing, or Mistaken Relatives DNA and Paternity Claims Hidden Family Secrets Family Ethnicity: Hidden Secrets Secret Sperm Breaking the Pure Ethnic Descent xiii 92 93 98 102 108 106 110 112 113 115 12 Accuracy, Consistency, and Validation of DNA Ancestry Tests 118 Comparing Different Company Ancestry Results DNA Markers and Ancestry Regions Ancestry Tests with Twins Self-Declared Ancestry vs. Genomic Ancestry 118 120 121 124 13 Conclusion Summary of Common Misunderstandings References Index 128 129 131 146 |
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| ctrlnum | (OCoLC)1310253027 (DE-599)HEB480093571 |
| discipline | Biologie |
| discipline_str_mv | Biologie |
| format | Book |
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| illustrated | Illustrated |
| index_date | 2024-07-03T18:35:19Z |
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| isbn | 9781108816038 9781108841986 |
| language | English |
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| publishDate | 2022 |
| publishDateSearch | 2022 |
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| publisher | Cambridge University Press |
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| series2 | Understanding life |
| spelling | Krimsky, Sheldon 1941- Verfasser (DE-588)110239100X aut Understanding DNA ancestry Sheldon Krimsky (Tufts University, Massachusetts) DNA ancestry Cambridge ; New York ; Port Melbourne ; New Delhi ; Singapore Cambridge University Press 2022 xiii, 152 Seiten Illustrationen, Diagramme txt rdacontent n rdamedia nc rdacarrier Understanding life Genealogie (DE-588)4020097-8 gnd rswk-swf DNS (DE-588)4070512-2 gnd rswk-swf Kommerzialisierung (DE-588)4127776-4 gnd rswk-swf Genanalyse (DE-588)4200230-8 gnd rswk-swf Genealogie (DE-588)4020097-8 s Genanalyse (DE-588)4200230-8 s DNS (DE-588)4070512-2 s Kommerzialisierung (DE-588)4127776-4 s DE-604 Digitalisierung BSB München - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032973556&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
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| subject_GND | (DE-588)4020097-8 (DE-588)4070512-2 (DE-588)4127776-4 (DE-588)4200230-8 |
| title | Understanding DNA ancestry |
| title_alt | DNA ancestry |
| title_auth | Understanding DNA ancestry |
| title_exact_search | Understanding DNA ancestry |
| title_exact_search_txtP | Understanding DNA ancestry |
| title_full | Understanding DNA ancestry Sheldon Krimsky (Tufts University, Massachusetts) |
| title_fullStr | Understanding DNA ancestry Sheldon Krimsky (Tufts University, Massachusetts) |
| title_full_unstemmed | Understanding DNA ancestry Sheldon Krimsky (Tufts University, Massachusetts) |
| title_short | Understanding DNA ancestry |
| title_sort | understanding dna ancestry |
| topic | Genealogie (DE-588)4020097-8 gnd DNS (DE-588)4070512-2 gnd Kommerzialisierung (DE-588)4127776-4 gnd Genanalyse (DE-588)4200230-8 gnd |
| topic_facet | Genealogie DNS Kommerzialisierung Genanalyse |
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