Current advances in breast cancer research: a molecular approach

Breast cancer is a recognized disease around the world with varying patient outcomes based on the type of breast cancer, access to healthcare and other factors. Survival rates for breast cancer are significantly lower in metastatic cases than localized cases. Early diagnosis and effective treatments...

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Bibliographische Detailangaben
1. Verfasser: Suman, Shankar (VerfasserIn)
Weitere Verfasser: Suman, Garima (MitwirkendeR), Mishra, Sanjay (MitwirkendeR)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Singapore Bentham Books 2020
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Online-Zugang:FUBA2
Zusammenfassung:Breast cancer is a recognized disease around the world with varying patient outcomes based on the type of breast cancer, access to healthcare and other factors. Survival rates for breast cancer are significantly lower in metastatic cases than localized cases. Early diagnosis and effective treatments for the efficient management of breast cancer are now in demand , as they help to prolong patient life. There have been many breakthrough developments in the molecular biology of breast cancer research in recent times. Advancements in diagnostic techniques (imaging and biomarker detection) for breast cancer have improved the screening of the disease and have improved patient outcomes. Despite these enhancements, the disease is still lethal for patients and the search for a cure requires a complete understanding of the disease. Current Advances in Breast Cancer Research: A Molecular Approach presents a comprehensive overview of current basic and translational research on the subject. The 14 chapters of the book give emphasis to current knowledge about breast cancer, ongoing challenges, and innovative research findings by different research groups. Readers will find detailed information about breast cancer biology, genetics, clinical diagnostics and treatments. Additional information for advanced readers in life sciences, such as techniques relevant to genomics (including genetic fingerprinting), proteomics, metabolomics and medicine (such as imaging and molecular diagnostics) is also provided. The combination of both basic and advanced information makes this book a useful reference to the student and researcher, alike, seeking an understanding about breast cancer at a molecular level
Cover -- Title -- Copyright -- End User License Agreement -- Contents -- Foreword -- Preface -- List of Contributors -- Breast Cancer: A Global Burden -- Brij Nath Tewari1,* and Sanjay Mishra2 -- INTRODUCTION -- Statistics at a Glance: The Burden of Cancer Worldwide -- A brief History of Breast Cancer -- Types of Breast Cancer -- GRADING AND MOLECULAR SUBTYPES OF BREAST CANCER -- Breast Cancer Grading -- Breast Cancer Molecular Subtypes -- Luminal A -- Luminal B -- Basal-like -- HER2 Enriched -- SIGNS, SYMPTOMS AND RISK FACTORS OF BREAST CANCER -- Risk Factors of Breast Cancer -- Age -- Geographical Variation -- Previous Benign Breast Cancer -- Age at Menarche and Menopause -- Oral Contraceptives -- Breast-feeding -- Breast Density -- Family History of Breast Cancer -- Personal History of Breast Cancer -- Genetic Risk Factors -- Radiation -- Tobacco -- Alcohol -- Diet -- Hormonal Risk Factor -- TUMOR MARKERS -- Types of Molecular Markers -- Diagnostic Markers -- Prognostic Markers -- Predictive Markers -- Companion Diagnostic Markers -- CURRENT DIAGNOSIS AND TREATMENTS OF BREAST CANCER -- Screening and Diagnosis of Breast Cancer -- Mammography -- Overdiagnosis of Breast Cancer -- Magnetic Resonance Imaging (MRI) -- Breast Ultrasound -- PET Scan -- X-rays -- Biopsy -- Breast Cancer Treatments -- Surgery -- Limitations -- Radiation Therapy -- Internal Radiation Therapy -- Limitations -- Systemic Therapy -- Chemotherapy -- Hormonal Therapy -- Targeted Therapy: Therapy Intended at HER2 -- Other Targeted Drugs -- SUMMARY AND CONCLUDING REMARKS -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENT -- REFERENCES -- Current Imaging Techniques in Breast Cancer: An Overview -- Garima Suman* and Anurima Patra -- INTRODUCTION -- Anatomy of Breast -- Clinical Diagnosis of BC -- Why Imaging? -- RADIOLOGICAL MODALITIES USED IN BC DETECTION.
Beschreibung:Description based on publisher supplied metadata and other sources
Beschreibung:1 Online-Ressource (401 Seiten)
ISBN:9789811451447

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