Structure and function of membrane proteins:
This book examines detailed experimental and computational approaches for the analysis of many aspects vital to the understanding of membrane protein structure and function. Readers will receive guidance on the selection and use of methods for over-expression and purification, tools to characterize...
Gespeichert in:
Weitere Verfasser: | , |
---|---|
Format: | Buch |
Sprache: | English |
Veröffentlicht: |
New York, NY
Humana Press
[2021]
|
Schriftenreihe: | Methods in molecular biology
2302 |
Schlagworte: | |
Zusammenfassung: | This book examines detailed experimental and computational approaches for the analysis of many aspects vital to the understanding of membrane protein structure and function. Readers will receive guidance on the selection and use of methods for over-expression and purification, tools to characterize membrane proteins within different phospholipid bilayers, direction on functional studies, and approaches to determine the structures of membrane proteins. Detailed experimental steps for specific membrane proteins with critical notes allow the protocols to be modified to different systems. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of practical information and implementation advice that leads to excellent, reproducible results. Authoritative and up-to-date, Structure and Function Studies of Membrane Proteins serves as an ideal guide for biologists, biochemists, and biophysicists striving to further understand these essential proteins and their many biological roles |
Beschreibung: | 1. Expression and Purification of Human Mitochondrial Intramembrane Protease PARL; Elena Arutyunova, Laine Lysyk, Melissa Morrison, Cory Brooks, and M. Joanne Lemieux; ; 2. Reconstitution of Detergent-Solubilized Membrane Proteins into Proteoliposomes and Nanodiscs for Functional and Structural Studies; Kerry M. Strickland, Kasahun Neselu, Arshay J. Grant, Carolann L. Espy, Nael A. McCarty, and Ingeborg Schmidt-Krey; ; 3. Biochemical Characterization of GPCR–G Protein Complex Formation; Filip Pamula and Ching-Ju Tsai; ; 4. Electrophysiological Approaches for the Study of Ion Channel Function; Guiying Cui, Kirsten A. Cottrill, and Nael A. McCarty; ; 5. Isothermal Titration Calorimetry of Membrane Proteins; Han N. Vu, Alan J. Situ, and Tobias S. Ulmer; ; 6. Atomic Force Microscopy Reveals Membrane Protein Activity at the Single Molecule Level; Kanokporn Chattrakun, Katherine G. Schaefer, Lucas S. - Chandler, Brendan P. Marsh, and Gavin M. King; ; 7. Structure Determination of Membrane Proteins Using X-Ray Crystallography; Evan Billings, Karl Lundquist, Claire Overly, Karthik Srinivasan, and Nicholas Noinaj; ; 8. Studying Membrane Protein Structures by MicroED; Michael W. Martynowycz and Tamir Gonen; ; 9. Single-Particle Cryo-EM of Membrane Proteins; Dovile Januliene and Arne Moeller; ; 10. Helical Membrane Protein Crystallization in the New Era of Electron Cryo-Microscopy; Mary D. Hernando, Joseph O. Primeau, and Howard S. Young; ; 11. NMR Spectroscopic Studies of Ion Channels in Lipid Bilayers: Sample Preparation Strategies Exemplified by the Voltage Dependent Anion Channel; Robert Silvers and Matthew Eddy; ; 12. Preparation of a Deuterated Membrane Protein for Small-Angle Neutron Scattering; Yuqi Wu, Kevin L. Weiss, and Raquel L. Lieberman; ; 13. - Preparing Membrane Proteins for Simulation Using CHARMM-GUI; Yupeng Li, Jinchan Liu, and James C. Gumbart; ; 14. Coarse-Grained Molecular Dynamics Simulations of Membrane Proteins: A Practical Guide; William Glass, Jonathan W. Essex, Franca Fraternali, James Gebbie-Rayet, Irene Marzuoli, Marley L. Samways, Philip C. Biggin, and Syma Khalid; ; 15. Continuous Constant pH Molecular Dynamics Simulations of Transmembrane Proteins; Yandong Huang, Jack A. Henderson, and Jana Shen; ; 16. Molecular Dynamics-Based Thermodynamic and Kinetic Characterization of Membrane Protein Conformational Transitions; Dylan Ogden and Mahmoud Moradi; ; 17. Concepts, Practices, and Interactive Tutorial for Allosteric Network Analysis of Molecular Dynamics Simulations; Wesley M. Botello-Smith and Yun Lyna Luo; ; 18. - Large Scale Molecular Dynamics Simulations of Cellular Compartments; Eric Wilson, John Vant, Jacob Layton, Ryan Boyd, Hyungro Lee, Matteo Turilli, Benjamín Hernández, Sean Wilkinson, Shantenu Jha, Chitrak Gupta, Daipayan Sarkar, and Abhishek Singharoy |
Beschreibung: | xii, 358 Seiten Illustrationen, Diagramme 885 grams |
ISBN: | 9781071613931 |
Internformat
MARC
LEADER | 00000nam a2200000 cb4500 | ||
---|---|---|---|
001 | BV047300650 | ||
003 | DE-604 | ||
005 | 20220308 | ||
007 | t | ||
008 | 210527s2021 a||| |||| 00||| eng d | ||
020 | |a 9781071613931 |c hbk |9 978-1-0716-1393-1 | ||
024 | 3 | |a 9781071613931 | |
035 | |a (OCoLC)1256436712 | ||
035 | |a (DE-599)BVBBV047300650 | ||
040 | |a DE-604 |b ger |e rda | ||
041 | 0 | |a eng | |
049 | |a DE-29T |a DE-11 |a DE-19 | ||
084 | |a WE 5160 |0 (DE-625)148299: |2 rvk | ||
084 | |a WC 4170 |0 (DE-625)148093: |2 rvk | ||
245 | 1 | 0 | |a Structure and function of membrane proteins |c edited by Ingeborg Schmidt-Krey, James C. Gumbart |
264 | 1 | |a New York, NY |b Humana Press |c [2021] | |
300 | |a xii, 358 Seiten |b Illustrationen, Diagramme |c 885 grams | ||
336 | |b txt |2 rdacontent | ||
337 | |b n |2 rdamedia | ||
338 | |b nc |2 rdacarrier | ||
490 | 1 | |a Methods in molecular biology |v 2302 | |
490 | 0 | |a Springer protocols | |
500 | |a 1. Expression and Purification of Human Mitochondrial Intramembrane Protease PARL; Elena Arutyunova, Laine Lysyk, Melissa Morrison, Cory Brooks, and M. Joanne Lemieux; ; 2. Reconstitution of Detergent-Solubilized Membrane Proteins into Proteoliposomes and Nanodiscs for Functional and Structural Studies; Kerry M. Strickland, Kasahun Neselu, Arshay J. Grant, Carolann L. Espy, Nael A. McCarty, and Ingeborg Schmidt-Krey; ; 3. Biochemical Characterization of GPCR–G Protein Complex Formation; Filip Pamula and Ching-Ju Tsai; ; 4. Electrophysiological Approaches for the Study of Ion Channel Function; Guiying Cui, Kirsten A. Cottrill, and Nael A. McCarty; ; 5. Isothermal Titration Calorimetry of Membrane Proteins; Han N. Vu, Alan J. Situ, and Tobias S. Ulmer; ; 6. Atomic Force Microscopy Reveals Membrane Protein Activity at the Single Molecule Level; Kanokporn Chattrakun, Katherine G. Schaefer, Lucas S. | ||
500 | |a - Chandler, Brendan P. Marsh, and Gavin M. King; ; 7. Structure Determination of Membrane Proteins Using X-Ray Crystallography; Evan Billings, Karl Lundquist, Claire Overly, Karthik Srinivasan, and Nicholas Noinaj; ; 8. Studying Membrane Protein Structures by MicroED; Michael W. Martynowycz and Tamir Gonen; ; 9. Single-Particle Cryo-EM of Membrane Proteins; Dovile Januliene and Arne Moeller; ; 10. Helical Membrane Protein Crystallization in the New Era of Electron Cryo-Microscopy; Mary D. Hernando, Joseph O. Primeau, and Howard S. Young; ; 11. NMR Spectroscopic Studies of Ion Channels in Lipid Bilayers: Sample Preparation Strategies Exemplified by the Voltage Dependent Anion Channel; Robert Silvers and Matthew Eddy; ; 12. Preparation of a Deuterated Membrane Protein for Small-Angle Neutron Scattering; Yuqi Wu, Kevin L. Weiss, and Raquel L. Lieberman; ; 13. | ||
500 | |a - Preparing Membrane Proteins for Simulation Using CHARMM-GUI; Yupeng Li, Jinchan Liu, and James C. Gumbart; ; 14. Coarse-Grained Molecular Dynamics Simulations of Membrane Proteins: A Practical Guide; William Glass, Jonathan W. Essex, Franca Fraternali, James Gebbie-Rayet, Irene Marzuoli, Marley L. Samways, Philip C. Biggin, and Syma Khalid; ; 15. Continuous Constant pH Molecular Dynamics Simulations of Transmembrane Proteins; Yandong Huang, Jack A. Henderson, and Jana Shen; ; 16. Molecular Dynamics-Based Thermodynamic and Kinetic Characterization of Membrane Protein Conformational Transitions; Dylan Ogden and Mahmoud Moradi; ; 17. Concepts, Practices, and Interactive Tutorial for Allosteric Network Analysis of Molecular Dynamics Simulations; Wesley M. Botello-Smith and Yun Lyna Luo; ; 18. | ||
500 | |a - Large Scale Molecular Dynamics Simulations of Cellular Compartments; Eric Wilson, John Vant, Jacob Layton, Ryan Boyd, Hyungro Lee, Matteo Turilli, Benjamín Hernández, Sean Wilkinson, Shantenu Jha, Chitrak Gupta, Daipayan Sarkar, and Abhishek Singharoy | ||
520 | |a This book examines detailed experimental and computational approaches for the analysis of many aspects vital to the understanding of membrane protein structure and function. Readers will receive guidance on the selection and use of methods for over-expression and purification, tools to characterize membrane proteins within different phospholipid bilayers, direction on functional studies, and approaches to determine the structures of membrane proteins. Detailed experimental steps for specific membrane proteins with critical notes allow the protocols to be modified to different systems. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of practical information and implementation advice that leads to excellent, reproducible results. Authoritative and up-to-date, Structure and Function Studies of Membrane Proteins serves as an ideal guide for biologists, biochemists, and biophysicists striving to further understand these essential proteins and their many biological roles | ||
650 | 4 | |a bisacsh | |
650 | 4 | |a Cell biology | |
650 | 4 | |a Cell membranes | |
650 | 4 | |a Proteins | |
650 | 4 | |a Life sciences | |
650 | 0 | 7 | |a Strukturanalyse |0 (DE-588)4183787-3 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Membranproteine |0 (DE-588)4130026-9 |2 gnd |9 rswk-swf |
653 | |a Mikrobiologie | ||
655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
689 | 0 | 0 | |a Membranproteine |0 (DE-588)4130026-9 |D s |
689 | 0 | 1 | |a Strukturanalyse |0 (DE-588)4183787-3 |D s |
689 | 0 | |5 DE-604 | |
700 | 1 | |a Schmidt-Krey, Ingeborg |0 (DE-588)1247188345 |4 edt | |
700 | 1 | |a Gumbart, James C. |0 (DE-588)1247189007 |4 edt | |
776 | 0 | 8 | |i Erscheint auch als |n Online-Ausgabe |z 978-1-0716-1394-8 |
830 | 0 | |a Methods in molecular biology |v 2302 |w (DE-604)BV035362695 |9 2302 | |
999 | |a oai:aleph.bib-bvb.de:BVB01-032703818 |
Datensatz im Suchindex
_version_ | 1804182481113448448 |
---|---|
adam_txt | |
any_adam_object | |
any_adam_object_boolean | |
author2 | Schmidt-Krey, Ingeborg Gumbart, James C. |
author2_role | edt edt |
author2_variant | i s k isk j c g jc jcg |
author_GND | (DE-588)1247188345 (DE-588)1247189007 |
author_facet | Schmidt-Krey, Ingeborg Gumbart, James C. |
building | Verbundindex |
bvnumber | BV047300650 |
classification_rvk | WE 5160 WC 4170 |
ctrlnum | (OCoLC)1256436712 (DE-599)BVBBV047300650 |
discipline | Biologie |
discipline_str_mv | Biologie |
format | Book |
fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>05695nam a2200553 cb4500</leader><controlfield tag="001">BV047300650</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20220308 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">210527s2021 a||| |||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781071613931</subfield><subfield code="c">hbk</subfield><subfield code="9">978-1-0716-1393-1</subfield></datafield><datafield tag="024" ind1="3" ind2=" "><subfield code="a">9781071613931</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1256436712</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV047300650</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-29T</subfield><subfield code="a">DE-11</subfield><subfield code="a">DE-19</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WE 5160</subfield><subfield code="0">(DE-625)148299:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WC 4170</subfield><subfield code="0">(DE-625)148093:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Structure and function of membrane proteins</subfield><subfield code="c">edited by Ingeborg Schmidt-Krey, James C. Gumbart</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">New York, NY</subfield><subfield code="b">Humana Press</subfield><subfield code="c">[2021]</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">xii, 358 Seiten</subfield><subfield code="b">Illustrationen, Diagramme</subfield><subfield code="c">885 grams</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="1" ind2=" "><subfield code="a">Methods in molecular biology</subfield><subfield code="v">2302</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Springer protocols</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">1. Expression and Purification of Human Mitochondrial Intramembrane Protease PARL; Elena Arutyunova, Laine Lysyk, Melissa Morrison, Cory Brooks, and M. Joanne Lemieux; ; 2. Reconstitution of Detergent-Solubilized Membrane Proteins into Proteoliposomes and Nanodiscs for Functional and Structural Studies; Kerry M. Strickland, Kasahun Neselu, Arshay J. Grant, Carolann L. Espy, Nael A. McCarty, and Ingeborg Schmidt-Krey; ; 3. Biochemical Characterization of GPCR–G Protein Complex Formation; Filip Pamula and Ching-Ju Tsai; ; 4. Electrophysiological Approaches for the Study of Ion Channel Function; Guiying Cui, Kirsten A. Cottrill, and Nael A. McCarty; ; 5. Isothermal Titration Calorimetry of Membrane Proteins; Han N. Vu, Alan J. Situ, and Tobias S. Ulmer; ; 6. Atomic Force Microscopy Reveals Membrane Protein Activity at the Single Molecule Level; Kanokporn Chattrakun, Katherine G. Schaefer, Lucas S. </subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a"> - Chandler, Brendan P. Marsh, and Gavin M. King; ; 7. Structure Determination of Membrane Proteins Using X-Ray Crystallography; Evan Billings, Karl Lundquist, Claire Overly, Karthik Srinivasan, and Nicholas Noinaj; ; 8. Studying Membrane Protein Structures by MicroED; Michael W. Martynowycz and Tamir Gonen; ; 9. Single-Particle Cryo-EM of Membrane Proteins; Dovile Januliene and Arne Moeller; ; 10. Helical Membrane Protein Crystallization in the New Era of Electron Cryo-Microscopy; Mary D. Hernando, Joseph O. Primeau, and Howard S. Young; ; 11. NMR Spectroscopic Studies of Ion Channels in Lipid Bilayers: Sample Preparation Strategies Exemplified by the Voltage Dependent Anion Channel; Robert Silvers and Matthew Eddy; ; 12. Preparation of a Deuterated Membrane Protein for Small-Angle Neutron Scattering; Yuqi Wu, Kevin L. Weiss, and Raquel L. Lieberman; ; 13. </subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a"> - Preparing Membrane Proteins for Simulation Using CHARMM-GUI; Yupeng Li, Jinchan Liu, and James C. Gumbart; ; 14. Coarse-Grained Molecular Dynamics Simulations of Membrane Proteins: A Practical Guide; William Glass, Jonathan W. Essex, Franca Fraternali, James Gebbie-Rayet, Irene Marzuoli, Marley L. Samways, Philip C. Biggin, and Syma Khalid; ; 15. Continuous Constant pH Molecular Dynamics Simulations of Transmembrane Proteins; Yandong Huang, Jack A. Henderson, and Jana Shen; ; 16. Molecular Dynamics-Based Thermodynamic and Kinetic Characterization of Membrane Protein Conformational Transitions; Dylan Ogden and Mahmoud Moradi; ; 17. Concepts, Practices, and Interactive Tutorial for Allosteric Network Analysis of Molecular Dynamics Simulations; Wesley M. Botello-Smith and Yun Lyna Luo; ; 18. </subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a"> - Large Scale Molecular Dynamics Simulations of Cellular Compartments; Eric Wilson, John Vant, Jacob Layton, Ryan Boyd, Hyungro Lee, Matteo Turilli, Benjamín Hernández, Sean Wilkinson, Shantenu Jha, Chitrak Gupta, Daipayan Sarkar, and Abhishek Singharoy</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">This book examines detailed experimental and computational approaches for the analysis of many aspects vital to the understanding of membrane protein structure and function. Readers will receive guidance on the selection and use of methods for over-expression and purification, tools to characterize membrane proteins within different phospholipid bilayers, direction on functional studies, and approaches to determine the structures of membrane proteins. Detailed experimental steps for specific membrane proteins with critical notes allow the protocols to be modified to different systems. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of practical information and implementation advice that leads to excellent, reproducible results. Authoritative and up-to-date, Structure and Function Studies of Membrane Proteins serves as an ideal guide for biologists, biochemists, and biophysicists striving to further understand these essential proteins and their many biological roles</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cell biology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cell membranes </subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Proteins </subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Life sciences</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Strukturanalyse</subfield><subfield code="0">(DE-588)4183787-3</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Membranproteine</subfield><subfield code="0">(DE-588)4130026-9</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Mikrobiologie</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4143413-4</subfield><subfield code="a">Aufsatzsammlung</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Membranproteine</subfield><subfield code="0">(DE-588)4130026-9</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Strukturanalyse</subfield><subfield code="0">(DE-588)4183787-3</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Schmidt-Krey, Ingeborg</subfield><subfield code="0">(DE-588)1247188345</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Gumbart, James C.</subfield><subfield code="0">(DE-588)1247189007</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Online-Ausgabe</subfield><subfield code="z">978-1-0716-1394-8</subfield></datafield><datafield tag="830" ind1=" " ind2="0"><subfield code="a">Methods in molecular biology</subfield><subfield code="v">2302</subfield><subfield code="w">(DE-604)BV035362695</subfield><subfield code="9">2302</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-032703818</subfield></datafield></record></collection> |
genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
genre_facet | Aufsatzsammlung |
id | DE-604.BV047300650 |
illustrated | Illustrated |
index_date | 2024-07-03T17:23:21Z |
indexdate | 2024-07-10T09:08:14Z |
institution | BVB |
isbn | 9781071613931 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-032703818 |
oclc_num | 1256436712 |
open_access_boolean | |
owner | DE-29T DE-11 DE-19 DE-BY-UBM |
owner_facet | DE-29T DE-11 DE-19 DE-BY-UBM |
physical | xii, 358 Seiten Illustrationen, Diagramme 885 grams |
publishDate | 2021 |
publishDateSearch | 2021 |
publishDateSort | 2021 |
publisher | Humana Press |
record_format | marc |
series | Methods in molecular biology |
series2 | Methods in molecular biology Springer protocols |
spelling | Structure and function of membrane proteins edited by Ingeborg Schmidt-Krey, James C. Gumbart New York, NY Humana Press [2021] xii, 358 Seiten Illustrationen, Diagramme 885 grams txt rdacontent n rdamedia nc rdacarrier Methods in molecular biology 2302 Springer protocols 1. Expression and Purification of Human Mitochondrial Intramembrane Protease PARL; Elena Arutyunova, Laine Lysyk, Melissa Morrison, Cory Brooks, and M. Joanne Lemieux; ; 2. Reconstitution of Detergent-Solubilized Membrane Proteins into Proteoliposomes and Nanodiscs for Functional and Structural Studies; Kerry M. Strickland, Kasahun Neselu, Arshay J. Grant, Carolann L. Espy, Nael A. McCarty, and Ingeborg Schmidt-Krey; ; 3. Biochemical Characterization of GPCR–G Protein Complex Formation; Filip Pamula and Ching-Ju Tsai; ; 4. Electrophysiological Approaches for the Study of Ion Channel Function; Guiying Cui, Kirsten A. Cottrill, and Nael A. McCarty; ; 5. Isothermal Titration Calorimetry of Membrane Proteins; Han N. Vu, Alan J. Situ, and Tobias S. Ulmer; ; 6. Atomic Force Microscopy Reveals Membrane Protein Activity at the Single Molecule Level; Kanokporn Chattrakun, Katherine G. Schaefer, Lucas S. - Chandler, Brendan P. Marsh, and Gavin M. King; ; 7. Structure Determination of Membrane Proteins Using X-Ray Crystallography; Evan Billings, Karl Lundquist, Claire Overly, Karthik Srinivasan, and Nicholas Noinaj; ; 8. Studying Membrane Protein Structures by MicroED; Michael W. Martynowycz and Tamir Gonen; ; 9. Single-Particle Cryo-EM of Membrane Proteins; Dovile Januliene and Arne Moeller; ; 10. Helical Membrane Protein Crystallization in the New Era of Electron Cryo-Microscopy; Mary D. Hernando, Joseph O. Primeau, and Howard S. Young; ; 11. NMR Spectroscopic Studies of Ion Channels in Lipid Bilayers: Sample Preparation Strategies Exemplified by the Voltage Dependent Anion Channel; Robert Silvers and Matthew Eddy; ; 12. Preparation of a Deuterated Membrane Protein for Small-Angle Neutron Scattering; Yuqi Wu, Kevin L. Weiss, and Raquel L. Lieberman; ; 13. - Preparing Membrane Proteins for Simulation Using CHARMM-GUI; Yupeng Li, Jinchan Liu, and James C. Gumbart; ; 14. Coarse-Grained Molecular Dynamics Simulations of Membrane Proteins: A Practical Guide; William Glass, Jonathan W. Essex, Franca Fraternali, James Gebbie-Rayet, Irene Marzuoli, Marley L. Samways, Philip C. Biggin, and Syma Khalid; ; 15. Continuous Constant pH Molecular Dynamics Simulations of Transmembrane Proteins; Yandong Huang, Jack A. Henderson, and Jana Shen; ; 16. Molecular Dynamics-Based Thermodynamic and Kinetic Characterization of Membrane Protein Conformational Transitions; Dylan Ogden and Mahmoud Moradi; ; 17. Concepts, Practices, and Interactive Tutorial for Allosteric Network Analysis of Molecular Dynamics Simulations; Wesley M. Botello-Smith and Yun Lyna Luo; ; 18. - Large Scale Molecular Dynamics Simulations of Cellular Compartments; Eric Wilson, John Vant, Jacob Layton, Ryan Boyd, Hyungro Lee, Matteo Turilli, Benjamín Hernández, Sean Wilkinson, Shantenu Jha, Chitrak Gupta, Daipayan Sarkar, and Abhishek Singharoy This book examines detailed experimental and computational approaches for the analysis of many aspects vital to the understanding of membrane protein structure and function. Readers will receive guidance on the selection and use of methods for over-expression and purification, tools to characterize membrane proteins within different phospholipid bilayers, direction on functional studies, and approaches to determine the structures of membrane proteins. Detailed experimental steps for specific membrane proteins with critical notes allow the protocols to be modified to different systems. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of practical information and implementation advice that leads to excellent, reproducible results. Authoritative and up-to-date, Structure and Function Studies of Membrane Proteins serves as an ideal guide for biologists, biochemists, and biophysicists striving to further understand these essential proteins and their many biological roles bisacsh Cell biology Cell membranes Proteins Life sciences Strukturanalyse (DE-588)4183787-3 gnd rswk-swf Membranproteine (DE-588)4130026-9 gnd rswk-swf Mikrobiologie (DE-588)4143413-4 Aufsatzsammlung gnd-content Membranproteine (DE-588)4130026-9 s Strukturanalyse (DE-588)4183787-3 s DE-604 Schmidt-Krey, Ingeborg (DE-588)1247188345 edt Gumbart, James C. (DE-588)1247189007 edt Erscheint auch als Online-Ausgabe 978-1-0716-1394-8 Methods in molecular biology 2302 (DE-604)BV035362695 2302 |
spellingShingle | Structure and function of membrane proteins Methods in molecular biology bisacsh Cell biology Cell membranes Proteins Life sciences Strukturanalyse (DE-588)4183787-3 gnd Membranproteine (DE-588)4130026-9 gnd |
subject_GND | (DE-588)4183787-3 (DE-588)4130026-9 (DE-588)4143413-4 |
title | Structure and function of membrane proteins |
title_auth | Structure and function of membrane proteins |
title_exact_search | Structure and function of membrane proteins |
title_exact_search_txtP | Structure and function of membrane proteins |
title_full | Structure and function of membrane proteins edited by Ingeborg Schmidt-Krey, James C. Gumbart |
title_fullStr | Structure and function of membrane proteins edited by Ingeborg Schmidt-Krey, James C. Gumbart |
title_full_unstemmed | Structure and function of membrane proteins edited by Ingeborg Schmidt-Krey, James C. Gumbart |
title_short | Structure and function of membrane proteins |
title_sort | structure and function of membrane proteins |
topic | bisacsh Cell biology Cell membranes Proteins Life sciences Strukturanalyse (DE-588)4183787-3 gnd Membranproteine (DE-588)4130026-9 gnd |
topic_facet | bisacsh Cell biology Cell membranes Proteins Life sciences Strukturanalyse Membranproteine Aufsatzsammlung |
volume_link | (DE-604)BV035362695 |
work_keys_str_mv | AT schmidtkreyingeborg structureandfunctionofmembraneproteins AT gumbartjamesc structureandfunctionofmembraneproteins |