Comprehensive Natural Products III:
9780081026915_WEB01 -- Comprehensive Natural Products III Chemistry and Biology -- Copyright -- Contents of Volume 1 -- Editors-in-Chief -- Volume Editors -- List of Contributors for Volume 1 -- Volume Contents -- Preface -- 1.01. Overview and Introduction -- 1.02. Bacterial Type IPolyketide Synthas...
Gespeichert in:
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| Weitere Verfasser: | |
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
San Diego
Elsevier
2020
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| Ausgabe: | 3rd ed |
| Schlagworte: | |
| Zusammenfassung: | 9780081026915_WEB01 -- Comprehensive Natural Products III Chemistry and Biology -- Copyright -- Contents of Volume 1 -- Editors-in-Chief -- Volume Editors -- List of Contributors for Volume 1 -- Volume Contents -- Preface -- 1.01. Overview and Introduction -- 1.02. Bacterial Type IPolyketide Synthases -- 1.02.1. Preface -- 1.02.2. Introduction to the Complex Polyketides -- 1.02.3. Modular Polyketide Synthases and Relationship to Fatty Acid Synthases -- 1.02.3.1. Modular PKSs: Variations on aTheme -- 1.02.3.1.1. Trans-ATPKSs -- 1.02.3.1.2. Modular PKS modules which iterate -- 1.02.3.1.3. PKS-NRPS and other hybrids -- 1.02.4. Enzymology and Structural Biology of Modular PKS Domains -- 1.02.4.1. Acyl Transferases -- 1.02.4.2. Ketosynthases -- 1.02.4.2.1. A β-branch forming KS domain -- 1.02.4.3. Ketoreductases -- 1.02.4.3.1. α-Specific ketoreductase domains -- 1.02.4.4. Dehydratases -- 1.02.4.4.1. DH variants -- 1.02.4.5. Enoyl Reductases -- 1.02.4.5.1. ER catalyzing cyclopropanation -- 1.02.4.6. C-Methyl Transferases -- 1.02.4.7. Thioesterases -- 1.02.4.7.1. VariantTEs -- 1.02.4.8. Acyl Carrier Proteins -- 1.02.4.9. Domains Catalyzing Unusual Chemistries -- 1.02.5. The 3D Architectures of PKS Modules/Subunits -- 1.02.5.1. Structural Insights Into Intact PKS Modules -- 1.02.5.2. Modular PKS Structural Biology: FutureGoals -- 1.02.6. Protein-Protein Interactions in ModularPKSs -- 1.02.6.1. ACP-Centered Domain-Domain Interactions -- 1.02.6.2. Interactions Between Modules/Subunits -- 1.02.6.2.1. Intramolecular intermodular interactions -- 1.02.6.2.2. Intermolecular intermodular interactions (or docking) -- 1.02.7. Programming of Modular Polyketide Biosynthesis -- 1.02.8. Modular PKS Synthetic Biology -- 1.02.9. Conclusions and Future Perspectives -- Acknowledgment -- References -- 1.03. Structural Biology of Tailoring Domains in Polyketide Synthases |
| Beschreibung: | Description based on publisher supplied metadata and other sources |
| Beschreibung: | 1 online resource (4252 pages) |
| ISBN: | 9780081026915 |
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| spelling | Begley, Tadhg P. Verfasser (DE-588)1089472560 aut Comprehensive Natural Products III 3rd ed San Diego Elsevier 2020 1 online resource (4252 pages) txt rdacontent c rdamedia cr rdacarrier Description based on publisher supplied metadata and other sources 9780081026915_WEB01 -- Comprehensive Natural Products III Chemistry and Biology -- Copyright -- Contents of Volume 1 -- Editors-in-Chief -- Volume Editors -- List of Contributors for Volume 1 -- Volume Contents -- Preface -- 1.01. Overview and Introduction -- 1.02. Bacterial Type IPolyketide Synthases -- 1.02.1. Preface -- 1.02.2. Introduction to the Complex Polyketides -- 1.02.3. Modular Polyketide Synthases and Relationship to Fatty Acid Synthases -- 1.02.3.1. Modular PKSs: Variations on aTheme -- 1.02.3.1.1. Trans-ATPKSs -- 1.02.3.1.2. Modular PKS modules which iterate -- 1.02.3.1.3. PKS-NRPS and other hybrids -- 1.02.4. Enzymology and Structural Biology of Modular PKS Domains -- 1.02.4.1. Acyl Transferases -- 1.02.4.2. Ketosynthases -- 1.02.4.2.1. A β-branch forming KS domain -- 1.02.4.3. Ketoreductases -- 1.02.4.3.1. α-Specific ketoreductase domains -- 1.02.4.4. Dehydratases -- 1.02.4.4.1. DH variants -- 1.02.4.5. Enoyl Reductases -- 1.02.4.5.1. ER catalyzing cyclopropanation -- 1.02.4.6. C-Methyl Transferases -- 1.02.4.7. Thioesterases -- 1.02.4.7.1. VariantTEs -- 1.02.4.8. Acyl Carrier Proteins -- 1.02.4.9. Domains Catalyzing Unusual Chemistries -- 1.02.5. The 3D Architectures of PKS Modules/Subunits -- 1.02.5.1. Structural Insights Into Intact PKS Modules -- 1.02.5.2. Modular PKS Structural Biology: FutureGoals -- 1.02.6. Protein-Protein Interactions in ModularPKSs -- 1.02.6.1. ACP-Centered Domain-Domain Interactions -- 1.02.6.2. Interactions Between Modules/Subunits -- 1.02.6.2.1. Intramolecular intermodular interactions -- 1.02.6.2.2. Intermolecular intermodular interactions (or docking) -- 1.02.7. Programming of Modular Polyketide Biosynthesis -- 1.02.8. Modular PKS Synthetic Biology -- 1.02.9. Conclusions and Future Perspectives -- Acknowledgment -- References -- 1.03. Structural Biology of Tailoring Domains in Polyketide Synthases Electronic books Liu, Hung-Wen ctb |
| spellingShingle | Begley, Tadhg P. Comprehensive Natural Products III |
| title | Comprehensive Natural Products III |
| title_auth | Comprehensive Natural Products III |
| title_exact_search | Comprehensive Natural Products III |
| title_exact_search_txtP | Comprehensive Natural Products III |
| title_full | Comprehensive Natural Products III |
| title_fullStr | Comprehensive Natural Products III |
| title_full_unstemmed | Comprehensive Natural Products III |
| title_short | Comprehensive Natural Products III |
| title_sort | comprehensive natural products iii |
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