NMR with biological macromolecules in solution: a selection of papers published from 1996 to 2020 by Kurt Wüthrich
"The book provides insights into the research of the Kurt Wüthrich laboratories from 1996-2020. During this time period, the technique of nuclear magnetic resonance (NMR) spectroscopy in solution went through several breakthroughs, while maturing into a standard method of structural biology. W...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Singapore
World Scientific
2021
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| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | "The book provides insights into the research of the Kurt Wüthrich laboratories from 1996-2020. During this time period, the technique of nuclear magnetic resonance (NMR) spectroscopy in solution went through several breakthroughs, while maturing into a standard method of structural biology. With the introduction of TROSY (transverse relaxation-optimized spectroscopy), the range of accessible molecular sizes was extended about thirty-fold, and efficient protein structure determination resulted from the demands of the structural genomics initiative. Applications in fundamental biology and biomedicine include studies of prion proteins and prion diseases (TSEs), the SARS-Corona virus proteome, trans-membrane signalling by G protein-coupled receptors (GPCRs), and signal transfer by pheromones. Key publications from the Kurt Wüthrich laboratories are placed in perspective, providing insights into new aspects of NMR spectroscopy in structural biology. In addition to methods development, this includes applications in diverse areas of biological research, such as prion proteins and their role in transmissible spongiform encephalopathies (TSEs), trans-membrane signal transfer by G protein-coupled receptors (GPCRs), structural characterization of the SARS-Corona virus proteome, metabolic-flux profiling in bacterial cultures, and signal transfers by pheromones."-- |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | 1 Online-Ressource (264 Seiten) |
| ISBN: | 9789811235795 9811235791 |
| DOI: | 10.1142/12245 |
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Datensatz im Suchindex
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| author_facet | Wüthrich, Kurt |
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| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
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| dewey-tens | 610 - Medicine and health |
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| doi_str_mv | 10.1142/12245 |
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| id | DE-604.BV047457952 |
| illustrated | Not Illustrated |
| index_date | 2024-07-03T18:05:19Z |
| indexdate | 2024-07-10T09:12:41Z |
| institution | BVB |
| isbn | 9789811235795 9811235791 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-032859787 |
| oclc_num | 1268181557 |
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| psigel | ZDB-124-WOP |
| publishDate | 2021 |
| publishDateSearch | 2021 |
| publishDateSort | 2021 |
| publisher | World Scientific |
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| spelling | Wüthrich, Kurt Verfasser aut NMR with biological macromolecules in solution a selection of papers published from 1996 to 2020 by Kurt Wüthrich edited by Kurt Wüthrich Singapore World Scientific 2021 1 Online-Ressource (264 Seiten) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index "The book provides insights into the research of the Kurt Wüthrich laboratories from 1996-2020. During this time period, the technique of nuclear magnetic resonance (NMR) spectroscopy in solution went through several breakthroughs, while maturing into a standard method of structural biology. With the introduction of TROSY (transverse relaxation-optimized spectroscopy), the range of accessible molecular sizes was extended about thirty-fold, and efficient protein structure determination resulted from the demands of the structural genomics initiative. Applications in fundamental biology and biomedicine include studies of prion proteins and prion diseases (TSEs), the SARS-Corona virus proteome, trans-membrane signalling by G protein-coupled receptors (GPCRs), and signal transfer by pheromones. Key publications from the Kurt Wüthrich laboratories are placed in perspective, providing insights into new aspects of NMR spectroscopy in structural biology. In addition to methods development, this includes applications in diverse areas of biological research, such as prion proteins and their role in transmissible spongiform encephalopathies (TSEs), trans-membrane signal transfer by G protein-coupled receptors (GPCRs), structural characterization of the SARS-Corona virus proteome, metabolic-flux profiling in bacterial cultures, and signal transfers by pheromones."-- Nuclear magnetic resonance spectroscopy Macromolecules Biomolecules Electronic books Erscheint auch als Druck-Ausgabe 9789811235788 Erscheint auch als Druck-Ausgabe 9811235783 Erscheint auch als Druck-Ausgabe 9789811239137 Erscheint auch als Druck-Ausgabe 9811239134 https://doi.org/10.1142/12245 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Wüthrich, Kurt NMR with biological macromolecules in solution a selection of papers published from 1996 to 2020 by Kurt Wüthrich Nuclear magnetic resonance spectroscopy Macromolecules Biomolecules |
| title | NMR with biological macromolecules in solution a selection of papers published from 1996 to 2020 by Kurt Wüthrich |
| title_auth | NMR with biological macromolecules in solution a selection of papers published from 1996 to 2020 by Kurt Wüthrich |
| title_exact_search | NMR with biological macromolecules in solution a selection of papers published from 1996 to 2020 by Kurt Wüthrich |
| title_exact_search_txtP | NMR with biological macromolecules in solution a selection of papers published from 1996 to 2020 by Kurt Wüthrich |
| title_full | NMR with biological macromolecules in solution a selection of papers published from 1996 to 2020 by Kurt Wüthrich edited by Kurt Wüthrich |
| title_fullStr | NMR with biological macromolecules in solution a selection of papers published from 1996 to 2020 by Kurt Wüthrich edited by Kurt Wüthrich |
| title_full_unstemmed | NMR with biological macromolecules in solution a selection of papers published from 1996 to 2020 by Kurt Wüthrich edited by Kurt Wüthrich |
| title_short | NMR with biological macromolecules in solution |
| title_sort | nmr with biological macromolecules in solution a selection of papers published from 1996 to 2020 by kurt wuthrich |
| title_sub | a selection of papers published from 1996 to 2020 by Kurt Wüthrich |
| topic | Nuclear magnetic resonance spectroscopy Macromolecules Biomolecules |
| topic_facet | Nuclear magnetic resonance spectroscopy Macromolecules Biomolecules |
| url | https://doi.org/10.1142/12245 |
| work_keys_str_mv | AT wuthrichkurt nmrwithbiologicalmacromoleculesinsolutionaselectionofpaperspublishedfrom1996to2020bykurtwuthrich |