Toxicological Evaluation of Electronic Nicotine Delivery Products:
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
London
Academic Press, an imprint of Elsevier
[2021]
|
| Schlagworte: | |
| Online-Zugang: | TUM01 |
| Beschreibung: | Front Cover -- Toxicological Evaluation of Electronic Nicotine Delivery Products -- Toxicological Evaluation of Electronic Nicotine Delivery Products -- Copyright -- List of Contributors -- Acknowledgments -- Preamble -- Contents -- 1 -- Tobacco Harm Reduction Concepts and Policy Approaches -- 1.1 INTRODUCTION -- 1.2 A CONTINUUM OF HARM -- 1.3 THE ROLE OF HARM REDUCTION -- 1.4 BENEFIT TO THE POPULATION AS A WHOLE -- 1.5 PARAMETERS INFLUENCING HARM REDUCTION POLICIES -- 1.5.1 Product Harm Reduction -- 1.5.2 Product Acceptance and Usage -- 1.5.2.1 Product acceptance -- 1.5.2.2 Awareness 1.5.2.3 Access -- 1.5.2.4 Price -- 1.5.2.5 Sales practices -- 1.6 BALANCING RISK AND BENEFITS UNDER UNCERTAIN CONDITIONS -- 1.6.1 Error Types in Hypothesis Testing -- 1.6.2 Error Preference -- 1.6.3 Reducing (and Accepting) Uncertainty -- 1.7 EXAMPLES OF REGULATORY FRAMEWORKS -- 1.7.1 Regulatory Objectives -- 1.7.2 Ex Ante and Ex Post Regulation -- 1.7.3 Product Bans -- 1.7.4 Product Standards -- 1.7.5 Consumer Access to Information -- 1.8 THE ROLE OF TOBACCO COMPANIES -- 1.9 CONCLUSION -- REFERENCES -- 2 -- Electronic Nicotine Delivery Products -- 2.1 INTRODUCTION 2.2 CONSUMER PRODUCTS THAT DELIVER NICOTINE -- 2.3 THE RATIONALE FOR ENDP DEVELOPMENT -- 2.4 BRIEF HISTORY OF PRODUCT DEVELOPMENT -- 2.4.1 Electronic Cigarettes -- 2.4.2 HTPs -- 2.4.3 Hybrid E-cigarette Products -- 2.5 CONCLUSIONS -- REFERENCES -- 3 -- Scientific Basis for Assessment of Electronic Nicotine Delivery Products -- 3.1 INTRODUCTION -- 3.2 ENDP ASSESSMENT FRAMEWORK -- 3.2.1 First Principle: Epidemiology -- 3.2.1.1 Effects of smoking cessation on disease risk -- 3.2.2 Second Principle: Toxicology -- 3.3 KEY SCIENTIFIC CHALLENGES IN ASSESSMENT OF ENDPS 3.4 SYSTEMS TOXICOLOGY-BASED ASSESSMENT OF ENDPS -- 3.4.1 Predictive Power of Systems Toxicology -- 3.5 A COMPREHENSIVE ASSESSMENT PROGRAM FOR ENDPS -- 3.5.1 Toxicological Assessment Steps -- 3.5.1.1 Step I -- 3.5.1.2 Step II -- 3.5.1.3 Step III -- 3.5.1.4 Step IV -- 3.6 QUALITY CONSIDERATIONS -- 3.6.1 Comparative Studies -- 3.6.2 Exposure and its Verification -- 3.6.2.1 Adequate exposure -- 3.6.2.2 Exposure verification in nonclinical studies -- 3.6.2.3 Exposure verification in clinical studies -- 3.6.3 Independent Peer Review -- 3.7 TRANSPARENT SHARING OF SCIENTIFIC DATA ON ENDP ASSESSMENT |
| Beschreibung: | 1 Online-Ressource |
| ISBN: | 9780128209356 0128209356 |
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| 500 | |a Front Cover -- Toxicological Evaluation of Electronic Nicotine Delivery Products -- Toxicological Evaluation of Electronic Nicotine Delivery Products -- Copyright -- List of Contributors -- Acknowledgments -- Preamble -- Contents -- 1 -- Tobacco Harm Reduction Concepts and Policy Approaches -- 1.1 INTRODUCTION -- 1.2 A CONTINUUM OF HARM -- 1.3 THE ROLE OF HARM REDUCTION -- 1.4 BENEFIT TO THE POPULATION AS A WHOLE -- 1.5 PARAMETERS INFLUENCING HARM REDUCTION POLICIES -- 1.5.1 Product Harm Reduction -- 1.5.2 Product Acceptance and Usage -- 1.5.2.1 Product acceptance -- 1.5.2.2 Awareness | ||
| 500 | |a 1.5.2.3 Access -- 1.5.2.4 Price -- 1.5.2.5 Sales practices -- 1.6 BALANCING RISK AND BENEFITS UNDER UNCERTAIN CONDITIONS -- 1.6.1 Error Types in Hypothesis Testing -- 1.6.2 Error Preference -- 1.6.3 Reducing (and Accepting) Uncertainty -- 1.7 EXAMPLES OF REGULATORY FRAMEWORKS -- 1.7.1 Regulatory Objectives -- 1.7.2 Ex Ante and Ex Post Regulation -- 1.7.3 Product Bans -- 1.7.4 Product Standards -- 1.7.5 Consumer Access to Information -- 1.8 THE ROLE OF TOBACCO COMPANIES -- 1.9 CONCLUSION -- REFERENCES -- 2 -- Electronic Nicotine Delivery Products -- 2.1 INTRODUCTION | ||
| 500 | |a 2.2 CONSUMER PRODUCTS THAT DELIVER NICOTINE -- 2.3 THE RATIONALE FOR ENDP DEVELOPMENT -- 2.4 BRIEF HISTORY OF PRODUCT DEVELOPMENT -- 2.4.1 Electronic Cigarettes -- 2.4.2 HTPs -- 2.4.3 Hybrid E-cigarette Products -- 2.5 CONCLUSIONS -- REFERENCES -- 3 -- Scientific Basis for Assessment of Electronic Nicotine Delivery Products -- 3.1 INTRODUCTION -- 3.2 ENDP ASSESSMENT FRAMEWORK -- 3.2.1 First Principle: Epidemiology -- 3.2.1.1 Effects of smoking cessation on disease risk -- 3.2.2 Second Principle: Toxicology -- 3.3 KEY SCIENTIFIC CHALLENGES IN ASSESSMENT OF ENDPS | ||
| 500 | |a 3.4 SYSTEMS TOXICOLOGY-BASED ASSESSMENT OF ENDPS -- 3.4.1 Predictive Power of Systems Toxicology -- 3.5 A COMPREHENSIVE ASSESSMENT PROGRAM FOR ENDPS -- 3.5.1 Toxicological Assessment Steps -- 3.5.1.1 Step I -- 3.5.1.2 Step II -- 3.5.1.3 Step III -- 3.5.1.4 Step IV -- 3.6 QUALITY CONSIDERATIONS -- 3.6.1 Comparative Studies -- 3.6.2 Exposure and its Verification -- 3.6.2.1 Adequate exposure -- 3.6.2.2 Exposure verification in nonclinical studies -- 3.6.2.3 Exposure verification in clinical studies -- 3.6.3 Independent Peer Review -- 3.7 TRANSPARENT SHARING OF SCIENTIFIC DATA ON ENDP ASSESSMENT | ||
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| spelling | Toxicological Evaluation of Electronic Nicotine Delivery Products edited by Manuel C. Peitsch, Julia Hoeng London Academic Press, an imprint of Elsevier [2021] 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Front Cover -- Toxicological Evaluation of Electronic Nicotine Delivery Products -- Toxicological Evaluation of Electronic Nicotine Delivery Products -- Copyright -- List of Contributors -- Acknowledgments -- Preamble -- Contents -- 1 -- Tobacco Harm Reduction Concepts and Policy Approaches -- 1.1 INTRODUCTION -- 1.2 A CONTINUUM OF HARM -- 1.3 THE ROLE OF HARM REDUCTION -- 1.4 BENEFIT TO THE POPULATION AS A WHOLE -- 1.5 PARAMETERS INFLUENCING HARM REDUCTION POLICIES -- 1.5.1 Product Harm Reduction -- 1.5.2 Product Acceptance and Usage -- 1.5.2.1 Product acceptance -- 1.5.2.2 Awareness 1.5.2.3 Access -- 1.5.2.4 Price -- 1.5.2.5 Sales practices -- 1.6 BALANCING RISK AND BENEFITS UNDER UNCERTAIN CONDITIONS -- 1.6.1 Error Types in Hypothesis Testing -- 1.6.2 Error Preference -- 1.6.3 Reducing (and Accepting) Uncertainty -- 1.7 EXAMPLES OF REGULATORY FRAMEWORKS -- 1.7.1 Regulatory Objectives -- 1.7.2 Ex Ante and Ex Post Regulation -- 1.7.3 Product Bans -- 1.7.4 Product Standards -- 1.7.5 Consumer Access to Information -- 1.8 THE ROLE OF TOBACCO COMPANIES -- 1.9 CONCLUSION -- REFERENCES -- 2 -- Electronic Nicotine Delivery Products -- 2.1 INTRODUCTION 2.2 CONSUMER PRODUCTS THAT DELIVER NICOTINE -- 2.3 THE RATIONALE FOR ENDP DEVELOPMENT -- 2.4 BRIEF HISTORY OF PRODUCT DEVELOPMENT -- 2.4.1 Electronic Cigarettes -- 2.4.2 HTPs -- 2.4.3 Hybrid E-cigarette Products -- 2.5 CONCLUSIONS -- REFERENCES -- 3 -- Scientific Basis for Assessment of Electronic Nicotine Delivery Products -- 3.1 INTRODUCTION -- 3.2 ENDP ASSESSMENT FRAMEWORK -- 3.2.1 First Principle: Epidemiology -- 3.2.1.1 Effects of smoking cessation on disease risk -- 3.2.2 Second Principle: Toxicology -- 3.3 KEY SCIENTIFIC CHALLENGES IN ASSESSMENT OF ENDPS 3.4 SYSTEMS TOXICOLOGY-BASED ASSESSMENT OF ENDPS -- 3.4.1 Predictive Power of Systems Toxicology -- 3.5 A COMPREHENSIVE ASSESSMENT PROGRAM FOR ENDPS -- 3.5.1 Toxicological Assessment Steps -- 3.5.1.1 Step I -- 3.5.1.2 Step II -- 3.5.1.3 Step III -- 3.5.1.4 Step IV -- 3.6 QUALITY CONSIDERATIONS -- 3.6.1 Comparative Studies -- 3.6.2 Exposure and its Verification -- 3.6.2.1 Adequate exposure -- 3.6.2.2 Exposure verification in nonclinical studies -- 3.6.2.3 Exposure verification in clinical studies -- 3.6.3 Independent Peer Review -- 3.7 TRANSPARENT SHARING OF SCIENTIFIC DATA ON ENDP ASSESSMENT Nicotine Toxicology Tobacco Toxicology Electronic cigarettes Safety measures Peitsch, Manuel C. edt Hoeng, Julia edt Erscheint auch als Druck-Ausgabe 9780128204900 Erscheint auch als Druck-Ausgabe 0128204907 Erscheint auch als Druck-Ausgabe 9780128209356 |
| spellingShingle | Toxicological Evaluation of Electronic Nicotine Delivery Products Nicotine Toxicology Tobacco Toxicology Electronic cigarettes Safety measures |
| title | Toxicological Evaluation of Electronic Nicotine Delivery Products |
| title_auth | Toxicological Evaluation of Electronic Nicotine Delivery Products |
| title_exact_search | Toxicological Evaluation of Electronic Nicotine Delivery Products |
| title_exact_search_txtP | Toxicological Evaluation of Electronic Nicotine Delivery Products |
| title_full | Toxicological Evaluation of Electronic Nicotine Delivery Products edited by Manuel C. Peitsch, Julia Hoeng |
| title_fullStr | Toxicological Evaluation of Electronic Nicotine Delivery Products edited by Manuel C. Peitsch, Julia Hoeng |
| title_full_unstemmed | Toxicological Evaluation of Electronic Nicotine Delivery Products edited by Manuel C. Peitsch, Julia Hoeng |
| title_short | Toxicological Evaluation of Electronic Nicotine Delivery Products |
| title_sort | toxicological evaluation of electronic nicotine delivery products |
| topic | Nicotine Toxicology Tobacco Toxicology Electronic cigarettes Safety measures |
| topic_facet | Nicotine Toxicology Tobacco Toxicology Electronic cigarettes Safety measures |
| work_keys_str_mv | AT peitschmanuelc toxicologicalevaluationofelectronicnicotinedeliveryproducts AT hoengjulia toxicologicalevaluationofelectronicnicotinedeliveryproducts |