Clay-based pharmaceutical formulations and drug delivery systems:
This book includes recent advances in the use of clays in the design of medicinal products and medicinal devices. The pharmaceutical applications of nanoclays are far ranging, because of their distinct advantages: they are versatile (possess a wide range of mechanical, chemical and physical properti...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Basel
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Online-Zugang: | Volltext Volltext |
| Zusammenfassung: | This book includes recent advances in the use of clays in the design of medicinal products and medicinal devices. The pharmaceutical applications of nanoclays are far ranging, because of their distinct advantages: they are versatile (possess a wide range of mechanical, chemical and physical properties) and available at reasonable costs. Some special clays (mainly kaolinite, halloysite, montmorillonite, saponite, hectorite, palygorskite and sepiolite), as well as semi-synthetic (organoclays) or synthetic (double layer hydroxides) derivatives, are very useful materials for modulating drug delivery. In the last decade, several actives have been loaded onto nanoclays and similar inorganic excipients to increase solubility, improve stability, reduce toxicity, and enhance bioavailability, with a consequent increase in therapeutic response. Polymer/clay nanocomposites with synergic properties have been developed, showing improved mechanical properties with respect to the pristine polymer matrices and allowing modified release of loaded actives. Moreover, nanoclays have very recently demonstrated positive effects on the proliferation and migration of fibroblasts. The development of clay-based medicinal products and medicinal devices requires experience in the fields of both clay structure and properties and pharmaceutical technology design. |
| Beschreibung: | 1 Online-Ressource |
| ISBN: | 9783036501871 |
| DOI: | 10.3390/books978-3-0365-0187-1 |
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| spelling | Clay-based pharmaceutical formulations and drug delivery systems edited by: César Viseras Basel MDPI - Multidisciplinary Digital Publishing Institute 2021 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier This book includes recent advances in the use of clays in the design of medicinal products and medicinal devices. The pharmaceutical applications of nanoclays are far ranging, because of their distinct advantages: they are versatile (possess a wide range of mechanical, chemical and physical properties) and available at reasonable costs. Some special clays (mainly kaolinite, halloysite, montmorillonite, saponite, hectorite, palygorskite and sepiolite), as well as semi-synthetic (organoclays) or synthetic (double layer hydroxides) derivatives, are very useful materials for modulating drug delivery. In the last decade, several actives have been loaded onto nanoclays and similar inorganic excipients to increase solubility, improve stability, reduce toxicity, and enhance bioavailability, with a consequent increase in therapeutic response. Polymer/clay nanocomposites with synergic properties have been developed, showing improved mechanical properties with respect to the pristine polymer matrices and allowing modified release of loaded actives. Moreover, nanoclays have very recently demonstrated positive effects on the proliferation and migration of fibroblasts. The development of clay-based medicinal products and medicinal devices requires experience in the fields of both clay structure and properties and pharmaceutical technology design. Therapeutisches System (DE-588)4267580-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Therapeutisches System (DE-588)4267580-7 s DE-604 Viseras, César edt Erscheint auch als Druck-Ausgabe, Hardcover 978-3-0365-0186-4 https://doi.org/10.3390/books978-3-0365-0187-1 Verlag kostenfrei Volltext https://directory.doabooks.org/handle/20.500.12854/68311 Verlag kostenfrei Volltext |
| spellingShingle | Clay-based pharmaceutical formulations and drug delivery systems Therapeutisches System (DE-588)4267580-7 gnd |
| subject_GND | (DE-588)4267580-7 (DE-588)4143413-4 |
| title | Clay-based pharmaceutical formulations and drug delivery systems |
| title_auth | Clay-based pharmaceutical formulations and drug delivery systems |
| title_exact_search | Clay-based pharmaceutical formulations and drug delivery systems |
| title_exact_search_txtP | Clay-based pharmaceutical formulations and drug delivery systems |
| title_full | Clay-based pharmaceutical formulations and drug delivery systems edited by: César Viseras |
| title_fullStr | Clay-based pharmaceutical formulations and drug delivery systems edited by: César Viseras |
| title_full_unstemmed | Clay-based pharmaceutical formulations and drug delivery systems edited by: César Viseras |
| title_short | Clay-based pharmaceutical formulations and drug delivery systems |
| title_sort | clay based pharmaceutical formulations and drug delivery systems |
| topic | Therapeutisches System (DE-588)4267580-7 gnd |
| topic_facet | Therapeutisches System Aufsatzsammlung |
| url | https://doi.org/10.3390/books978-3-0365-0187-1 https://directory.doabooks.org/handle/20.500.12854/68311 |
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